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live-cell imaging

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31

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25

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1250
    Mito-TRFS
    1 Publications Verification

    		 Fluorescent Dye Cancer
    Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells .
    Mito-TRFS
  • HY-D1252
    Fast-TRFS
    2 Publications Verification

    		 Fluorescent Dye Others
    Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
    Fast-TRFS
  • HY-136213
    Endoplasmic reticulum dye 1

    		Fluorescent Dye Others
    Endoplasmic reticulum dye 1 is a promising live cell imaging agent for the detection of exocytotic events at the plasma membrane. Endoplasmic reticulum dye 1 shows low cytotoxicity, resistance to photobleaching , which is ideal for imaging either short- or long-time courses .
    Endoplasmic reticulum dye 1
  • HY-D2418
    PS-SCOTfluor-12

    		Fluorescent Dye Metabolic Disease
    PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .
    PS-SCOTfluor-12
  • HY-131027
    Janelia Fluor® 646, Azide

    JF646, Azide

    		 Fluorescent Dye Others
    Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Janelia Fluor® 646, Azide
  • HY-D1251
    TRFS-red

    		Fluorescent Dye Others
    TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells .
    TRFS-red
  • HY-119493
    MSBN

    		Fluorescent Dye Others
    MSBN is a highly selective fluorogenic probe for thiols. MSBN can be used to image thiols in live cells selectively and specifically label protein thiols with a signal to determine various reversible protein thiol modifications .
    MSBN
  • HY-D1265
    EtS-DMAB
    1 Publications Verification

    HClO-green

    		 Fluorescent Dye Others
    EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells .
    EtS-DMAB
  • HY-141646
    MIT-PZR

    		Fluorescent Dye Others
    MIT-PZR is a mitochondria-targeted,? low cytotoxicity fluorescent probe that can be used in live cells and in vivo imaging. Ex / Em = 485 / 705 nm
    MIT-PZR
  • HY-D2416S
    JFX650

    		Fluorescent Dye Others
    JFX650 is a red fluorescent deuterated dye with a maximum excitation emission wavelength of 650/667 nm. JFX650 is suitable for live cell imaging .
    JFX650
  • HY-162161
    Flutax-2

    		Fluorescent Dye Cancer
    Flutax-2 is an active fluorescent derivative of Paclitaxel, binds to αβ-tubulin dimer polymerized. Flutax-2 can be used for imaging microtubules in live cells, isolated cytoskeletons and parasite (Ex/Em=496/526 nm) .
    Flutax-2
  • HY-110251A
    DFHBI-2T

    		DNA Stain Others
    DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells .
    DFHBI-2T
  • HY-D1254
    Trx-red

    NBL-SS perchlorate

    		 Fluorescent Dye Others
    Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .
    Trx-red
  • HY-D1260
    FM-red

    PSH-red

    		 Fluorescent Dye Neurological Disease
    FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .
    FM-red
  • HY-130017
    HKSOX-1r (5/6-mixture)

    		Reactive Oxygen Species (ROS) Others
    HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .
    HKSOX-1r (5/6-mixture)
  • HY-130015
    HKSOX-1 (5/6-mixture)
    2 Publications Verification

    		 Reactive Oxygen Species (ROS) Others
    HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .
    HKSOX-1 (5/6-mixture)
  • HY-118667
    Dehydroergosterol

    		Liposome Others
    Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .
    Dehydroergosterol
  • HY-D1445
    LysoSensor PDMPO
    1 Publications Verification

    		 Fluorescent Dye Metabolic Disease
    PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .
    LysoSensor PDMPO
  • HY-110251
    DFHBI-1T
    10+ Cited Publications

    		 DNA Stain Others
    DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
    DFHBI-1T
  • HY-D2994
    SPY555-BG

    SNAP-MaP555

    		 Fluorescent Dye Others
    SPY555-BG is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .
    SPY555-BG
  • HY-131026
    Janelia Fluor® 635, SE

    JF635, SE; JF635, NHS

    		 Fluorescent Dye Others
    Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 635, SE
  • HY-141511
    Coppersensor 1
    Maximum Cited Publications
    23 Publications Verification

    		 Fluorescent Dye Neurological Disease Cancer
    Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
    Coppersensor 1
  • HY-D0832
    CY5-N3
    1 Publications Verification

    Sulfo-Cyanine5-azide

    		 DNA Stain Fluorescent Dye Infection
    CY5-N3 (Sulfo-Cyanine5-azide) is a Cy5-azide, which is a fluorescent dye (ex/em: 646/662 nm). CY5-N3 is cell membrane permeable and can be used for live cell imaging. CY5-N3 can be used in cell imagine by Click reaction .
    CY5-N3
  • HY-145789
    Difluorocyclooctyne-CH2-benzoic acid

    		Biochemical Assay Reagents Cancer
    Difluorocyclooctyne-CH2-benzoic acid is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis . Difluorocyclooctyne-CH2-benzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Difluorocyclooctyne-CH2-benzoic acid
  • HY-DY1047
    DFHBI-1T (solution)

    		DNA Stain Others
    DFHBI-1T (solution) is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
    Solution Concentration: 20 mM
    DFHBI-1T (solution)
  • HY-145790
    Difluorocyclooctyne-CH2-COOH

    		Biochemical Assay Reagents Cancer
    Difluorocyclooctyne-CH2-COOH is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis . Difluorocyclooctyne-CH2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Difluorocyclooctyne-CH2-COOH
  • HY-131028
    Janelia Fluor® 646 TFA

    JF646 TFA

    		 Fluorescent Dye Others
    Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 646 TFA
  • HY-D1373
    HBC
    2 Publications Verification

    HBC 530

    		 Fluorescent Dye Others
    HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is nonfluorescent in solution, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
    HBC
  • HY-135799
    WH-15

    		Phospholipase Neurological Disease Cancer
    WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells (Ex/Em = ~344/530 nm) .
    WH-15
  • HY-110210
    BODIPY-FL NHS ester

    BODIPY FL,SE

    		 Fluorescent Dye Others
    BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
    BODIPY-FL NHS ester
  • HY-D2317
    HaloFlipper 30

    		Fluorescent Dye Others
    HaloFlipper 30 is a fluorescent probe that covalently reacts with HaloTag fusion proteins to form an ester bond, which allows the probe to be stably attached to membrane structures. HaloFlipper 30 has high specificity, precision and good cell permeability .
    HaloFlipper 30

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