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Results for "

chlorine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (1) Biochemical Assay Reagents (13) DNA/RNA Synthesis (1) Drug Derivative (6) Drug Intermediate (2) Estrogen Receptor/ERR (1) Fluorescent Dye (12) Glutathione Peroxidase (1) Herbicide (1) Isotope-Labeled Compounds (1) Ligands for E3 Ligase (1) PD-1/PD-L1 (1) Phosphodiesterase (PDE) (1) Proteasome (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Transthyretin (TTR) (1)
By Research Areas:	Cancer (7) Infection (2) Metabolic Disease (2) Neurological Disease (3)

By Targets:

Antibiotic (1)

Bacterial (1)

Biochemical Assay Reagents (13)

DNA/RNA Synthesis (1)

Drug Derivative (6)

Drug Intermediate (2)

Estrogen Receptor/ERR (1)

Fluorescent Dye (12)

Glutathione Peroxidase (1)

Herbicide (1)

Isotope-Labeled Compounds (1)

Ligands for E3 Ligase (1)

PD-1/PD-L1 (1)

Phosphodiesterase (PDE) (1)

Proteasome (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (1)

Transthyretin (TTR) (1)

By Research Areas:

Cancer (7)

Infection (2)

Metabolic Disease (2)

Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137905

Pomalidomide-amido-C5-PEG2-C6-chlorine	Drug Derivative	Cancer
Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivant of Pomalidomide (HY-10984) .

HY-D0947

Azure A chloride	Fluorescent Dye	Others
Azure A (chloride) is a phenothiazine dye. Azure A (chlorine) is formed by oxidation of methylene blue and has strong metachromatic. Azure A (chlorine) can be used for the study of stains and redox media for electrochemical biosensing .

HY-128431

Arochlor 1254	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease
Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation .

HY-133629

1,1,1,3-Tetrachloroacetone	Drug Intermediate	Others
1,1,1,3-Tetrachloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133625

1,1-Dibromo-3-chloroacetone	Biochemical Assay Reagents	Others
1,1-Dibromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133628

1,1,3-Tribromo-3-chloroacetone	Biochemical Assay Reagents	Others
1,1,3-Tribromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133626

1,1-Dibromo-3,3-dichloroacetone	Drug Derivative	Others
1,1-Dibromo-3,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133627

1,3-Dibromo-1,3-dichloroacetone	Drug Derivative	Others
1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133658

Chloroiodoacetic acid	Drug Derivative	Others
Chloroiodoacetic acid exists in the water disinfected with chlorine/hypochlorite .

HY-Y0537K

Potassium chloride, ACS, 99.0%	Biochemical Assay Reagents	Others
Potassium chloride, ACS, 99.0% is a metal halide salt composed of potassium and chlorine .

HY-122146

Bactobolin B Alanylbactobolin; Y-12896	Antibiotic Bacterial	Infection Cancer
Bactobolin B (Alanylbactobolin) is a chlorine-containing antibiotic with antitumor activities .

HY-D2856

FITC-PEG-Br (MW 1000)	Fluorescent Dye	Others
FITC-PEG-Br (MW 1000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2854B

FITC-PEG-CL (MW 2000)	Fluorescent Dye	Others
FITC-PEG-CL (MW 2000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2854D

FITC-PEG-CL (MW 5000)	Fluorescent Dye	Others
FITC-PEG-CL (MW 5000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2856A

FITC-PEG-Br (MW 2000)	Fluorescent Dye	Others
FITC-PEG-Br (MW 2000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2854E

FITC-PEG-CL (MW 10000)	Fluorescent Dye	Others
FITC-PEG-CL (MW 10000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2854A

FITC-PEG-CL (MW 1000)	Fluorescent Dye	Others
FITC-PEG-CL (MW 1000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2854C

FITC-PEG-CL (MW 3400)	Fluorescent Dye	Others
FITC-PEG-CL (MW 3400) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2856B

FITC-PEG-Br (MW 3400)	Fluorescent Dye	Others
FITC-PEG-Br (MW 3400) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2854

FITC-PEG-CL (MW 400)	Fluorescent Dye	Others
FITC-PEG-CL (MW 400) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2856D

FITC-PEG-Br (MW 10000)	Fluorescent Dye	Others
FITC-PEG-Br (MW 10000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-D2856C

FITC-PEG-Br (MW 5000)	Fluorescent Dye	Others
FITC-PEG-Br (MW 5000) is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).

HY-116772

Cyanox CY 1790 Irganox 1790	Biochemical Assay Reagents	Others
Cyanox CY 1790 (Irganox 1790) is an antioxidant with chlorine dioxide resistance .

HY-133602

Tetrachloroguaiacol	Biochemical Assay Reagents	Others
Tetrachloroguaiacol is the major chlorinated phenol produced during chlorine bleaching of wood pulp .

HY-133603

4,5-Dichloroveratrole	Drug Derivative	Others
4,5-Dichloroveratrole is a chlorinated product formed by reaction of Veratryl alcohol (VE; HY-107858) with chlorine dioxide solution .

HY-W460141

Thalidomide 4-chloro	Ligands for E3 Ligase	Cancer
Thalidomide 4-chloro is a chlorinated E3 ligase activator. Thalidomide 4-chloro may be used for further derivitization by substitution of chlorine.

HY-134404

6-Cl-PuTP	Biochemical Assay Reagents	Infection
6-Cl-PuTP is an ATP analog with active chlorine functionality. 6-Cl-PuTP can be used in viral disease related research .

HY-133646

Bromochloroacetonitrile	DNA/RNA Synthesis	Others
Bromochloroacetonitrile is a by-product of the chlorine disinfection of water containing natural organic material. Bromochloroacetonitrile possesses direct acting mutagenic activity and is capable of inducing DNA strand breakage .

HY-W007398

5,6-Dichloronicotinic acid	Biochemical Assay Reagents	Metabolic Disease
5,6-Dichloronicotinic acid is a compound produced by the reaction of 6-Hydroxynicotinic acid (HY-W001996) with chlorine. 5,6-Dichloronicotinic acid can be used as diet pills .

HY-127074

Chlorendic acid HET acid	Biochemical Assay Reagents	Others
Chlorendic acid (HET acid) can be used as a diacid component for the synthesis of oligoesters with potential flame retardant properties with aliphatic diols. Degradation by chlorine radicals may be responsible for the flame retardancy of HET acid-based oligoesters .

HY-134406

6-Cl-cPuMP sodium	Phosphodiesterase (PDE)	Neurological Disease
6-Cl-cPuMP (sodium) is a cAMP analog with active chlorine function. 6-Cl-cPuMP (sodium) has good membrane permeability and phosphodiesterase (PDE) stability. 6-Cl-cPuMP (sodium) can be used for nervous system research .

HY-W777866

(Rac)-1-Linoleoyl-2-stearoyl-3-chloropropanediol	Biochemical Assay Reagents	Others
(Rac)-1-Linoleoyl-2-stearoyl-3-chloropropanediol is a diacylglycerol that contains Linoleic acid at the sn-1 position and stearic acid group at the sn-2 position. The chlorine is a good leaving group and can undergo substitution reactions.

HY-176305S

Neurofilament, U-15N	Isotope-Labeled Compounds	Neurological Disease
Neurofilament, U- ¹⁵N is the ¹⁵N-labeled Neurofilament.

HY-W702728

rac 1-Palmitoyl-2-chloropropanediol	Biochemical Assay Reagents	Others
rac 1-Palmitoyl-2-chloropropanediol is a monoacylglycerol of palmitic acid at the sn-1 position and a chloride group at the sn-2 position. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The chlorine is a good leaving group and can undergo substitution reactions.

HY-Y0678

1,3,5-Trimethoxybenzene TRIMETHYL PHLOROGLUCINOL	Biochemical Assay Reagents	Others
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl ⁺) and free bromine (Br ⁺). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .

HY-119417A

Chloramben sodium	Herbicide	Others
Chloramben sodium is a herbicide with anti-growth activity against plants. Chloramben sodium can be effectively removed by photo-Fenton reaction under natural pH conditions, showing good degradation performance. The removal rate of chloramben sodium is consistent with different electrodes, mainly due to the oxidation mediated by the hydroxyl ions formed in the Fenton reaction. Chloramben sodium is almost completely mineralized using IrO2-based electrodes at high current density, indicating that it can be effectively degraded under light. Chloramben sodium leads to the formation of persistent chlorine derivatives in chlorine-containing environments, so the removal rate and mineralization rate are slightly reduced. Chloramben sodium can form intermediates with a variety of aromatic compounds and organic acids, reflecting the complexity of its transformation in the environment .

HY-W041171

3-Chloro-L-tyrosine 1 Publications Verification 3-Chlorotyrosine	Glutathione Peroxidase	Others
3-Chloro-L-tyrosine is a specific biomarker in myeloperoxidase-catalyzed oxidation. 3-Chloro-L-tyrosine can be used as a molecular marker for oxidative stress and inflammation to determine whether myeloperoxidase-mediated tyrosine chlorination occurs. 3-Chloro-L-tyrosine is therefore used in the diagnosis of chlorine poisoning in forensic toxicology and in the auxiliary diagnosis of inflammation such as colorectal cancer .

HY-143439

LX-039	Estrogen Receptor/ERR	Cancer
LX-039 is a highly potent, selective and orally active estrogen receptor degrader with EC₅₀ value of 2.29 nM. LX-039 has indole C-3 chlorine atom. LX-039 exhibits excellent mouse pharmacokinetics, low clearance, high C_max and oral exposure. LX-039 has anti-tumor activity .

HY-W030778

Nitrilotriacetic acid 1 Publications Verification Triglycollamic acid	Biochemical Assay Reagents	Others
Nitrilotriacetic acid is an orally active chelating agent for metal ions. Nitrilotriacetic acid is an aminotricarboxylic acid that can sequester metal ions as water soluble complexes. Nitrilotriacetic acid reacts with strong oxidizing agents such as hypochlorite, chlorine, ozone, or oxygen in the presence of palladium/carbon catalyst. Nitrilotriacetic acid interacts with solid phases such as cell membranes and bone matrices in the mammalian system. Nitrilotriacetic acid is classified as an epigenetic rodent carcinogen .

HY-Y0141

3-Amino-6-chloropyridazine	Drug Intermediate	Others
3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds .

HY-169434

LTB Lon-TK-BMS-1	PD-1/PD-L1	Cancer
LTB is a prodrug formed by coupling glycolysis inhibitor (Lonidamine (HY-B0486)) with PD1/PDL1 blocker (BMS-1 (HY-19991)) by thioketal linkage. LTB can further encapsulate photosensitizer chlorine e6 (Ce6) (HY-13594) to construct a co-delivery photodynamic nanoplatform (LTB-6 NPs) by self-assembly .

HY-161505

Transthyretin-IN-3	Transthyretin (TTR)	Others
Transthyretin-IN-3 (compound 6) is a designed benzofuran analogue. Transthyretin-IN-3 selectively binds to plasma transthyretin (TTR) to inhibit Amyloid aggregation (IC₅₀=5.0±0.2 μM). Transthyretin-IN-3 can bind to TTR's thyroxine binding site specifically by carrying chlorine substituents at specific locations in its structure. This binding can prevent TTR tetramers from dissociating into unstable monomers .

HY-76779

4-(Chloromethyl)-7-hydroxycoumarin	Drug Derivative	Cancer
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .

HY-163770

Anticancer agent 233	Proteasome	Cancer
Anticancer agent 233 (compound 5g) is a 3,5-bis(arylmethylene)-4-piperidinone derivative with anticancer activity, with GI₅₀ of 0.25 and 0.23 μM for cervical cancer (HeLa) and colon cancer (HCT116) cell lines, respectively. The chlorine atom on the aromatic ring of Anticancer agent 233 interacts well with the catalytic site of 20S proteasome, inhibiting the activity of 20S proteasome to exert its anticancer effect .

HY-W030778R

Nitrilotriacetic acid (Standard) Triglycollamic acid (Standard)	Biochemical Assay Reagents Reference Standards	Others
Nitrilotriacetic acid (Standard) is the analytical standard of Nitrilotriacetic acid. This product is intended for research and analytical applications. Nitrilotriacetic acid is an orally active chelating agent for metal ions. Nitrilotriacetic acid is an aminotricarboxylic acid that can sequester metal ions as water soluble complexes. Nitrilotriacetic acid reacts with strong oxidizing agents such as hypochlorite, chlorine, ozone, or oxygen in the presence of palladium/carbon catalyst. Nitrilotriacetic acid interacts with solid phases such as cell membranes and bone matrices in the mammalian system. Nitrilotriacetic acid is classified as an epigenetic rodent carcinogen .

Cat. No.	Product Name	Type