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Results for "

YES1

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Recombinant Proteins

1

Isotope-Labeled Compounds

6

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135299
    CH6953755
    3 Publications Verification

    		 Src Cancer
    CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC50 of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo [1].
    CH6953755
  • HY-112096
    eCF506
    4 Publications Verification

    NXP900

    		 Src Cancer
    eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer [1].
    eCF506
  • HY-136848
    SM1-71

    		MAP3K Src FGFR Ribosomal S6 Kinase (RSK) LIM Kinase (LIMK) Cancer
    SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines [1] .
    SM1-71
  • HY-RS16970
    Yes1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Yes1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Yes1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Yes1 Mouse Pre-designed siRNA Set A
    Yes1 Mouse Pre-designed siRNA Set A
  • HY-RS15922
    YES1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    YES1 Human Pre-designed siRNA Set A contains three designed siRNAs for YES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    YES1 Human Pre-designed siRNA Set A
    YES1 Human Pre-designed siRNA Set A
  • HY-RS23413
    Yes1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Yes1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Yes1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Yes1 Rat Pre-designed siRNA Set A
    Yes1 Rat Pre-designed siRNA Set A
  • HY-E70293
    N-Acetylgalactosaminyltransferase 12

    GALNT12

    		 Endogenous Metabolite YAP Cancer
    N-Acetylgalactosaminyltransferase 12 (GALNT12) belongs to the uridine diphosphate N-acetylgalactosamine gene family and is involved in the biological processes of many diseases, such as tumor progression. N-Acetylgalactosaminyltransferase 12 is a potential biomarker for fibrosarcoma, and its high expression level is closely related to the yes1-associated transcriptional regulator (YAP1) signaling pathway [1].
    N-Acetylgalactosaminyltransferase 12
  • HY-145373
    BMS-986143

    		Btk Inflammation/Immunology
    BMS-986143 is an orally active, reversible BTK inhibitor with an IC50 of 0.26 nM. BMS-986143 also inhibits TEC, BLK, BMX, TXK FGR, YES1, ITK with IC50s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM,19 nM, 21 nM, respectively. BMS-986143 can be used for the research of autoimmune diseases [1].
    BMS-986143
  • HY-112096S
    eCF506-d5

    NXP900-d5

    		 Src Isotope-Labeled Compounds Cancer
    eCF506-d5 (NXP900-d5) is deuterated labeled eCF506 (HY-112096). eCF506 is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer [1] .
    eCF506-d5

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