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Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice .
Isotianil is a plant defense inducer that has no direct antimicrobial effect but instead activates typical plant defense responses. Isotianil can be used as a plant protection agent for controlling rice blast .
Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos can phosphorylate the -OH group on the serine residue in the active (esteratic) site of ChEs and so inhibit both AChE and BChE activity .
Kevetrin hydrochloride is a potent activator of p53, induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells. Kevetrin a preferential cytotoxic activity against blast cells .
Orysastrobin (Standard) is the analytical standard of Orysastrobin. This product is intended for research and analytical applications. Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice .
CDA-IN-4 (compound VS-24) is a chitin deacetylase (CDA) inhibitor. CDA-IN-4 shows a 61.2% protective effect against rice blast at a concentration of 100 μg/mL .
Iprobenfos (Standard) is the analytical standard of Iprobenfos (HY-B1863). This product is intended for research and analytical applications. Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos can phosphorylate the -OH group on the serine residue in the active (esteratic) site of ChEs and so inhibit both AChE and BChE activity .
5-Heptadec-cis-8-enylresorcinol is a 5-alkylresorcinol that can be isolated from etiolated rice seedlings. 5-Heptadec-cis-8-enylresorcinol is an antifungal agent against the rice blast fungus. 5-Heptadec-cis-8-enylresorcinol mediates DNA relaxation .
SDH-IN-29 (Compound A33) is a SDH inhibitor with an IC50 of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC50s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively). SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew .
(S,R)-GSK321 is the (S,R)-enantiomer of GSK321 (HY-18948). GSK321 is a potent, selective mutant IDH1 inhibitor with IC50 values of 2.9, 3.8, 4.6 and 46 nM for R132G, R132C, R132H and WT IDH1, respectively, and >100-fold selectivity over IDH2. GSK321 induces decrease in intracellular 2-HG, abrogation of the myeloid differentiation block and induction of granulocytic differentiation at the level of leukemic blasts and more immature stem-like cells. GSK321can be used for research of acute myeloid leukemia (AML) and other cancers .
Tolprocarb is an oomyces fungicide, which has a strong inhibitory effect on rice blast fungus Magnaporthe grisea by inhibiting polyketide synthase in melanin synthesis pathway .
Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .
Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .
Actinoplanone A is a polycyclic xanthone antibiotic. Actinoplanone A has strong antimicrobial activities against bacteria and the rice blast fungus. Actinoplanone A is cytotoxic to various tumor cells and has an inhibitory effect on DNA synthesis .
KPT-185 is an orally bioavailable and selective inhibitor of CRM1 and displays potent antiproliferative properties at submicromolar concentrations (IC50=100-500 nM), induces apoptosis, cell-cycle arrest, and myeloid differentiation in AML cell lines and patient blasts .
L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis .
Pyriofenone (IKF-309) is an arylphenyl ketone fungicide used primarily to control powdery mildew on crops such as cereals, rice, fruit trees, and vegetables. Pyriofenone has moderate efficacy against rice blast. Pyriofenone acts through preventive, residual, curative, rainfast, cross-stratum, and fumigant activities .
Pivekimab is a human IgG1 monoclonal antibody that targets interleukin-3 (IL-3) and CD123. Pivekimab is used to synthesize pivekimab sunirine, a CD123-directed antibody-active molecule conjugate (ADC). Pivekimab is used in the study of blastic plasmacytoid dendritic cell neoplasm (BPDCN) .
Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
A-Factor is an inducer of streptomycin biosynthesis in an inactive mutant of Streptomyces griseus. In addition, A-Factor can also induce spore formation during conidial development of Magnaporthe oryzae .
C188-9 (TTI-101) is a STAT3 inhibitor, with a Kd of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts .
Isoprothiolane-d4 is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
Isoprothiolane (Standard) is the analytical standard of Isoprothiolane (HY-B1858). This product is intended for research and analytical applications. Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
CD48 Human Pre-designed siRNA Set A contains three designed siRNAs for CD48 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MGTA-117 is a humanized monoclonal antibody targeting CD117. MGTA-117 can be used for synthesis of antibody-drug conjugate (ADC), utilizing an amanitin payload. MGTA-117 has potent anti-tumor activity and increases survival in three acute myeloid leukemia (AML) xenograft hNSG mice models (Kasumi-1, AML PDX 1 and AML PDX 2). MGTA-117 enables hematopoietic stem cell transplantation (HSCT) preprocessing in AML, myelodysplasia with excess blasts (MDS-EB) and gene therapy .
Cd48 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd48 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen. Gemtuzumab affects cell necrosis by specifically targeting CD33 expressed on the surface of leukaemic cell blasts in acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
GSK321 is a potent, selective mutant IDH1 inhibitor with IC50 values of 2.9, 3.8, 4.6 and 46 nM for R132G, R132C, R132H and WT IDH1, respectively, and >100-fold selectivity over IDH2. GSK321 induces decrease in intracellular α-Hydroxyglutaric acid (2-HG) (HY-113038B), abrogation of the myeloid differentiation block and induction of granulocytic differentiation at the level of leukemic blasts and more immature stem-like cells. GSK321can be used for research of acute myeloid leukemia (AML) and other cancers .
Pivekimab is a human IgG1 monoclonal antibody that targets interleukin-3 (IL-3) and CD123. Pivekimab is used to synthesize pivekimab sunirine, a CD123-directed antibody-active molecule conjugate (ADC). Pivekimab is used in the study of blastic plasmacytoid dendritic cell neoplasm (BPDCN) .
Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen. Gemtuzumab affects cell necrosis by specifically targeting CD33 expressed on the surface of leukaemic cell blasts in acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
MGTA-117 is a humanized monoclonal antibody targeting CD117. MGTA-117 can be used for synthesis of antibody-drug conjugate (ADC), utilizing an amanitin payload. MGTA-117 has potent anti-tumor activity and increases survival in three acute myeloid leukemia (AML) xenograft hNSG mice models (Kasumi-1, AML PDX 1 and AML PDX 2). MGTA-117 enables hematopoietic stem cell transplantation (HSCT) preprocessing in AML, myelodysplasia with excess blasts (MDS-EB) and gene therapy .
5-Heptadec-cis-8-enylresorcinol is a 5-alkylresorcinol that can be isolated from etiolated rice seedlings. 5-Heptadec-cis-8-enylresorcinol is an antifungal agent against the rice blast fungus. 5-Heptadec-cis-8-enylresorcinol mediates DNA relaxation .
Actinoplanone A is a polycyclic xanthone antibiotic. Actinoplanone A has strong antimicrobial activities against bacteria and the rice blast fungus. Actinoplanone A is cytotoxic to various tumor cells and has an inhibitory effect on DNA synthesis .
SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, hFc) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag.
SLAMF2/CD48 is a GPI-anchored glycoprotein that regulates immune cells. It interacts with receptors like CD2 and CD244/2B4, activating LCK and LAT in T-cell signaling. SLAMF2 also phosphorylates CD244, leading to immunological synapse formation and targeted release of cytolytic granules by T-lymphocytes and NK-cells. Its direct interactions with CD2, CD244, and LCK contribute to immune response regulation. SLAMF2/CD48 Protein, Rat (HEK293, His) is the recombinant rat-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-His labeled tag.
CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E (IgE) and complement receptor 2 (CR2/CD21). CD23 regulates IgE production and B-cell differentiation, aiding in IGE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-hFc labeled tag.
CD23/Fc epsilon RII Protein, a low-affinity receptor for IgE and CR2/CD21, regulates IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway. CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding. CD23/Fc epsilon RII Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-His labeled tag.
CD23 or Fc epsilon receptor II (Fc epsilon RII) is a low-affinity receptor for immunoglobulin E (IgE) and complements receptor 2 (CR2/CD21). CD23 is present on B cells, regulates IgE production and B cell differentiation, and aids in IgE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Human (HEK293, His) is the recombinant human-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-8*His labeled tag.
SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-6*His labeled tag.
SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, mFc) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-mFc labeled tag.
SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, His) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-His labeled tag.
SLAMF2/CD48 is a GPI-anchored glycoprotein that regulates immune cells. It interacts with receptors like CD2 and CD244/2B4, activating LCK and LAT in T-cell signaling. SLAMF2 also phosphorylates CD244, leading to immunological synapse formation and targeted release of cytolytic granules by T-lymphocytes and NK-cells. Its direct interactions with CD2, CD244, and LCK contribute to immune response regulation. SLAMF2/CD48 Protein, Rat (HEK293, hFc) is the recombinant rat-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag.
CD48 (SLAMF2) is a member of the CD2 subfamily of immunoglobulin-like receptors, it is held at the cell surface by a Glycosylphosphatidylinositol GPI anchor via a C-terminal domain, and interacts with cell surface receptors including 2B4/CD244 or CD2 via its N-terminal immunoglobulin domain to activate the LCK pathway and regulate immune cell function and activation. SLAMF2/CD48 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag.
CD23 or Fc epsilon receptor II (Fc epsilon RII) is a low-affinity receptor for immunoglobulin E (IgE) and complements receptor 2 (CR2/CD21). CD23 is present on B cells, regulates IgE production and B cell differentiation, and aids in IgE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived CD23/Fc epsilon RII protein, expressed by HEK293, with N-Avi and N-His labeled tag.
Isoprothiolane-d4 is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
CD48 Antibody (YA1111) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1111), targeting CD48. CD48 Antibody (YA1111) can be used for IHC-P experiment in human background.
CD48 Antibody (YA4688) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD48. It can be applicated for ELISA, FC assays, in the background of human.
CD23 Antibody (YA1296) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1296), targeting CD23. CD23 Antibody (YA1296) can be used for IHC-P, ICC/IF, FC experiment in human background.
blast 2 antibody; blast-2 antibody; blast2 antibody; C type lectin domain family 4 member J antibody; C-type lectin domain family 4 antibody; C-type lectin domain family 4 member J antibody; C-type lectin domain family 4; member J antibody; CD 23 antibody; CD 23A antibody; CD23 antibody; CD23 antigen antibody; CD23A antibody; CLEC 4J antibody; CLEC4J antibody; Fc epsilon receptor II antibody; Fc epsilon RII antibody; Fc fragment of IgE antibody; Fc fragment of IgE low affinity II receptor for antibody; Fc fragment of IgE receptor II antibody; Fc fragment of IgE; low affinity II; receptor for; CD23; antibody; Fc of IgE antibody; Fc of IgE; low affinity II; receptor for; CD23; antibody; Fc receptor IgE low affinity II alpha polypeptide antibody; Fc receptor; IgE; low affinity II; alpha polypeptide; isoform CRA_a antibody; Fc-epsilon-RII antibody; FCE 2 antibody; FCE2 antibody; FCER 2 antibody; Fcer2 antibody; FCER2_HUMAN antibody; FCER2A antibody; FceRII antibody; IgE binding factor antibody; IgE receptor lymphocyte antibody; IgE-binding factor antibody; IGEBF antibody; Immunoglobulin E binding factor antibody; Immunoglobulin E receptor antibody; Immunoglobulin E receptor; low affinity II antibody; Immunoglobulin E-binding factor antibody; Immunoglobulin epsilon chain antibody; LEUKOCYTE ANTIGEN CD23 antibody; Low Affinity IgE Receptor antibody; Low affinity immunoglobulin epsilon Fc receptor antibody; Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody; Low affinity immunoglobulin epsilon Fc receptor soluble form antibody; Ly-42 antibody; Ly42 antibody; Lymphocyte antigen CD23 antibody; Lymphocyte IgE receptor antibody; MGC93219 antibody; CD23 nanobody
ELISA, FC
Human
CD23 Antibody (YA4669) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD23. It can be applicated for ELISA, FC assays, in the background of human.
CD48 Human Pre-designed siRNA Set A contains three designed siRNAs for CD48 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cd48 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd48 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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