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Results for "

oxidative deamination

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Fluorescent Dye

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109183
    Luvadaxistat

    TAK-831

    		 Xanthine Oxidase Others
    Luvadaxistat (TAK-831) is an orally active, highly selective, potent D-amino acid oxidase (DAAO) inhibitor. Luvadaxistat inhibits oxidative deamination of D-serine via the human recombinant DAAO enzyme with an IC50 of 14 nM. Luvadaxistat significantly increases D-serine levels in the rodent brain, plasma, and cerebrospinal fluid. Luvadaxistat has the potential for schizophrenia research .
    Luvadaxistat
  • HY-P2987
    L-Amino acid oxidase

    		Endogenous Metabolite Metabolic Disease
    L-Amino acid oxidase is a homodimeric proteins containing flavin adenine dinucleotide. L-Amino acid oxidase can catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia .
    L-Amino acid oxidase
  • HY-E70074
    Monoamine oxidase, plasma

    		Monoamine Oxidase Neurological Disease
    Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions .
    Monoamine oxidase, plasma
  • HY-P2768
    Leucine dehydrogenase, Microorganism

    LDH, EC 1.4.1.9

    		 Endogenous Metabolite Metabolic Disease
    Leucine dehydrogenase, Microorganism (EC 1.4.1.9) can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues .
    Leucine dehydrogenase, Microorganism
  • HY-P2911
    Glutamate dehydrogenase (NAD(P))

    GLDH

    		 Mitochondrial Metabolism Others
    Glutamate dehydrogenase NAD(P) (GLDH) can be found in hepatocytes, renal tissue, brain, muscle, and intestinal cells. Glutamate dehydrogenase NAD(P) is often used in biochemical studies. Glutamate dehydrogenase is a mitochondrial enzyme, it catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG) as part of the urea cycle .
    Glutamate dehydrogenase (NAD(P))
  • HY-E70517
    Histamine dehydrogenase, Microorganism

    		Histamine Receptor Others
    Histamine dehydrogenase, Microorganism (EC 1.4.99) is a homodimeric enzyme which catalyzes oxidative deamination of histamine in the presence of electron carrier .
    Histamine dehydrogenase, Microorganism
  • HY-173334
    hMAO-B-IN-11

    		Monoamine Oxidase Interleukin Related TNF Receptor Neurological Disease
    hMAO-B-IN-11 (Compound 12) is a selective and reversible inhibitor of human monoamine oxidase B (hMAO-B) with an IC50 of 0.11 µM. hMAO-B-IN-11 acts through competitive binding to the hMAO-B active site, preventing oxidative deamination of monoamines and reducing hydrogen peroxide production. hMAO-B-IN-11 also inhibits pro-inflammatory mediators (NO, TNF-α, IL-1β) in activated microglia, hMAO-B-IN-11 is promising for research of neurodegenerative diseases like Parkinson’s and Alzheimer’s .
    hMAO-B-IN-11
  • HY-D1619
    Cyanine3 hydrazide dichloride

    		Fluorescent Dye Others
    Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .
    Cyanine3 hydrazide dichloride
  • HY-172285
    Cy3 hydrazide

    		Fluorescent Dye Others
    Cy3 hydrazide is a cyanine dye linker containing hydrazide, which can be used to label aldehydes and ketones. This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins after oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.
    Cy3 hydrazide
  • HY-173336
    MAO-B-IN-42

    		Monoamine Oxidase Neurological Disease
    MAO-B-IN-42 (Compound 4f) is a selective and reversible inhibitor of monoamine oxidase-B (MAO-B) with an IC50 value of 0.184 μM. MAO-B-IN-42 helps maintain the levels of neurotransmitters by blocking the oxidative deamination of monoamines catalyzed by MAO-B. MAO-B-IN-42 is promising for research of Parkinson's disease .
    MAO-B-IN-42
  • HY-N2554
    Osthenol

    Ostenol

    		 Monoamine Oxidase PI3K Akt Apoptosis Infection Neurological Disease Cancer
    Osthenol (Ostenol) is a reversible, selective, competitive inhibitor of hMAO-A (IC50=0.74 μM, Ki=0.26 μM), with antifungal and antibacterial activity. Osthenol inhibits the oxidative deamination of hMAO-A and regulates the metabolism of monoamine neurotransmitters. Osthenol also inhibits the PI3K/AKT signaling pathway to induce apoptosis of colon cancer cells, arrest the cell cycle at the G1 phase, and inhibit cell proliferation. Osthenol is mainly used in the study of neurological diseases and cancer, especially depression-related MAO-A targeted intervention and colon cancer .
    Osthenol

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