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  3. Lactate (sodium) (60% in water)

Lactate (sodium) (60% in water)  (Synonyms: Lactic acid sodium)

Cat. No.: HY-B2227B Purity: ≥98.0%
Handling Instructions Technical Support

Lactate (60% in water) (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate sodium (60% in water) is an organic salt that is mainly used as a buffer and pH adjuster for injection solutions. Lactate sodium (60% in water) can be metabolized by the body into sodium bicarbonate, which in turn acts to increase the pH of the blood. Lactate sodium (60% in water) is used to improve metabolic acidosis and hypovolemic states. In terms of pharmaceutical preparations, Lactate sodium (60% in water) is often used in combination with sodium chloride, glucose, etc. to form normal saline or compound liquid intravenous injection. Lactate sodium (60% in water) also has antimicrobial activity, which can be used as a food preservative.

For research use only. We do not sell to patients.

CAS No. : 72-17-3

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Solution
10 mM * 1 mL in Water In-stock
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Customer Review

Based on 33 publication(s) in Google Scholar

Other Forms of Lactate (sodium) (60% in water):

Top Publications Citing Use of Products

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Feb 15:81:103553.  [Abstract]

    Immunoblot and quantification analyses of NFS1 in HCC cells incubated with 0, 5, or 10 mM lactate after being subjected to either a 47 °C or 37 °C water bath.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144.  [Abstract]

    Lactate (25 mM) significantly increases the mRNA and protein expression of FBXO33.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144.  [Abstract]

    Co-IP detected the effect of lactate on YY1 protein lactylation modification.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Mar 20;16(1):193.  [Abstract]

    Lactate sodium (5-15 mM; 24 h) ​​results​​ in increased H4K12la (red) levels in CCSCs compared to the control group.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2024 Mar 5;43(1):68.  [Abstract]

    Lactate sodium increases IGF-1R levels in PI-resistant KAS-6/1 and U266 cells.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Res. 2023 Sep;33(9):679-698.  [Abstract]

    Lactate (NALA) (300 mM; 24 h) significantly upregulates α-MHC K1897 lactylation in H9c2 cells.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: J Ginseng Res. 2023 Dec 27.

    The expression level of METTL3, YTHDF1, YTHDF2, and YTHDC1 in NB4-R1 and NB4-R2 cells treated with 20 μM oxamate or 20 μM lactate or 1 μM ATRA for 48 h was detected via qRT-PCR.
    • Biological Activity

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    • Customer Review

    Description

    Lactate (60% in water) (Lactic acid) sodium is the product of glycogenolysis and glycolysis[1]. Lactate sodium (60% in water) is an organic salt that is mainly used as a buffer and pH adjuster for injection solutions. Lactate sodium (60% in water) can be metabolized by the body into sodium bicarbonate, which in turn acts to increase the pH of the blood. Lactate sodium (60% in water) is used to improve metabolic acidosis and hypovolemic states. In terms of pharmaceutical preparations, Lactate sodium (60% in water) is often used in combination with sodium chloride, glucose, etc. to form normal saline or compound liquid intravenous injection[2][3][4][5]. Lactate sodium (60% in water) also has antimicrobial activity, which can be used as a food preservative[6].

    In Vitro

    Hypertonic Lactate sodium solution improved cognitive function in rats with traumatic brain injury (TBI). Hyperlactate sodium solution also decreased intracranial pressure (ICP) and increased cerebral blood flow by arteriole dilation[2][3].
    Lactate sodium inhibits the proliferation of various decrepit microorganisms, including aerobic and chillophilic bacteria, pseudomonas, lactic acid bacteria and Enterobacteriaceae[6].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    In Vivo

    The pH of the working solution needs to be adjusted to around 7.4 before administration to animals.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Clinical Trial
    Molecular Weight

    112.06

    Formula

    C3H5NaO3

    CAS No.
    Appearance

    Liquid

    Color

    Colorless to light yellow

    SMILES

    [Na].O=C(O)C(O)C

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Solution, -20°C, 2 years

    Purity & Documentation

    Purity: ≥98.0%

    References
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    Lactate (sodium) (60% in water) Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Lactate (sodium) (60% in water)
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