2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. UBD1031

UBD1031 exhibits good affinity to the ubiquitin binding domain (UBD) of USP16 with a KD of 48 nM. UBD1031 inhibits the interaction between USP16 and ISG15 with an EC50 of 1.7 nM. UBD1031 can be used a chemical probe for USP16 UBD.

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UBD1031 Chemical Structure

UBD1031 Chemical Structure

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UBD1031 Related Antibodies

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USP1 USP2 USP7 USP8 USP30 UCHL1

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Description

UBD1031 exhibits good affinity to the ubiquitin binding domain (UBD) of USP16 with a KD of 48 nM. UBD1031 inhibits the interaction between USP16 and ISG15 with an EC50 of 1.7 nM. UBD1031 can be used a chemical probe for USP16 UBD[1].

Molecular Weight

449.84

Formula

C21H18ClF2N3O4
SMILES

OC(CCC1=NC2=C(C(N1CC(N[C@@H](C)C3=C(C=CC=C3F)F)=O)=O)C=CC=C2Cl)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UBD1031 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UBD1031UBD 1031UBD-1031DeubiquitinaseDUBsInhibitorinhibitorinhibit

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