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Results for "

acylhydrazone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (7) DNA/RNA Synthesis (1) Fungal (2) PROTAC Linkers (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (2) Infection (3) Inflammation/Immunology (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-41541

Tetraethylene glycol monotosylate Tos-PEG4	ADC Linker PROTAC Linkers	Cancer
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W1049075C

mPEG-pALD (MW 20000)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W514721

D13	Fungal	Infection Inflammation/Immunology
D13, an Acylhydrazones derivative, possesses antifungal activity. D13 is effective against murine sporotrichosis .

HY-156195

BHBM	Fungal	Infection
BHBM (compound 1) is an aromatic acylhydrazone antifungal agent with high bactericidal activity against Cryptococcus neoformans .

HY-179059

Anti-MRSA agent 40	Bacterial Reactive Oxygen Species (ROS)	Infection
Anti-MRSA agent 40 (Compound 7-8) is a potent agent against Methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 40 exhibits significant antibacterial activity against MRSA2 and S. aureus ATCC 29213, with its MIC values being 1 μg/mL. Anti-MRSA agent 40 causes depolarization of the cell membrane, damages membrane integrity, and simultaneously increases the level of ROS within MRSA2, ultimately leading to cell lysis and death. Anti-MRSA agent 40 exhibits extremely low cytotoxicity, and there is almost no risk of hemolysis at the effective antibacterial concentration. Anti-MRSA agent 40 shows significant efficacy in the MRSA2 skin abscess model. Anti-MRSA agent 40 can be used for research on anti-MRSA infections .

HY-W1049075A

mPEG-pALD (MW 5000)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075B

mPEG-pALD (MW 10000)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075E

mPEG-pALD (MW 2000)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075D

mPEG-pALD (MW 40000)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075H

mPEG-pALD (MW 3400)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075

mPEG-pALD (MW 1000)	Biochemical Assay Reagents	Others
mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-161617

LASSBio-2052	DNA/RNA Synthesis Apoptosis	Cancer
LASSBio-2052 is a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC). LASSBio-2052 inhibits HCC cells HepG2 and Hep3B, with IC₅₀ of 18 and 41 μM. LASSBio-2052 arrests the cell cycle at G2/M phase, through downregulation of FOXM1. LASSBio-2052 induces apoptosis in HCC cells .

Cat. No.	Product Name	Type

HY-W1049075C

mPEG-pALD (MW 20000)	Drug Delivery
mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 20000)

Drug Delivery

mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075A

mPEG-pALD (MW 5000)	Drug Delivery
mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 5000)

Drug Delivery

mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075B

mPEG-pALD (MW 10000)	Drug Delivery
mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 10000)

Drug Delivery

mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075E

mPEG-pALD (MW 2000)	Drug Delivery
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 2000)

Drug Delivery

mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075D

mPEG-pALD (MW 40000)	Drug Delivery
mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 40000)

Drug Delivery

mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075H

mPEG-pALD (MW 3400)	Drug Delivery
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 3400)

Drug Delivery

mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075

mPEG-pALD (MW 1000)	Drug Delivery
mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

mPEG-pALD (MW 1000)

Drug Delivery

mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

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