2. Anti-infection NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Bacterial Reactive Oxygen Species (ROS)
  4. Anti-MRSA agent 40

Anti-MRSA agent 40 (Compound 7-8) is a potent agent against Methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 40 exhibits significant antibacterial activity against MRSA2 and S. aureus ATCC 29213, with its MIC values being 1 μg/mL. Anti-MRSA agent 40 causes depolarization of the cell membrane, damages membrane integrity, and simultaneously increases the level of ROS within MRSA2, ultimately leading to cell lysis and death. Anti-MRSA agent 40 exhibits extremely low cytotoxicity, and there is almost no risk of hemolysis at the effective antibacterial concentration. Anti-MRSA agent 40 shows significant efficacy in the MRSA2 skin abscess model. Anti-MRSA agent 40 can be used for research on anti-MRSA infections.

For research use only. We do not sell to patients.

Anti-MRSA agent 40

Anti-MRSA agent 40 Chemical Structure

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Anti-MRSA agent 40 Related Antibodies

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Description

Anti-MRSA agent 40 (Compound 7-8) is a potent agent against Methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 40 exhibits significant antibacterial activity against MRSA2 and S. aureus ATCC 29213, with its MIC values being 1 μg/mL. Anti-MRSA agent 40 causes depolarization of the cell membrane, damages membrane integrity, and simultaneously increases the level of ROS within MRSA2, ultimately leading to cell lysis and death. Anti-MRSA agent 40 exhibits extremely low cytotoxicity, and there is almost no risk of hemolysis at the effective antibacterial concentration. Anti-MRSA agent 40 shows significant efficacy in the MRSA2 skin abscess model. Anti-MRSA agent 40 can be used for research on anti-MRSA infections[1].

Molecular Weight

640.68

Formula

C36H36N2O9
SMILES

O=C(O)C1=CC=C(/C=N\NC(CCCOC2=CC(OC(C=C(OC(C)(C)C=C3)C3=C4O)=C4C5=O)=C5C(C/C=C(C)/C)=C2OC)=O)C=C1
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Anti-MRSA agent 40 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-MRSA agent 40BacterialReactive Oxygen Species (ROS)α-MangostinacylhydrazoneMRSAantibacterialsynergistic effectInhibitorinhibitorinhibit

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