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iodine

" in MedChemExpress (MCE) Product Catalog:

37

Inhibitors & Agonists

3

Fluorescent Dye

5

Biochemical Assay Reagents

1

Inhibitory Antibodies

2

Natural
Products

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W441271

    Ligands for E3 Ligase Cancer
    Deoxy-thalidomide-5-iodine is a Thalidomide analog that can be useful in PROTAC research.
    Deoxy-thalidomide-5-iodine
  • HY-B2234

    iodopovidone

    Bacterial Infection
    Povidone iodine (iodopovidone) displays excellent antibacterial activity which can against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively.
    Povidone iodine
  • HY-D1054

    Cyanine2 (iodine)

    Fluorescent Dye Others
    Cy2 iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
    Cy2 (iodine)
  • HY-D0826

    Cyanine2 Succinimidyl Ester (iodine)

    Fluorescent Dye Others
    Cy2-SE iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
    Cy2-SE (iodine)
  • HY-108775A

    Sodium hyposulfite (99%, water≤1.0%)

    Biochemical Assay Reagents Others
    Sodium thiosulfate (99%, water≤1.0%) (Sodium hyposulfite (99%, water≤1.0%)) can be used for the titrimetric determination of elemental iodine and for the detection of trace cysteine. Sodium thiosulfate (99%, water≤1.0%) is a kind of biological materials or organic compounds that are widely used in life science research .
    Sodium thiosulfate (99%, water≤1.0%)
  • HY-130982

    E3 Ligase Ligand-Linker Conjugates Cancer
    Lenalidomide-PEG3-iodine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a 3-unit PEG linker. Lenalidomide-PEG3-iodine can be used in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM .
    Lenalidomide-PEG3-iodine
  • HY-169395

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-CO-PEG-C2-iodine is an E3 ligase (VHL) ligand-linker conjugate, and can be used for synthesis of PROTACs, such as PROTAC FAK degrader 1 (HY-119932)
    (S,R,S)-AHPC-CO-PEG-C2-iodine
  • HY-N0224A

    (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone

    Influenza Virus Metabolic Disease
    Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .
    Goitrin
  • HY-133846

    Thyroid Hormone Receptor Cancer
    Iodothiouracil exhibits high selectivity for melanoma, remains stable in the melanin in melanoma cells, and localizes remote secondary metastases of melanoma. Iodothiouracil can be used for melanoma imaging when labeled with iodine-123, and can be used for radiation therapy when labeled with iodine-131 .
    Iodothiouracil
  • HY-W348170

    Biochemical Assay Reagents Others
    tert-Butyl((5-iodopentyl)oxy)dimethylsilane is a silane compound with a terminal iodine group. The trimethylsilane is commonly used for surface modifications. The iodine (I) is a very good leaving group for nucleophilic substitution reactions.
    tert-Butyl((5-iodopentyl)oxy)dimethylsilane
  • HY-B1426
    Iodixanol
    3 Publications Verification

    Biochemical Assay Reagents Cancer
    Iodixanol is an iodine-containing non-ionic radiocontrast agent .
    Iodixanol
  • HY-W053842

    Biochemical Assay Reagents Others
    tert-Butyl 3-iodopropylcarbamate is a compound with a t-butyl and a terminal iodine. The iodine (I) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl 3-iodopropylcarbamate
  • HY-W248726

    Biochemical Assay Reagents Others
    tert-Butyl (6-iodohexyl)carbamate is a six carbon linker containing an iodine group and a t-butyl ester. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The t-butyl ester groups can be deprotected under acidic conditions.
    tert-Butyl (6-iodohexyl)carbamate
  • HY-B1362
    Iopromide
    2 Publications Verification

    Biochemical Assay Reagents Cardiovascular Disease
    Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.
    Iopromide
  • HY-W092078

    Biochemical Assay Reagents Others
    tert-Butyl (4-iodobutyl)carbamate is a four carbon linker containing a Boc-protected amino group and an iodine group. The Boc group can be deprotected under mild acidic conditions to form the free amine. Iodine (I) is a very good leaving group for nucleophilic substitution reactions.
    tert-Butyl (4-iodobutyl)carbamate
  • HY-W460133

    Biochemical Assay Reagents Others
    tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate is a PEG linker containing a Boc protected amine and an iodine group. The protected amine can be deprotected under mild acidic conditions. Iodine (I) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
    tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate
  • HY-W586331

    Ligands for E3 Ligase Cancer
    Thalidomide-iodo is an iodinated E3 ligase activator. Thalidomide-iodo can be used for further derivitization by substitution of iodine.
    Thalidomide-iodo
  • HY-B1362S

    Isotope-Labeled Compounds Cardiovascular Disease
    Iopromide-d3 is the deuterium labeled Iopromide. Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.
    Iopromide-d3
  • HY-B1362R

    Biochemical Assay Reagents Cardiovascular Disease
    Iopromide (Standard) is the analytical standard of Iopromide. This product is intended for research and analytical applications. Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.
    Iopromide (Standard)
  • HY-B1620

    PVP K30; Polyvidone K30; Povidone K30

    Biochemical Assay Reagents Infection
    Polyvinylpyrrolidone K30 is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.
    Polyvinylpyrrolidone K30
  • HY-W076313

    Ligands for E3 Ligase Cancer
    2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione is a derivative of Thalidomide with an iodine atom on the benzyl ring
    2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione
  • HY-B1620I

    PVP K120; Polyvidone K120; Povidone K120

    Biochemical Assay Reagents Infection
    Polyvinylpyrrolidone K120 is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds .
    Polyvinylpyrrolidone K120
  • HY-149132

    DDA

    LXR Cancer
    Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase .
    Dendrogenin A
  • HY-131556

    p-Iodoamphetamine hydrochloride

    5-HT Receptor Neurological Disease
    4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. 4-Iodoamphetamine hydrochloride selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes.
    4-Iodoamphetamine hydrochloride
  • HY-B1796

    Fungal Infection
    Thymol iodide is a compound of Iodide and Thymol. Thymol iodide acts as a substitute for iodoform . Thymol iodide is an iodine derivative of Thymol (a phenol derived from thyme oil), which is mostly used as mild antiseptic and fungicide .
    Thymol iodide
  • HY-W075603

    2,6-Diiodo-Pyrromethene 546; 2,6-Diiodo-BDP 493/503 lipid stain

    Fluorescent Dye Others
    2,6-Diiodo-BODIPY 493/503 is an F-Bodipy fluorescent dye with diiodo substitution at the (pyrrole) 2,6 position. 2,6-Diiodo-BODIPY 493/503 has a pyrrole iodine substituent that turns it red .
    2,6-Diiodo-BODIPY 493/503
  • HY-W251756

    Biochemical Assay Reagents Others
    3-(2-Iodoethoxy)prop-1-yne is a crosslinker that can be used in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage with azides. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions.
    3-(2-Iodoethoxy)prop-1-yne
  • HY-114918

    TSH Receptor Endocrinology
    MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice .
    MS438
  • HY-P99566

    ST2146

    Transmembrane Glycoprotein Cancer
    Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunoresearch (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach .
    Tenatumomab
  • HY-114994

    TSH Receptor Endocrinology
    MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10 -8 M. MS437 shows potent activation of G, Gαq and 12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions .
    MS437
  • HY-117953

    Prostaglandin Receptor Endocrinology
    RU 59063 is an N-substituted arylthiohydantoin compound with antiandrogenic activity and high relative binding affinity for the rat androgen receptor. RU 59063 is a nonsteroidal androgen receptor that functions as a radioactive AR radioprobe (Ki: 0.71 nM, rAR) when its trifluoromethyl group is replaced by a similar hydrophobic iodine atom .
    RU 59063
  • HY-107903

    Thyroglobulin from bovine

    Biochemical Assay Reagents Cancer
    Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle .
    Thyroglobulin
  • HY-W403732

    Biochemical Assay Reagents Others
    8-Iodooct-7-yn-1-ol comprises an iodo-propargyl group attached to a 6-carbon tail with a terminal hydroxyl group. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
    8-Iodooct-7-yn-1-ol
  • HY-W400574

    6-Iodo-1-Hexanol

    Biochemical Assay Reagents Others
    6-Iodohexan-1-ol (6-Iodo-1-Hexanol) comprises an Iodo group attached to a 6-carbon tail with a terminal hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions.
    6-Iodohexan-1-ol
  • HY-B1620H

    PVP K90; Polyvidone K90; Povidone K90

    Biochemical Assay Reagents Infection
    Polyvinylpyrrolidone K90 can be used to prepare drug delivery systems, such as electrospun nanofibrous membranes. Polyvinylpyrrolidone K90 is widely used in human and veterinary medicine as an effective wound healing promoter and disinfectant when combined with iodine and other compounds. In addition, Polyvinylpyrrolidone K90 is also used to stabilize nanosuspensions, interact with the surface of drug crystals, and remain bound to the surface after drying .
    Polyvinylpyrrolidone K90
  • HY-155446

    Others Inflammation/Immunology Cancer
    di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients .
    di-DTPA-LTL
  • HY-14998

    MK 185

    β-catenin PPAR Wnt Endocrinology
    Halofenate, structurally akin to clofibrate, was evaluated in hypertriglyceridemic patients over 6-week periods in a controlled, double-blind crossover trial. It effectively reduced serum triglycerides by 50%, with minimal impact on serum cholesterol levels. Additionally, it lowered serum uric acid by 30% and exhibited uricosuric effects independent of glomerular filtration rate. Halofenate was associated with a significant increase in plasma thyroxine (T4), accompanied by a decrease in protein-bound iodine and T4 by column. In vitro studies confirmed its ability to displace T4 from thyroid-binding proteins, suggesting a thyroxine-displacing effect, which could influence thyroid function in vivo .
    Halofenate

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