hydroxycarboxylic acid receptor 1

By Targets:	Hydroxycarboxylic Acid Receptor (HCAR) (2) Endogenous Metabolite (5) Reference Standards (2) Tyrosinase (2)
By Research Areas:	Cancer (3) Inflammation/Immunology (3) Metabolic Disease (5)

Targets Recommended: Hydroxycarboxylic Acid Receptor (HCAR) Amino acid Transporter Amino Acid Derivatives Amino Acid Decarboxylase Amino Acid Oxidase Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2227

Lactate 25+ Cited Publications Lactic acid	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-B2227R

Lactate (Standard) Lactic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
Lactate (Standard) is the analytical standard of Lactate. This product is intended for research and analytical applications. Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-B2227D

Calcium 2-hydroxypropanoate pentahydrate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
Calcium 2-hydroxypropanoate (pentahydrate) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Calcium 2-hydroxypropanoate (pentahydrate) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Calcium 2-hydroxypropanoate (pentahydrate) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-W015560

3,5-Dihydroxybenzoic acid	Endogenous Metabolite Tyrosinase Hydroxycarboxylic Acid Receptor (HCAR)	Metabolic Disease
3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses. 3,5-Dihydroxybenzoic acid is the agonist for **hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) that inhibits lipolysis in adipocytes. 3,5-Dihydroxybenzoic acid is the competitive inhibitor for tyrosine phenol-lyase (TPL), exhibits an affinity of K_i**=25.7 μM. 3,5-Dihydroxybenzoic acid is orally active .

HY-W015560R

3,5-Dihydroxybenzoic acid (Standard)	Reference Standards Endogenous Metabolite Tyrosinase Hydroxycarboxylic Acid Receptor (HCAR)	Metabolic Disease
3,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 3,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses. 3,5-Dihydroxybenzoic acid is the agonist for **hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) that inhibits lipolysis in adipocytes. 3,5-Dihydroxybenzoic acid is the competitive inhibitor for tyrosine phenol-lyase (TPL), exhibits an affinity of K_i**=25.7 μM. 3,5-Dihydroxybenzoic acid is orally active .

Cat. No.	Product Name	Type

HY-B2227D

Calcium 2-hydroxypropanoate pentahydrate	Cell Assay Reagents
Calcium 2-hydroxypropanoate (pentahydrate) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Calcium 2-hydroxypropanoate (pentahydrate) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Calcium 2-hydroxypropanoate (pentahydrate) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

Calcium 2-hydroxypropanoate pentahydrate

Cell Assay Reagents

Calcium 2-hydroxypropanoate (pentahydrate) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Calcium 2-hydroxypropanoate (pentahydrate) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Calcium 2-hydroxypropanoate (pentahydrate) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B2227

Lactate 25+ Cited Publications Lactic acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-B2227R

Lactate (Standard) Lactic acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Lactate (Standard) is the analytical standard of Lactate. This product is intended for research and analytical applications. Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-W015560

3,5-Dihydroxybenzoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Tyrosinase Hydroxycarboxylic Acid Receptor (HCAR)
3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses. 3,5-Dihydroxybenzoic acid is the agonist for **hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) that inhibits lipolysis in adipocytes. 3,5-Dihydroxybenzoic acid is the competitive inhibitor for tyrosine phenol-lyase (TPL), exhibits an affinity of K_i**=25.7 μM. 3,5-Dihydroxybenzoic acid is orally active .

HY-W015560R

3,5-Dihydroxybenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Endogenous metabolite	Reference Standards Endogenous Metabolite Tyrosinase Hydroxycarboxylic Acid Receptor (HCAR)
3,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 3,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses. 3,5-Dihydroxybenzoic acid is the agonist for **hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) that inhibits lipolysis in adipocytes. 3,5-Dihydroxybenzoic acid is the competitive inhibitor for tyrosine phenol-lyase (TPL), exhibits an affinity of K_i**=25.7 μM. 3,5-Dihydroxybenzoic acid is orally active .

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hydroxycarboxylic acid receptor 1

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