2. Anti-infection
  3. Flavivirus
  4. TYT-1

TYT-1 is a sulfonamide-thiourea compound that has inhibitory activity against West Nile virus replication with a 50% effective concentration of 0.7 microM, blocking a post-entry, pre-assembly step of viral replication.

For research use only. We do not sell to patients.

TYT-1

TYT-1 Chemical Structure

CAS No. : 64803-10-7

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TYT-1 Related Antibodies

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Description

TYT-1 is a sulfonamide-thiourea compound that has inhibitory activity against West Nile virus replication with a 50% effective concentration of 0.7 microM, blocking a post-entry, pre-assembly step of viral replication.

Cellular Effect
Cell Line Type Value Description References
Vero CC50
> 70 μM
Compound: TYT-1
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
[PMID: 17452483]
Vero CC50
> 70 μM
Compound: TYT-1
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
[PMID: 17452483]
Vero EC50
0.7 μM
Compound: TYT-1
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
[PMID: 17452483]
Vero EC50
7 μM
Compound: TYT-1
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
[PMID: 17452483]
Molecular Weight

439.57

Formula

C21H17N3O2S3
CAS No.
SMILES

S=C(N(C1=CC=CC=C1)C2=CC=CC=C2)/N=C(N3C4=CC=CC=C4)\SCS3(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TYT-1 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TYT-164803-10-7TYT1TYT 1FlavivirusInhibitorinhibitorinhibit

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TYT-1
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HY-122196
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