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Results for "

coumarin compound

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aminoacyl-tRNA Synthetase (1) Apoptosis (4) Bacterial (7) Biochemical Assay Reagents (4) Calcium Channel (5) Cannabinoid Receptor (1) Drug Derivative (2) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (3) Fluorescent Dye (6) Fungal (3) Influenza Virus (1) Interleukin Related (2) Isotope-Labeled Compounds (2) JNK (2) MMP (2) NF-κB (1) NO Synthase (1) Parasite (2) PERK (2) Reference Standards (5) Tyrosinase (1)
By Research Areas:	Cancer (14) Cardiovascular Disease (4) Infection (11) Inflammation/Immunology (14) Metabolic Disease (1) Neurological Disease (9)

By Targets:

Aminoacyl-tRNA Synthetase (1)

Apoptosis (4)

Bacterial (7)

Biochemical Assay Reagents (4)

Calcium Channel (5)

Cannabinoid Receptor (1)

Drug Derivative (2)

Drug Intermediate (1)

Drug Metabolite (1)

Endogenous Metabolite (3)

Fluorescent Dye (6)

Fungal (3)

Influenza Virus (1)

Interleukin Related (2)

Isotope-Labeled Compounds (2)

JNK (2)

MMP (2)

NF-κB (1)

NO Synthase (1)

Parasite (2)

PERK (2)

Reference Standards (5)

Tyrosinase (1)

By Research Areas:

Cancer (14)

Cardiovascular Disease (4)

Infection (11)

Inflammation/Immunology (14)

Metabolic Disease (1)

Neurological Disease (9)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2488

Demethylsuberosin 4 Publications Verification 7-Demethylsuberosin	Calcium Channel NO Synthase	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound found in Angelica gigas Nakai. Demethylsuberosin exerts antihypertensive effects by inhibiting the L-type Ca_V1.2 channel. Demethylsuberosin has antioxidant and anti-inflammatory activities. Demethylsuberosin also exhibits neuroprotective activities against glutamate-induced toxicity in primary cultured rat cortical cells .

HY-W027968

Coumarin-3-carboxylic Acid 2 Publications Verification 2-Oxochromene-3-carboxylic acid	Fluorescent Dye	Cancer
Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line .

HY-D0046

Coumarin-6-sulfonyl chloride 2-Oxo-2H-chromene-6-sulfonyl chloride	Biochemical Assay Reagents	Others
Coumarin-6-sulfonyl chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-109714

3,4-Benzocoumarin	Drug Derivative	Inflammation/Immunology
3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties . 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC₅₀ of 919.2 ng/mL .

HY-N8632

Qianhucoumarin A	Others	Others
Qianhucoumarin A is a natural coumarin compound found in the roots of Peucedanum praeruptorum Dunn .

HY-N9531

3'-Hydroxyxanthyletin	Bacterial	Infection
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-116931

Kelletinin I	Others	Others
Kelletinin I is a coumarin compound with anti-HIV-1 activity.

HY-N10169

Edgeworin	Others	Others
Edgeworin is a coumarin compound can be isolated from the root and stem of Edgeworthia .

HY-N10029

Edgeworoside C	Others	Others
Edgeworoside C (compound 5) is a coumarin isolated from the flower buds of Edgeworthia chrysantha .

HY-W094665

7-(Diethylamino)-4-(hydroxymethyl)coumarin	Biochemical Assay Reagents	Others
7-(Diethylamino)-4-(hydroxymethyl)coumarin (compound 10) is an organic compound that can be used as a photosensitizer in organic synthesis .

HY-N10978

(-)-8-Methoxyobliquin	Others	Others
(-)-8-Methoxyobliquin is a coumarin compound that can be isolated from the aerial parts ofH. heterophyllus .

HY-N2623

Alloimperatorin 1 Publications Verification Prangenidin	Others	Cancer
Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity .

HY-N6658

6-Hydroxy-4-methylcoumarin	Drug Metabolite	Cancer
6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity .

HY-N10015

7-Methoxy-4-methyl-coumarin-8-ol	Others	Others
7-Methoxy-4-methyl-coumarin-8-ol (compound 31) is a compound isolated from sour orange (Citrus aurantium) .

HY-W150273

6-Aminocoumarin hydrochloride	Biochemical Assay Reagents	Others
6-Aminocoumarin hydrochloride is a coumarin dye, which belongs to the donor-acceptor compounds as it contains a donor amine group and an acceptor carbonyl group .

HY-N15523

Moracin M 6-β-D-glucopyranoside	Others	Others
Moracin M 6-β-D-glucopyranoside is found in Morus alba. Moracin M 6-β-D-glucopyranoside is a derivative of coumarin compounds .

HY-N2558

Murrayone	Others	Cancer
Murrayone, a coumarin-containing compound extracted from M. paniculata, is the most bioactive substance in this species and is a cancer metastasis chemopreventive agent based on its unique pharmacological properties .

HY-138145

8-Acetyl-7-hydroxycoumarin	Fungal Bacterial	Infection
8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .

HY-N8618

Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol	Others	Others
Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol was identified as one of the phenolic compounds isolated from Canadian maple syrup (MS-BuOH). It exhibited antioxidant properties along with other phenolic compounds and coumarins isolated from the syrup. These compounds showed varying degrees of antioxidant activity, with phenolic derivatives and coumarins showing superior activity, more so than lignans and flavonoids. This study marks the first time that 16 of the 23 phenolic compounds, including Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol, have been identified in maple syrup .

HY-163397

Antibacterial agent 196	Fungal	Infection
Antibacterial agent 196 (compound 6b) is a coumarin derivative containing oxime ether structure, and shows antifungal activity, with the EC₅₀ of 0.46 μg/mL against Rhizoctonia solani .

HY-N9206

Kimcuongin	Others	Cardiovascular Disease
Kimcuongin (compound 1)is a coumarin that can be found in Murraya paniculata. Kimcuongin shows vasorelaxant activity with an IC₅₀ value of 37.7 μM. Kimcuongin can be used as a vasodilator .

HY-117754

PSB-SB1202	Cannabinoid Receptor	Neurological Disease
PSB-SB1202 (Compound 21a) is a phenyl coumarin compound. PSB-SB1202 is a CB1/CB2 agonist with EC₅₀ values of 56 and 14 nM, and K_i values of 32 and 49 nM, respectively .

HY-N7650

Dihydroseselin	Biochemical Assay Reagents	Others
Dihydroseselin is a derivative of 7-hydroxycoumarin (HY-N0573). 7-hydroxycoumarin, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent

HY-D0066

7-Diethylaminocoumarin-3-carbohydrazide DCCH	Fluorescent Dye	Others
7-Diethylaminocoumarin-3-carbohydrazide is a coumarin. 7-Diethylaminocoumarin-3-carbohydrazide can be used to detect sugar chains and quantify biological carbonyl compounds .

HY-Y1298

Methyl acetylacetate 1 Publications Verification Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases .

HY-128105

1,2-Dihydroxynaphthalene	Bacterial	Others
1,2-Dihydroxynaphthalene is an intermediate isolated from the metabolism of naphthalene and has been shown to be a precursor to the formation of naphthoquinones. 1,2-Dihydroxynaphthalene can be further metabolized by some bacteria (such as Pseudomonas) to compounds such as coumarins and salicylic acid .

HY-N12875

Ailancoumarin E	Tyrosinase	Others
Ailancoumarin E (Compound 5) is a derivative of Coumarin (HY-N0709). Ailancoumarin E exhibits antifeedant activity toward Plutella xylostella, and inhibits growth of third instar larva. Ailancoumarin E inhibits tyrosinase with IC₅₀ of 14.21 μM .

HY-N0081

(±)-Praeruptorin A	Calcium Channel NF-κB Interleukin Related	Cardiovascular Disease Inflammation/Immunology
(±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .

HY-N15662

Coumestan	Drug Intermediate	Infection Neurological Disease Inflammation/Immunology Cancer
Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol (HY-N2335), Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective .

HY-N4109

Decursinol 1 Publications Verification	Calcium Channel PERK JNK MMP	Neurological Disease Inflammation/Immunology Cancer
Decursinol is an orally active coumarin compound that can be isolated from the roots of Angelica gigas. Decursinol is also a metabolite of Decursin (HY-18981) and Decursinol angelate (HY-N4322). Decursinol exhibits multiple activities such as analgesic, antinociceptive, anti-inflammatory, antioxidant, antimetastatic, and neuroprotective effects. Decursinol can be used for research on diseases such as tumors and nervous system disorders .

HY-N6856

4-Hydroxycoumarin	Bacterial Endogenous Metabolite	Infection Cancer
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-149958

Antileishmanial agent-17	Parasite	Infection
Antileishmanial agent-17 is a coumarin hybrid compound with antileishmanial effects (IC₅₀ <0.78 μM). Antileishmanial agent-17 is safe to normal VERO cells. Antileishmanial agent-17 binds to folate pathway enzymes pteridine reductase and DHFR-TS. And Antileishmanial agent-17 shows the most potent with IC₅₀ value of 0.40 μM against promastigote and 0.68 μM against amastigote, respectivley.

HY-163457

Antileishmanial agent-27	Aminoacyl-tRNA Synthetase Parasite	Infection
Antileishmanial agent-27 (compound 7j) is a benzothiazolo-coumarin derivative. Antileishmanial agent-27 is a competitive inhibitor of arginyl-tRNA synthetases (ArgRSs). Antileishmanial agent-27 shows selectivity toward ArgRS of Leishmania donovani (LdArgRS) than its human counterpart (HsArgRS), with IC₅₀ values of 1.2 and 19 μM, respectively. Antileishmanial agent-27 possesses high pharmacokinetic properties .

HY-N0081R

(±)-Praeruptorin A (Standard)	Reference Standards Calcium Channel Interleukin Related	Cardiovascular Disease Inflammation/Immunology
(±)-Praeruptorin A (Standard) is the analytical standard of (±)-Praeruptorin A (HY-N0081). This product is intended for research and analytical applications. (±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .

HY-135646

Eleutheroside B1	Influenza Virus	Infection Inflammation/Immunology
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC₅₀ value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .

HY-76779

4-(Chloromethyl)-7-hydroxycoumarin	Drug Derivative	Cancer
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .

HY-N0573

Umbelliferone 3 Publications Verification 7-Hydroxycoumarin; Hydrangin; NSC 19790	Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-N4109R

Decursinol (Standard)	Reference Standards Calcium Channel PERK JNK MMP	Neurological Disease Inflammation/Immunology Cancer
Decursinol (Standard) is the analytical standard of Decursinol (HY-N4109). This product is intended for research and analytical applications. Decursinol is an orally active coumarin compound that can be isolated from the roots of Angelica gigas. Decursinol is also a metabolite of Decursin (HY-18981) and Decursinol angelate (HY-N4322). Decursinol exhibits multiple activities such as analgesic, antinociceptive, anti-inflammatory, antioxidant, antimetastatic, and neuroprotective effects. Decursinol can be used for research on diseases such as tumors and nervous system disorders .

HY-N3373R

Loganetin (Standard)	Reference Standards Bacterial	Infection
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N6856R

4-Hydroxycoumarin (Standard)	Reference Standards Bacterial Endogenous Metabolite	Infection Cancer
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N0573R

Umbelliferone (Standard) 7-Hydroxycoumarin (Standard); Hydrangin (Standard); NSC 19790 (Standard)	Reference Standards Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone (Standard) (7-Hydroxycoumarin (Standard)) is the analytical standard of Umbelliferone (HY-N0573). This product is intended for research and analytical applications. Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.

HY-N0573S

Umbelliferone-d5 7-Hydroxycoumarin-d₅; Hydrangin-d₅; NSC 19790-d₅	Isotope-Labeled Compounds Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone-d₅ (7-Hydroxycoumarin-d₅) is the deuterium labeled Umbelliferone (HY-N0573 ). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-158402

Anti-inflammatory agent 84	Bacterial Fungal	Infection Inflammation/Immunology
Anti-inflammatory agent 84 (Compound 4D) is a derivative of Coumarin (HY-N0709) with antimicrobial and anti-inflammatory activities. Anti-inflammatory agent 84 inhibits E. coli, Candida albicans, Staphylococcus aureus and methicillin-resistant S. aureus (MRSA), with MIC of 312, 156, 19 and 316 μg/mL, respectively. Anti-inflammatory agent 84 inhibits biofilm formation of S. aureus, E. coli and MRSA, with IC₅₀ of 185, 321 and 99 μM, respectively. Anti-inflammatory agent 84 inhibits nitric oxide production in Lipopolysaccharide (HY-D1056)-stimulated RAW264.7 macrophage cell .

HY-W777393

Umbelliferone-13C6 7-Hydroxycoumarin-¹³C₆; Hydrangin-¹³C₆; NSC 19790-¹³C₆	Isotope-Labeled Compounds Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone- ¹³C₆ (7-Hydroxycoumarin- ¹³C₆) is the ¹³C-labeled Umbelliferone (HY-N0573). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

Cat. No.	Product Name

HY-L0107V

Life Chemicals Natural Product-like Compound Library	13,236 compounds
Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Nowadays, new drugs based on Natural products are successfully applied to treat tumors, viral and bacterial diseases, and nervous disorders. In response to the current drug discovery demand, we created this natural product-like compound library with 13,236 in-stock synthetic compounds similar to natural ones. The library was designed by 2D fingerprint similarity filtering, chemical descriptor-based and natural-likeness scoring selection. These compounds are useful tools for high throughput screening (HTS) and high content screening (HCS) programs.

Life Chemicals Natural Product-like Compound Library

13,236 compounds

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Nowadays, new drugs based on Natural products are successfully applied to treat tumors, viral and bacterial diseases, and nervous disorders. In response to the current drug discovery demand, we created this natural product-like compound library with 13,236 in-stock synthetic compounds similar to natural ones. The library was designed by 2D fingerprint similarity filtering, chemical descriptor-based and natural-likeness scoring selection. These compounds are useful tools for high throughput screening (HTS) and high content screening (HCS) programs.

Cat. No.	Product Name	Type

HY-D0066

7-Diethylaminocoumarin-3-carbohydrazide DCCH	Dyes
7-Diethylaminocoumarin-3-carbohydrazide is a coumarin. 7-Diethylaminocoumarin-3-carbohydrazide can be used to detect sugar chains and quantify biological carbonyl compounds .

Cat. No.	Product Name	Type

HY-D0046

Coumarin-6-sulfonyl chloride 2-Oxo-2H-chromene-6-sulfonyl chloride	Biochemical Assay Reagents
Coumarin-6-sulfonyl chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W150273

6-Aminocoumarin hydrochloride	Microbial Culture
6-Aminocoumarin hydrochloride is a coumarin dye, which belongs to the donor-acceptor compounds as it contains a donor amine group and an acceptor carbonyl group .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2488

Demethylsuberosin 4 Publications Verification 7-Demethylsuberosin	Structural Classification Monophenols Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Umbelliferae Plants Inflammation/Immunology Disease Research Fields Echinacea angustifolia DC.	Calcium Channel NO Synthase
Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound found in Angelica gigas Nakai. Demethylsuberosin exerts antihypertensive effects by inhibiting the L-type Ca_V1.2 channel. Demethylsuberosin has antioxidant and anti-inflammatory activities. Demethylsuberosin also exhibits neuroprotective activities against glutamate-induced toxicity in primary cultured rat cortical cells .

HY-N10978

(-)-8-Methoxyobliquin	Structural Classification Source classification Coumarins Phenylpropanoids Plants Compositae Albizia glaberrima (Schumach. & Thonn.) Benth.	Others
(-)-8-Methoxyobliquin is a coumarin compound that can be isolated from the aerial parts ofH. heterophyllus .

HY-N2623

Alloimperatorin 1 Publications Verification Prangenidin	Monophenols Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Cancer	Others
Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity .

HY-N10015

7-Methoxy-4-methyl-coumarin-8-ol	Citrus × aurantium Linnaeus Monophenols Classification of Application Fields Source classification Other Diseases Rutaceae Coumarins Phenols Phenylpropanoids Plants Disease Research Fields	Others
7-Methoxy-4-methyl-coumarin-8-ol (compound 31) is a compound isolated from sour orange (Citrus aurantium) .

HY-N8632

Qianhucoumarin A	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Qianhucoumarin A is a natural coumarin compound found in the roots of Peucedanum praeruptorum Dunn .

HY-N9531

3'-Hydroxyxanthyletin	Infection other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-116931

Kelletinin I	Structural Classification Animals Source classification Phenols Polyphenols	Others
Kelletinin I is a coumarin compound with anti-HIV-1 activity.

HY-N10169

Edgeworin	Structural Classification Edgeworthia chrysantha Lindl. Thymelaeaceae Source classification Coumarins Phenylpropanoids Plants	Others
Edgeworin is a coumarin compound can be isolated from the root and stem of Edgeworthia .

HY-N10029

Edgeworoside C	Structural Classification Edgeworthia chrysantha Lindl. Thymelaeaceae Source classification Coumarins Phenylpropanoids Plants	Others
Edgeworoside C (compound 5) is a coumarin isolated from the flower buds of Edgeworthia chrysantha .

HY-N15523

Moracin M 6-β-D-glucopyranoside	Structural Classification Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	Others
Moracin M 6-β-D-glucopyranoside is found in Morus alba. Moracin M 6-β-D-glucopyranoside is a derivative of coumarin compounds .

HY-N2558

Murrayone	Classification of Application Fields Source classification Murraya paniculata (L.) Jack. Rutaceae Coumarins Phenylpropanoids Plants Disease Research Fields Cancer	Others
Murrayone, a coumarin-containing compound extracted from M. paniculata, is the most bioactive substance in this species and is a cancer metastasis chemopreventive agent based on its unique pharmacological properties .

HY-138145

8-Acetyl-7-hydroxycoumarin	Structural Classification Source classification Coumarins Tagetes lucida Cav. Phenylpropanoids Plants Compositae	Fungal Bacterial
8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .

HY-N8618

Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol	Structural Classification Monophenols Source classification Sapindaceae Phenols Acer saccharum Marshall Plants	Others
Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol was identified as one of the phenolic compounds isolated from Canadian maple syrup (MS-BuOH). It exhibited antioxidant properties along with other phenolic compounds and coumarins isolated from the syrup. These compounds showed varying degrees of antioxidant activity, with phenolic derivatives and coumarins showing superior activity, more so than lignans and flavonoids. This study marks the first time that 16 of the 23 phenolic compounds, including Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol, have been identified in maple syrup .

HY-N9206

Kimcuongin	Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants Murraya exotica L. Mant.	Others
Kimcuongin (compound 1)is a coumarin that can be found in Murraya paniculata. Kimcuongin shows vasorelaxant activity with an IC₅₀ value of 37.7 μM. Kimcuongin can be used as a vasodilator .

HY-N7650

Dihydroseselin	Structural Classification Classification of Application Fields Sunscreen Source classification Other Diseases Coumarins Phenylpropanoids Cosmetic Research Plants Umbelliferae Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Biochemical Assay Reagents
Dihydroseselin is a derivative of 7-hydroxycoumarin (HY-N0573). 7-hydroxycoumarin, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent

HY-Y1298

Methyl acetylacetate 1 Publications Verification Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases .

HY-128105

1,2-Dihydroxynaphthalene	Structural Classification Microorganisms Source classification Phenols Polyphenols	Bacterial
1,2-Dihydroxynaphthalene is an intermediate isolated from the metabolism of naphthalene and has been shown to be a precursor to the formation of naphthoquinones. 1,2-Dihydroxynaphthalene can be further metabolized by some bacteria (such as Pseudomonas) to compounds such as coumarins and salicylic acid .

HY-N12875

Ailancoumarin E	Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Source classification Coumarins Phenylpropanoids Plants	Tyrosinase
Ailancoumarin E (Compound 5) is a derivative of Coumarin (HY-N0709). Ailancoumarin E exhibits antifeedant activity toward Plutella xylostella, and inhibits growth of third instar larva. Ailancoumarin E inhibits tyrosinase with IC₅₀ of 14.21 μM .

HY-N0081

(±)-Praeruptorin A	Infection Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Coumarins Phenylpropanoids Umbelliferae Plants Disease Research Fields	Calcium Channel NF-κB Interleukin Related
(±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .

HY-N15662

Coumestan	Structural Classification Source classification Coumarins Sphagneticola calendulacea (L.) Pruski Phenylpropanoids Plants Compositae	Drug Intermediate
Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol (HY-N2335), Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective .

HY-N4109

Decursinol 1 Publications Verification	Structural Classification Pseudognaphalium affine (D. Don) Anderberg Classification of Application Fields Source classification Coumarins Phenylpropanoids Umbelliferae Plants Inflammation/Immunology Disease Research Fields Echinacea angustifolia DC. Cancer	Calcium Channel PERK JNK MMP
Decursinol is an orally active coumarin compound that can be isolated from the roots of Angelica gigas. Decursinol is also a metabolite of Decursin (HY-18981) and Decursinol angelate (HY-N4322). Decursinol exhibits multiple activities such as analgesic, antinociceptive, anti-inflammatory, antioxidant, antimetastatic, and neuroprotective effects. Decursinol can be used for research on diseases such as tumors and nervous system disorders .

HY-N6856

4-Hydroxycoumarin	Infection Structural Classification Classification of Application Fields Source classification Coumarins Phenylpropanoids Endogenous metabolite Disease Research Fields	Bacterial Endogenous Metabolite
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N0081R

(±)-Praeruptorin A (Standard)	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Umbelliferae Plants	Reference Standards Calcium Channel Interleukin Related
(±)-Praeruptorin A (Standard) is the analytical standard of (±)-Praeruptorin A (HY-N0081). This product is intended for research and analytical applications. (±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .

HY-135646

Eleutheroside B1	Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Influenza Virus
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC₅₀ value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .

HY-N0573

Umbelliferone 3 Publications Verification 7-Hydroxycoumarin; Hydrangin; NSC 19790	Structural Classification Monophenols Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Endogenous metabolite Disease Research Fields Cancer	Apoptosis Fluorescent Dye
Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-N4109R

Decursinol (Standard)	Structural Classification Pseudognaphalium affine (D. Don) Anderberg Source classification Coumarins Phenylpropanoids Umbelliferae Plants Echinacea angustifolia DC.	Reference Standards Calcium Channel PERK JNK MMP
Decursinol (Standard) is the analytical standard of Decursinol (HY-N4109). This product is intended for research and analytical applications. Decursinol is an orally active coumarin compound that can be isolated from the roots of Angelica gigas. Decursinol is also a metabolite of Decursin (HY-18981) and Decursinol angelate (HY-N4322). Decursinol exhibits multiple activities such as analgesic, antinociceptive, anti-inflammatory, antioxidant, antimetastatic, and neuroprotective effects. Decursinol can be used for research on diseases such as tumors and nervous system disorders .

HY-N3373R

Loganetin (Standard)	Structural Classification Human Gut Microbiota Metabolites Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Plants Endogenous metabolite	Reference Standards Bacterial
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N6856R

4-Hydroxycoumarin (Standard)	Structural Classification Source classification Coumarins Phenylpropanoids Endogenous metabolite	Reference Standards Bacterial Endogenous Metabolite
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N0573R

Umbelliferone (Standard) 7-Hydroxycoumarin (Standard); Hydrangin (Standard); NSC 19790 (Standard)	Structural Classification Monophenols Source classification Coumarins Phenols Phenylpropanoids Endogenous metabolite	Reference Standards Apoptosis Fluorescent Dye
Umbelliferone (Standard) (7-Hydroxycoumarin (Standard)) is the analytical standard of Umbelliferone (HY-N0573). This product is intended for research and analytical applications. Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.

Cat. No.	Product Name	Chemical Structure

HY-N0573S

Umbelliferone-d5

Umbelliferone-d₅ (7-Hydroxycoumarin-d₅) is the deuterium labeled Umbelliferone (HY-N0573 ). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-W777393

Umbelliferone-13C6

Umbelliferone- ¹³C₆ (7-Hydroxycoumarin- ¹³C₆) is the ¹³C-labeled Umbelliferone (HY-N0573). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

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