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T 4

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8

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18341
    L-Thyroxine
    Maximum Cited Publications
    8 Publications Verification

    Levothyroxine; T4

    		 Thyroid Hormone Receptor Endogenous Metabolite Endocrinology Cancer
    L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine
  • HY-E70094
    T4 UvsX Recombinase

    		DNA/RNA Synthesis Others
    T4 UvsX Recombinase helps initiate DNA replication on a double-stranded DNA template by catalyzing synapsis between the template and a homologous DNA single strand that serves as primer. T4 UvsX Recombinase greatly amplifies the snap-back (hairpin-primed) DNA synthesis that is catalyzed by the T4 DNA polymerase holoenzyme on linear, single-stranded DNA templates .
    T4 UvsX Recombinase
  • HY-E70095
    T4 UvsY Protein

    		Others Others
    T4 UvsY Protein is an accessory protein for in vitro catalysis of strand exchange. T4 UvsY Protein enhances strand exchange by UvsX protein by interacting specifically with UvsX protein. UvsY protein enhances the rate of single-stranded-DNA-dependent ATP hydrolysis by UvsX protein .
    T4 UvsY Protein
  • HY-18341B
    L-Thyroxine sodium
    Maximum Cited Publications
    8 Publications Verification

    Levothyroxine sodium; T4 sodium

    		 Thyroid Hormone Receptor Endogenous Metabolite Endocrinology Cancer
    L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine sodium
  • HY-18341R
    L-Thyroxine (Standard)

    Levothyroxine (Standard); T4 (Standard)

    		 Reference Standards Thyroid Hormone Receptor Endogenous Metabolite Endocrinology Cancer
    L-Thyroxine (Standard) is the analytical standard of L-Thyroxine. This product is intended for research and analytical applications. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine (Standard)
  • HY-161564
    T4/OVA

    		Biochemical Assay Reagents Inflammation/Immunology
    T4/OVA is a conjugate of T4 peptide (thyroxine T4) and ovalbumin. T4/OVA is a altered peptide, which can be used to stimulate OT-I CD8+ T cells .
    T4/OVA
  • HY-E70585
    T4 Phage β-glucosyltransferase

    		DNA/RNA Synthesis Others
    T4 Phage β-glucosyltransferase is a DNA-modifying enzyme encoded by bacteriophage T4. T4 Phage β-glucosyltransferase transfers glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4 DNA .
    T4 Phage β-glucosyltransferase
  • HY-E70578
    T4 Endonuclease V

    		DNA Glycosylase Others
    T4 Endonuclease V is a dual-activity DNA glycosylase that combines the activities of DNA N-glycosylase and AP lyase. T4 Endonuclease V can repair ultraviolet (UV)-induced cyclobutane pyrimidine dimers in DNA .
    T4 Endonuclease V
  • HY-E70091
    T4 RNA ligase

    		DNA/RNA Synthesis Others
    T4 RNA ligase is an ATP-dependent RNA ligase that can catalyze the formation of phosphodiester bonds between the 5'-P end and the 3'-OH end of single-stranded RNA, single-stranded DNA or single nucleotides between molecules or within molecules. T4 RNA ligase is used for enzymatic low ribonucleotide synthesis and 3′ end labeling of RNA. It is mainly used for RNA and RNA, but can also be used for RNA and single nucleotides .
    T4 RNA ligase
  • HY-18341BR
    L-Thyroxine sodium (Standard)

    Levothyroxine sodium (Standard); T4 sodium (Standard)

    		 Reference Standards Thyroid Hormone Receptor Endogenous Metabolite Endocrinology Cancer
    L-Thyroxine (sodium) (Standard) is the analytical standard of L-Thyroxine (sodium). This product is intended for research and analytical applications. L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine sodium (Standard)
  • HY-114272A
    T4-ATA (S-isomer)

    		Thyroid Hormone Receptor Endocrinology
    T4-ATA S-isomer is the S-isomer of T4-ATA, which is the active form of the thyroid hormone.
    T4-ATA (S-isomer)
  • HY-158269
    T4-BSA

    		Thyroid Hormone Receptor Endogenous Metabolite Inflammation/Immunology
    T4-BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    T4-BSA
  • HY-18341S1
    Thyroxine hydrochloride-13C6

    Levothyroxine-13C6; T4-13C6

    		 Isotope-Labeled Compounds Thyroid Hormone Receptor Endogenous Metabolite Endocrinology
    Thyroxine hydrochloride- 13C6 is the 13C-labeled L-Thyroxine. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    Thyroxine hydrochloride-13C6
  • HY-18341S4
    L-Thyroxine-13C6-1

    Levothyroxine-13C6-1; T4-13C6-1

    		 Isotope-Labeled Compounds Endogenous Metabolite Thyroid Hormone Receptor Endocrinology
    L-Thyroxine- 13C6-1 (Levothyroxine- 13C6-1; T4- 13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine-13C6-1
  • HY-W582400
    (T-4)-Copper(1+), bis[2,9-bis(4-methoxyphenyl)-1,10-phenanthroline-κN1,κN10]-, chloride

    		Biochemical Assay Reagents
    (T-4) -copper (1+), bis[2,9-bis(4-methoxyphenyl)-1, 10-phenanthroline-κn1,κN10]-, chloride is a chloride reagent .
    (T-4)-Copper(1+), bis[2,9-bis(4-methoxyphenyl)-1,10-phenanthroline-κN1,κN10]-, chloride
  • HY-P3005
    T4 DNA ligase

    		Biochemical Assay Reagents Others
    DNA ligase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    T4 DNA ligase
  • HY-101406R
    Thyroxine sulfate (Standard)

    T4 Sulfate (Standard)

    		 Reference Standards Thyroid Hormone Receptor Drug Metabolite Endogenous Metabolite Metabolic Disease Endocrinology
    Thyroxine sulfate (Standard) is the analytical standard of Thyroxine sulfate. This product is intended for research and analytical applications. Thyroxine sulfate is a thyroid hormone metabolite.
    Thyroxine sulfate (Standard)
  • HY-112514
    1,3,6,8-Tetrahydroxynaphthalene
    1 Publications Verification

    1,3,6,8-THN; T4HN

    		 Others Others
    1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin .
    1,3,6,8-Tetrahydroxynaphthalene
  • HY-101406
    Thyroxine sulfate
    1 Publications Verification

    T4 Sulfate

    		 Thyroid Hormone Receptor Drug Metabolite Endogenous Metabolite Metabolic Disease Endocrinology
    Thyroxine sulfate is a thyroid hormone metabolite.
    Thyroxine sulfate
  • HY-Y1239S
    Trihydro(tetrahydrofuran)boron-d3

    (T-4)-Trihydro-d3-(tetrahydrofuran)boron; Hydride-d, boron complex; Trideuterio(tetrahydrofuran)boron; Trideuteroborane-tetrahydrofuran complex

    		 Isotope-Labeled Compounds Others
    Trihydro(tetrahydrofuran)boron-d3 is the deuterium labeled Trihydro(tetrahydrofuran)boron .
    Trihydro(tetrahydrofuran)boron-d3
  • HY-P5411
    OVA-T4 Peptide

    SIITFEKL, OVA (257-264) Variant

    		 MHC Others
    OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a biological active peptide. (T4 peptide (SIITFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)
    OVA-T4 Peptide
  • HY-A0152
    D-Thyroxine

    D-T4

    		 Endogenous Metabolite Metabolic Disease
    D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia .
    D-Thyroxine
  • HY-A0152A
    D-Thyroxine sodium

    D-T4 sodium

    		 Thyroid Hormone Receptor Cardiovascular Disease
    D-thyroxine (D-T4) sodium is an orally active thyroid hormone that inhibits the secretion of TSH. D-thyroxine sodium can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-thyroxine sodium can be used for the study of hypercholesterolemia .
    D-Thyroxine sodium
  • HY-A0152R
    D-Thyroxine (Standard)

    D-T4 (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    D-Thyroxine (Standard) is the analytical standard of D-Thyroxine (HY-A0152). This product is intended for research and analytical applications. D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia .
    D-Thyroxine (Standard)
  • HY-120858
    25T4-NBOMe hydrochloride

    		Drug Derivative Neurological Disease
    25T4-NBOMe hydrochloride is a derivative of 2C-T-4, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine .
    25T4-NBOMe hydrochloride
  • HY-P991410
    5T4_0108

    MEDI0641 antibody

    		 Wnt Cancer
    5T4_0108 (MEDI0641 antibody) is a human monoclonal antibody (mAb) targeting TPBG. 5T4_0108 can be used in breast and prostate cancer research .
    5T4_0108
  • HY-W010669
    L-Thyroxine sodium xhydrate
    5+ Cited Publications

    Sodium levothyroxine

    		 Thyroid Hormone Receptor Endocrinology
    L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
    L-Thyroxine sodium xhydrate
  • HY-18341A
    L-Thyroxine sodium salt pentahydrate
    Maximum Cited Publications
    8 Publications Verification

    Sodium levothyroxine pentahydrate

    		 Thyroid Hormone Receptor Endogenous Metabolite Endocrinology Cancer
    L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine sodium salt pentahydrate
  • HY-18341S2
    L-Thyroxine-13C6

    		Thyroid Hormone Receptor Endogenous Metabolite Endocrinology
    L-Thyroxine- 13C6 is the 13C labeled L-Thyroxine . L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine-13C6
  • HY-W010669R
    L-Thyroxine sodium xhydrate (Standard)

    Sodium levothyroxine (Standard)

    		 Reference Standards Thyroid Hormone Receptor Endocrinology
    L-Thyroxine sodium xhydrate (Standard) is the analytical standard of L-Thyroxine sodium xhydrate. This product is intended for research and analytical applications. L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
    L-Thyroxine sodium xhydrate (Standard)
  • HY-18341AR
    L-Thyroxine sodium salt pentahydrate (Standard)

    		Thyroid Hormone Receptor Endogenous Metabolite Endocrinology Cancer
    L-Thyroxine (sodium salt pentahydrate) (Standard) is the analytical standard of L-Thyroxine (sodium salt pentahydrate). This product is intended for research and analytical applications. L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
    L-Thyroxine sodium salt pentahydrate (Standard)
  • HY-W008859
    Tetrac
    1 Publications Verification

    Tetraiodothyroacetic acid; 3,3',5,5'-Tetraiodothyroacetic acid

    		 Integrin Endogenous Metabolite Cancer
    Tetrac (Tetraiodothyroacetic acid), a derivative of L-thyroxine (T4), is a thyrointegrin receptor antagonist. Tetrac blocks the actions of T4 and 3,5,3'-triiodo-L-thyronine (T3) at the cell surface receptor for thyroid hormone on integrin αvβ3. Tetra has anti-angiogenic and anti-tumor activities .
    Tetrac
  • HY-RS16482
    OR2T4 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    OR2T4 Human Pre-designed siRNA Set A contains three designed siRNAs for OR2T4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    OR2T4 Human Pre-designed siRNA Set A
    OR2T4 Human Pre-designed siRNA Set A
  • HY-115451
    Photoregulin 3

    		DNA/RNA Synthesis Others
    Photoregulin 3 (compound T4) can promote distal-to-proximal alternative polyadenylation (APA) activity in multiple transcripts .
    Photoregulin 3
  • HY-14998
    Halofenate

    MK 185

    		 β-catenin PPAR Wnt Endocrinology
    Halofenate, structurally akin to clofibrate, was evaluated in hypertriglyceridemic patients over 6-week periods in a controlled, double-blind crossover trial. It effectively reduced serum triglycerides by 50%, with minimal impact on serum cholesterol levels. Additionally, it lowered serum uric acid by 30% and exhibited uricosuric effects independent of glomerular filtration rate. Halofenate was associated with a significant increase in plasma thyroxine (T4), accompanied by a decrease in protein-bound iodine and T4 by column. In vitro studies confirmed its ability to displace T4 from thyroid-binding proteins, suggesting a thyroxine-displacing effect, which could influence thyroid function in vivo .
    Halofenate
  • HY-P9998
    Semzuvolimab

    UB421

    		 HIV Cancer
    Semzuvolimab is a human IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4). Human CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection .
    Semzuvolimab
  • HY-18341F1
    Biotin-hexanamide-(L-Thyroxine)

    		Thyroid Hormone Receptor Others
    Biotin-hexanamide-(L-Thyroxine) is biotinylated L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism .
    Biotin-hexanamide-(L-Thyroxine)
  • HY-112624J
    Dextran T4 (MW 4,000)

    Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)

    		 Bacterial Others
    Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
    Dextran T4 (MW 4,000)
  • HY-114918
    MS438

    		TSH Receptor Endocrinology
    MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice .
    MS438
  • HY-18341F
    Biotin-(L-Thyroxine)

    		Thyroid Hormone Receptor Endogenous Metabolite Endocrinology
    Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .
    Biotin-(L-Thyroxine)
  • HY-126927
    TTR stabilizer L6

    		Transthyretin (TTR) Neurological Disease
    TTR stabilizer L6 (L6) binds to the T4 binding pocket of transthyretin (TTR), which can prevent the dissociation of TTR to monomer. TTR stabilizer L6 is promising for research of familial amyloid polyneuropathy .
    TTR stabilizer L6
  • HY-107903
    Thyroglobulin

    Thyroglobulin from bovine

    		 Biochemical Assay Reagents Cancer
    Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle .
    Thyroglobulin
  • HY-N1957
    Gamma-Mangostin
    2 Publications Verification

    γ-Mangostin

    		 5-HT Receptor COX Transthyretin (TTR) Metabolic Disease Inflammation/Immunology Cancer
    Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
    Gamma-Mangostin
  • HY-B1234
    Octinoxate

    Octyl methoxycinnamate

    		 Androgen Receptor Estrogen Receptor/ERR Thyroid Hormone Receptor Cytochrome P450 Metabolic Disease Endocrinology
    Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
    Octinoxate
  • HY-B1234S
    Octinoxate-13C,d3

    		Cytochrome P450 Thyroid Hormone Receptor Androgen Receptor Estrogen Receptor/ERR Isotope-Labeled Compounds Metabolic Disease Endocrinology
    Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
    Octinoxate-13C,d3
  • HY-N1957R
    Gamma-Mangostin (Standard)

    γ-Mangostin (Standard)

    		 Reference Standards 5-HT Receptor COX Transthyretin (TTR) Metabolic Disease Inflammation/Immunology Cancer
    Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
    Gamma-Mangostin (Standard)
  • HY-W713284
    2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate

    		Isotope-Labeled Compounds Cytochrome P450 Estrogen Receptor/ERR Androgen Receptor Thyroid Hormone Receptor Endocrinology
    2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate is the deuterium labeled Octinoxate (HY-B1234). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
    2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate
  • HY-162045
    Ru-4T

    		Biochemical Assay Reagents Cancer
    Ru-4T is a phototherapy agent. Ru-4T has phototherapeutic efficacy (PI = 114,000) against melanoma cells (SK-MEL-28) under broad-band visible light (400-700 nm) with EC50 values of 740 pM .
    Ru-4T
  • HY-79256
    MMAF-OMe
    1 Publications Verification

    Monomethyl auristatin F methyl ester

    		 ADC Payload Cancer
    MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4 -) cell lines, respectively.
    MMAF-OMe
  • HY-P991095
    ALG.APV-527

    APV-527; ATOR-1016

    		 Transmembrane Glycoprotein Cancer
    ALG.APV-527 (APV-527) is a bispecific 4-1BB (CD137) and 5T4 antibody. ALG.APV-527 is designed to activate 4-1BB on T and natural killer (NK) cells only when simultaneously bound to 5T4-expressing tumor cells. ALG.APV-527 has a potent antitumor activity .
    ALG.APV-527

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