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Results for "

pyrimidine synthesis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (22) Acyltransferase (1) Antibiotic (1) Apoptosis (12) Autophagy (9) Bacterial (3) Biochemical Assay Reagents (2) Dihydroorotate Dehydrogenase (7) Drug Intermediate (9) Drug Metabolite (2) E3 Ligase Ligand-Linker Conjugates (2) Endogenous Metabolite (32) HIV (7) IFNAR (2) Influenza Virus (1) Isotope-Labeled Compounds (11) Ligands for E3 Ligase (4) Nucleoside Antimetabolite/Analog (53) Parasite (2) PROTAC Linkers (4) Reference Standards (8) SARS-CoV (1) Thymidylate Synthase (3)
By Research Areas:	Cancer (34) Infection (11) Inflammation/Immunology (6) Metabolic Disease (11) Neurological Disease (9)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Nucleotides and their Analogs (2) Nucleosides and their Analogs (26) C (2)

Inhibitors & Agonists

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MCE Kits

Natural
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Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: DNA/RNA Synthesis

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6961

Lapachol 2 Publications Verification	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-W043311

Methyl pyrimidine-4-carboxylate pyrimidine-4-carboxylicacidmethylester	Drug Intermediate	Others
Methyl pyrimidine-4-carboxylate (Pyrimidine-4-carboxylicacidmethylester) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W017769

4-Pyrimidine methanamine Pyrimidin-4-ylmethanamine	Drug Intermediate	Others
4-Pyrimidine methanamine (Pyrimidin-4-ylmethanamine) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-52102

2-(Chloromethyl)pyrimidine hydrochloride	Drug Intermediate	Others
2-(Chloromethyl)pyrimidine hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.

HY-78975

2-(Hydroxymethyl)-pyrimidine	Drug Intermediate	Others
2-(Hydroxymethyl)-pyrimidine is a synthetic intermediate useful for pharmaceutical synthesis.

HY-N6961R

Lapachol (Standard)	Reference Standards Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-152980

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154046

4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154122

6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154047

6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152986

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154002

4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154008

6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-159592

Piperazine-Pyrimidine-Cyclohexane-COOEt	PROTAC Linkers	Cancer
Piperazine-Pyrimidine-Cyclohexane-COOEt is a PROTAC linker. Piperazine-Pyrimidine-Cyclohexane-COOEt can be used in the synthesis of PROTAC SMARCA2/4-degrader-1 (HY-159452) .

HY-154005

4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152977

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-B0083

Leflunomide 10+ Cited Publications HWA486; RS-34821; SU101	Dihydroorotate Dehydrogenase Endogenous Metabolite Bacterial	Cancer
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-W017930

5,7-Dichlorothiazolo[5,4-d]pyrimidine 5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine	Drug Intermediate	Others
5,7-Dichlorothiazolo[5,4-d]pyrimidine (5,7-dichloro-[1,3]thiazolo[5,4-d]pyriMidine) is a building block in the chemical synthesis.

HY-159575

COOEt-cyclohexane-C-Ph-pyrimidine-diazabicyclo	PROTAC Linkers	Cancer
COOEt-cyclohexane-C-Ph-pyrimidine-diazabicyclo is a PROTAC linker. COOEt-cyclohexane-C-Ph-pyrimidine-diazabicyclo can be used in the synthesis of PROTAC SMARCA2/4-degrader-5 (HY-159456) .

HY-W002339

3-Hydroxy-2-methylpyridine	DNA/RNA Synthesis	Others
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

HY-152990

Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate	Nucleoside Antimetabolite/Analog	Others
Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152987

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Nucleoside Antimetabolite/Analog	Others
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-101400S4

Deoxycytidine triphosphate-13C9 dilithium dCTP-¹³C₉ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹³C₉ dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹³C₉ (dCTP- ¹³C₉ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉) dilithium is ¹³C-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium dCTP-¹³C₉,¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹³C₉,¹⁵N₃ dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400A

Deoxycytidine triphosphate (trisodium) solution (100mM) 1 Publications Verification dCTP (trisodium) solution (100mM); 2′-Deoxycytidine-5′-triphosphate (trisodium) solution (100mM)	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-101400

Deoxycytidine triphosphate dCTP; 2′-Deoxycytidine-5′-triphosphate	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium dCTP-¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹⁵N₃ dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S

Deoxycytidine triphosphate-d14 dilithium dCTP-d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-d₁₄ dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate-d₁₄ (dCTP-d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-d₁₄) dilithium is deuterium labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S1

Deoxycytidine triphosphate-15N3,d14 dilithium dCTP-¹⁵N₃,d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹⁵N₃,d₁₄ dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹⁵N₃,d₁₄ (dCTP- ¹⁵N₃,d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃,d₁₄) dilithium is deuterium and ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-15405

Teriflunomide 10+ Cited Publications A77 1726	Drug Metabolite	Inflammation/Immunology
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits **pyrimidine synthesis** and therefore potently decreases T cell and B cell proliferation.

HY-B0003

Gemcitabine hydrochloride 190+ Cited Publications LY 188011 hydrochloride	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Autophagy Apoptosis	Cancer
Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .

HY-17026

Gemcitabine 190+ Cited Publications LY 188011	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Autophagy Apoptosis	Cancer
Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .

HY-161201

Thalidomide-piperazine-pyrimidine-piperazine-C-boc	Ligands for E3 Ligase Autophagy	Cancer
Thalidomide-piperazine-pyrimidine-piperazine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-pyrimidine-piperazine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-42045

Pyrimidine-5-boronic acid pinacol ester	Biochemical Assay Reagents	Others
Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. At the same time, it should be noted that it may be a genotoxic impurity (GTIs) .

HY-161500

Thalidomide-NHCH2-Ph-pyrimidine-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NHCH2-Ph-pyrimidine-NH2 is a conjugate of E3 ligase ligand and linker, which is consisted of a Thalidomide (HY-14658) and a Linker Boc-NHCH2-Ph-pyrimidine-NH2 (HY-161499). Thalidomide-NHCH2-Ph-pyrimidine-NH2 is utilized for synthesis of PROTAC molecule XYD198 (HY-161498) .

HY-Y1298

Methyl acetylacetate 1 Publications Verification Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases .

HY-B0083R

Leflunomide (Standard) HWA486 (Standard); RS-34821 (Standard); SU101 (Standard)	Reference Standards Dihydroorotate Dehydrogenase Endogenous Metabolite Bacterial	Cancer
Leflunomide (Standard) is the analytical standard of Leflunomide. This product is intended for research and analytical applications. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-159684

3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin	PROTAC Linkers	Cancer
3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin is a PROTAC linker. 3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin can be used in the synthesis PROTAC SMARCA2/4-degrader-30 (HY-162748) .

HY-157760

(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH	Ligands for E3 Ligase Autophagy	Cancer
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-152685

4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide	Nucleoside Antimetabolite/Analog	Others
4-Amino-1-(β-D-ribofurano syl)-7H-pyrrolo [2.3-d] pyrimidine-5-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-B0083S1

Leflunomide-13C6 HWA486-¹³C₆; RS-34821-¹³C₆; SU101-¹³C₆	Isotope-Labeled Compounds Dihydroorotate Dehydrogenase Bacterial Endogenous Metabolite	Cancer
Leflunomide- ¹³C₆ (HWA486- ¹³C₆) is ¹³C labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-B0158

Cytidine 5+ Cited Publications Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Neurological Disease
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-169499

(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic Acid	Acyltransferase	Metabolic Disease
(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic Acid is an intermediate in the synthesis of the diacylglycerol acyltransferase 2 (DGAT-2) inhibitor Ervogastat.

HY-159682

3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin	PROTAC Linkers	Cancer
3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin is a PROTAC linker. 3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin can be used in the synthesis PROTAC SMARCA2/4-degrader-29 (HY-162743) .

HY-43791

4-Amino-6-bromo-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	Drug Intermediate	Others
4-Amino-6-bromo-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile is a drug intermediate for synthesis of various active compounds.

HY-42451

2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde	Drug Intermediate	Others
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde is a drug intermediate for synthesis of various active compounds.

HY-B0003R

Gemcitabine hydrochloride (Standard) LY 188011 hydrochloride (Standard)	Reference Standards DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Autophagy Apoptosis	Cancer
Gemcitabine (hydrochloride) (Standard) is the analytical standard of Gemcitabine (hydrochloride). This product is intended for research and analytical applications. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .

HY-B0083S

Leflunomide-d4	Dihydroorotate Dehydrogenase	Cancer
Leflunomide-d₄ (HWA486-d₄) is the deuterium labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent .

HY-17026R

Gemcitabine (Standard) LY 188011 (Standard)	Reference Standards Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Autophagy Apoptosis	Cancer
Gemcitabine (Standard) is the analytical standard of Gemcitabine. This product is intended for research and analytical applications. Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .

HY-15405R

Teriflunomide (Standard) A77 1726 (Standard)	Drug Metabolite Reference Standards	Inflammation/Immunology
Teriflunomide (Standard) is the analytical standard of Teriflunomide. This product is intended for research and analytical applications. Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits **pyrimidine synthesis** and therefore potently decreases T cell and B cell proliferation.

Cat. No.	Product Name	Type

HY-101400A

Deoxycytidine triphosphate (trisodium) solution (100mM) 1 Publications Verification dCTP (trisodium) solution (100mM); 2′-Deoxycytidine-5′-triphosphate (trisodium) solution (100mM)	Gene Sequencing and Synthesis
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-42045

Pyrimidine-5-boronic acid pinacol ester

Biochemical Assay Reagents

Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. At the same time, it should be noted that it may be a genotoxic impurity (GTIs) .

HY-N0157C

Orotic acid potassium

2 Publications Verification

6-Carboxyuracil potassium; Vitamin B13 potassium

Cell Assay Reagents

Orotic acid potassium (Vitamin B13 potassium) is a precursor of pyrimidine bases and is involved in the synthesis of DNA and RNA. Orotic acid potassium stimulates the growth of animals, plants and microorganisms, participates in carbohydrate metabolism, and is necessary for the growth and life activities of organisms. Orotic acid potassium is a measurement indicator in routine newborn screening for urea cycle abnormalities. Orotic acid potassium can cause hepatic steatosis and hepatomegaly in rats .

HY-101400

Deoxycytidine triphosphate dCTP; 2′-Deoxycytidine-5′-triphosphate	Gene Sequencing and Synthesis
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-107372H

Uridine triphosphate, 100mM Solution, PCR Grade

UTP, 100mM Solution, PCR Grade; Uridine 5'-triphosphate, 100mM Solution, PCR Grade

Gene Sequencing and Synthesis

Uridine triphosphate, 100 mM Solution, PCR Grade (UTP, 100 mM Solution, PCR Grade) A solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate used as a substrate for RNA synthesis or as an energy source in metabolic reactions .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6961

Lapachol 2 Publications Verification	Infection Quinones Structural Classification Classification of Application Fields Tabebuia avellanedae Bignoniaceae Plants Naphthalene Quinones Inflammation/Immunology Disease Research Fields	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-B0083

Leflunomide 10+ Cited Publications HWA486; RS-34821; SU101	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Dihydroorotate Dehydrogenase Endogenous Metabolite Bacterial
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-W002339

3-Hydroxy-2-methylpyridine	Alkaloids Structural Classification other families Classification of Application Fields Leguminosae Source classification Other Diseases Pyridine Alkaloids Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Disease Research Fields	DNA/RNA Synthesis
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

HY-101400A

Deoxycytidine triphosphate (trisodium) solution (100mM) 1 Publications Verification dCTP (trisodium) solution (100mM); 2′-Deoxycytidine-5′-triphosphate (trisodium) solution (100mM)	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-Y1298

Methyl acetylacetate 1 Publications Verification Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases .

HY-B0158

Cytidine 5+ Cited Publications Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms other families Animals Source classification Disease markers Nervous System Disorder Plants Endogenous metabolite	Nucleoside Antimetabolite/Analog Endogenous Metabolite
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-N8060A

Orotidine 5′-monophosphate trisodium Orotidine monophosphate trisodium; Orotidylic acid trisodium	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite DNA/RNA Synthesis
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT) .

HY-N6961R

Lapachol (Standard)	Quinones Structural Classification Tabebuia avellanedae Bignoniaceae Plants Naphthalene Quinones	Reference Standards Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite
Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-101400

Deoxycytidine triphosphate dCTP; 2′-Deoxycytidine-5′-triphosphate	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-B0083R

Leflunomide (Standard) HWA486 (Standard); RS-34821 (Standard); SU101 (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Dihydroorotate Dehydrogenase Endogenous Metabolite Bacterial
Leflunomide (Standard) is the analytical standard of Leflunomide. This product is intended for research and analytical applications. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-90006

5-Fluorouracil Maximum Cited Publications 246 Publications Verification 5-FU	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Nucleoside Antimetabolite/Analog HIV Apoptosis Endogenous Metabolite
5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects **pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV** .

HY-B0158R

Cytidine (Standard) Cytosine β-D-riboside (Standard); Cytosine-1-β-D-ribofuranoside (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms other families Animals Source classification Disease markers Nervous System Disorder Plants Endogenous metabolite	Reference Standards Nucleoside Antimetabolite/Analog Endogenous Metabolite
Cytidine (Standard) is the analytical standard of Cytidine. This product is intended for research and analytical applications. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function . In Vivo:Cytidine decreases glutamate/glutamine levels and induces earlier improvement of depressive symptoms .

HY-131576

Thymidine 5′-diphosphate dTDP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-131576A

Thymidine 5′-diphosphate sodium dTDP sodium	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-90006R

5-Fluorouracil (Standard) 5-FU (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Nucleoside Antimetabolite/Analog HIV Apoptosis Endogenous Metabolite
5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects **pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV** .

HY-D0186

2'-Deoxyuridine 2 Publications Verification	Infection Structural Classification Natural Products Immune System Disorder Microorganisms Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields	Endogenous Metabolite Thymidylate Synthase
2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-D0186R

2'-Deoxyuridine (Standard)	Structural Classification Natural Products Immune System Disorder Microorganisms Source classification Disease markers Endogenous metabolite	Reference Standards Endogenous Metabolite Thymidylate Synthase
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine. This product is intended for research and analytical applications. 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) . In Vitro:The interaction between the 2-deoxyuridine and the column increases the duration of retention of 2-deoxyuridine . Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min . In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain . 2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .

Cat. No.	Product Name	Chemical Structure

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S

Deoxycytidine triphosphate-d14 dilithium
Deoxycytidine triphosphate-d₁₄ (dCTP-d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-d₁₄) dilithium is deuterium labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-B0003S

Gemcitabine-13C,15N2 hydrochloride
Gemcitabine- ¹³C, ¹⁵N₂ (hydrochloride) is the ¹³C and ¹⁵N labeled Gemcitabine hydrochloride . Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .

HY-B0158S

Cytidine-d2
Cytidine-d₂ is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-B0158S6

Cytidine-15N3
Cytidine- ¹⁵N₃ is the ¹⁵N labeled Cytidine . Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-101400S4

Deoxycytidine triphosphate-13C9 dilithium
Deoxycytidine triphosphate- ¹³C₉ (dCTP- ¹³C₉ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉) dilithium is ¹³C-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium

Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S1

Deoxycytidine triphosphate-15N3,d14 dilithium

Deoxycytidine triphosphate- ¹⁵N₃,d₁₄ (dCTP- ¹⁵N₃,d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃,d₁₄) dilithium is deuterium and ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-B0083S1

Leflunomide-13C6
Leflunomide- ¹³C₆ (HWA486- ¹³C₆) is ¹³C labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-B0083S

Leflunomide-d4
Leflunomide-d₄ (HWA486-d₄) is the deuterium labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent .

HY-B0158S5

Cytidine-13C9,15N3
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine . Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-W768207

Cytidine-1',2',3',4',5'-13C5
Cytidine-1',2',3',4',5'- ¹³C₅ is the ¹³C-labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-90006S

5-Fluorouracil-d1
5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-B0158S8

Cytidine-d13
Cytidine-d13 (Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-90006S2

5-Fluorouracil-15N2
5-Fluorouracil- ¹⁵N₂ is the ¹⁵N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-B0158S7

Cytidine-13C9
Cytidine- ¹³C9 (Cytosine β-D-riboside- ¹³C9; Cytosine-1-β-D-ribofuranoside- ¹³C9) is ¹³C labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-90006S3

5-Fluorouracil-13C4,15N2
5-Fluorouracil- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-90006S1

5-Fluorouracil-13C,15N2
5-Fluorouracil- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-W778990

2-Deoxyuridine-1,2,3,4,5-13C5

2-Deoxyuridine-1,2,3,4,5- ¹³C₅ is the ¹³C-labeled 2'-Deoxyuridine (HY-D0186). 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-W013403S

2'-Deoxy-2'-fluorouridine-d2

2'-Deoxy-2'-fluorouridine-d₂ is the deuterium labeled 2'-Deoxy-2'-fluorouridine . 2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .

Cat. No.	Product Name		Classification

HY-152438

6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Alkynes
6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-152980

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleosides and their Analogs
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154046

4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154122

6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154047

6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152986

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine		Nucleosides and their Analogs
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154002

4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleosides and their Analogs
4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154008

6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154005

4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine		Nucleosides and their Analogs
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152977

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleosides and their Analogs
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152990

Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate		Nucleosides and their Analogs
Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152987

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine		Nucleosides and their Analogs
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-101400A

Deoxycytidine triphosphate (trisodium) solution (100mM) 1 Publications Verification dCTP (trisodium) solution (100mM); 2′-Deoxycytidine-5′-triphosphate (trisodium) solution (100mM)		Nucleotides and their Analogs
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-101400

Deoxycytidine triphosphate dCTP; 2′-Deoxycytidine-5′-triphosphate		Nucleotides and their Analogs
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-152685

4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide		Nucleosides and their Analogs
4-Amino-1-(β-D-ribofurano syl)-7H-pyrrolo [2.3-d] pyrimidine-5-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-B0158

Cytidine Maximum Cited Publications 6 Publications Verification Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside		Nucleosides and their Analogs C
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-148165

L-Cytidine		Nucleosides and their Analogs C
L-Cytidine is an L-configurational form of Cytidine (HY-B0158). L-Cytidine is a pyrimidine nucleoside, a component of RNA. Cytidine can control the glial glutamate cycle, affect brain phospholipid metabolism, catecholamine synthesis and mitochondrial function .

HY-154003

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleosides and their Analogs
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152408

2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine		Nucleosides and their Analogs
2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152828

1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine		Nucleosides and their Analogs
1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152410

6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152414

6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152680

4-Amino-5-cyano-1- (β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine		Nucleosides and their Analogs
4-Amino-5-cyano-1- (β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152818

4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine		Nucleosides and their Analogs
4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152398

6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152819

4-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleosides and their Analogs
4-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152718

4-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile		Nucleosides and their Analogs
4-Amino-5-cyano-1-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152438

6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152443

6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine		Nucleosides and their Analogs
6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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