6-Arm-PEG-FA (MW 600)  (Synonyms: 6-Arm-PEG-Folate (MW 600))

6-Arm-PEG-FA (MW 600) (6-Arm-PEG-Folate (MW 600)) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery^[1].

600 (Average)

O=C(CCC(C(O)=O)NC(C(C=C1)=CC=C1NCC2=NC(C3=O)=C(N=C(N3)N)N=C2)=O)NCCOCCOC[C@H]([C@@H]([C@H]([C@@H](COCCOCCNC(CCC(C(O)=O)NC(C(C=C4)=CC=C4NCC5=NC(C6=O)=C(N=C(N6)N)N=C5)=O)=O)OCCOCCNC(CCC(C(O)=O)NC(C(C=C7)=CC=C7NCC8=NC(C9=O)=C(N=C(N9)N)N=C8)=O)=O)OCCOCCNC(CCC(C(O)=O)NC(C(C=C%10)=CC=C%10NCC%11=NC(C%12=O)=C(N=C(N%12)N)N=C%11)=O)=O)OCCOCCNC(CCC(C(O)=O)NC(C(C=C%13)=CC=C%13NCC%14=NC(C%15=O)=C(N=C(N%15)N)N=C%14)=O)=O)OCCOCCNC(CCC(C(O)=O)NC(C(C=C%16)=CC=C%16NCC%17=NC(C%18=O)=C(N=C(N%18)N)N=C%17)=O)=O.[n].[n].[n].[n].[n].[n]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Zhang L , et al. PEGylated denatured bovine serum albumin modified water-soluble inorganic nanocrystals as multifunctional drug delivery platforms. J Mater Chem B. 2013 Mar 7;1(9):1289-1295.