Search Result
        
        
            
                Results for "
Vitamin B3
" in MedChemExpress (MCE) Product Catalog:
            
         
        
        
            
                
            
            
            
            
            
            
            
            
                
            
            
            
                
                    18
Isotope-Labeled Compounds
 
            
            
            
            
                
            
         
        
            
            
                
                    
                    
                        
                            | Cat. No. | Product Name | Target | Research Areas | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-B0143
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                                                | Nicotinic acid;  Vitamin B3 | Autophagy
                                                    
                                                        Endogenous Metabolite | Cardiovascular Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases  . |  
 
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                                    - HY-B0143R
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                                                | Nicotinic acid (standard); Vitamin B3 (standard) | Reference Standards
                                                    
                                                        Autophagy
                                                    
                                                        Endogenous Metabolite | Cardiovascular Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases  . |  
 
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                                    - HY-B0143S2
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                                    - HY-B0143S3
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                                    - HY-123033A
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                                                |  | Sirtuin
                                                    
                                                        Endogenous Metabolite | Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide riboside Chloride, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease . |  
 
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                                    - HY-N0623R
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                                                | Tryptophan (standard); Tryptophane (standard) | Others
                                                    
                                                        Reference Standards | Metabolic Disease |  
                                                | L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels   . |  
 
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                                    - HY-B0143A
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                                                | Nicotinic acid hydrochloride; Vitamin B3 hydrochloride | Endogenous Metabolite
                                                    
                                                        Apoptosis | Cardiovascular Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases  . |  
 
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                                    - HY-16742BR
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                                                |  | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Topoisomerase | Infection |  
                                                | Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases  . |  
 
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                                    - HY-B0143S4
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                                                |  | Autophagy
                                                    
                                                        Endogenous Metabolite | Cancer |  
                                                | Niacin- 15N, 13C3 is the  13C and  15N labeled Niacin . Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases  . |  
 
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                                    - HY-123033
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                                                |  | Sirtuin
                                                    
                                                        Endogenous Metabolite | Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide riboside, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease . |  
 
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                                    - HY-123033B
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                                                |  | Sirtuin
                                                    
                                                        Endogenous Metabolite | Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide riboside tartrate, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside tartrate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside tartrate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease . |  
 
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                                    - HY-123033C
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                                                |  | Sirtuin
                                                    
                                                        Endogenous Metabolite | Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide riboside malate, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside malate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside malate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease . |  
 
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                                    - HY-123033D
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                                                |  | Endogenous Metabolite
                                                    
                                                        Sirtuin | Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide riboside (triflate), an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside (triflate) is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside (triflate) reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease . |  
 
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                                    - HY-123033AR
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                                                |  | Reference Standards
                                                    
                                                        Sirtuin
                                                    
                                                        Endogenous Metabolite | Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide riboside (chloride) (Standard) is the analytical standard of Nicotinamide riboside (chloride). This product is intended for research and analytical applications. Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2]. |  
 
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                                    - HY-N0623S5
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                                                | Tryptophan-d8; Tryptophane-d8 | Endogenous Metabolite | Metabolic Disease |  
                                                | L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S9
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                                                | Tryptophan-d3; Tryptophane-d3 | Endogenous Metabolite | Metabolic Disease |  
                                                | L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S
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                                                | Tryptophan-d5; Tryptophane-d5 | Endogenous Metabolite | Metabolic Disease |  
                                                | L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-B0893
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                                                | Nicotinyl alcohol;  Pyridine-3-carbinol | CETP | Metabolic Disease |  
                                                | 3-Pyridinemethanol (Nicotinyl alcohol), a pyridine derivative, is a cholesterol-lowering agent. 3-Pyridinemethanol can be selectively oxidized to vitamin B3   . |  
 
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                                    - HY-N0623S1
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                                                | Tryptophan-13C; Tryptophane-13C | Endogenous Metabolite | Metabolic Disease |  
                                                | L-Tryptophan- 13C is the  13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S7
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                                    - HY-N0623S2
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                                    - HY-N0623S8
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                                                | Tryptophan-15N2; Tryptophane-15N2 | Endogenous Metabolite | Metabolic Disease |  
                                                | L-Tryptophan- 15N2 is the  15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0153A
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                                                | Naringoside hydrate | Cytochrome P450
                                                    
                                                        Apoptosis
                                                    
                                                        Mitophagy | Cancer |  
                                                | Niacinamide ascorbate is a vitamin complex that combines niacinamide (vitamin B3) and ascorbic acid (vitamin C). Niacinamide ascorbate reduces the risk of radiation-induced acute leukemia, breast cancer, thyroid cancer, and other somatic and genetic mutations following exposure to ionizing radiation doses . |  
 
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                                    - HY-N0623S3
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                                    - HY-N0623S10
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                                                |  | Endogenous Metabolite | Metabolic Disease
                                                    
                                                        Cancer |  
                                                | L-Phenylalanine,Indole- 15N is the  15N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2]. |  
 
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                                    - HY-N0623S4
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                                                | Tryptophan-13C11,15N2; Tryptophane-13C11,15N2 | Endogenous Metabolite | Metabolic Disease |  
                                                | L-Tryptophan- 13C11, 15N2 is the  13C- and  15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S6
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                                    - HY-B0150S
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                                                | Niacinamide-d4; Nicotinic acid amide-d4 | Sirtuin
                                                    
                                                        Endogenous Metabolite | Neurological Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of  SIRT1. |  
 
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                                    - HY-B0893R
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                                                |  | CETP
                                                    
                                                        Reference Standards | Metabolic Disease |  
                                                | 3-Pyridinemethanol (Standard) is the analytical standard of 3-Pyridinemethanol. This product is intended for research and analytical applications. 3-Pyridinemethanol (Nicotinyl alcohol), a pyridine derivative, is a cholesterol-lowering agent. 3-Pyridinemethanol can be selectively oxidized to vitamin B3   . |  
 
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                                    - HY-B0150S2
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                                                | Niacinamide-13C6; Nicotinic acid amide-13C6 | Endogenous Metabolite
                                                    
                                                        Sirtuin | Neurological Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide- 13C6 is the  13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of  SIRT1. |  
 
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                                    - HY-W015793
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                                                |  | GABA Receptor | Others |  
                                                | 6-Aminonicotinic acid is a GABAA receptor agonist with Ki value of 4.4 nM. 6-Aminonicotinic acid can be formed via electrocatalytic synthesis at silver cathodes. 6-Aminonicotinic acid has a variety of biological properties, such as protein synthesis inhibitor, vitamin B3 agonist, and modulating agent in chemotherapy  . |  
 
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                                    - HY-B0150A
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                                                | Niacinamide Hydrochloride; Nicotinic acid amide Hydrochloride | Sirtuin
                                                    
                                                        Endogenous Metabolite
                                                    
                                                        HBV | Infection
                                                    
                                                        Cancer |  
                                                | Nicotinamide Hydrochloride is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide Hydrochloride also inhibits SIRT1. Nicotinamide Hydrochloride increases cellular NAD+, ATP, ROS levels. Nicotinamide Hydrochloride inhibits tumor growth and improves survival. Nicotinamide Hydrochloride also has anti-HBV activity    . |  
 
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                                    - HY-B0150
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                                                | 
                                                        
                                                            Nicotinamide
                                                            
                                                        
                                                        
                                                            
                                                                
                                                                    Maximum Cited Publications 80 Publications Verification Niacinamide;  Nicotinic acid amide | Organoid
                                                    
                                                        Endogenous Metabolite
                                                    
                                                        Sirtuin
                                                    
                                                        HBV | Cancer |  
                                                | Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity    . |  
 
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                                    - HY-B0150S1
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                                                | Niacinamide-15N,13C3; Nicotinic acid amide-15N,13C3 | Endogenous Metabolite
                                                    
                                                        Sirtuin | Neurological Disease
                                                    
                                                        Cancer |  
                                                | Nicotinamide- 15N, 13C3 is the  13C-labeled and  15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of  SIRT1. |  
 
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                                    - HY-B0150S3
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                                                | Niacinamide-d3;  Nicotinic acid amide-d3 | Isotope-Labeled Compounds
                                                    
                                                        Endogenous Metabolite
                                                    
                                                        Organoid
                                                    
                                                        Sirtuin
                                                    
                                                        HBV | Cancer |  
                                                | Nicotinamide-d3 (Niacinamide-d3) is deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity    . |  
 
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                                    - HY-B0150R
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                                                | Niacinamide(Standard); Nicotinic acid amide (Standard) | Reference Standards
                                                    
                                                        Endogenous Metabolite
                                                    
                                                        Sirtuin | Cancer |  
                                                | Nicotinamide (Standard) is the analytical standard of Nicotinamide. This product is intended for research and analytical applications. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity    . |  
 
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                            | Cat. No. | Product Name | Category | Target | Chemical Structure | 
                    
                    
                 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-B0143S2
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                                                | 
                                                        
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    1 Publications Verification |  
                                                | Niacin-d4 is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group. |  
 
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                                    - HY-B0143S3
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                                                |  |  
                                                | Niacin- 13C6 is the  13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group. |  
 
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                                    - HY-N0623S5
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                                                |  |  
                                                | L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S9
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                                                |  |  
                                                | L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S
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                                                |  |  
                                                | L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S1
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                                                |  |  
                                                | L-Tryptophan- 13C is the  13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S7
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                                                |  |  
                                                | L-Tryptophan- 15N is the  15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. |  
 
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                                    - HY-N0623S2
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                                                | 
                                                        
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    1 Publications Verification |  
                                                | L-Tryptophan- 13C11 is the  13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S8
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                                                |  |  
                                                | L-Tryptophan- 15N2 is the  15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-B0143S4
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                                                |  |  
                                                | Niacin- 15N, 13C3 is the  13C and  15N labeled Niacin . Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases  . |  
 
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                                    - HY-N0623S3
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                                                |  |  
                                                | L-Tryptophan-1- 13C is the  13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S10
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                                                |  |  
                                                | L-Phenylalanine,Indole- 15N is the  15N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2]. |  
 
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                                    - HY-N0623S4
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                                                |  |  
                                                | L-Tryptophan- 13C11, 15N2 is the  13C- and  15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-N0623S6
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                                                |  |  
                                                | L-Tryptophan- 15N2,d8 is the deuterium and  15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 . |  
 
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                                    - HY-B0150S
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                                                | 
                                                        
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    1 Publications Verification |  
                                                | Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of  SIRT1. |  
 
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                                    - HY-B0150S2
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                                                |  |  
                                                | Nicotinamide- 13C6 is the  13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of  SIRT1. |  
 
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                                    - HY-B0150S1
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                                                |  |  
                                                | Nicotinamide- 15N, 13C3 is the  13C-labeled and  15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of  SIRT1. |  
 
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                                    - HY-B0150S3
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                                                |  |  
                                                | Nicotinamide-d3 (Niacinamide-d3) is deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity    . |  
 
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                                | Cat. No. | Product Name |  | Classification | 
                        
                        
                            
                            
                        - 
                            
                                - HY-N0623
- 
                                    
                                        
                                            | Tryptophan;  Tryptophane |  | Freeze-drying Protective Agents
                                                    
                                                    
                                                
                                                    
                                                    
                                                        Solubilizing Agents |  
                                            | L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels   . |  
 
 
 
                
         
        
        
        
        
        
        
            
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