Search Result
Results for "
azide-containing molecules
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-114354
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BOD FL alkyne
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Fluorescent Dye
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Others
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BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex=503 nm; Em=512 nm), a bright and photostable fluorophore which emits in fluorescein (FAM) channel. BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.
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- HY-W728531
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Biochemical Assay Reagents
p38 MAPK
Potassium Channel
Mitochondrial Metabolism
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Cancer
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Ac4ManNAz can be taken up by cells and is an azide-containing metabolic glycoprotein labeling reagent that selectively modifies proteins. Commonly used for cell labeling, tracking and proteomic analysis. Ac4ManNAz contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Ac4ManNAz can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-34643
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Hept-6-ynoic acid
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Biochemical Assay Reagents
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Others
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6-Heptynoic acid (Hept-6-ynoic acid) is a reagent with an alkyne group and a carboxylic acid. The terminal carboxylic acid can form amide bond with primary amines (activation is needed). The alkyne can form triazole linkage with azide containing molecules via copper catalyzed reactions.
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- HY-123629
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Fluorescent Dye
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Others
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TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-160893
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PSMA
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Cancer
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PSMA-azide is a prostate-specific membrane antigen (PSMA) ligand. PSMA-azide inhibits PSMA-dependent NAAG (N-acetylaspartylglutamic acid) hydrolysis, with an IC50 of 9 nM and a Ki of 1 nM. PSMA-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups .
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- HY-W800687
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Biochemical Assay Reagents
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Others
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Tetra(3-methoxy-n-(prop-2-ynyl)propanamide) methane is a 4-branched molecule with propargyl groups that can be linked to azide-containing biomolecules via Click Chemistry.
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- HY-D2230
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Fluorescent Dye
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Others
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Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
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- HY-W440832
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DSPE-PEG(2000) azide
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Liposome
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Infection
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DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-173606
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Liposome
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Others
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DSPE-PEG2000-Azide ammonium is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG2000-Azide ammonium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2138
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Fluorescent Dye
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Others
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Cy3-PEG7-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 7 PEG units. Cy3-PEG7-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2136
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Fluorescent Dye
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Others
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Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2137
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Fluorescent Dye
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Others
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Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-141091
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Fluorescent Dye
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Others
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Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-161131
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E3 Ligase Ligand-Linker Conjugates
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Inflammation/Immunology
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Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups .
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- HY-173385
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Biochemical Assay Reagents
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Metabolic Disease
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Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .
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- HY-157510
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Thalidomide-O-C3-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C3-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C3-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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- HY-157511
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Thalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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- HY-157515
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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Cat. No. |
Product Name |
Type |
-
- HY-114354
-
BOD FL alkyne
|
Fluorescent Dyes/Probes
|
BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex=503 nm; Em=512 nm), a bright and photostable fluorophore which emits in fluorescein (FAM) channel. BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.
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- HY-D2230
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Fluorescent Dyes/Probes
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Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
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- HY-D2138
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Fluorescent Dyes/Probes
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Cy3-PEG7-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 7 PEG units. Cy3-PEG7-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2136
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Fluorescent Dyes/Probes
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Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2137
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Fluorescent Dyes/Probes
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Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No. |
Product Name |
Type |
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- HY-W440832
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DSPE-PEG(2000) azide
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Drug Delivery
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DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-173606
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Drug Delivery
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DSPE-PEG2000-Azide ammonium is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG2000-Azide ammonium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-173385
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Drug Delivery
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Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .
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Cat. No. |
Product Name |
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Classification |
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- HY-123629
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Azide
PROTAC Synthesis
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TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-160893
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Azide
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PSMA-azide is a prostate-specific membrane antigen (PSMA) ligand. PSMA-azide inhibits PSMA-dependent NAAG (N-acetylaspartylglutamic acid) hydrolysis, with an IC50 of 9 nM and a Ki of 1 nM. PSMA-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups .
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- HY-D2230
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Alkynes
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Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
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- HY-W440832
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DSPE-PEG(2000) azide
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Azide
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DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2138
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Labeling and Fluorescence Imaging
Azide
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Cy3-PEG7-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 7 PEG units. Cy3-PEG7-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2136
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Azide
Labeling and Fluorescence Imaging
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Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2137
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Azide
Labeling and Fluorescence Imaging
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Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-141091
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ADC Synthesis
Azide
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Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-161131
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Azide
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Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups .
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- HY-173385
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Azide
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Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .
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- HY-157510
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Azide
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Thalidomide-O-C3-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C3-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C3-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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- HY-157511
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Azide
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Thalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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- HY-157515
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Azide
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Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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Cat. No. |
Product Name |
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Classification |
-
- HY-W440832
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DSPE-PEG(2000) azide
|
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Pegylated Lipids
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DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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