growth promotion

By Targets:	EGFR (1) TGF-β Receptor (1) Bacterial (1) Bcl-2 Family (1) CD74 (1) Collagen (1) Cytochrome P450 (1) Fungal (1) Leukotriene Receptor (1) Mitosis (1) mTOR (1) Phytohormone (1) PKC (2) Succinate Dehydrogenase (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Endocrinology (1) Infection (2) Inflammation/Immunology (1) Metabolic Disease (2)

Targets Recommended: FGFR GHR VEGFR TGF-beta/Smad PDGFR TGF-β Receptor GHSR EGFR IGF-1R Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5258

Oligopeptide-41	EGFR	Metabolic Disease
Oligopeptide-41 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-P5239

Myristoyl pentapeptide-4	Collagen	Others
Myristoyl pentapeptide-4 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-W753375

Fluindapyr	Fungal Succinate Dehydrogenase	Infection
Fluindapyr is a broad-spectrum pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor (SDHIs) with broad bactericidal spectrum and good efficacy. Fluopimomide is effective against M. incognita in vitro and application of fuopimomide shows some growth promotion effect in cucumber .

HY-P99590

Sotatercept ACE-011	TGF-β Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions .

HY-150084

(±)14,15-Epoxyeicosatrienoic acid (±)14(15)-EET	Cytochrome P450 Mitosis	Cancer
(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth .

HY-108963

LY 170198	PKC Leukotriene Receptor	Cancer
LY 170198 is a protein kinase C inhibitor and a LTD₄ antagonist. LY 170198 is promising for research of tumor promotion, oncogene activation, protein phosphorylation, feedback mechanisms in signal transduction and cellular responses to growth factors .

HY-W008769

Ethychlozate	Others	Endocrinology
Ethychlozate is a plant growth regulator on the promotion of flowering in citrus .

HY-N15018

20-Deoxynarasin	Bacterial	Infection
20-Deoxynarasin has anti-Gram-positive bacteria, mycoplasma, coccidia and virus activity, and has effect on growth promotion .

HY-P3842

Protein Kinase C (661-671)	PKC	Cancer
Protein Kinase C (661-671) is a fragment peptide of β1 subspecies of protein kinase C (PKC). PKC plays a role in cellular growth control and tumor promotion .

HY-129613

Rhizonin A	Phytohormone	Others
Rhizonin A is a cyclic heptapeptide that can be isolated from Rhizopus micro-sporus van Tieghem and can promote plant growth .

HY-P5243

Copper tripeptide-3 AHK-Cu	Others Bcl-2 Family	Others
Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect. Copper tripeptide-3 increases dermal cell proliferation and viability while increasing the deposition of collagen to renew the extracellular matrix. Copper tripeptide-3 stimulates the elongation of human hair follicles and proliferation of dermal papilla cells .

HY-P99731

Milatuzumab 3 Publications Verification hLL1; MEDI-115	CD74	Cancer
Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death .

HY-W348485

WRX606	mTOR	Cancer
WRX606 is an orally active nonrapalog inhibitor for mTOR complex 1 (mTORC1M). WRX606 inhibits the phosphorylation of mTORC1 substrate S6 kinase 1 (S6K1) (IC₅₀ = 10 nM) and eukaryotic translation initiation factor 4E binding protein (p-4E-BP1) (IC₅₀ = 0.27 μM) in MCF-7 cells. WRX606 suppresses tumor growth in mice without promotion of metastasis. WRX606 can be studied in research as an antitumor agent .

Cat. No.	Product Name	Target	Research Area

HY-P5258

Oligopeptide-41	EGFR	Metabolic Disease
Oligopeptide-41 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-P5239

Myristoyl pentapeptide-4	Collagen	Others
Myristoyl pentapeptide-4 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-P5243

Copper tripeptide-3 AHK-Cu	Peptides Bcl-2 Family	Others
Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect. Copper tripeptide-3 increases dermal cell proliferation and viability while increasing the deposition of collagen to renew the extracellular matrix. Copper tripeptide-3 stimulates the elongation of human hair follicles and proliferation of dermal papilla cells .

HY-P5260

Oligopeptide-74	Peptides	Metabolic Disease
Oligopeptide-74 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-P3842

Protein Kinase C (661-671)	PKC	Cancer
Protein Kinase C (661-671) is a fragment peptide of β1 subspecies of protein kinase C (PKC). PKC plays a role in cellular growth control and tumor promotion .

HY-129613

Rhizonin A	Phytohormone	Others
Rhizonin A is a cyclic heptapeptide that can be isolated from Rhizopus micro-sporus van Tieghem and can promote plant growth .

Cat. No.	Product Name	Target	Research Area

HY-P99590

Sotatercept ACE-011	TGF-β Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions .

HY-P99731

Milatuzumab 3 Publications Verification hLL1; MEDI-115	CD74	Cancer
Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-150084

(±)14,15-Epoxyeicosatrienoic acid (±)14(15)-EET	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Cytochrome P450 Mitosis
(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth .

HY-N15018

20-Deoxynarasin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
20-Deoxynarasin has anti-Gram-positive bacteria, mycoplasma, coccidia and virus activity, and has effect on growth promotion .

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growth promotion

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