Search Result
Results for "
amine derivative
" in MedChemExpress (MCE) Product Catalog:
52
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W015302
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Orthanilic acid; 2-Aminobenzenesulphonic acid
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Drug Intermediate
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Others
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2-Aminobenzenesulfonic acid (Orthanilic acid) is an amine derivative. 2-Aminobenzenesulfonic can be used for the synthesis of other active compounds. 2-Aminobenzenesulfonic acid can be converted into Schiff base, and further used for the preparation of metal complexes .
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-
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- HY-Y1169
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4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
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Amino Acid Derivatives
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Others
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Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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- HY-W027595
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-
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- HY-D2027
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Fluorescent Dye
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Others
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ATTO 550 amine is an amine derivative of ATTO 550, the maximum excitation/emission wavelength: 554/576 nm.
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-
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- HY-D1928
-
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Fluorescent Dye
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Others
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ATTO 425 Amine is an amine derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
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-
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- HY-D2032
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Fluorescent Dye
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Others
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ATTO 514 amine is an amine derivative of ATTO 514, the maximum excitation/emission wavelength: 511/531 nm.
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-
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- HY-D2078
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Fluorescent Dye
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Others
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ATTO 665 amine is an amine derivative of ATTO 665, the maximum excitation/emission wavelength: 663/680 nm.
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-
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- HY-D2066
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Fluorescent Dye
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Others
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ATTO 680 amine is an amine derivative of ATTO 680, the maximum excitation/emission wavelength: 681/698 nm.
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-
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- HY-D1952
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Fluorescent Dye
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Others
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ATTO 594 Amine is an amine derivative of ATTO 594, the maximum excitation/emission wavelength: 603/626 nm.
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- HY-D2050
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Fluorescent Dye
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Others
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ATTO 532 amine is an amine derivative of ATTO 532, the maximum excitation/emission wavelength: 532/552 nm.
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- HY-D2005
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Fluorescent Dye
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Others
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ATTO 565 amine is an amine derivative of ATTO 565, the maximum excitation/emission wavelength: 564/590 nm.
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- HY-D1943
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Fluorescent Dye
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Others
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ATTO 590 Amine is an amine derivative of ATTO 590, the maximum excitation/emission wavelength: 594/622 nm.
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- HY-D2008
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Fluorescent Dye
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Others
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ATTO 488 amine is an amine derivative of ATTO 488, the maximum excitation/emission wavelength: 500/520 nm.
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-
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- HY-W052190
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Drug Derivative
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Others
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4-(4-chlorophenyl)thiazol-2-amine (Compound A) is the derivative of Aminothiazole (HY-12396) .
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-
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- HY-W007287
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Drug Intermediate
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Others
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5-Methoxyquinolin-8-amine is a synthetic intermediate that can be used to prepare N-phthaloyl amino acid derivatives .
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- HY-141261A
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Biochemical Assay Reagents
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Others
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Methyltetrazine-PEG4-amine hydrochloride is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine hydrochloride is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-141261
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Biochemical Assay Reagents
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Others
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Methyltetrazine-PEG4-amine is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-D1369
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Fluorescent Dye
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BDP R6G amine hydrochloride is a boronic dipyrromethene dye matched to the rhodamine 6G (R6G) channel. The fluorophore derivative contains an aliphatic amine group in the form of a salt. Amine groups can be conjugated to electrophiles. Amines can also be used for enzymatic transamination.
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- HY-D1665
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Fluorescent Dye
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Others
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BDP 558/568 amine is an amine derivative of BDP 558/568. BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. BDP 558/568 amine can be conjugated by means of reactions with various electrophiles .
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- HY-125924A
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Biochemical Assay Reagents
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Cancer
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DSPE-PEG-Amine, MW 20000 ammonium is an amine derivative of phospholipid polyethylene glycol, used for the synthesis of solid lipids and thermosensitive liposome nanoparticles for the delivery of anticancer agents .
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- HY-W007509
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5-Aminoindole
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Biochemical Assay Reagents
Drug Intermediate
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Others
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1H-Indol-5-amine (5-Aminoindole) is an organic compound containing an indole ring structure and belongs to the class of indole derivatives. 1H-Indol-5-amine can serve as a key intermediate for the synthesis of other active compounds .
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- HY-D1336
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Fluorescent Dye
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FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
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- HY-W440823B
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Liposome
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Cancer
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DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530). DSPE-PEG(2000)-amine can be used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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- HY-133883
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Fluorescent Dye
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Others
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Cyanine7.5 amine is a NIR fluorescent dye. Cyanine7.5 amine contains free amino group which can be used coupled with activated carboxylic acid derivatives.
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- HY-W025443
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GABA Receptor
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Others
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6-(4-Methoxyphenyl)pyridazin-3-amine is an aminopyridazine derivative, and can be used for the synthesis of SR 95103. SR 95103 is a selective and competitive GABA-A receptor antagonist .
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- HY-W013081
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- HY-125924
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DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) amine ammonium
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Liposome
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Others
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DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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- HY-W588728
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Biochemical Assay Reagents
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Others
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DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-W588736
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Biochemical Assay Reagents
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Others
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DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-D1919
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Fluorescent Dye
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Others
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ATTO 390 amine is a biotin derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm.
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- HY-169493
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- HY-D2494
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Fluorescent Dye
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Others
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Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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- HY-D2486
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Fluorescent Dye
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Others
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Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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- HY-D1852
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Fluorescent Dye
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Others
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Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D1939
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Fluorescent Dye
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Others
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ATTO 465 amine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 amine is an amine derivative of ATTO 465 and can be used to label proteins or antibodies.
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- HY-D1851
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Fluorescent Dye
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Others
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Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-114761
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Prostaglandin Receptor
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Cardiovascular Disease
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Prostaglandin F2α dimethyl amine is a Prostaglandin F2α (HY-12956) derivative. Prostaglandin F2α dimethyl amine is an antagonist for Prostaglandin F receptor (FP) . Prostaglandin F2α dimethyl amine blocks the cardiovascular responses induced by orexin and Arachidonic acid (HY-109590) .
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- HY-W440691
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Biochemical Assay Reagents
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Others
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Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 3400) can be used in drug delivery research .
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- HY-W440692
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Biochemical Assay Reagents
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Others
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Cholesterol-PEG-amine (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 5000) can be used in drug delivery research .
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- HY-135448
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Drug Derivative
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Neurological Disease
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25G-NBOMe hydrochloride is a derivative of 2,5-phenethylamines, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine .
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- HY-D1370
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Fluorescent Dye
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BDP TMR amine is a dye for the TAMRA channel. However, unlike original TAMRA, it has very good quantum yield and therefore high brightness. This derivative contains primary amine groups that can be conjugated to a variety of electrophiles. It can also participate in enzymatic transamination reactions.
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- HY-D0099
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Fluorescent Dye
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Others
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Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .
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- HY-118441
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-
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- HY-D1375
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Fluorescent Dye
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Others
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Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D1272
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Sulfo-Cyanine3 amine
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Fluorescent Dye
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Others
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Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-W1048843B
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4-Arm PEG-amine (MW 10000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 (MW 10000) (4-Arm PEG-amine (MW 10000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048843A
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 (MW 5000) (4-Arm PEG-amine (MW 5000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048519B
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4-Arm PEG-amine HCL salt (MW 20000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 HCl (MW 20000) (4-Arm PEG-amine HCL salt (MW 20000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048843C
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4-Arm PEG-amine (MW 20000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 (MW 20000) (4-Arm PEG-amine (MW 20000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048519C
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4-Arm PEG-amine HCL salt (MW 40000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 HCl (MW 40000) (4-Arm PEG-amine HCL salt (MW 40000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048519
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4-Arm PEG-amine HCL salt (MW 5000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 HCl (MW 5000) (4-Arm PEG-amine HCL salt (MW 5000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048843D
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4-Arm PEG-amine (MW 40000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 (MW 40000) (4-Arm PEG-amine (MW 40000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048519A
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4-Arm PEG-amine HCL salt (MW 10000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 HCl (MW 10000) (4-Arm PEG-amine HCL salt (MW 10000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-174900
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Azido-PEG13-NH2
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Biochemical Assay Reagents
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Others
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Azido-PEG13-amine (Azido-PEG13-NH2) is a PEG derivative that can be used for drug delivery and other research. Azido-PEG13-amine is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. It can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-W010778
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Biochemical Assay Reagents
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Others
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N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-quinazolin-4-amine is a quinazoline derivative that has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.
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- HY-D1863
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Fluorescent Dye
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Others
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sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-W076740
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8-Bromo-9H-purin-6-amine
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DNA/RNA Synthesis
Biochemical Assay Reagents
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Others
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8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium .
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- HY-174916
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Biochemical Assay Reagents
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Others
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Amine-PEG1-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 1 PEG unit, and an amino group (Amine). Desthiobiotin is a biotin analog that has a weak but reversible binding ability to streptavidin or avidin. The amino group is able to react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-D0799
-
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Fluorescent Dye
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Others
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Sulfo-NHS-LC-Biotin sodium is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
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- HY-D0799A
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Fluorescent Dye
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Others
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Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
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- HY-124332
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- HY-120858
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- HY-123067
-
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Fluorescent Dye
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Metabolic Disease
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NBD-Fructose is a fluorescent derivative of Fructose (HY-N0395) that is formed by coupling NBD-chloride with the amine group of amino fructose (EX/Em=472/538 nm) .
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- HY-D1041
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ICG NHS ester
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Fluorescent Dye
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Cancer
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ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
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- HY-D2163
-
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Fluorescent Dye
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Others
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AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-W1048843
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4-Arm PEG-amine (MW 2000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-NH2 (MW 2000) (4-Arm PEG-Amine (MW 2000)) is a PEG derivative that can be used for drug delivery research .
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- HY-W1048525B
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8-Arm PEG-amine (MW 40000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 40000) (8-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048526
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8-Arm PEG-amine HCL salt (MW 5000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 5000) (8-Arm PEG-Amine (MW 5000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048526C
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8-Arm PEG-amine HCL salt (MW 10000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 10000) (8-Arm PEG-Amine (MW 10000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048525C
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8-Arm PEG-amine (MW 10000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 10000) (8-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048526B
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8-Arm PEG-amine HCL salt (MW 40000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 40000) (8-Arm PEG-Amine (MW 40000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048526A
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8-Arm PEG-amine HCL salt (MW 20000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 20000) (8-Arm PEG-Amine (MW 20000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048525
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8-Arm PEG-amine (MW 5000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 5000) (8-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048525A
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8-Arm PEG-amine (MW 20000)
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Biochemical Assay Reagents
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Others
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8-Arm PEG-NH2 (MW 20000) (8-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-D0029
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5(6)-AFM; Fluoresceinamine mixed isomers
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Fluorescent Dye
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Others
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5(6)-Aminofluorescein (5(6)-AFM) is a a precursor for synthesis of 5(6)-FITC (HY-15941). 5(6)-FITC is an amine-reactive derivative of fluorescein dye.
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- HY-W1048511
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2-Arm PEG-amine (MW 5000)
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Biochemical Assay Reagents
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Others
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2-Arm PEG-NH2 (MW 5000) (2-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
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- HY-W1048511A
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2-Arm PEG-amine (MW 20000)
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Biochemical Assay Reagents
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Others
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2-Arm PEG-NH2 (MW 20000) (2-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
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- HY-W1048511C
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2-Arm PEG-amine (MW 10000)
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Biochemical Assay Reagents
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Others
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2-Arm PEG-NH2 (MW 10000) (2-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
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- HY-140535
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Biochemical Assay Reagents
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Others
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Boc-NH-Bis(acid-PEG1-m) is a PEG derivative contains carboxylic acid moieties. Boc-NH-Bis(acid-PEG1-m) can be conjugated with amine containing molecule .
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- HY-W324458
-
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Fluorescent Dye
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Others
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MCA succinimidyl ester is a derivative of MCA (HY-W027544). MCA succinimidyl ester has succinimidyl ester can react selectively with amines. MCA succinimidyl ester can be used as peptide substrate for fluorescence resonance energy transfer .
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- HY-W1048511B
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2-Arm PEG-amine (MW 40000)
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Biochemical Assay Reagents
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Others
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2-Arm PEG-NH2 (MW 40000) (2-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
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- HY-Y1636
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- HY-D1757
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LYen; PAsp- LY
|
Fluorescent Dye
|
Others
|
Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).
|
-
- HY-P2292
-
|
Bacterial
Fungal
|
Infection
|
Omiganan, FITC labeled is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines .
|
-
- HY-Y1092
-
|
Biochemical Assay Reagents
Adenylate Cyclase
|
Others
|
N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
-
- HY-32813
-
3-Iodopyridin-2-amine
|
Biochemical Assay Reagents
|
Others
|
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis .
|
-
- HY-114346A
-
|
Fluorescent Dye
|
Others
|
ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.
|
-
- HY-174932
-
|
Biochemical Assay Reagents
|
Others
|
Amino-PEG18-t-butyl ester is a PEG derivative consisting of t-butyl ester, PEG unit and an amino group (Amine). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W1049075A
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075C
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075B
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075E
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075D
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075H
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W708033
-
|
5-HT Receptor
|
Neurological Disease
|
25E-NBOMe hydrochloride is a derivative of 2C-E having an N-(2-methoxybenzyl) addition at the amine. 25E-NBOMe hydrochloride is a selective /b>5-HT2A receptor agonist.
|
-
- HY-174929
-
DBCO-PEG-NH2 (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Amine (MW 3400) (DBCO-PEG-NH2 (MW 3400)) is a PEG derivative consisting of DBCO, PEG units, and an amino group. The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds. DBCO-PEG-Amine (MW 3400) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-174929A
-
DBCO-PEG-NH2 (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Amine (MW 5000) (DBCO-PEG-NH2 (MW 5000)) is a PEG derivative consisting of DBCO, PEG units, and an amino group. The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds. DBCO-PEG-Amine (MW 5000) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-D1085
-
|
Fluorescent Dye
|
Others
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-Y0470
-
Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride
|
Monoamine Oxidase
|
Cardiovascular Disease
Inflammation/Immunology
Endocrinology
|
Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles .
|
-
- HY-15941
-
Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
|
Fluorescent Dye
|
Others
|
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
|
-
- HY-W013081S
-
-
- HY-Y1092R
-
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
N,N-Dicyclohexylcarbodiimide(DCC) (Standard) is the analytical standard of N,N-Dicyclohexylcarbodiimide(DCC). This product is intended for research and analytical applications. N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
-
- HY-164076
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-Epoxide is an activated polyethylene glycol (mPEG) derivative, which is achieved by converting the hydroxyl groups of mPEG into reactive epoxy groups. mPEG-Epoxide is a mild PEGylation reagent that reacts with amino groups in peptides and proteins to form stable secondary amine bonds. mPEG-Epoxide can be used in protein engineering and biomaterials research .
|
-
- HY-Y1636S1
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH . Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
|
-
- HY-133053
-
Hydroxy-PEG8-acid
|
Biochemical Assay Reagents
|
Others
|
HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators to form a stable amide bond .
|
-
- HY-133513
-
(±)-H3L28
|
Drug Derivative
|
Cancer
|
(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) .
|
-
- HY-W1048549H
-
HOOC-PEG-Thiol (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 1000) (HOOC-PEG-Thiol (MW 1000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The reaction of the carboxyl group allows the amine or hydroxyl group to be converted into a free thiol with a linear PEG linkage. The generated thiol group can be used to modify the surface of gold nanoparticles or participate in other PEGylation reactions. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-W1048549J
-
HOOC-PEG-Thiol (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 40000) (HOOC-PEG-Thiol (MW 40000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The reaction of the carboxyl group allows the amine or hydroxyl group to be converted into a free thiol with a linear PEG linkage. The generated thiol group can be used to modify the surface of gold nanoparticles or participate in other PEGylation reactions. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-WAA0302
-
|
Biochemical Assay Reagents
|
Others
|
1,4-Bis-Boc-1,4,7-triazaheptane is a PEG derivative containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W1048549A
-
HOOC-PEG-Thiol (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 2000) (HOOC-PEG-Thiol (MW 2000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-W1048549B
-
HOOC-PEG-Thiol (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 3400) (HOOC-PEG-Thiol (MW 3400)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-W1048549C
-
HOOC-PEG-Thiol (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 5000) (HOOC-PEG-Thiol (MW 5000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-Y0470R
-
Aminourea hydrochloride (Standard); Hydrazinecarboxamide hydrochloride (Standard)
|
Antibiotic
Reference Standards
|
Inflammation/Immunology
Cancer
|
Semicarbazide (hydrochloride) (Standard) is the analytical standard of Semicarbazide (hydrochloride). This product is intended for research and analytical applications. Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles .
|
-
- HY-W1048549E
-
HOOC-PEG-Thiol (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 20000) (HOOC-PEG-Thiol (MW 20000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-121920
-
|
5-HT Receptor
|
Neurological Disease
|
25C-NBOH hydrochloride is a derivative of 2C-C having an N-(2-hydroxybenzyl) addition at the amine and is a potent agonist of 5-HT receptors that shows selectivity for 5-HT2A over 5-HT2C (EC50s = ~ 0.40 and 15 nM, respectively) .
|
-
- HY-W1048549D
-
HOOC-PEG-Thiol (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
HOOC-PEG-SH (MW 10000) (HOOC-PEG-Thiol (MW 10000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
|
-
- HY-W128798
-
|
5-HT Receptor
|
Neurological Disease
|
Sulfabenz (Compound 9) is an amine-substituted N1-phenylsulfonyl indole derivative. Sulfabenz has binding activity to human 5-HT6 serotonin receptor (Ki: 200 nM). Sulfabenz can be used to study the ligand binding mechanism of 5-HT6 receptor and 5-HT6 receptor-related neurological diseases .
|
-
- HY-Y1169S1
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH . Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-D1848
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D1848A
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-Y1636S
-
-
- HY-W451406B
-
|
Biochemical Assay Reagents
|
Others
|
NH2-PEG-NH2 (MW 1000) is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
|
-
- HY-W451406C
-
|
Biochemical Assay Reagents
|
Others
|
NH2-PEG-NH2 (MW 2000) is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
|
-
- HY-D1653
-
|
Reactive Oxygen Species (ROS)
|
Others
|
BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.
|
-
- HY-150014
-
|
Others
|
Others
|
AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
|
-
- HY-W451406D
-
|
Biochemical Assay Reagents
|
Others
|
NH2-PEG-NH2 (MW 10000) is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
|
-
- HY-W451406A
-
|
Biochemical Assay Reagents
|
Others
|
NH2-PEG-NH2 (MW:5000) is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
|
-
- HY-130695
-
|
ADC Linker
|
Cancer
|
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N-(Amino-PEG5)-N-bis(PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs) .
|
-
- HY-Y1169S2
-
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3; Fmoc-L-Asp(OtBu)-OH-d3
|
Isotope-Labeled Compounds
Amino Acid Derivatives
|
Others
|
Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-131025
-
JF585, SE; JF585, NHS
|
Fluorescent Dye
|
Others
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-108239
-
|
Histone Methyltransferase
Autophagy
|
Cancer
|
BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells .
|
-
- HY-10587
-
BIX-01294
Maximum Cited Publications
23 Publications Verification
|
Histone Methyltransferase
Autophagy
|
Cancer
|
BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells .
|
-
- HY-16094
-
BW 467C60
|
Adrenergic Receptor
|
Neurological Disease
|
Bethanidine sulfate and its ortho-chloro derivative (BW 392C60) are potent adrenergic neurone blockers with sympathomimetic effects similar to bretylium and guanethidine in various animal models, particularly in cats. They inhibit the release of noradrenaline during nerve stimulation and enhance smooth muscle responses to adrenaline and noradrenaline. Bethanidine sulfate increases pressor responses to tyramine, though this effect diminishes with higher doses. Unlike guanethidine, Bethanidine sulfate does not deplete pressor amine content in the iris of cats post-administration. It also briefly inhibits autonomic cholinergic mechanisms and causes temporary neuromuscular paralysis in large doses, contrasting with its prolonged adrenergic neurone blocking effects .
|
-
- HY-D2772
-
|
Biochemical Assay Reagents
|
Others
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-151833
-
|
ADC Linker
|
Others
|
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D2027
-
|
Fluorescent Dyes/Probes
|
ATTO 550 amine is an amine derivative of ATTO 550, the maximum excitation/emission wavelength: 554/576 nm.
|
-
- HY-D1928
-
|
Fluorescent Dyes/Probes
|
ATTO 425 Amine is an amine derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D2032
-
|
Fluorescent Dyes/Probes
|
ATTO 514 amine is an amine derivative of ATTO 514, the maximum excitation/emission wavelength: 511/531 nm.
|
-
- HY-D2078
-
|
Fluorescent Dyes/Probes
|
ATTO 665 amine is an amine derivative of ATTO 665, the maximum excitation/emission wavelength: 663/680 nm.
|
-
- HY-D2066
-
|
Fluorescent Dyes/Probes
|
ATTO 680 amine is an amine derivative of ATTO 680, the maximum excitation/emission wavelength: 681/698 nm.
|
-
- HY-D1952
-
|
Fluorescent Dyes/Probes
|
ATTO 594 Amine is an amine derivative of ATTO 594, the maximum excitation/emission wavelength: 603/626 nm.
|
-
- HY-D2050
-
|
Fluorescent Dyes/Probes
|
ATTO 532 amine is an amine derivative of ATTO 532, the maximum excitation/emission wavelength: 532/552 nm.
|
-
- HY-D2005
-
|
Fluorescent Dyes/Probes
|
ATTO 565 amine is an amine derivative of ATTO 565, the maximum excitation/emission wavelength: 564/590 nm.
|
-
- HY-D1943
-
|
Fluorescent Dyes/Probes
|
ATTO 590 Amine is an amine derivative of ATTO 590, the maximum excitation/emission wavelength: 594/622 nm.
|
-
- HY-D2008
-
|
Fluorescent Dyes/Probes
|
ATTO 488 amine is an amine derivative of ATTO 488, the maximum excitation/emission wavelength: 500/520 nm.
|
-
- HY-D1369
-
|
Fluorescent Dyes/Probes
|
BDP R6G amine hydrochloride is a boronic dipyrromethene dye matched to the rhodamine 6G (R6G) channel. The fluorophore derivative contains an aliphatic amine group in the form of a salt. Amine groups can be conjugated to electrophiles. Amines can also be used for enzymatic transamination.
|
-
- HY-D1665
-
|
Fluorescent Dyes/Probes
|
BDP 558/568 amine is an amine derivative of BDP 558/568. BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. BDP 558/568 amine can be conjugated by means of reactions with various electrophiles .
|
-
- HY-D1336
-
|
Fluorescent Dyes/Probes
|
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
|
-
- HY-133883
-
|
Fluorescent Dyes/Probes
|
Cyanine7.5 amine is a NIR fluorescent dye. Cyanine7.5 amine contains free amino group which can be used coupled with activated carboxylic acid derivatives.
|
-
- HY-D1919
-
|
Fluorescent Dyes/Probes
|
ATTO 390 amine is a biotin derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm.
|
-
- HY-D2494
-
|
Fluorescent Dyes/Probes
|
Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D2486
-
|
Fluorescent Dyes/Probes
|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D1852
-
|
Fluorescent Dyes/Probes
|
Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1939
-
|
Fluorescent Dyes/Probes
|
ATTO 465 amine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 amine is an amine derivative of ATTO 465 and can be used to label proteins or antibodies.
|
-
- HY-D1851
-
|
Fluorescent Dyes/Probes
|
Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1370
-
|
Fluorescent Dyes/Probes
|
BDP TMR amine is a dye for the TAMRA channel. However, unlike original TAMRA, it has very good quantum yield and therefore high brightness. This derivative contains primary amine groups that can be conjugated to a variety of electrophiles. It can also participate in enzymatic transamination reactions.
|
-
- HY-D0099
-
|
Fluorescent Dyes/Probes
|
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .
|
-
- HY-D1375
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1272
-
Sulfo-Cyanine3 amine
|
Fluorescent Dyes/Probes
|
Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1863
-
|
Fluorescent Dyes/Probes
|
sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D0799A
-
|
Dyes
|
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
|
-
- HY-D1041
-
ICG NHS ester
|
Fluorescent Dyes/Probes
|
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
- HY-D2163
-
|
Fluorescent Dyes/Probes
|
AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D0029
-
5(6)-AFM; Fluoresceinamine mixed isomers
|
Fluorescent Dyes/Probes
|
5(6)-Aminofluorescein (5(6)-AFM) is a a precursor for synthesis of 5(6)-FITC (HY-15941). 5(6)-FITC is an amine-reactive derivative of fluorescein dye.
|
-
- HY-W324458
-
|
Fluorescent Dyes/Probes
|
MCA succinimidyl ester is a derivative of MCA (HY-W027544). MCA succinimidyl ester has succinimidyl ester can react selectively with amines. MCA succinimidyl ester can be used as peptide substrate for fluorescence resonance energy transfer .
|
-
- HY-D1757
-
LYen; PAsp- LY
|
Fluorescent Dyes/Probes
|
Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).
|
-
- HY-114346A
-
|
Dyes
|
ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.
|
-
- HY-D1085
-
|
Fluorescent Dyes/Probes
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-15941
-
Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
|
Fluorescent Dyes/Probes
|
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
|
-
- HY-D1848
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D1848A
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D1653
-
|
Fluorescent Dyes/Probes
|
BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.
|
-
- HY-131025
-
JF585, SE; JF585, NHS
|
Fluorescent Dyes/Probes
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D2772
-
|
Fluorescent Dyes/Probes
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
Cat. No. |
Product Name |
Type |
-
- HY-W007509
-
5-Aminoindole
|
Biochemical Assay Reagents
|
1H-Indol-5-amine (5-Aminoindole) is an organic compound containing an indole ring structure and belongs to the class of indole derivatives. 1H-Indol-5-amine can serve as a key intermediate for the synthesis of other active compounds .
|
-
- HY-W013081
-
-
- HY-125924
-
DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) amine ammonium
|
Drug Delivery
|
DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
|
-
- HY-W1048843B
-
4-Arm PEG-amine (MW 10000)
|
Drug Delivery
|
4-Arm PEG-NH2 (MW 10000) (4-Arm PEG-amine (MW 10000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-125924A
-
|
Drug Delivery
|
DSPE-PEG-Amine, MW 20000 ammonium is an amine derivative of phospholipid polyethylene glycol, used for the synthesis of solid lipids and thermosensitive liposome nanoparticles for the delivery of anticancer agents .
|
-
- HY-W588728
-
|
Drug Delivery
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W588736
-
|
Drug Delivery
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W440691
-
|
Drug Delivery
|
Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 3400) can be used in drug delivery research .
|
-
- HY-W440692
-
|
Drug Delivery
|
Cholesterol-PEG-amine (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 5000) can be used in drug delivery research .
|
-
- HY-W1048843A
-
|
Drug Delivery
|
4-Arm PEG-NH2 (MW 5000) (4-Arm PEG-amine (MW 5000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048519B
-
4-Arm PEG-amine HCL salt (MW 20000)
|
Drug Delivery
|
4-Arm PEG-NH2 HCl (MW 20000) (4-Arm PEG-amine HCL salt (MW 20000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048843C
-
4-Arm PEG-amine (MW 20000)
|
Drug Delivery
|
4-Arm PEG-NH2 (MW 20000) (4-Arm PEG-amine (MW 20000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048519C
-
4-Arm PEG-amine HCL salt (MW 40000)
|
Drug Delivery
|
4-Arm PEG-NH2 HCl (MW 40000) (4-Arm PEG-amine HCL salt (MW 40000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048519
-
4-Arm PEG-amine HCL salt (MW 5000)
|
Drug Delivery
|
4-Arm PEG-NH2 HCl (MW 5000) (4-Arm PEG-amine HCL salt (MW 5000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048843D
-
4-Arm PEG-amine (MW 40000)
|
Drug Delivery
|
4-Arm PEG-NH2 (MW 40000) (4-Arm PEG-amine (MW 40000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048519A
-
4-Arm PEG-amine HCL salt (MW 10000)
|
Drug Delivery
|
4-Arm PEG-NH2 HCl (MW 10000) (4-Arm PEG-amine HCL salt (MW 10000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-174900
-
Azido-PEG13-NH2
|
Drug Delivery
|
Azido-PEG13-amine (Azido-PEG13-NH2) is a PEG derivative that can be used for drug delivery and other research. Azido-PEG13-amine is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. It can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
|
-
- HY-W076740
-
8-Bromo-9H-purin-6-amine
|
Gene Sequencing and Synthesis
|
8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium .
|
-
- HY-174916
-
|
Drug Delivery
|
Amine-PEG1-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 1 PEG unit, and an amino group (Amine). Desthiobiotin is a biotin analog that has a weak but reversible binding ability to streptavidin or avidin. The amino group is able to react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W1048843
-
4-Arm PEG-amine (MW 2000)
|
Drug Delivery
|
4-Arm PEG-NH2 (MW 2000) (4-Arm PEG-Amine (MW 2000)) is a PEG derivative that can be used for drug delivery research .
|
-
- HY-W1048525B
-
8-Arm PEG-amine (MW 40000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 40000) (8-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526
-
8-Arm PEG-amine HCL salt (MW 5000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 5000) (8-Arm PEG-Amine (MW 5000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526C
-
8-Arm PEG-amine HCL salt (MW 10000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 10000) (8-Arm PEG-Amine (MW 10000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048525C
-
8-Arm PEG-amine (MW 10000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 10000) (8-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526B
-
8-Arm PEG-amine HCL salt (MW 40000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 40000) (8-Arm PEG-Amine (MW 40000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526A
-
8-Arm PEG-amine HCL salt (MW 20000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 20000) (8-Arm PEG-Amine (MW 20000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048525
-
8-Arm PEG-amine (MW 5000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 5000) (8-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048525A
-
8-Arm PEG-amine (MW 20000)
|
Drug Delivery
|
8-Arm PEG-NH2 (MW 20000) (8-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048511
-
2-Arm PEG-amine (MW 5000)
|
Drug Delivery
|
2-Arm PEG-NH2 (MW 5000) (2-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048511A
-
2-Arm PEG-amine (MW 20000)
|
Drug Delivery
|
2-Arm PEG-NH2 (MW 20000) (2-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048511C
-
2-Arm PEG-amine (MW 10000)
|
Drug Delivery
|
2-Arm PEG-NH2 (MW 10000) (2-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048511B
-
2-Arm PEG-amine (MW 40000)
|
Drug Delivery
|
2-Arm PEG-NH2 (MW 40000) (2-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-Y1092
-
|
Biochemical Assay Reagents
|
N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
-
- HY-32813
-
3-Iodopyridin-2-amine
|
Biochemical Assay Reagents
|
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis .
|
-
- HY-174932
-
|
Drug Delivery
|
Amino-PEG18-t-butyl ester is a PEG derivative consisting of t-butyl ester, PEG unit and an amino group (Amine). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W1049075A
-
|
Drug Delivery
|
mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075C
-
|
Drug Delivery
|
mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075B
-
|
Drug Delivery
|
mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075E
-
|
Drug Delivery
|
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075D
-
|
Drug Delivery
|
mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075H
-
|
Drug Delivery
|
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075
-
|
Drug Delivery
|
mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-174929
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DBCO-PEG-NH2 (MW 3400)
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Drug Delivery
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DBCO-PEG-Amine (MW 3400) (DBCO-PEG-NH2 (MW 3400)) is a PEG derivative consisting of DBCO, PEG units, and an amino group. The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds. DBCO-PEG-Amine (MW 3400) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-174929A
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DBCO-PEG-NH2 (MW 5000)
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Drug Delivery
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DBCO-PEG-Amine (MW 5000) (DBCO-PEG-NH2 (MW 5000)) is a PEG derivative consisting of DBCO, PEG units, and an amino group. The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds. DBCO-PEG-Amine (MW 5000) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-Y1092R
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Biochemical Assay Reagents
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N,N-Dicyclohexylcarbodiimide(DCC) (Standard) is the analytical standard of N,N-Dicyclohexylcarbodiimide(DCC). This product is intended for research and analytical applications. N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
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- HY-W1048549H
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HOOC-PEG-Thiol (MW 1000)
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Drug Delivery
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HOOC-PEG-SH (MW 1000) (HOOC-PEG-Thiol (MW 1000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The reaction of the carboxyl group allows the amine or hydroxyl group to be converted into a free thiol with a linear PEG linkage. The generated thiol group can be used to modify the surface of gold nanoparticles or participate in other PEGylation reactions. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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- HY-W1048549J
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HOOC-PEG-Thiol (MW 40000)
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Drug Delivery
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HOOC-PEG-SH (MW 40000) (HOOC-PEG-Thiol (MW 40000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The reaction of the carboxyl group allows the amine or hydroxyl group to be converted into a free thiol with a linear PEG linkage. The generated thiol group can be used to modify the surface of gold nanoparticles or participate in other PEGylation reactions. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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- HY-W1048549A
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HOOC-PEG-Thiol (MW 2000)
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Drug Delivery
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HOOC-PEG-SH (MW 2000) (HOOC-PEG-Thiol (MW 2000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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- HY-W1048549B
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HOOC-PEG-Thiol (MW 3400)
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Drug Delivery
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HOOC-PEG-SH (MW 3400) (HOOC-PEG-Thiol (MW 3400)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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- HY-W1048549C
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HOOC-PEG-Thiol (MW 5000)
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Drug Delivery
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HOOC-PEG-SH (MW 5000) (HOOC-PEG-Thiol (MW 5000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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- HY-W1048549E
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HOOC-PEG-Thiol (MW 20000)
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Drug Delivery
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HOOC-PEG-SH (MW 20000) (HOOC-PEG-Thiol (MW 20000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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- HY-W1048549D
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HOOC-PEG-Thiol (MW 10000)
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Drug Delivery
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HOOC-PEG-SH (MW 10000) (HOOC-PEG-Thiol (MW 10000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-Y1169
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4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
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Amino Acid Derivatives
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Others
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Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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- HY-Y1636
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- HY-P2292
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Bacterial
Fungal
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Infection
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Omiganan, FITC labeled is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-W013081S
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Fmoc-Gln(Trt)-OH- 13C5, 15N2 is the 13C-labeled and 15N-labeled Fmoc-Gln(Trt)-OH (HY-W013081). Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc .
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- HY-Y1636S1
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Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH . Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
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- HY-Y1169S1
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Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH . Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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- HY-Y1636S
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Fmoc-Arg(Pbf)-OH- 13C6, 15N4 is the 13C-labeled and 15N-labeled Fmoc-Arg(Pbf)-OH (HY-Y1636). Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
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- HY-Y1169S2
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Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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Cat. No. |
Product Name |
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Classification |
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- HY-141261
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PROTAC Synthesis
Tetrazine
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Methyltetrazine-PEG4-amine is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-151833
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Tetrazine
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Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No. |
Product Name |
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Classification |
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- HY-125924
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DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) amine ammonium
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Pegylated Lipids
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DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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