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Pathways Recommended:	PI3K/Akt/mTOR

Results for "

serum K

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (1) Biochemical Assay Reagents (1) Endogenous Metabolite (1) Glucocorticoid Receptor (2) Interleukin Related (1) JAK (1) MMP (2) mTOR (1) Reference Standards (1) STAT (1) VKOR (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (1) Metabolic Disease (1)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

MCE Kits

Natural
Products

Antibodies

Oligonucleotides

Targets Recommended: SGK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112961

Patiromer	JAK Interleukin Related STAT	Metabolic Disease
Patiromer is an orally active, selective and non-absorbable intestinal potassium (K ⁺) polymer binder that reversibly binds potassium ions in exchange for calcium (Ca ²⁺). Patiromer can rapidly and continuously reduce serum potassium levels, maintain a normal blood potassium state, and reduce serum aldosterone levels. Patiromer also increases fecal potassium excretion. Patiromer is mainly used in the study of hyperkalemia associated with diseases such as chronic kidney disease, diabetes, and heart failure, and is particularly suitable for improving renin-angiotensin-aldosterone system inhibitor (RAASi) therapy .

HY-111186

Flocoumafen WL 108366	Glucocorticoid Receptor MMP VKOR	Others
Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .

HY-134508

C24-Ceramide	mTOR	Cancer
C24-Ceramide is an orally active competitive binding agonist of *PIP4K2C* (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .

HY-148162

Kayexalate	Biochemical Assay Reagents	Others
Kayexalate, a cation-exchange resin, is an orally active plasma potassium inhibitor. Kayexalate can be used in the research of hyperkalemia .

HY-105213

YM-17K MC-352	Antibiotic Bacterial	Infection
YM-17K (MC-352) is a macrolide antibiotic. YM-17K exhibits antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and anaerobic bacteria. YM-17K exhibits stable activity in serum and is less affected by pH values .

HY-135541

Darexaban maleate YM150 maleate	Endogenous Metabolite	Cardiovascular Disease
Darexaban maleate (YM150 maleate) is a direct factor Xa inhibitor with activity in preventing venous thromboembolism. The major metabolite of Darexaban maleate in humans is Darexaban glucitol, which acts pharmacologically. The glucitolation reaction of Darexaban maleate is mainly catalyzed by UGT1A9 and UGT1A10 in the human liver and intestine. The K(m) value of Darexaban maleate glucitolation in the liver is greater than 250 μM, while in the intestine it exhibits substrate inhibition kinetics with a K(m) value of 27.3 μM. The unbound K(m) value of Darexaban maleate is significantly reduced by the influence of fatty acid-free bovine serum albumin in both HLM and UGT1A9 .

HY-111186R

Flocoumafen (Standard) WL 108366 (Standard)	Reference Standards VKOR Glucocorticoid Receptor MMP	Others
Flocoumafen (Standard) is the analytical standard of Flocoumafen. This product is intended for research and analytical applications. Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .

HY-113513

5-HEPE	Others	Cancer
5(S)-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.

Cat. No.	Product Name	Type

HY-134508

C24-Ceramide	Drug Delivery
C24-Ceramide is an orally active competitive binding agonist of *PIP4K2C* (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .

C24-Ceramide

Drug Delivery

C24-Ceramide is an orally active competitive binding agonist of PIP4K2C (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .

Exosome-Specific 293 Cell Medium Supplement
MCE Exosome-Specific 293 Cell Medium Supplement is designed as a feed supplement for use with the Exosome-Specific 293 Cell Medium (Serum-Free) (MCE Cat. No.: HY-K3113).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113513

5-HEPE	Microorganisms Source classification	Others
5(S)-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P85914

	Galectin-3 Antibody (YA5606) 90K; 90K MAC 2 BP; Basement membrane autoantigen p105; BTBD17B; Galectin 3 binding protein; Galectin-3-binding protein; L3 antigen; Lectin galactoside binding soluble 3 binding protein; Lectin galactoside-binding soluble 3-binding protein; LG3BP_HUMAN; LGALS3BP; M2BP; Mac 2 binding protein; Mac 2 BP; Mac-2 BP; Mac-2-binding protein; Mac2 BP; MAC2BP; serum protein 90K; TANGO10B; Transport and golgi organization 10 homolog B; Tumor associated antigen 90K; Tumor-associated antigen 90K	IHC-P, WB, ICC/IF, ELISA	Human
	Galectin-3 Antibody (YA5606) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Galectin-3.

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Cat. No.	Product Name		Classification

HY-134508

C24-Ceramide		Phospholipids
C24-Ceramide is an orally active competitive binding agonist of *PIP4K2C* (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .

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serum K

Inhibitors & Agonists

Biochemical Assay Reagents

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Antibodies

Oligonucleotides

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