2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR L861Q Recombinant Human Active Protein Kinase

EGFR L861Q Recombinant Human Active Protein Kinase 

Cat. No.: HY-E70708
Handling Instructions Technical Support

EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR L861Q Recombinant Human Active Protein Kinase is a recombinant EGFR L861Q protein that can be used to study EGFR L861Q-related functions.

For research use only. We do not sell to patients.

EGFR L861Q Recombinant Human Active Protein Kinase

EGFR L861Q Recombinant Human Active Protein Kinase Chemical Structure

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EGFR L861Q Recombinant Human Active Protein Kinase Related Antibodies

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Description

EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR L861Q Recombinant Human Active Protein Kinase is a recombinant EGFR L861Q protein that can be used to study EGFR L861Q-related functions[1].

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[EGFR L861Q Recombinant Human Active Protein Kinase]
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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EGFR L861Q Recombinant Human Active Protein Kinase Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR L861Q Recombinant Human Active Protein KinaseEGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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