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Results for "

TSC2

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134904
    RMC-6272
    2 Publications Verification

    RM-006

    		 mTOR Cancer
    RMC-6272 (RM-006) is a bi-steric mTORC1-selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors .
    RMC-6272
  • HY-150229
    306-N16B

    		Liposome Cancer
    306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies [2].
    306-N16B
  • HY-RS23540
    Tsc2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Tsc2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tsc2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tsc2 Rat Pre-designed siRNA Set A
    Tsc2 Rat Pre-designed siRNA Set A
  • HY-RS17096
    Tsc2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Tsc2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tsc2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tsc2 Mouse Pre-designed siRNA Set A
    Tsc2 Mouse Pre-designed siRNA Set A
  • HY-RS15132
    TSC2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TSC2 Human Pre-designed siRNA Set A contains three designed siRNAs for TSC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TSC2 Human Pre-designed siRNA Set A
    TSC2 Human Pre-designed siRNA Set A
  • HY-155475
    mTORC1-IN-2

    		mTOR Cardiovascular Disease
    mTORC1-IN-2 (compound H3) is a NO donor compound that alleviates vasodilation and attenuates myocardial hypoxic injury. mTORC1-IN-2 upregulates TSC2-P expression and inhibits mTORC1 expression .
    mTORC1-IN-2
  • HY-134922
    NS1-IN-1

    		Influenza Virus Infection
    NS1-IN-1 (compound 3) is a potent NS1 inhibitor. NS1 is a major influenza A virus virulence factor that inhibits host gene expression. NS1-IN-1 decreases viral protein levels, contributing to the reduction of virus replication. NS1-IN-1 shows antiviral activity by repressing the activity of mTORC1 in a TSC1-TSC2-dependent manner .
    NS1-IN-1

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