2. Search Result
Search Result
Results for "

antifungal metabolite

" in MedChemExpress (MCE) Product Catalog:

62

Inhibitors & Agonists

1

Peptides

36

Natural
Products

6

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121362
    Evernic Acid

    		Bacterial Endogenous Metabolite Inflammation/Immunology Cancer
    Evernic Acid is a secondary metabolite generated by lichens, including Ramalina, Evernia, and Hypogymnia, and several studies have described its anticancer, antifungal, and antimicrobial effects. Neuroprotective and anti-inflammatory effects .
    Evernic Acid
  • HY-113219
    Hydroxyphenyllactic acid
    1 Publications Verification

    		 Endogenous Metabolite Fungal Infection
    Hydroxyphenyllactic acid is an antifungal metabolite.
    Hydroxyphenyllactic acid
  • HY-N10215
    Canadensolide

    		Fungal Endogenous Metabolite Infection
    Canadensolide is an antifungal metabolite of Penicillium canadense.
    Canadensolide
  • HY-124551
    Viridiol

    		Fungal Antibiotic Infection
    Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity .
    Viridiol
  • HY-N10288
    Eucalyptacid A

    		Fungal Endogenous Metabolite Infection
    Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .
    Eucalyptacid A
  • HY-N8499
    Sporothriolide

    		Fungal Infection
    Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo .
    Sporothriolide
  • HY-N16428
    Neoaspergillic acid

    NSC 356436

    		 Endogenous Metabolite Fungal Bacterial Infection Cancer
    Neoaspergillic acid (NSC 356436) (Compound 2) is a microbial secondary metabolite. Neoaspergillic acid can be isolated from the endophytic fungus Aspergillus sp. SPH2. Neoaspergillic acid has potent antifungal activity against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum. Neoaspergillic acid appears during the exponential phase of fungal growth. Neoaspergillic acid also antitumor and antibacterial effects .
    Neoaspergillic acid
  • HY-N16445
    Strevertene A

    (-)-Strevertene A

    		 Endogenous Metabolite Antibiotic Fungal Infection
    Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants .
    Strevertene A
  • HY-N16443
    Sporminarin A

    		Endogenous Metabolite Fungal Bacterial Infection
    Sporminarin A (Compound 1), a polyketide, is a microbial secondary metabolite. Sporminarin A can be isolated from the Sporormiella minimoides. Sporminarin A has significant antifungal activity against Aspergillus flavus with an MIC50 of 25  μg/mL. Sporminarin A also has antibacterial activity against Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 14053) .
    Sporminarin A
  • HY-N13993
    Aranorosinol A

    		Bacterial Fungal Infection
    Aranorosinol A is a secondary metabolite with weak antibacterial and antifungal properties .
    Aranorosinol A
  • HY-N10289
    Cytosporone C

    		Fungal Infection
    Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .
    Cytosporone C
  • HY-12772
    Hydroxy Itraconazole

    Itraconazole metabolite Hydroxy Itraconazole; R-63373

    		 Fungal Drug Metabolite Others
    Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole
  • HY-167831
    Vermistatin

    		Fungal Infection
    Vermistatin is a metabolite of the fungal strain Guignardia that has cytotoxic and antifungal activity .
    Vermistatin
  • HY-125723
    Echinocandin B

    SL 7810; A-30912 A

    		 Endogenous Metabolite Fungal Antibiotic Infection
    Echinocandin B (A 30912) is an antifungal antibiotic and is the secondary metabolite produced by Aspergillus nidulans .
    Echinocandin B
  • HY-I0903
    SCH 51048

    		Fungal Others
    SCH 51048 is a compound that can produce active metabolites, and its active metabolites have antifungal activity. Through metabolic studies and activity screening of the compound, metabolites and compounds with better activity were discovered.
    SCH 51048
  • HY-113219R
    Hydroxyphenyllactic acid (Standard)

    		Reference Standards Endogenous Metabolite Fungal Infection
    Hydroxyphenyllactic acid (Standard) is the analytical standard of Hydroxyphenyllactic acid. This product is intended for research and analytical applications. Hydroxyphenyllactic acid is an antifungal metabolite.
    Hydroxyphenyllactic acid (Standard)
  • HY-W654234
    Hydroxyphenyllactic acid-d3

    		Isotope-Labeled Compounds Endogenous Metabolite Fungal Infection
    Hydroxyphenyllactic acid-d3 is the deuterium labeled Hydroxyphenyllactic acid (HY-113219). Hydroxyphenyllactic acid is an antifungal metabolite .
    Hydroxyphenyllactic acid-d3
  • HY-W741557
    Griseofulvic Acid

    (±)-Griseofulvic acid

    		 Fungal Infection
    Griseofulvic acid is a metabolite of the antifungal Griseofulvin (HY-17583). It induces protein aggregation and tubulin polymerization in cell-free assays.
    Griseofulvic Acid
  • HY-113219S
    Hydroxyphenyllactic acid-d4

    		Isotope-Labeled Compounds Endogenous Metabolite Fungal Infection
    Hydroxyphenyllactic acid-d4 is the deuterium labeled Hydroxyphenyllactic acid (HY-113219). Hydroxyphenyllactic acid is an antifungal metabolite .
    Hydroxyphenyllactic acid-d4
  • HY-P10916
    Micafungin metabolite M1

    		Drug Metabolite Fungal Infection
    Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species .
    Micafungin metabolite M1
  • HY-N14066
    Ascochitine

    		Fungal Infection
    Ascochitine, a polyketide-derived secondary metabolite, is a selective antifungal agent. Ascochitine exhibits broad-spectrum phytotoxicity and antimicrobial activities .
    Ascochitine
  • HY-165017
    Etheroleic acid

    		Fungal Infection
    Etheroleic acid has antifungal activity against the powdery mildew B. graminis on the second leaves of barley seedlings. Etheroleic acid is a metabolite of Linolenic acid .
    Etheroleic acid
  • HY-N15097
    Dihydrocompactin

    		Antibiotic Fungal HMG-CoA Reductase (HMGCR) Infection Inflammation/Immunology
    Dihydrocompactin, an antifungal metabolite, is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase) from Penicillium citrinum .
    Dihydrocompactin
  • HY-118118
    Phlebiakauranol aldehyde

    		Fungal Infection
    Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .
    Phlebiakauranol aldehyde
  • HY-N12893
    Sclerodione

    		Fungal Lipase Infection
    Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM) .
    Sclerodione
  • HY-12772S3
    Hydroxy Itraconazole-d6

    R-63373-d6

    		 Isotope-Labeled Compounds Fungal Others
    Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole-d6
  • HY-12772S
    Hydroxy Itraconazole-d8

    R-63373-d8

    		 Fungal Infection
    Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole-d8
  • HY-12772A
    rel-Hydroxy Itraconazole

    rel-R-63373

    		 Drug Isomer Infection
    rel-Hydroxy Itraconazole (rel-R-63373) is a relative stereoisomer of Hydroxy Itraconazole. Hydroxy Itraconazole is the major active metabolite of the antifungal compound Itraconazole (HY-17514) .
    rel-Hydroxy Itraconazole
  • HY-N12260
    Benanomicin A

    		HIV Bacterial Infection
    Benanomicin A is a microbial metabolite and can be isolated from Actinomycetes.Benanomicin has antifungal activitya and inhibits HIV-1 viral infection in MT-4 cells .
    Benanomicin A
  • HY-129315
    Deacylketoconazole

    N-Deacetylketoconazole; R-39519

    		 Bacterial Fungal Infection
    Deacylketoconazole (N-Deacetylketoconazole; R-39519) is an orally active metabolite of Ketoconazole (HY-B0105). Deacylketoconazole exhibits antifungal and antibacterial activity. Deacylketoconazole is cytotoxic in rats hepatocyte .
    Deacylketoconazole
  • HY-N11528
    Eugenitol

    7-Noreugenitin

    		 Others Infection
    Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii) .
    Eugenitol
  • HY-100711
    Prodigiosin
    3 Publications Verification

    Prodigiosine; NSC47147

    		 Bacterial Apoptosis Wnt Fungal Parasite Infection Inflammation/Immunology Cancer
    Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
    Prodigiosin
  • HY-122785
    Fusapyrone

    		Fungal Infection
    Fusapyrone is a broad-spectrum antifungal metabolite first isolated from Fusarium species. It has been investigated for use in the control of postharvest crop diseases such as inhibiting the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes.
    Fusapyrone
  • HY-N10292
    Chaetosemin J

    		Fungal Endogenous Metabolite Infection
    Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM .
    Chaetosemin J
  • HY-N6027
    Cyclosporin C

    		Fungal Bacterial Infection
    Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C shows no activity against bacteria or yeasts .
    Cyclosporin C
  • HY-172565
    Posaconazole D-glucuronide

    SCH 56592 D-glucuronide

    		 Drug Metabolite UGT Infection
    Posaconazole D-glucuronide (SCH 56592 D-glucuronide) is a glucuronide metabolite of the antifungal agent Posaconazole (HY-17373). Posaconazole D-glucuronide can be formed in human liver microsomes catalyzed by UGT1A4 .
    Posaconazole D-glucuronide
  • HY-100711A
    Prodigiosin hydrochloride
    3 Publications Verification

    Prodigiosine hydrochloride

    		 Bacterial Apoptosis Fungal Wnt Parasite Infection Inflammation/Immunology Cancer
    Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
    Prodigiosin hydrochloride
  • HY-17011
    Croconazole

    		Fungal Metabolic Disease
    Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile .
    Croconazole
  • HY-125706
    1233B

    		Fungal Antibiotic Infection
    1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .
    1233B
  • HY-121178
    Deoxyviolacein

    		Bacterial Fungal Infection
    Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.
    Deoxyviolacein
  • HY-N6780
    Ophiobolin B

    		Fungal Infection
    Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement . The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL .
    Ophiobolin B
  • HY-136767
    Cladosporin

    		Antibiotic Fungal Bacterial Parasite DNA/RNA Synthesis Infection
    Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1) .
    Cladosporin
  • HY-N15653
    Heveadride

    		Endogenous Metabolite Fungal NF-κB Infection Cancer
    Heveadride is a fungal metabolite and an antifungal agent. Heveadride is active against various filamentous fungi and some human pathogenic yeasts. Heaveadride induces down-regulation of TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with an IC50 of 82.7 μM .
    Heveadride
  • HY-W016203
    Phenylpyruvic acid sodium

    Sodium phenylpyruvate

    		 Endogenous Metabolite PDI Infection Metabolic Disease
    Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .
    Phenylpyruvic acid sodium
  • HY-116637
    Tetrahydromagnolol

    Magnolignan

    		 Cannabinoid Receptor GPR55 Drug Metabolite Infection Neurological Disease Inflammation/Immunology
    Tetrahydromagnolol (Magnolignan), the main metabolite of Magnolol, is a potent and selective cannabinoidCB2 receptor agonist (EC50 =170 nM) and GPR55 antagonist. The Ki of Tetrahydromagnolol for CB2 is 416 nM, 20-fold higher than for the CB1 receptor. Magnolol shows antifungal, anti-inflammatory and analgesic effects .
    Tetrahydromagnolol
  • HY-N16394
    4-Hydroxyscytalone

    		Endogenous Metabolite Cancer
    4-Hydroxyscytalone (Compound 3) is a microbial secondary metabolite. 4-Hydroxyscytalone can be isolated from the oak fungus Diplodia corticola. 4-Hydroxyscytalone has toxicity against Artemia salina with a LC50 of 90.6 μ/mL, but no significant antifungal activity. 4-Hydroxyscytalone can be used for cancer therapy research .
    4-Hydroxyscytalone
  • HY-129548
    Prumycin

    		Antibiotic Infection
    Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .
    Prumycin
  • HY-129548A
    Prumycin di(hydrochloride)

    		Fungal Infection
    Prumycin dihydrochloride is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin dihydrochloride significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin dihydrochloride did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .
    Prumycin di(hydrochloride)
  • HY-N12231
    Carbazomycin B

    		Antibiotic Bacterial Lipoxygenase Infection Cancer
    Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µM sup>[2]sup>[3]sup>[4].
    Carbazomycin B
  • HY-W010435
    Sulcatone

    6-Methyl-5-hepten-2-one

    		 Endogenous Metabolite Fungal Parasite Adenosine Receptor Cytochrome P450 Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis .
    Sulcatone

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: