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  4. Methyltetrazine-PEG4-amine hydrochloride

Methyltetrazine-PEG4-amine hydrochloride is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine hydrochloride is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

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Methyltetrazine-PEG4-amine hydrochloride

Methyltetrazine-PEG4-amine hydrochloride Chemical Structure

CAS No. : 2245150-18-7

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Based on 1 publication(s) in Google Scholar

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Methyltetrazine-PEG4-amine hydrochloride Related Antibodies

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Description

Methyltetrazine-PEG4-amine hydrochloride is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine hydrochloride is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups[1].

Molecular Weight

399.87

Formula

C17H26ClN5O4
CAS No.
Appearance

Solid

SMILES

NCCOCCOCCOCCOC1=CC=C(C=C1)C2=NN=C(C)N=N2.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (250.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5008 mL 12.5041 mL 25.0081 mL
5 mM 0.5002 mL 2.5008 mL 5.0016 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5008 mL 12.5041 mL 25.0081 mL 62.5203 mL
5 mM 0.5002 mL 2.5008 mL 5.0016 mL 12.5041 mL
10 mM 0.2501 mL 1.2504 mL 2.5008 mL 6.2520 mL
15 mM 0.1667 mL 0.8336 mL 1.6672 mL 4.1680 mL
20 mM 0.1250 mL 0.6252 mL 1.2504 mL 3.1260 mL
25 mM 0.1000 mL 0.5002 mL 1.0003 mL 2.5008 mL
30 mM 0.0834 mL 0.4168 mL 0.8336 mL 2.0840 mL
40 mM 0.0625 mL 0.3126 mL 0.6252 mL 1.5630 mL
50 mM 0.0500 mL 0.2501 mL 0.5002 mL 1.2504 mL
60 mM 0.0417 mL 0.2084 mL 0.4168 mL 1.0420 mL
80 mM 0.0313 mL 0.1563 mL 0.3126 mL 0.7815 mL
100 mM 0.0250 mL 0.1250 mL 0.2501 mL 0.6252 mL
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Methyltetrazine-PEG4-amine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyltetrazine-PEG4-amine2245150-18-7Biochemical Assay ReagentsInhibitorinhibitorinhibit

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