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Results for "

chromosomal instability

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Glutathione Peroxidase (1) Kinesin (2) Microtubule/Tubulin (1)
By Research Areas:	Cancer (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Targets Recommended: CRM1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W199190

2-CEES	DNA/RNA Synthesis	Cancer
2-CEES is a mustard gas analog forms only DNA monoadducts. 2-CEES induces centrosome amplification in human and mouse cells. 2-CEES induces centrosome amplification and chromosome instability .

HY-162110

AM-9022	Kinesin Microtubule/Tubulin	Cancer
AM-9022 is an orally active, potent, selective KIF18A inhibitor that can be used for research on cancer .

HY-W127709

Chlorophyll b	Biochemical Assay Reagents Glutathione Peroxidase	Others
Chlorophyll b is an orally active tetrapyrrole derivative and pigment. Chlorophyll b can be obtained from photosynthetic organisms such as plants and algae. Chlorophyll b acts as a hydrogen donor and increases Glutathione levels. Chlorophyll b has antioxidant activity and functionally replaces chlorophyll a in photosystem II to participate in photosynthesis. Chlorophyll b reduces Cisplatin (HY-17394)-induced DNA damage, chromosome instability, and oxidative stress. Chlorophyll b is mainly used in the study of plant photosynthesis mechanism .

HY-179210

ATX020	Kinesin	Cancer
ATX020 is a potent, selective and orally active kinesin KIF18A inhibitor. ATX020 inhibits the ATPase activity of KIF18A in humans, rats and dogs, with IC₅₀ values of 0.11 μM, 0.16 μM and 0.24 μM, respectively. ATX020 shows high selectivity for other motor proteins (CENP-E, Eg5, KIF15, etc.), with IC₅₀ values >10 μM and only has a weak inhibitory effect on KIF19 (IC₅₀ = 6.1 μM). ATX020 can inhibit cancer cells proliferation .

Cat. No.	Product Name	Type

HY-W127709

Chlorophyll b	Biochemical Assay Reagents
Chlorophyll b is an orally active tetrapyrrole derivative and pigment. Chlorophyll b can be obtained from photosynthetic organisms such as plants and algae. Chlorophyll b acts as a hydrogen donor and increases Glutathione levels. Chlorophyll b has antioxidant activity and functionally replaces chlorophyll a in photosystem II to participate in photosynthesis. Chlorophyll b reduces Cisplatin (HY-17394)-induced DNA damage, chromosome instability, and oxidative stress. Chlorophyll b is mainly used in the study of plant photosynthesis mechanism .

Chlorophyll b

Biochemical Assay Reagents

Chlorophyll b is an orally active tetrapyrrole derivative and pigment. Chlorophyll b can be obtained from photosynthetic organisms such as plants and algae. Chlorophyll b acts as a hydrogen donor and increases Glutathione levels. Chlorophyll b has antioxidant activity and functionally replaces chlorophyll a in photosystem II to participate in photosynthesis. Chlorophyll b reduces Cisplatin (HY-17394)-induced DNA damage, chromosome instability, and oxidative stress. Chlorophyll b is mainly used in the study of plant photosynthesis mechanism .

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