Search Result
Results for "
folate receptors
" in MedChemExpress (MCE) Product Catalog:
55
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-13728
-
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ZD 9331; BGC9331
|
Thymidylate Synthase
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Cancer
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Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
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- HY-10822A
-
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BGC 945 trisodium; ONX 0801 trisodium; CB 300945 trisodium
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Thymidylate Synthase
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Cancer
|
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Idetrexed (ONX 0801) trisodium is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed trisodium can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
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-
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- HY-147699
-
|
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Antifolate
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Cancer
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FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells .
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-
-
- HY-P11024
-
|
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Folate Receptor (FR)
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Cancer
|
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NVP-EVS459 is a Folate Receptor (FR)-targeting radioconjugate. NVP-EVS459 labeled with 177Lu can be used for tumor diagnosis and treatment research .
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-
-
- HY-167412
-
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Biochemical Assay Reagents
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Others
|
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PLLA5000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG2000-FOL can be used in drug delivery research .
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-
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- HY-167415
-
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Biochemical Assay Reagents
|
Others
|
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PLLA10000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG5000-FOL can be used in drug delivery research .
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-
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- HY-167413
-
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Biochemical Assay Reagents
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Others
|
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PLLA20000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG5000-FOL can be used in drug delivery research .
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-
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- HY-167411
-
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Biochemical Assay Reagents
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Others
|
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PLLA5000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG5000-FOL can be used in drug delivery research .
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-
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- HY-167416
-
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Biochemical Assay Reagents
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Others
|
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PLLA10000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG2000-FOL can be used in drug delivery research .
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-
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- HY-167414
-
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Biochemical Assay Reagents
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Others
|
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PLLA20000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG2000-FOL can be used in drug delivery research .
|
-
-
- HY-P10501
-
|
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Antifolate
|
Cancer
|
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FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment .
|
-
-
- HY-P10501A
-
|
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Antifolate
|
Cancer
|
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FRα-targeting peptide C7 TFA is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 TFA can be used in the research of tumor diagnosis and treatment .
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-
-
- HY-P99612
-
|
MORAb-202
|
Antibody-Drug Conjugates (ADCs)
|
Cancer
|
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Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.
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-
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- HY-172935
-
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Antifolate
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Cancer
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FR-β ligand 1 (III), a folate receptor-targeting ligand, possesses antitumor activity, high selectivity, and stronger affinity for folate receptor .
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-
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- HY-115873
-
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PROTACs
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Cancer
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Folate-MS432, a PROTAC, is capable of degrading MEKs in a folate receptor-dependent manner in cancer cells.
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-
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- HY-W440888B
-
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Biochemical Assay Reagents
|
Others
|
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DSPE-PEG-Folate (MW 3400) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
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- HY-W440888A
-
|
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Biochemical Assay Reagents
|
Others
|
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DSPE-PEG-Folate (MW 1000) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
-
- HY-W440888C
-
|
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Biochemical Assay Reagents
|
Others
|
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DSPE-PEG-Folate (MW 5000) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
-
- HY-144009
-
|
|
Liposome
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Cancer
|
|
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
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-
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- HY-13615
-
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EC-17
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Fluorescent Dye
Folate Receptor (FR)
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Cancer
|
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Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .
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-
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- HY-W440888
-
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DSPE-PEG(2000) folate
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Liposome
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Others
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DSPE-PEG-Folate, MW 2000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 2000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 2000 form micelles/lipid bilayer and can be used to targeted drug delivery system research.
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-
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- HY-W440890
-
|
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Liposome
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Cancer
|
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DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .
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-
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- HY-W1123932
-
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mPEG-folate (MW 1000)
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Biochemical Assay Reagents
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Others
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mPEG-FA (MW 1000) (mPEG-Folate (MW 1000)) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-W1123932B
-
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mPEG-folate (MW 5000)
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Biochemical Assay Reagents
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Others
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mPEG-FA (MW 5000) (mPEG-Folate (MW 5000)) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-W1123932A
-
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mPEG-folate (MW 2000)
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Biochemical Assay Reagents
|
Others
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mPEG-FA (MW 2000) (mPEG-Folate (MW 2000)) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-128937
-
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Liposome
Folate Receptor (FR)
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Cancer
|
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EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy .
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-
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- HY-174966D
-
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BOC-NH-PEG-folate (MW 3400)
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Biochemical Assay Reagents
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Others
|
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BOC-NH-PEG-FA (MW 3400) (BOC-NH-PEG-Folate (MW 3400)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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- HY-174966E
-
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BOC-NH-PEG-folate (MW 5000)
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Biochemical Assay Reagents
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Others
|
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BOC-NH-PEG-FA (MW 5000) (BOC-NH-PEG-Folate (MW 5000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-174966C
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BOC-NH-PEG-folate (MW 2000)
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Biochemical Assay Reagents
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Others
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BOC-NH-PEG-FA (MW 2000) (BOC-NH-PEG-Folate (MW 2000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-174966B
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BOC-NH-PEG-folate (MW 1000)
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Biochemical Assay Reagents
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Others
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BOC-NH-PEG-FA (MW 1000) (BOC-NH-PEG-Folate (MW 1000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-174966
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BOC-NH-PEG-folate (MW 400)
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Biochemical Assay Reagents
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Others
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BOC-NH-PEG-FA (MW 400) (BOC-NH-PEG-Folate (MW 400)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-174966H
-
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BOC-NH-PEG-folate (MW 10000)
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Biochemical Assay Reagents
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Others
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BOC-NH-PEG-FA (MW 10000) (BOC-NH-PEG-Folate (MW 10000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-174966A
-
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BOC-NH-PEG-folate (MW 600)
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Biochemical Assay Reagents
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Others
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BOC-NH-PEG-FA (MW 600) (BOC-NH-PEG-Folate (MW 600)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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-
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- HY-155882
-
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mPEG-NH2 (MW 750)
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Biochemical Assay Reagents
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Cancer
|
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mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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-
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- HY-155880
-
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mPEG-NH2 (MW 350)
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Biochemical Assay Reagents
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Cancer
|
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mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-155883
-
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mPEG-NH2 (MW 3400)
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Biochemical Assay Reagents
|
Cancer
|
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mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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-
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- HY-155881
-
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mPEG-NH2 (MW 550)
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Biochemical Assay Reagents
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Cancer
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mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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-
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- HY-155884
-
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mPEG-NH2 (MW 4000)
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Biochemical Assay Reagents
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Cancer
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mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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-
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- HY-P99225
-
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M9346A
|
Antifolate
ADC Antibody
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Cancer
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Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
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- HY-128939
-
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Antifolate
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Cancer
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EC0488 is used to synthesize EC0531 with folate receptor (FR)-specific and anti-tumor activities .
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-
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- HY-W1123945D
-
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8-Arm-PEG-folate (MW 3400)
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Biochemical Assay Reagents
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Others
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8-Arm-PEG-FA (MW 3400) (8-Arm-PEG-folate (MW 3400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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- HY-W1123945C
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8-Arm-PEG-folate (MW 2000)
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Biochemical Assay Reagents
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Others
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8-Arm-PEG-FA (MW 2000) (8-Arm-PEG-folate (MW 2000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
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- HY-W1123921E
-
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4-Arm-PEG-folate (MW 5000)
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Biochemical Assay Reagents
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Others
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4-Arm-PEG-FA (MW 5000) (4-Arm-PEG-folate (MW 5000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
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- HY-W1123945
-
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8-Arm-PEG-folate (MW 400)
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Biochemical Assay Reagents
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Others
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8-Arm-PEG-FA (MW 400) (8-Arm-PEG-folate (MW 400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
-
- HY-W1123921H
-
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4-Arm-PEG-folate (MW 10000)
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Biochemical Assay Reagents
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Others
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4-Arm-PEG-FA (MW 10000) (4-Arm-PEG-folate (MW 10000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
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- HY-W1123921
-
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4-Arm-PEG-folate (MW 400)
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Biochemical Assay Reagents
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Others
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4-Arm-PEG-FA (MW 400) (4-Arm-PEG-folate (MW 400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
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- HY-W1123921A
-
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4-Arm-PEG-folate (MW 600)
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Biochemical Assay Reagents
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Others
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4-Arm-PEG-FA (MW 600) (4-Arm-PEG-folate (MW 600)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
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- HY-W1123945E
-
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8-Arm-PEG-folate (MW 5000)
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Biochemical Assay Reagents
|
Others
|
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8-Arm-PEG-FA (MW 5000) (8-Arm-PEG-folate (MW 5000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
-
- HY-W1123945A
-
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8-Arm-PEG-folate (MW 600)
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Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-FA (MW 600) (8-Arm-PEG-folate (MW 600)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
-
- HY-W1123921C
-
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4-Arm-PEG-folate (MW 2000)
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Biochemical Assay Reagents
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Others
|
|
4-Arm-PEG-FA (MW 2000) (4-Arm-PEG-folate (MW 2000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
- HY-W1123945H
-
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8-Arm-PEG-folate (MW 10000)
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Biochemical Assay Reagents
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Others
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8-Arm-PEG-FA (MW 10000) (8-Arm-PEG-folate (MW 10000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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- HY-W1123945B
-
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8-Arm-PEG-folate (MW 1000)
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Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-FA (MW 1000) (8-Arm-PEG-folate (MW 1000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
- HY-W1123921B
-
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4-Arm-PEG-folate (MW 1000)
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Biochemical Assay Reagents
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Others
|
|
4-Arm-PEG-FA (MW 1000) (4-Arm-PEG-folate (MW 1000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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-
- HY-P99225A
-
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M9346A (powder)
|
Antifolate
ADC Antibody
|
Cancer
|
|
Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
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- HY-W1123921D
-
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4-Arm-PEG-folate (MW 3400)
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Biochemical Assay Reagents
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Others
|
|
4-Arm-PEG-FA (MW 3400) (4-Arm-PEG-folate (MW 3400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
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- HY-129880
-
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Deacetylvinblastine hydrazide; DAVLBH
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Microtubule/Tubulin
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Cancer
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Desacetylvinblastine hydrazide (Deacetylvinblastine hydrazide; DAVLBH) is an active component of EC145, a folate-targeted drug conjugate. Desacetylvinblastine hydrazide interferes with the formation of the mitotic spindle, and thus inhibits cell division and leads to cell death. Desacetylvinblastine hydrazide exhibits antitumor activity against folate receptor (FR)-positive tumor .
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- HY-W888710C
-
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folate-PEG-COOH (MW 1000)
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Biochemical Assay Reagents
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Others
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FA-PEG-COOH (MW 1000) (Folate-PEG-COOH (MW 1000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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- HY-W888710A
-
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folate-PEG-COOH (MW 400)
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Biochemical Assay Reagents
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Others
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FA-PEG-COOH (MW 400) (Folate-PEG-COOH (MW 400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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- HY-W888710D
-
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folate-PEG-COOH (MW 2000)
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Biochemical Assay Reagents
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Others
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FA-PEG-COOH (MW 2000) (Folate-PEG-COOH (MW 2000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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- HY-W888710E
-
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folate-PEG-COOH (MW 3400)
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Biochemical Assay Reagents
|
Others
|
|
FA-PEG-COOH (MW 3400) (Folate-PEG-COOH (MW 3400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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- HY-W888710B
-
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folate-PEG-COOH (MW 600)
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Biochemical Assay Reagents
|
Others
|
|
FA-PEG-COOH (MW 600) (Folate-PEG-COOH (MW 600)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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- HY-W888710H
-
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folate-PEG-COOH (MW 5000)
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Biochemical Assay Reagents
|
Others
|
|
FA-PEG-COOH (MW 5000) (Folate-PEG-COOH (MW 5000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710I
-
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folate-PEG-COOH (MW 10000)
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Biochemical Assay Reagents
|
Others
|
|
FA-PEG-COOH (MW 10000) (Folate-PEG-COOH (MW 10000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-174960E
-
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6-Arm-PEG-folate (MW 5000)
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Biochemical Assay Reagents
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Others
|
|
6-Arm-PEG-FA (MW 5000) (6-Arm-PEG-Folate (MW 5000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960B
-
|
6-Arm-PEG-folate (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-FA (MW 1000) (6-Arm-PEG-Folate (MW 1000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960D
-
|
6-Arm-PEG-folate (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-FA (MW 3400) (6-Arm-PEG-Folate (MW 3400)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960A
-
|
6-Arm-PEG-folate (MW 600)
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-FA (MW 600) (6-Arm-PEG-Folate (MW 600)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960C
-
|
6-Arm-PEG-folate (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-FA (MW 2000) (6-Arm-PEG-Folate (MW 2000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960
-
|
6-Arm-PEG-folate (MW 400)
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-FA (MW 400) (6-Arm-PEG-Folate (MW 400)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960H
-
|
6-Arm-PEG-folate (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-FA (MW 10000) (6-Arm-PEG-Folate (MW 10000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-W115607
-
|
Poly(ethylene glycol)-bis-amine (MW 8000)
|
Biochemical Assay Reagents
|
Cancer
|
|
PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W591632
-
|
Poly(ethylene glycol)-bis-amine (MW 1000)
|
Biochemical Assay Reagents
|
Cancer
|
|
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-114306
-
|
|
Antifolate
|
Cancer
|
|
EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor . Small molecule-agent conjugate (SMDC) .
|
-
- HY-132258A
-
|
IMGN853 (solution)
|
Antibody-Drug Conjugates (ADCs)
Antifolate
|
Cancer
|
|
Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage .
|
-
- HY-D2523
-
|
|
Folate Receptor (FR)
Fluorescent Dye
|
|
|
Cy3-PEG-FA (MW 2000) is a fluorescent folate-PEG derivative with excitation/emission wavelengths of ~550 nm/~570 nm. Cy3-PEG-FA (MW 2000) can be readily traced by its intense red fluorescent signal. Cy3-PEG-FA (MW 2000) can be used for cell imaging, folate receptor targeting and detection.
|
-
- HY-10822
-
|
BGC 945; ONX-0801; CB 300945
|
Thymidylate Synthase
|
Cancer
|
|
Idetrexed (ONX 0801) is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
|
-
- HY-13615A
-
|
|
Fluorescent Dye
Folate Receptor (FR)
|
Cancer
|
|
EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .
|
-
- HY-172936
-
|
|
Others
|
Cancer
|
|
L-Serine-S2-PEG-Formic acid is a linker for FGT-4 (HY-172934). FGT-4, a TLR7 agonist, is a folate receptor β (FR-β) targeting chimeric molecule .
|
-
- HY-117602
-
|
|
Toll-like Receptor (TLR)
|
Cancer
|
|
TLR7 agonist 3 (compound 2) is a TLR7 agonist. TLR7 agonist 3 (compound 5) can be coupled to folate receptor binding ligands to target myeloid-derived suppressor cells and exert anticancer activity .
|
-
- HY-P99153
-
|
MORAb-003
|
Antibiotic
|
Cancer
|
|
Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .
|
-
- HY-175428
-
|
|
Antifolate
|
Cancer
|
|
Antifolate agent 1 (Compound 1) is an antifolate agent with one-carbon bridge. Antifolate agent 1 lacks RFC transport and has no affinity for FRα and FRβ and no GARFTase inhibitory activity. Antifolate agent 1 can be used as a negative control for the development of folate receptor-targeting antifolates .
|
-
- HY-D2888C
-
|
Rhodamine B-PEG-FA (MW 2000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 2000) (Rhodamine B-PEG-FA (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 2000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888H
-
|
Rhodamine B-PEG-FA (MW 10000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 10000) (Rhodamine B-PEG-FA (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 10000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888E
-
|
Rhodamine B-PEG-FA (MW 5000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 5000) (Rhodamine B-PEG-FA (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 5000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888A
-
|
Rhodamine B-PEG-FA (MW 600)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 600) (Rhodamine B-PEG-FA (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 600) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888B
-
|
Rhodamine B-PEG-FA (MW 1000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 1000) (Rhodamine B-PEG-FA (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 1000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888
-
|
Rhodamine B-PEG-FA (MW 400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 400) (Rhodamine B-PEG-FA (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 400) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888D
-
|
Rhodamine B-PEG-FA (MW 3400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-FA (MW 3400) (Rhodamine B-PEG-FA (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 3400) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D1716
-
|
|
Fluorescent Dye
Drug Intermediate
|
Cancer
|
|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
|
-
- HY-148194
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC . SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W053583
-
|
DOTA
|
Biochemical Assay Reagents
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .
|
-
- HY-10819
-
|
|
Antifolate
|
Cancer
|
|
AG2034 is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 28 nM against human GARFT, and it binds with high affinity to the folate receptor (Kd of 0.0042 nM). Additionally, AG2034 is a substrate for rat liver folylpolyglutamate synthetase, with a Km of 6.4 µM. AG2034 inhibits the growth of L1210 and CCRF-CEM cells, with IC50 values of 4 nM and 2.9 nM, respectively, and it has demonstrated antitumor activity in xenograft models such as 6C3HED .
|
-
- HY-P10762
-
|
CBP-1008; LDC 10B
|
Peptide-Drug Conjugates (PDCs)
Folate Receptor (FR)
TRP Channel
|
Cancer
|
|
Ricorfotide vedotin (CBP-1008) is a dual-ligand peptide-drug conjugate (PDC) conjugated to MMAE (HY-15162), targeting Folate receptor α (FRα) and TRPV6. Ricorfotide vedotin binds to FRα with high affinity and TRPV6 with low affinity. Ricorfotide vedotin has antitumor activity, and can be used in advanced solid tumor research (eg: colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma and follicular dendritic cell sarcoma) .
|
-
- HY-W053583R
-
|
DOTA (Standard)
|
Biochemical Assay Reagents
Reference Standards
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Tetraxetan (Standard) is the analytical standard of Tetraxetan (HY-W053583). This product is intended for research and analytical applications. Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .
|
-
- HY-172934
-
|
|
Toll-like Receptor (TLR)
NO Synthase
PROTACs
|
Inflammation/Immunology
Cancer
|
|
FGT-4 is a folate receptor β (FR-β) targeting chimeric molecule. FGT-4 is a TLR7 agonist. FGT-4 facilitates the secretion of iNOS and proinflammatory cytokine IL-6 associated with M1 macrophages and enhances the proliferation of cytotoxic CD8 + T cells. FGT-4 has anti-tumor activity in the 4T1 breast cancer mouse model. FGT-4 can be used for the study of cancer immunity. (Pink: target protein TLR7/8 agonist 1 ligand (HY-103698); black: linker (HY-172936); blue: FR-β ligand (HY-172935)) .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1716
-
|
|
Fluorescent Dyes/Probes
|
|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
|
-
- HY-D2523
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-FA (MW 2000) is a fluorescent folate-PEG derivative with excitation/emission wavelengths of ~550 nm/~570 nm. Cy3-PEG-FA (MW 2000) can be readily traced by its intense red fluorescent signal. Cy3-PEG-FA (MW 2000) can be used for cell imaging, folate receptor targeting and detection.
|
-
- HY-D2888C
-
|
Rhodamine B-PEG-FA (MW 2000)
|
Dyes
|
|
RB-PEG-FA (MW 2000) (Rhodamine B-PEG-FA (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 2000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888H
-
|
Rhodamine B-PEG-FA (MW 10000)
|
Dyes
|
|
RB-PEG-FA (MW 10000) (Rhodamine B-PEG-FA (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 10000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888E
-
|
Rhodamine B-PEG-FA (MW 5000)
|
Dyes
|
|
RB-PEG-FA (MW 5000) (Rhodamine B-PEG-FA (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 5000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888A
-
|
Rhodamine B-PEG-FA (MW 600)
|
Dyes
|
|
RB-PEG-FA (MW 600) (Rhodamine B-PEG-FA (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 600) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888B
-
|
Rhodamine B-PEG-FA (MW 1000)
|
Dyes
|
|
RB-PEG-FA (MW 1000) (Rhodamine B-PEG-FA (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 1000) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888
-
|
Rhodamine B-PEG-FA (MW 400)
|
Dyes
|
|
RB-PEG-FA (MW 400) (Rhodamine B-PEG-FA (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 400) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
-
- HY-D2888D
-
|
Rhodamine B-PEG-FA (MW 3400)
|
Dyes
|
|
RB-PEG-FA (MW 3400) (Rhodamine B-PEG-FA (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG-FA (MW 3400) can be used for cell imaging, folate receptor targeting and detection (Ex/Em = 546/610 nm) .
|
| Cat. No. |
Product Name |
Type |
-
- HY-144009
-
|
|
Drug Delivery
|
|
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-167412
-
|
|
Drug Delivery
|
|
PLLA5000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG2000-FOL can be used in drug delivery research .
|
-
- HY-167415
-
|
|
Drug Delivery
|
|
PLLA10000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG5000-FOL can be used in drug delivery research .
|
-
- HY-167413
-
|
|
Drug Delivery
|
|
PLLA20000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG5000-FOL can be used in drug delivery research .
|
-
- HY-167411
-
|
|
Drug Delivery
|
|
PLLA5000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG5000-FOL can be used in drug delivery research .
|
-
- HY-167416
-
|
|
Drug Delivery
|
|
PLLA10000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG2000-FOL can be used in drug delivery research .
|
-
- HY-167414
-
|
|
Drug Delivery
|
|
PLLA20000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG2000-FOL can be used in drug delivery research .
|
-
- HY-W440888B
-
|
|
Drug Delivery
|
|
DSPE-PEG-Folate (MW 3400) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W440888A
-
|
|
Drug Delivery
|
|
DSPE-PEG-Folate (MW 1000) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W440888C
-
|
|
Drug Delivery
|
|
DSPE-PEG-Folate (MW 5000) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W440888
-
|
DSPE-PEG(2000) folate
|
Drug Delivery
|
|
DSPE-PEG-Folate, MW 2000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 2000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 2000 form micelles/lipid bilayer and can be used to targeted drug delivery system research.
|
-
- HY-W440890
-
|
|
Drug Delivery
|
|
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W1123932
-
|
mPEG-folate (MW 1000)
|
Drug Delivery
|
|
mPEG-FA (MW 1000) (mPEG-Folate (MW 1000)) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-W1123932B
-
|
mPEG-folate (MW 5000)
|
Drug Delivery
|
|
mPEG-FA (MW 5000) (mPEG-Folate (MW 5000)) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-W1123932A
-
|
mPEG-folate (MW 2000)
|
Drug Delivery
|
|
mPEG-FA (MW 2000) (mPEG-Folate (MW 2000)) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966D
-
|
BOC-NH-PEG-folate (MW 3400)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 3400) (BOC-NH-PEG-Folate (MW 3400)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966E
-
|
BOC-NH-PEG-folate (MW 5000)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 5000) (BOC-NH-PEG-Folate (MW 5000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966C
-
|
BOC-NH-PEG-folate (MW 2000)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 2000) (BOC-NH-PEG-Folate (MW 2000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966B
-
|
BOC-NH-PEG-folate (MW 1000)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 1000) (BOC-NH-PEG-Folate (MW 1000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966
-
|
BOC-NH-PEG-folate (MW 400)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 400) (BOC-NH-PEG-Folate (MW 400)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966H
-
|
BOC-NH-PEG-folate (MW 10000)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 10000) (BOC-NH-PEG-Folate (MW 10000)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174966A
-
|
BOC-NH-PEG-folate (MW 600)
|
Drug Delivery
|
|
BOC-NH-PEG-FA (MW 600) (BOC-NH-PEG-Folate (MW 600)) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-155882
-
|
mPEG-NH2 (MW 750)
|
Drug Delivery
|
|
mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155880
-
|
mPEG-NH2 (MW 350)
|
Drug Delivery
|
|
mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155883
-
|
mPEG-NH2 (MW 3400)
|
Drug Delivery
|
|
mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155881
-
|
mPEG-NH2 (MW 550)
|
Drug Delivery
|
|
mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155884
-
|
mPEG-NH2 (MW 4000)
|
Drug Delivery
|
|
mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W1123921E
-
|
4-Arm-PEG-folate (MW 5000)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 5000) (4-Arm-PEG-folate (MW 5000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123945
-
|
8-Arm-PEG-folate (MW 400)
|
Drug Delivery
|
|
8-Arm-PEG-FA (MW 400) (8-Arm-PEG-folate (MW 400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123921H
-
|
4-Arm-PEG-folate (MW 10000)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 10000) (4-Arm-PEG-folate (MW 10000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123921
-
|
4-Arm-PEG-folate (MW 400)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 400) (4-Arm-PEG-folate (MW 400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123921A
-
|
4-Arm-PEG-folate (MW 600)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 600) (4-Arm-PEG-folate (MW 600)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123945E
-
|
8-Arm-PEG-folate (MW 5000)
|
Drug Delivery
|
|
8-Arm-PEG-FA (MW 5000) (8-Arm-PEG-folate (MW 5000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123921C
-
|
4-Arm-PEG-folate (MW 2000)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 2000) (4-Arm-PEG-folate (MW 2000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123945H
-
|
8-Arm-PEG-folate (MW 10000)
|
Drug Delivery
|
|
8-Arm-PEG-FA (MW 10000) (8-Arm-PEG-folate (MW 10000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123921B
-
|
4-Arm-PEG-folate (MW 1000)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 1000) (4-Arm-PEG-folate (MW 1000)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W1123921D
-
|
4-Arm-PEG-folate (MW 3400)
|
Drug Delivery
|
|
4-Arm-PEG-FA (MW 3400) (4-Arm-PEG-folate (MW 3400)) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .
|
-
- HY-W888710C
-
|
folate-PEG-COOH (MW 1000)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 1000) (Folate-PEG-COOH (MW 1000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710A
-
|
folate-PEG-COOH (MW 400)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 400) (Folate-PEG-COOH (MW 400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710D
-
|
folate-PEG-COOH (MW 2000)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 2000) (Folate-PEG-COOH (MW 2000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710E
-
|
folate-PEG-COOH (MW 3400)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 3400) (Folate-PEG-COOH (MW 3400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710B
-
|
folate-PEG-COOH (MW 600)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 600) (Folate-PEG-COOH (MW 600)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710H
-
|
folate-PEG-COOH (MW 5000)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 5000) (Folate-PEG-COOH (MW 5000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710I
-
|
folate-PEG-COOH (MW 10000)
|
Drug Delivery
|
|
FA-PEG-COOH (MW 10000) (Folate-PEG-COOH (MW 10000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-174960E
-
|
6-Arm-PEG-folate (MW 5000)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 5000) (6-Arm-PEG-Folate (MW 5000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960B
-
|
6-Arm-PEG-folate (MW 1000)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 1000) (6-Arm-PEG-Folate (MW 1000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960D
-
|
6-Arm-PEG-folate (MW 3400)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 3400) (6-Arm-PEG-Folate (MW 3400)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960A
-
|
6-Arm-PEG-folate (MW 600)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 600) (6-Arm-PEG-Folate (MW 600)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960C
-
|
6-Arm-PEG-folate (MW 2000)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 2000) (6-Arm-PEG-Folate (MW 2000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
-
- HY-174960
-
|
6-Arm-PEG-folate (MW 400)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 400) (6-Arm-PEG-Folate (MW 400)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
- HY-174960H
-
|
6-Arm-PEG-folate (MW 10000)
|
Drug Delivery
|
|
6-Arm-PEG-FA (MW 10000) (6-Arm-PEG-Folate (MW 10000)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
|
- HY-W115607
-
|
Poly(ethylene glycol)-bis-amine (MW 8000)
|
Drug Delivery
|
|
PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
- HY-W591632
-
|
Poly(ethylene glycol)-bis-amine (MW 1000)
|
Drug Delivery
|
|
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
- HY-W053583
-
|
DOTA
|
Biochemical Assay Reagents
|
|
Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .
|
- HY-W053583R
-
|
DOTA (Standard)
|
Biochemical Assay Reagents
|
|
Tetraxetan (Standard) is the analytical standard of Tetraxetan (HY-W053583). This product is intended for research and analytical applications. Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10501A
-
|
|
Antifolate
|
Cancer
|
|
FRα-targeting peptide C7 TFA is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 TFA can be used in the research of tumor diagnosis and treatment .
|
-
- HY-P11024
-
|
|
Folate Receptor (FR)
|
Cancer
|
|
NVP-EVS459 is a Folate Receptor (FR)-targeting radioconjugate. NVP-EVS459 labeled with 177Lu can be used for tumor diagnosis and treatment research .
|
-
- HY-P10501
-
|
|
Antifolate
|
Cancer
|
|
FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment .
|
-
- HY-P10762
-
|
CBP-1008; LDC 10B
|
Peptide-Drug Conjugates (PDCs)
Folate Receptor (FR)
TRP Channel
|
Cancer
|
|
Ricorfotide vedotin (CBP-1008) is a dual-ligand peptide-drug conjugate (PDC) conjugated to MMAE (HY-15162), targeting Folate receptor α (FRα) and TRPV6. Ricorfotide vedotin binds to FRα with high affinity and TRPV6 with low affinity. Ricorfotide vedotin has antitumor activity, and can be used in advanced solid tumor research (eg: colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma and follicular dendritic cell sarcoma) .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99612
-
|
MORAb-202
|
Antibody-Drug Conjugates (ADCs)
|
Cancer
|
|
Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.
|
-
- HY-P99225
-
|
M9346A
|
Antifolate
ADC Antibody
|
Cancer
|
|
Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
|
-
- HY-P99153
-
|
MORAb-003
|
Antibiotic
|
Cancer
|
|
Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .
|
-
- HY-P99225A
-
|
M9346A (powder)
|
Antifolate
ADC Antibody
|
Cancer
|
|
Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-13728
-
|
ZD 9331; BGC9331
|
|
Alkynes
|
|
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-148194
-
|
|
|
DBCO
|
|
SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC . SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-10822A
-
|
BGC 945 trisodium; ONX 0801 trisodium; CB 300945 trisodium
|
|
Alkynes
|
|
Idetrexed (ONX 0801) trisodium is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed trisodium can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
|
-
- HY-10822
-
|
BGC 945; ONX-0801; CB 300945
|
|
Alkynes
|
|
Idetrexed (ONX 0801) is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-144009
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W440888
-
|
DSPE-PEG(2000) folate
|
|
Pegylated Lipids
|
|
DSPE-PEG-Folate, MW 2000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 2000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 2000 form micelles/lipid bilayer and can be used to targeted drug delivery system research.
|
-
- HY-W440890
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-155882
-
|
mPEG-NH2 (MW 750)
|
|
Polymers
|
|
mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155881
-
|
mPEG-NH2 (MW 550)
|
|
Polymers
|
|
mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W115607
-
|
Poly(ethylene glycol)-bis-amine (MW 8000)
|
|
Polymers
|
|
PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155880
-
|
mPEG-NH2 (MW 350)
|
|
Polymers
|
|
mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155883
-
|
mPEG-NH2 (MW 3400)
|
|
Polymers
|
|
mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155884
-
|
mPEG-NH2 (MW 4000)
|
|
Polymers
|
|
mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W591632
-
|
Poly(ethylene glycol)-bis-amine (MW 1000)
|
|
Polymers
|
|
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
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