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Results for "

sGC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AAK1 (2) Akt (1) Apoptosis (13) Biochemical Assay Reagents (2) c-Met/HGFR (2) Calmodulin (1) Casein Kinase (2) CDK (2) CHIKV (1) CMV (1) Cyclin G-associated Kinase (GAK) (1) DAPK (1) Deubiquitinase (1) Drug Derivative (1) Elastase (3) Endogenous Metabolite (1) Epigenetic Reader Domain (4) Flavivirus (1) Fluorescent Dye (1) GSK-3 (1) Guanylate Cyclase (41) HDAC (1) Histone Acetyltransferase (1) Histone Methyltransferase (9) HSP (2) Interleukin Related (1) Isotope-Labeled Compounds (3) LDLR (1) Microtubule/Tubulin (8) Monoamine Oxidase (6) NF-κB (1) NO Synthase (7) Parasite (1) Phosphodiesterase (PDE) (2) PKG (1) Potassium Channel (1) Reactive Oxygen Species (ROS) (1) Reference Standards (7) Small Interfering RNA (siRNA) (2) STAT (1) Virus Protease (2) Wnt (2) YAP (1)
By Research Areas:	Cancer (53) Cardiovascular Disease (29) Infection (9) Inflammation/Immunology (15) Metabolic Disease (7) Neurological Disease (11)
Oligonucleotides:	Aptamers (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112445

SGC3027 3 Publications Verification	Histone Methyltransferase	Cancer
SGC3027 is a histone methyltransferase inhibitor . SGC3027 is the first potent, selective and cell active chemical probe for PRMT7 .

HY-114211

SGC8158	Histone Methyltransferase HSP	Cancer
SGC8158 is an inhibitor of PRMT7 and can be used to study the cellular function of PRMT7. SGC8158 decreases monomethylarginine levels of Hsp70 (the best characterized PRMT7 substrate). SGC8158 induces growth inhibition in various cancer cells (IC₅₀: 2-9 μM), as well as multidrug-resistant (MDR) cancer cells. SGC8158 also enhances Doxorubicin (HY-15142A) induced DNA damage and Its cytotoxicity .

HY-122186

SGC-GAK-1 1 Publications Verification	Cyclin G-associated Kinase (GAK)	Cancer
SGC-GAK-1 is a potent, selective cyclin G-associated kinase (GAK) inhibitor with a K_i of 3.1 nM. SGC-GAK-1 is a chemical probe for GAK .

HY-155697

SGC-UBD253	HDAC	Cancer
SGC-UBD253, a chemical probe, is a potent HDAC6-UBD antagonist. SGC-UBD253 can be used in research of cancer .

HY-100565

SGC2085 1 Publications Verification	Histone Methyltransferase	Cancer
SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC₅₀ of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC₅₀ value of 5.2 μM, but not other PRMT proteins .

HY-158146

sGC activator 1	Guanylate Cyclase	Cancer
sGC activator 1 (example 10B) is an activator of soluble guanylate cyclase (SGC) .

HY-126300A

SGC6870N	Histone Methyltransferase	Cancer
SGC6870N is inactive against PRMT6 and can be utilized as a negative control. SGC6870N is an inactive enantiomer of SGC6870 (HY-126300) .

HY-176822

SGC-BRDVIII-NC	Epigenetic Reader Domain	Others
SGC-BRDVIII-NC (Compound 35) is a negative control compound of SMARCA2/4 and PB1 bromodomain (BRD) inhibitor. SGC-BRDVIII-NC completely abolishes protein-ligand binding capacity with the methylation of the phenolic hydroxyl moiety. SGC-BRDVIII-NC can be used for adipogenesis research .

HY-142697

SGC agonist 1	Guanylate Cyclase	Cardiovascular Disease
SGC agonist 1 is a potent agonist of soluble guanylate cyclase (SGC). SGC agonist 1 improves solubility combined with high cell permeability. SGC agonist 1 has the potential for the research of cardiovascular disease (extracted from patent WO2016030354A1, compound 18A) .

HY-100565A

SGC2085 hydrochloride	Histone Methyltransferase	Cancer
SGC2085 hydrochloride is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC₅₀ of 50 nM. SGC2085 hydrochloride also selectively inhibits PRMT6 with an IC₅₀ value of 5.2 μM, but not other PRMT proteins .

HY-15650

SGC0946 5+ Cited Publications	Histone Methyltransferase	Cancer
SGC0946 is a selective DOT1L inhibitor with an IC₅₀ value of 0.3 nM. By inhibiting DOT1L, SGC0946 can induce G1 phase arrest, suppress cell self-renewal and metastatic potential, and induce cell differentiation in cancer cells. SGC0946 can be used in the research of tumors such as leukemia and breast cancer, and also serves as a probe to further investigate the cellular mechanisms of DOT1L in normal and diseased cells .

HY-142698

SGC agonist 2	Guanylate Cyclase	Cardiovascular Disease
SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031) .

HY-123940

SGC-AAK1-1	Wnt AAK1	Cancer
SGC-AAK1-1, a chemical probe, is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC₅₀ of 270 nM and a K_i of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1 .

HY-168341

sGC activator 2	Guanylate Cyclase	Inflammation/Immunology
sGC activator 2 (Compound 16a) is an activator for soluble guanylate cyclase (sGC), that promotes the cGMP production and exhibits vascular protective and anti-inflammatory activities .

HY-145446

SGC-SMARCA-BRDVIII	Epigenetic Reader Domain	Metabolic Disease
SGC-SMARCA-BRDVIII, a chemical probe, is a potent and selective inhibitor of SMARCA2/4 and PB1(5), with K_ds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3), with K_ds of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts .

HY-15650A

SGC0946 TFA	Histone Methyltransferase	Cancer
SGC0946 TFA is a selective DOT1L inhibitor with an IC₅₀ value of 0.3 nM. By inhibiting DOT1L, SGC0946 TFA can induce G1 phase arrest, suppress cell self-renewal and metastatic potential, and induce cell differentiation in cancer cells. SGC0946 TFA can be used in the research of tumors such as leukemia and breast cancer, and also serves as a probe to further investigate the cellular mechanisms of DOT1L in normal and diseased cells .

HY-126300

SGC6870 1 Publications Verification	Histone Methyltransferase	Cancer
SGC6870, a chemical probe, is a potent, selective and cytoactive allosteric inhibitor of PRMT6 with IC₅₀ of 77 nM .

HY-178335

SGC-CK1γ-1	LDLR Wnt CMV	Infection
SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection .

HY-112804

SGC-iMLLT 1 Publications Verification	Epigenetic Reader Domain	Cancer
SGC-iMLLT is a first-in-class chemical probe and a potent, selective inhibitor of MLLT1/3-histone interactions with an IC₅₀ of 0.26 μM. SGC-iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9/YEATS3) with K_ds of 0.129 and 0.077 μM, respectively .

HY-168905

SGC-CAMKK2-1	Calmodulin	Cancer
SGC-CAMKK2-1, a chemical probe, is the selective, inhibitor for calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC₅₀ of 30 nM. SGC-CAMKK2-1 inhibits AMPK phosphorylation in cell C4-2 with an IC₅₀ of 1.6 μM .

HY-153708

SGC-CLK-1 CAF-170	CDK	Cancer
SGC-CLK-1, a chemical probe, is a potent and selective inhibitor of Cdc2-like kinases CLK1, CLK2, and CLK4. SGC-CLK-1 can inhibit the growth of melanoma and glioblastoma cells .

HY-19715

SGC707 5+ Cited Publications	Histone Methyltransferase	Metabolic Disease
SGC707, a chemical probe, is a potent, selective, and non-competitive PRMT3 (protein arginine methyltransferase 3) inhibitor (IC₅₀=31 nM, K_d=53 nM).

HY-160065

sgc8c aptamer sodium	Biochemical Assay Reagents	Cancer
sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. sgc8c aptamer sodium can precisely bring the nanotags connected to it to the surface of cells expressing PTK-7, thus achieving specific recognition and labeling of target cells .

HY-139004

SGC-CK2-1 4 Publications Verification	Casein Kinase	Neurological Disease
SGC-CK2-1 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC₅₀s of 36 and 16 nM for CK2α and CK2α′respectively in the nanoBRET assay. SGC-CK2-1 can be used for the research of neurodegenerative diseases .

HY-15826

SGC-CBP30 15+ Cited Publications	Epigenetic Reader Domain Histone Acetyltransferase	Inflammation/Immunology Cancer
SGC-CBP30, a chemical probe, is a potent and highly selective CBP/p300 bromodomain (K_ds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects .

HY-168050

SGC-NSP2PRO-1	CHIKV Virus Protease	Infection
SGC-NSP2PRO-1 is a potent irreversible covalent inhibitor of Chikungunya (CHIKV) nsP2 cysteine protease with an IC₅₀ value of 60 nM. SGC-NSP2PRO-1 demonstrates potent antialphavirus activity, inhibiting CHIKV and VEEV replication with EC₅₀ = 0.01 and 0.3 µM, respectively .

HY-147083

SGC-AAK1-1N	AAK1	Cancer
SGC-AAK1-1N is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor, with an IC₅₀ of 1.8 μM .

HY-156350

SGC-STK17B-1	DAPK	Cancer
SGC-STK17B-1, a chemical probe, is an ATP-competitive and selective STK17B (a member of DAPK family) inhibitor (IC₅₀: 34 nM, K_D: 5.6 nM) .

HY-176268

SGC-NSP2hel-1 RA-0188293; RA-NSP2-1	Virus Protease Flavivirus	Infection
SGC-NSP2hel-1 (RA-0188293), a chemical probe, is a potent, specific and orally active nsP2 inhibitor. SGC-NSP2hel-1 has broad spectrum activity against multiple alphaviruses of the nsP2 helicase with a CC₅₀ > 250 μM. SGC-NSP2hel-1 (RA-0188293) shows selectivity index > 4000 against human RNA helicases. SGC-NSP2hel-1 reduces virus replication and limited virus-induced pathology by forming a stable complex with nsP2 and ATP in a preclinical small animal model of CHIKV disease.

HY-162653

SGC-CDKL2/AAK1/BMP2K-1		Others
SGC-CDKL2/AAK1/BMP2K-1 (Compound 9) is a potent and selective CDKL2 (Cyclin-dependent kinase-like 2) inhibitor with an IC₅₀ value of 460 nM. CDKL2 is involved in various biological processes such as tumorigenesis, development, and viral infections. SGC-CDKL2/AAK1/BMP2K-1 serves as a powerful tool for studying the biological functions of CDKL2 and holds promise for research in fields related to cancer, infections, and other diseases .

HY-155805

SGC-CAF382-1	CDK	Cancer
CAF-382 (compound B1) is an analog of SNS-032 and a CDKL5 and pan-CDK inhibitor with a weak GSK3α/β affinity (>1.8 μM) and inhibitory activity. CAF-382 inhibits CDKL5 and blocks the phosphorylation of the CDKL5 E2 domain .

HY-172118

SGC-CDKL5/GSK3	GSK-3	Neurological Disease
CDKL5/GSK3-IN-1 (Compound 2) is a potent and selectivity chemical probe for CDKL5/GSK3.CDKL5/GSK3-IN-1 has potent inhibition of CDKL5 and GSK3α/β, with IC₅₀ values of 4.6, 24 and 9.5 nM for CDKL5, GSK3β and GSK3α, respectively, in the NanoBRET assay. CDKL5/GSK3-IN-1 can be used for the research of CNS diseases .

HY-172193

UBD1031 sGC-UBD1031	Deubiquitinase	Others
UBD1031 exhibits good affinity to the ubiquitin binding domain (UBD) of USP16 with a K_D of 48 nM. UBD1031 inhibits the interaction between USP16 and ISG15 with an EC₅₀ of 1.7 nM. UBD1031 can be used a chemical probe for USP16 UBD .

HY-RS12791

SGCB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SGCB Human Pre-designed siRNA Set A contains three designed siRNAs for SGCB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SGCB Human Pre-designed siRNA Set A SGCB Human Pre-designed siRNA Set A

HY-159484

*Hsp110/sGC-modulator-1*	HSP Guanylate Cyclase	Cardiovascular Disease
Hsp110/sGC-modulator-1 (compound 17i), an orally active *Hsp110/sGC* dual-target regulator, exhibits optimal Hsp110 and sGC molecular activities as well as remarkable cell malignant phenotypes inhibitory and vasodilatory effects. Hsp110/sGC-modulator-1 (compound 17i) attenuates pulmonary vascular remodeling and right ventricular hypertrophy via Hsp110 suppression .

HY-160065F

*FAM-sgc8c aptamer sodium*	Fluorescent Dye Biochemical Assay Reagents	Cancer
FAM-sgc8c aptamer sodium is a 5-FAM labeled sgc8c aptamer sodium (HY-160065). sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. Binding of FAM-sgc8c aptamer sodium to PTK-7 induces the assembly of nanotags on the cell surface, resulting in strong fluorescence and SERS signals .

HY-17500

Ataciguat HMR-1766	Guanylate Cyclase	Cardiovascular Disease
Ataciguat (HMR-1766) is a nitric oxide-independent soluble guanylate cyclase (sGC) activator. Ataciguat is able to activate the ferric heme-iron redox form of sGC that stimulate the production of cyclic GMP (cGMP). Ataciguat exhibits vasodilator effects .

HY-111516

MGV354	Guanylate Cyclase	Cardiovascular Disease Inflammation/Immunology
MGV354 is a soluble guanylate cyclase (sGC) activator with EC₅₀s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively .

HY-107546

CFM 1571 hydrochloride	Guanylate Cyclase	Cardiovascular Disease
CFM 1571 hydrochloride is the stimulator of the nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC₅₀ and IC₅₀ of 5.49 μM and 2.84 μM, respectively. Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). CFM 1571 hydrochloride has the potential for the research of cardiovascular and other diseases .

HY-117917

(Rac)-MGV354	Guanylate Cyclase	Cardiovascular Disease Inflammation/Immunology
(Rac)-MGV354 is the racemate of MGV354. MGV354 is a soluble guanylate cyclase (sGC) activator with EC₅₀s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively .

HY-W013386

LY83583 1 Publications Verification	Guanylate Cyclase	Cardiovascular Disease Neurological Disease Cancer
LY83583 is inhibitor of soluble guanylate cyclase (sGC) with the ability to target the cGMP signaling pathway. LY83583 inhibits the kinase activity-related proliferation of tumor cells by inducing the Cdk inhibitor p21. LY83583 can be used for the study of cancers (colorectal cancer, breast cancer and melanoma) and cardiovascular disease .

HY-W062836

BAY 41-8543	Guanylate Cyclase	Cardiovascular Disease
BAY 41-8543 is an orally active, nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). BAY 41-8543 has vasodilator activity in the pulmonary and systemic vascular beds in the rat. BAY 41-8543 has antiplatelet effects and has the potential for cardiovascular diseases research .

HY-B1359

Methylene blue trihydrate 15+ Cited Publications C.I. Basic Blue 9 trihydrate	Guanylate Cyclase Monoamine Oxidase NO Synthase Parasite	Infection Neurological Disease Cancer
Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment .

HY-109066

Olinciguat IW-1701	Guanylate Cyclase	Cardiovascular Disease
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay .

HY-N10201

Cytoglobosin C	Endogenous Metabolite	Cancer
Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC₅₀<10 μM) .

HY-117962

(Rac)-BI 703704	Guanylate Cyclase	Metabolic Disease
(Rac)-BI 703704 is a potent soluble guanylyl cyclase (sGC) activator. (Rac)-BI 703704 reduces progression of renal damage in the ZSF1 rat, and highlight the potential of sGC activation as an effective therapy for diabetic nephropathy .

HY-113926

BAY 60-2770	Guanylate Cyclase	Cardiovascular Disease
BAY 60-2770 is a potent, selective, and orally active soluble guanylyl cyclase (sGC) activator. BAY 60-2770 increases the activity of sGC in a nitric oxide-independent manner. BAY 60-2770 shows antifibrotic effect .

HY-N7980

Rubipodanone A	NF-κB	Cancer
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .

HY-14181

Cinaciguat 3 Publications Verification BAY 58-2667	Guanylate Cyclase	Cardiovascular Disease
Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.

HY-RS17592

Srgn Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Srgn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srgn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Srgn Mouse Pre-designed siRNA Set A Srgn Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-14536

Methylene Blue

15+ Cited Publications

Basic Blue 9; CI-52015; Methylthioninium chloride

Chromogenic Assays

Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene Blue is a photosensitizer and redox agent. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .

HY-14536A

Methylene blue (purity≥70%)

Basic Blue 9 (purity≥70%); CI-52015 (purity≥70%); Methylthioninium chloride (purity≥70%)

Chromogenic Assays

Methylene blue (purity≥70%) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue (purity≥70%) is a vasopressor and is often used as a dye in several medical procedures. Methylene blue (purity≥70%) through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue (purity≥70%) is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue (purity≥70%) is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .

HY-160065F

*FAM-sgc8c aptamer sodium*	Fluorescent Dyes/Probes
FAM-sgc8c aptamer sodium is a 5-FAM labeled sgc8c aptamer sodium (HY-160065). sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. Binding of FAM-sgc8c aptamer sodium to PTK-7 induces the assembly of nanotags on the cell surface, resulting in strong fluorescence and SERS signals .

HY-14536R

Methylene Blue (Standard)

Basic Blue 9 (Standard); CI-52015 (Standard); Methylthioninium chloride (Standard)

Chromogenic Assays

Methylene Blue (Standard) is the analytical standard of Methylene Blue. This product is intended for research and analytical applications. Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7980

Rubipodanone A	Quinones Classification of Application Fields Rubia podantha Source classification Rubiaceae Plants Naphthalene Quinones Disease Research Fields Cancer	NF-κB
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .

HY-W015084

β-Ionone 1 Publications Verification	Classification of Application Fields Viola odorata Linn. Ketones, Aldehydes, Acids Source classification Violaceae Plants Disease Research Fields Cancer	Apoptosis
β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-W015084A

(E)-β-Ionone β-Lonone	Viola odorata Linn. Terpenoids Sesquiterpenes Source classification Violaceae Plants	Apoptosis
(E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-N10201

Cytoglobosin C	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids Cancer	Endogenous Metabolite
Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC₅₀<10 μM) .

HY-N1841

Rocaglamide D 3'-Hydroxyrocaglamide	Source classification Lignans Aglaia odorata Lour. Phenylpropanoids Plants Meliaceae	Others
Rocaglamide D (3'-Hydroxyrocaglamide) (compound 1) is a lignan that can be found in Aglaia odorata. Rocaglamide D shows cytotoxicity with IC₅₀s of 0.32, 0.12, 0.25 µM for HeLa, SGC-7901, A549 cells, respectively .

HY-N9046

Citroside A	Natural Products Source classification Hydrangeaceae Plants	NO Synthase
Citroside A is a megastigmane sesquiterpenoid with cytotoxic and anti-inflammatory activities. Citroside A displays potential effects against NO production with an IC₅₀ of 34.25 μM. Citroside A exhibits pronounced cytotoxicity against SGC-7901 and HeLa cells with IC₅₀ values of 27.52 μM and 29.51 μM, respectively .

HY-W015084R

β-Ionone (Standard)	Viola odorata Linn. Ketones, Aldehydes, Acids Source classification Violaceae Plants	Reference Standards Apoptosis
β-Ionone (Standard) is the analytical standard of β-Ionone. This product is intended for research and analytical applications. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-N13136

Timosaponin D	Triterpenes Liliaceae Terpenoids Source classification Anemarrhena asphodeloides Bunge Plants	Others
Timosaponin D, a natural steroid saponin, can be obtained from the rhizome of Anemarrhena asphodeloides. The IC₅₀ values of Timosaponin D against HepG2 and SGC7901 cells are 43.90 and 57.90 μM, respectively. Timosaponin D can be used in anticancer research .

HY-W015084AR

(E)-β-Ionone (Standard) β-Lonone (Standard)	Microorganisms Viola odorata Linn. Terpenoids Sesquiterpenes Source classification Violaceae Plants	Apoptosis Reference Standards
(E)-β-Ionone (Standard) is the analytical standard of (E)-β-Ionone. This product is intended for research and analytical applications. (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

Cat. No.	Product Name	Chemical Structure

HY-14779S

Riociguat-13C,d6
Riociguat- ¹³C,d₆ is the ¹³C and deuterium labeled Riociguat (HY-14779). Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.

HY-14779S3

Riociguat-d3
Riociguat-d₃ (BAY 632521-d₃) is deuterium labeled Riociguat. Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.

HY-W015084S

β-Ionone-13C3
β-Ionone- ¹³C₃ is the ¹³C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82402

	Guanylyl Cyclase beta 1 Antibody (YA2147) GCbeta1; GCS beta 1; GCS beta 3; GUC1B3; GUCSB3; GUCY1B1; Gucy1b1; GUCY1B3; sGC	WB, IHC-P	Human, Mouse, Rat
	Guanylyl Cyclase beta 1 Antibody (YA2147) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Guanylyl Cyclase beta 1.

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Cat. No.	Product Name		Classification

HY-160065

sgc8c aptamer sodium		Aptamers
sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. sgc8c aptamer sodium can precisely bring the nanotags connected to it to the surface of cells expressing PTK-7, thus achieving specific recognition and labeling of target cells .

HY-RS12791

SGCB Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SGCB Human Pre-designed siRNA Set A contains three designed siRNAs for SGCB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17592

Srgn Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Srgn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srgn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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