2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1888B
    Bromfenac sodium hydrate 120638-55-3 99.94%
    Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium hydrate can be used in ocular inflammation research.
    Bromfenac sodium hydrate
  • HY-B2144I
    Chitosan (≥90% deacetylated,viscosity 10 mPa.s) 9012-76-4
    Chitosan (Deacetylated chitin) (≥90% deacetylated,viscosity 10 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated,viscosity 10 mPa.s) can be used as a versatile biomaterial in drug delivery, tissue engineering, and wound healing.
    Chitosan (≥90% deacetylated,viscosity 10 mPa.s)
  • HY-E70079
    Cystathionine β-lyase, Recombinant Microorganisms 9055-05-4
    Cystathionine β-lyase, Recombinant Microorganisms (CBL) is an enzyme that catalyzes the breakdown of cystathionine to homocysteine, the penultimate step in methionine biosynthesis. Cystathionine β-lyase is important for bacterial virulence.
    Cystathionine β-lyase, Recombinant Microorganisms
  • HY-N0005S
    Curcumin-d6 1246833-26-0 99.78%
    Curcumin-d6is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.
    Curcumin-d6
  • HY-N0930B
    Galegine hydrochloride 2368870-39-5
    Galegine hydrochloride, a guanidine derivative, contributes to weight loss in mice. Guanidine hydrochloride is the compound derived from G. officinalis, which gave rise to the biguanides, metformin and phenformin. Galegine hydrochloride activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hydrochloride has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains.
    Galegine hydrochloride
  • HY-N10420
    Hinokinin 26543-89-5 99.38%
    Hinokinin (Compound 1) is a compound isolated from the stems of Hypoestes aristate. Hinokinin exhibits moderate activity of HIV-1 protease enzyme.
    Hinokinin
  • HY-N12257
    Antimycin A2 27220-57-1 ≥99.0%
    Antimycin A2 is the component of the antibiotic antimycin A. Antimycin A is an antibiotic, that exhibits inhibitory activity against fungi and some insects through inhibition of respiration and cytochrome b reoxidation.
    Antimycin A2
  • HY-P10257
    KR-12 (human) 1218951-51-9 99.91%
    KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM.
    KR-12 (human)
  • HY-P1801A
    Cys-TAT(47-57) TFA 98.04%
    Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.
    Cys-TAT(47-57) TFA
  • HY-P2260B
    Tat-beclin 1 scrambled 99.01%
    Tat-beclin 1 scrambled is the scrambled part and a scrambled control of Tat-beclin 1 (HY-P2260), which is derived from a region of the autophagy protein, beclin 1. beclin 1 induces autophagy via binding human immunodeficiency virus, HIV-1 Nef and interacting with negative regulator GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens, such as HIV-1. Tat-beclin 1 also reduces mortality in mice infected with chikungunya or West Nile virus.
    Tat-beclin 1 scrambled
  • HY-P2260C
    Tat-beclin 1 scrambled TFA 98.54%
    Tat-beclin 1 scrambled TFA is the scrambled part and a scrambled control of Tat-beclin 1 (HY-P2260), which is derived from a region of the autophagy protein, beclin 1. beclin 1 induces autophagy via binding human immunodeficiency virus, HIV-1 Nef and interacting with negative regulator GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens, such as HIV-1. Tat-beclin 1 also reduces mortality in mice infected with chikungunya or West Nile virus.
    Tat-beclin 1 scrambled TFA
  • HY-P7061A
    ALX 40-4C Trifluoroacetate
    ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.
    ALX 40-4C Trifluoroacetate
  • HY-P99770
    Omodenbamab 2241724-48-9
    Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection.
    Omodenbamab
  • HY-U00058
    Diflucortolone valerate 59198-70-8 ≥98.0%
    Diflucortolone valerate is a powerful corticosteroid used topically for the research of various skin diseases.
    Diflucortolone valerate
  • HY-Y0366S
    Lauric acid-13C 93639-08-8 99.80%
    Lauric acid-13C is the 13C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-13C
  • HY-100711A
    Prodigiosin hydrochloride 56144-17-3 98.00%
    Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties.
    Prodigiosin hydrochloride
  • HY-105967A
    Dicresulene diammonium 99.48%
    Dicresulene diammonium is an impurity of Policresulen, an organic acid with hemostatic, antimicrobial and antiviral activities.
    Dicresulene diammonium
  • HY-108062A
    BLI-489 hydrate 2580120-08-5 ≥99.0%
    BLI-489 hydrate, a penem β-lactamase inhibitor, is active against class A and class C as well as some class D β-lactamases. The combination of Piperacillin and BLI-489 hydrate is efficacious against murine infections caused by class A (including extended-spectrum β-lactamases), class C (AmpC), and class D β-lactamase-expressing pathogens.
    BLI-489 hydrate
  • HY-128036B
    ddATP trisodium 72029-21-1 ≥98.0%
    ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection.
    ddATP trisodium
  • HY-131069A
    MBX2329 1438272-42-4 99.90%
    MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains.
    MBX2329
Cat. No. Product Name / Synonyms Application Reactivity