Search Result
Results for "
asymmetric
" in MedChemExpress (MCE) Product Catalog:
16
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-113216BS
-
|
NG,NG-Dimethylarginine-d6 dihydrochloride
|
Endogenous Metabolite
NO Synthase
|
Others
|
|
Asymmetric-dimethylarginine-d6 (dihydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride .
|
-
-
- HY-113216
-
-
-
- HY-W021068
-
-
-
- HY-142988
-
|
1S-2M-PC
|
Liposome
|
Others
|
|
1-Stearoyl-2-myristoyl-sn-glycero-3-PC (1S-2M-PC) belongs to the class of asymmetric phospholipids. 1-Stearoyl-2-myristoyl-sn-glycero-3-PC is abundant in biological membranes .
|
-
-
- HY-113216AS
-
|
NG,NG-Dimethylarginine-d7 hydrochloride
|
Endogenous Metabolite
|
Others
|
|
Asymmetric dimethylarginine-d7 (hydrochloride) is the deuterium labeled Asymmetric dimethylarginine hydrochloride .
|
-
-
- HY-113216S
-
-
-
- HY-113216B
-
|
NG,NG-Dimethylarginine dihydrochloride
|
NO Synthase
|
Cardiovascular Disease
Cancer
|
|
Asymmetric dimethylarginine dihydrochloride is an endogenous NO synthase inhibitor that reduces NO production, which contributes to endothelial dysfunction and cardiovascular disease .
|
-
-
- HY-113216R
-
-
-
- HY-W112346
-
|
|
Drug Intermediate
|
Others
|
|
4-Amino-2-hydroxybenzohydrazide, an asymmetric unit, comprises two crystallographically independent molecules (A and B) .
|
-
-
- HY-P4487
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H-Pro-Pro-Asp-NH2 is a potent and selective catalyst for asymmetric aldol reactions. H-Pro-Pro-Asp-NH2 catalyzes aldol reactions between acetone and several aldehydes .
|
-
-
- HY-133122
-
|
|
TNF Receptor
|
Inflammation/Immunology
Cancer
|
|
UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar Kd of 13 nM .
|
-
-
- HY-69348
-
|
|
Biochemical Assay Reagents
Drug Intermediate
|
Others
|
|
(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis .
|
-
-
- HY-P99430
-
|
EM901; CC-93269
|
CD3
|
Inflammation/Immunology
Cancer
|
|
Alnuctamab (EM901) is a bispecific T-cell engager targeting BCMA and CD3, belonging to an asymmetric two-armed humanized IgG1 antibody. Alnuctamab can simultaneously bind to BCMA expressed on the surface of myeloma cells and CD3 molecules on the surface of T cells, recruiting T cells to kill tumors. Alnuctamab is used for the research of multiple myeloma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
|
-
-
- HY-168497
-
|
|
Histone Methyltransferase
|
Cancer
|
|
C-MS023 is a photo-activatable MS023 (HY-19615) prodrug, achieving spatiotemporal inhibition of Histone Arginine Asymmetric Dimethylation. C-MS023 inhibits PRMT6 mediated asymmetric dimethylation of H3 arginine 2 (H3R2me2a), with an estimate IC50 of 0.2224 μM. The photolysis of C-MS023 could be triggered by visible light irradiation at 420 nm, thereby liberating MS023 for effective downregulation of histone arginine asymmetric dimethylation and DNA replication-related transcriptomic activities .
|
-
-
- HY-D0839
-
|
TTAB; TTABr; MiTMAB
|
Biochemical Assay Reagents
|
Others
|
|
Tetradecyltrimethylammonium bromide (TTAB; TTABr; MiTMAB), an organic building block, is a cationic surfactant with asymmetrical structure .
|
-
-
- HY-W008033
-
-
-
- HY-W440957
-
|
PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
|
Liposome
|
Cancer
|
|
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
|
-
-
- HY-E70418
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Epoxide hydrolase is an enzyme responsible for catalyzing the reaction between epoxides and water, converting epoxide groups into diols. Epoxide hydrolase plays a key role in the metabolism of environmental pollutants and lipids, contributing to detoxification, inflammation responses, and the regulation of cardiovascular system health. Additionally, epoxide hydrolase can be used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, to produce chiral drug molecules .
|
-
-
- HY-59125
-
|
|
Endogenous Metabolite
|
Others
|
|
(R,R)-(+)-Hydrobenzoin is a chiral vicinal diol and an organic catalyst. (R,R)-(+)-Hydrobenzoin is used in asymmetric catalytic reactions .
|
-
-
- HY-W018845
-
|
Pentamethylcyclopentadienyliridium(III) chloride,dimer
|
Biochemical Assay Reagents
|
Others
|
|
[Ir(Cp-)Cl2]2 is used as a precursor for the asymmetric transfer hydrogenation catalyst of ketones. It is a catalyst for greener amine synthesis .
|
-
![[Ir(Cp-)Cl2]2](//file.medchemexpress.eu/product_pic/hy-w018845.gif)
-
- HY-D0839S1
-
|
TTAB-d29; TTABr-d29; MiTMAB-d29
|
Isotope-Labeled Compounds
|
Others
|
|
Tetradecyltrimethylammonium-d29 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide) . Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure .
|
-
-
- HY-D0839S2
-
|
TTAB-d38 ; TTABr-d38 ; MiTMAB-d38
|
Isotope-Labeled Compounds
|
Others
|
|
Tetradecyltrimethylammonium-d38 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide) . Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure .
|
-
-
- HY-156454
-
-
-
- HY-W002878
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .
|
-
-
- HY-40229
-
|
S-(-)-T-Butylsulfinimide
|
Biochemical Assay Reagents
|
Others
|
|
(S)-(-)-tert-Butylsulfinamide (S-(-)-T-Butylsulfinimide) is a compound containing a chiral sulfur atom. As a chiral auxiliary, (S)-(-)-tert-Butylsulfinamide can be used in the asymmetric synthesis of organic compounds .
|
-
-
- HY-W002502
-
|
Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine
|
Biochemical Assay Reagents
|
Others
|
|
(DHQ)2PHAL (Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine) can be used as a chiral ligand in asymmetric dihydroxylation reactions .
|
-
-
- HY-W019833
-
|
PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
|
Endogenous Metabolite
|
Metabolic Disease
|
|
MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
|
-
-
- HY-157672
-
|
|
Bacterial
|
Others
|
|
18:1-14:0 PC, an asymmetric phospholipid featuring an unsaturated acyl chain in the sn-1 position, can create a hydrophobic surface in mucus by functioning as a surfactant to impede bacterial penetrance, while also serving as a dietary source of choline.
|
-
-
- HY-171951
-
|
|
Liposome
|
Others
|
|
31hP is an asymmetric A 3 lipid. 31hP can facilitate in vivo luciferase expression. 31hP can be rapidly degraded in the presence of esterase owing to two biocleavable ester bonds. 31hP can be used in the synthesis of lipid nanoparticles (LNPs) .
|
-
-
- HY-59125R
-
|
|
Endogenous Metabolite
|
Others
|
|
(R,R)-(+)-Hydrobenzoin (Standard) is the analytical standard of (R,R)-(+)-Hydrobenzoin. This product is intended for research and analytical applications. (R,R)-(+)-Hydrobenzoin is a chiral vicinal diol and an organic catalyst. (R,R)-(+)-Hydrobenzoin is used in asymmetric catalytic reactions .
|
-
-
- HY-W440982
-
|
PC(18:0/18:1); 2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine
|
Liposome
|
Others
|
|
SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can be used for various biochemical studies .
|
-
-
- HY-W002801
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Benzyloxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Benzyloxyphenylboronic acid is also a substrate used in asymmetric Suzuki coupling reactions. 2-Benzyloxyphenylboronic acid can be utilized in the synthesis of other active compounds .
|
-
-
- HY-B2210
-
|
DIPA; Diisopropylamine dichloroacetate
|
Biochemical Assay Reagents
|
Others
|
|
Diisopropylammonium dichloroacetate is an organic compound commonly used as a catalyst and ligand for organic reactions. It can promote various organic chemical reactions, such as olefin addition, carbonylation reaction and asymmetric catalytic reaction, etc. In addition, the compound is also widely used in the research of some medical fields, for example, in the application of anti-tumor therapy.
|
-
-
- HY-W800734
-
|
MPPC; PC(14:0/16:0)
|
Liposome
|
Cancer
|
|
1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
|
-
-
- HY-W009283
-
|
|
Endogenous Metabolite
Biochemical Assay Reagents
|
|
|
2-(2-(Diphenylphosphino)ethyl)pyridine is an important chiral catalyst with excellent catalytic activity. 2-(2-(Diphenylphosphino)ethyl)pyridine is widely used in asymmetric synthesis reactions, especially in the field of compound synthesis. 2-(2-(Diphenylphosphino)ethyl)pyridine can also be used in metal-catalyzed reactions to improve the selectivity and yield of the reaction.
|
-
-
- HY-120967A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(2S)-OMPT triethylamine, a chiral oxirane derivative, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
|
-
-
- HY-120967
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98%, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
|
-
-
- HY-W021016
-
|
(S,S)-Ph-BPE
|
Endogenous Metabolite
Biochemical Assay Reagents
|
Others
|
|
(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane ((S,S)-Ph-BPE) serves as a chiral phosphine ligand in the asymmetric hydrogenation of allylic sulfoxides, through a dynamic kinetic resolution process facilitated by Rh-catalyzed hydrogenation, utilizing insights from both theoretical and experimental mechanistic studies.
|
-
-
- HY-W008270
-
|
γ-Crotonolactone
|
Endogenous Metabolite
|
Others
|
|
2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite. 2(5H)-Furanone is present in a wide variety of biologically active natural products. 2(5H)-Furanone can undergo oraganocatalytic asymmetric direct vinylogous aldo reactions to provide diastereomerically and enantiomerically enriched 5-substituted 2(5H) furanones .
|
-
-
- HY-160412
-
|
SAR-441566; TNFα activity modulator 3
|
TNF Receptor
|
Inflammation/Immunology
|
|
Balinatunfib (SAR-441566) is an orally active inhibitor of TNFR1 signaling. By binding to the central pocket of the soluble TNFα (sTNFα) trimer, Balinatunfib stabilizes an asymmetric conformation, blocking its binding to TNFR1 (without affecting TNFR2) and thus inhibiting downstream pathways. Balinatunfib has anti-inflammatory activity, and can be used in the study of autoimmune diseases .
|
-
-
- HY-N0173
-
|
α-Quinidine
|
Serotonin Transporter
Parasite
|
Infection
|
|
Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .
|
-
-
- HY-111664
-
|
(+)-Citronellal
|
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-(+)-Citronellal can be isolated from citrus, lavender and eucalyptus oils. (R)-(+)-Citronellal is a monoterpenoid aldehyde. (R)-(+)-Citronellal is the main component of citronellal oil with a distinct lemon scent. (R)-(+)-Citronellal is a flavoring agent. Used for insect repellent and antifungal properties. (R)-(+)-Citronellal is a chiral organic compound that can be used as a building block in organic synthesis or a chiral catalyst in asymmetric reactions .
|
-
-
- HY-40228
-
|
(R)-2-Methylpropane-2-sulfinamide
|
Biochemical Assay Reagents
|
Others
|
|
(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .
|
-
-
- HY-75920
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Inhoffen Lythgoe diol is an organic molecule commonly used in chiral selective reactions in organic synthesis. It can be used as a catalyst and a ligand, and has a wide range of applications in the preparation of nitrogen- and sulfur-containing natural products, pharmaceuticals, and material science. Inhoffen Lythgoe diol plays a very important role in the field of asymmetric synthesis. Although it has no direct medical application, it plays an important role in the production and research of many important chemicals.
|
-
-
- HY-24312
-
|
|
Biochemical Assay Reagents
|
Others
|
|
AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.
|
-
-
- HY-124317
-
|
|
Fluorescent Dye
|
Others
|
|
PF-06649283 is a drug with potential intracellular activity. The effects of PF-06649283 may be affected by factors such as cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric intracellular localization. The potency of PF-06649283 at the cellular level may show different activity compared to the recombinant enzyme, and this difference needs to be considered in the drug discovery process. Increased intracellular potency of PF-06649283 may be critical for the development of this drug as a probe or drug .
|
-
-
- HY-N0173R
-
|
α-Quinidine (Standard)
|
Reference Standards
Serotonin Transporter
Parasite
|
Infection
|
|
Cinchonidine (Standard) is the analytical standard of Cinchonidine. This product is intended for research and analytical applications. Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .
|
-
-
- HY-158458
-
|
A2[3]G1F1(a1-3) glycan
|
Biochemical Assay Reagents
|
Others
|
|
A2[3]G1F1(α-1-3) glycan (A2[3]G1F1(a1-3) glycan) is an asymmetric Lewis X polysaccharide and N-glycan. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
|
-
![A2[3]G1F1(α-1-3) glycan](//file.medchemexpress.eu/product_pic/hy-158458.gif)
-
- HY-D0150A
-
|
|
Fluorescent Dye
|
Others
|
|
(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
|
-
-
- HY-111664R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-(+)-Citronellal (Standard) is the analytical standard of (R)-(+)-Citronellal. This product is intended for research and analytical applications. (R)-(+)-Citronellal can be isolated from citrus, lavender and eucalyptus oils. (R)-(+)-Citronellal is a monoterpenoid aldehyde. (R)-(+)-Citronellal is the main component of citronellal oil with a distinct lemon scent. (R)-(+)-Citronellal is a flavoring agent. Used for insect repellent and antifungal properties. (R)-(+)-Citronellal is a chiral organic compound that can be used as a building block in organic synthesis or a chiral catalyst in asymmetric reactions .
|
-
- HY-E70704
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR G719C Recombinant Human Active Protein Kinase is a recombinant EGFR G719C protein that can be used to study EGFR G719C-related functions .
|
-
- HY-E70706
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR L718Q Recombinant Human Active Protein Kinase is a recombinant EGFR L718Q protein that can be used to study EGFR L718Q-related functions .
|
-
- HY-W010507
-
|
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Others
|
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-E70695
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR C797S Recombinant Human Active Protein Kinase is a recombinant EGFR C797S protein that can be used to study EGFR C797S-related functions .
|
-
- HY-E70707
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR L858R Recombinant Human Active Protein Kinase is a recombinant EGFR L858R protein that can be used to study EGFR L858R-related functions .
|
-
- HY-W008270R
-
|
γ-Crotonolactone (Standard)
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
2(5H)-Furanone (Standard) is the analytical standard of 2(5H)-Furanone. This product is intended for research and analytical applications. 2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite. 2(5H)-Furanone is present in a wide variety of biologically active natural products. 2(5H)-Furanone can undergo oraganocatalytic asymmetric direct vinylogous aldo reactions to provide diastereomerically and enantiomerically enriched 5-substituted 2(5H) furanones .
|
-
- HY-E70708
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR L861Q Recombinant Human Active Protein Kinase is a recombinant EGFR L861Q protein that can be used to study EGFR L861Q-related functions .
|
-
- HY-E70705
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR G719S Recombinant Human Active Protein Kinase is a recombinant EGFR G719S protein that can be used to study EGFR G719S-related functions .
|
-
- HY-E70709
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M Recombinant Human Active Protein Kinase is a recombinant EEGFR T790M protein that can be used to study EGFR T790M-related functions .
|
-
- HY-E70703
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d752-759 Recombinant Human Active Protein Kinase is a recombinant EGFR d752-759 protein that can be used to study EGFR d752-759-related functions .
|
-
- HY-E70697
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d746-750 Recombinant Human Active Protein Kinase is a recombinant EGFR d746-750 protein that can be used to study EGFR d746-750-related functions .
|
-
- HY-Y0549
-
|
Diphenylmethane-α-carboxylic Acid
|
Biochemical Assay Reagents
|
Others
|
|
Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .
|
-
- HY-W002530
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
(1S,2R)-1-Aminoindan-2-ol is a chiral resolving agent. (1S,2R)-1-Aminoindan-2-ol efficiently resolves various racemic 2-arylalkanoic acids and precisely controls the stereostructure of the products in asymmetric syntheses. (1S,2R)-1-Aminoindan-2-ol can be used in the synthesis of HIV protease inhibitors .
|
-
- HY-E70711
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR T790M/L858R protein that can be used to study EGFR T790M/L858R-related functions .
|
-
- HY-E70701
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d747-749/A750P Recombinant Human Active Protein Kinase is a recombinant EGFR d747-749/A750P protein that can be used to study EGFR d747-749/A750P-related functions .
|
-
- HY-E70696
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR C797S/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR C797S/L858R protein that can be used to study EGFR C797S/L858R-related functions .
|
-
- HY-E70698
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d746-750/C797S Recombinant Human Active Protein Kinase is a recombinant EGFR d746-750/C797S protein that can be used to study EGFR d746-750/C797S-related functions .
|
-
- HY-E70702
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d747-752/P753S Recombinant Human Active Protein Kinase is a recombinant EGFR d747-752/P753S protein that can be used to study EGFR d747-752/P753S-related functions .
|
-
- HY-D0150
-
|
|
Fluorescent Dye
|
Others
|
|
Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
|
-
- HY-E70699
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d746-750/T790M/C797S Recombinant Human Active Protein Kinase is a recombinant EGFR d746-750/T790M/C797S protein that can be used to study EGFR d746-750/T790M/C797S-related functions .
|
-
- HY-E70710
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M/C797S/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR T790M/C797S/L858R protein that can be used to study EGFR T790M/C797S/L858R-related functions .
|
-
- HY-E70700
-
|
|
EGFR
|
Cancer
|
|
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d746-750/T790M/C797S/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR d746-750/T790M/C797S/L858R protein that can be used to study EGFR d746-750/T790M/C797S/L858R-related functions .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0150
-
|
|
Fluorescent Dyes/Probes
|
|
Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
|
-
- HY-D0150A
-
|
|
Fluorescent Dyes/Probes
|
|
(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
|
| Cat. No. |
Product Name |
Type |
-
- HY-142988
-
|
1S-2M-PC
|
Drug Delivery
|
|
1-Stearoyl-2-myristoyl-sn-glycero-3-PC (1S-2M-PC) belongs to the class of asymmetric phospholipids. 1-Stearoyl-2-myristoyl-sn-glycero-3-PC is abundant in biological membranes .
|
-
- HY-69348
-
|
|
Biochemical Assay Reagents
|
|
(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis .
|
-
- HY-W018845
-
|
Pentamethylcyclopentadienyliridium(III) chloride,dimer
|
Biochemical Assay Reagents
|
|
[Ir(Cp-)Cl2]2 is used as a precursor for the asymmetric transfer hydrogenation catalyst of ketones. It is a catalyst for greener amine synthesis .
|
-
- HY-W002878
-
|
|
Biochemical Assay Reagents
|
|
TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .
|
-
- HY-40229
-
|
S-(-)-T-Butylsulfinimide
|
Biochemical Assay Reagents
|
|
(S)-(-)-tert-Butylsulfinamide (S-(-)-T-Butylsulfinimide) is a compound containing a chiral sulfur atom. As a chiral auxiliary, (S)-(-)-tert-Butylsulfinamide can be used in the asymmetric synthesis of organic compounds .
|
-
- HY-W002502
-
|
Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine
|
Biochemical Assay Reagents
|
|
(DHQ)2PHAL (Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine) can be used as a chiral ligand in asymmetric dihydroxylation reactions .
|
-
- HY-W002801
-
|
|
Biochemical Assay Reagents
|
|
2-Benzyloxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Benzyloxyphenylboronic acid is also a substrate used in asymmetric Suzuki coupling reactions. 2-Benzyloxyphenylboronic acid can be utilized in the synthesis of other active compounds .
|
-
- HY-B2210
-
|
DIPA; Diisopropylamine dichloroacetate
|
Biochemical Assay Reagents
|
|
Diisopropylammonium dichloroacetate is an organic compound commonly used as a catalyst and ligand for organic reactions. It can promote various organic chemical reactions, such as olefin addition, carbonylation reaction and asymmetric catalytic reaction, etc. In addition, the compound is also widely used in the research of some medical fields, for example, in the application of anti-tumor therapy.
|
-
- HY-120967
-
|
|
Cell Assay Reagents
|
|
(2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98%, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
|
-
- HY-40228
-
|
(R)-2-Methylpropane-2-sulfinamide
|
Biochemical Assay Reagents
|
|
(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .
|
-
- HY-75920
-
|
|
Biochemical Assay Reagents
|
|
Inhoffen Lythgoe diol is an organic molecule commonly used in chiral selective reactions in organic synthesis. It can be used as a catalyst and a ligand, and has a wide range of applications in the preparation of nitrogen- and sulfur-containing natural products, pharmaceuticals, and material science. Inhoffen Lythgoe diol plays a very important role in the field of asymmetric synthesis. Although it has no direct medical application, it plays an important role in the production and research of many important chemicals.
|
-
- HY-24312
-
|
|
Biochemical Assay Reagents
|
|
AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.
|
-
- HY-158458
-
|
A2[3]G1F1(a1-3) glycan
|
Carbohydrates
|
|
A2[3]G1F1(α-1-3) glycan (A2[3]G1F1(a1-3) glycan) is an asymmetric Lewis X polysaccharide and N-glycan. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
|
-
- HY-W010507
-
|
Methyl (R)-(-)-3-hydroxybutyrate
|
Drug Delivery
|
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-Y0549
-
|
Diphenylmethane-α-carboxylic Acid
|
Biochemical Assay Reagents
|
|
Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .
|
-
- HY-W002530
-
|
|
Biochemical Assay Reagents
|
|
(1S,2R)-1-Aminoindan-2-ol is a chiral resolving agent. (1S,2R)-1-Aminoindan-2-ol efficiently resolves various racemic 2-arylalkanoic acids and precisely controls the stereostructure of the products in asymmetric syntheses. (1S,2R)-1-Aminoindan-2-ol can be used in the synthesis of HIV protease inhibitors .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4487
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H-Pro-Pro-Asp-NH2 is a potent and selective catalyst for asymmetric aldol reactions. H-Pro-Pro-Asp-NH2 catalyzes aldol reactions between acetone and several aldehydes .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99430
-
|
EM901; CC-93269
|
CD3
|
Inflammation/Immunology
Cancer
|
|
Alnuctamab (EM901) is a bispecific T-cell engager targeting BCMA and CD3, belonging to an asymmetric two-armed humanized IgG1 antibody. Alnuctamab can simultaneously bind to BCMA expressed on the surface of myeloma cells and CD3 molecules on the surface of T cells, recruiting T cells to kill tumors. Alnuctamab is used for the research of multiple myeloma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113216BS
-
|
|
|
Asymmetric-dimethylarginine-d6 (dihydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride .
|
-
-
- HY-113216AS
-
|
|
|
Asymmetric dimethylarginine-d7 (hydrochloride) is the deuterium labeled Asymmetric dimethylarginine hydrochloride .
|
-
-
- HY-113216S
-
|
|
|
Asymmetric dimethylarginine-d7 (hydrochloride hydrate) is the deuterium labeled Asymmetric dimethylarginine. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a num
|
-
-
- HY-D0839S1
-
|
|
|
Tetradecyltrimethylammonium-d29 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide) . Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure .
|
-
-
- HY-D0839S2
-
|
|
|
Tetradecyltrimethylammonium-d38 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide) . Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-142988
-
|
1S-2M-PC
|
|
Phospholipids
|
|
1-Stearoyl-2-myristoyl-sn-glycero-3-PC (1S-2M-PC) belongs to the class of asymmetric phospholipids. 1-Stearoyl-2-myristoyl-sn-glycero-3-PC is abundant in biological membranes .
|
-
- HY-W019833
-
|
PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
|
-
- HY-W440982
-
|
PC(18:0/18:1); 2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can be used for various biochemical studies .
|
-
- HY-W440957
-
|
PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
|
-
- HY-157672
-
|
|
|
Phospholipids
|
|
18:1-14:0 PC, an asymmetric phospholipid featuring an unsaturated acyl chain in the sn-1 position, can create a hydrophobic surface in mucus by functioning as a surfactant to impede bacterial penetrance, while also serving as a dietary source of choline.
|
-
- HY-W800734
-
|
MPPC; PC(14:0/16:0)
|
|
Phospholipids
|
|
1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
|
-
- HY-120967A
-
|
|
|
Phospholipids
|
|
(2S)-OMPT triethylamine, a chiral oxirane derivative, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
![[Ir(Cp-)Cl2]2](http://file.medchemexpress.eu/product_pic/hy-w018845.gif)
![A2[3]G1F1(α-1-3) glycan](http://file.medchemexpress.eu/product_pic/hy-158458.gif)
