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Solid-phase synthesis

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

1

Fluorescent Dye

3

Biochemical Assay Reagents

4

Peptides

5

Isotope-Labeled Compounds

1

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y1636
    Fmoc-Arg(Pbf)-OH

    		Amino Acid Derivatives Biochemical Assay Reagents Metabolic Disease
    Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
    Fmoc-Arg(Pbf)-OH
  • HY-W010756
    FMOC-AM

    		Biochemical Assay Reagents Others
    FMOC-AM is a derivative of aminomethyl resin. FMOC-AM provides a solid-phase carrier basis for peptide chain synthesis and can be used in solid-phase peptide synthesis .
    FMOC-AM
  • HY-W140465
    L-Homotyrosine

    		Drug Derivative Others
    L-Homotyrosine is a tyrosine derivative that can be used for solid-phase peptide synthesis .
    L-Homotyrosine
  • HY-W013081
    Fmoc-Gln(Trt)-OH

    		Amino Acid Derivatives Others
    Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc. Fmoc-Gln(Trt)-OH can be used in solid-phase peptide synthesis .
    Fmoc-Gln(Trt)-OH
  • HY-W002327
    Fmoc-Asn(Trt)-OH

    		Biochemical Assay Reagents Others
    Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .
    Fmoc-Asn(Trt)-OH
  • HY-131094
    H-Gly-D-Tyr-OH

    		Others Others
    H-Gly-D-Tyr-OH is used for the the solid-phase peptide synthesis.
    H-Gly-D-Tyr-OH
  • HY-131091
    Boc-Glu(OBzl)-OSu

    		Amino Acid Derivatives Others
    Boc-Glu(OBzl)-OSu can be used for the solid-phase peptide synthesis containing glutamate benzyl ester residues.
    Boc-Glu(OBzl)-OSu
  • HY-W1119950
    3'-NH-Tr-2',3'-DMF-ddA- 5'-CE-Phosphoramidite

    		Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Others
    3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is an adenine nucleotide monomer precursor used in solid-phase synthesis of oligonucleotides, particularly modified oligonucleotides, such as those with DNA chain end modifications. 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite, with trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, is a ddNTP adenosine nucleoside useful in applications such as solid-phase oligonucleotide synthesis, probe design, and chain-termination sequencing .
    3'-NH-Tr-2',3'-DMF-ddA- 5'-CE-Phosphoramidite
  • HY-151825
    Fmoc-L-Phe(4-NH-Poc)-OH

    		ADC Linker Others
    Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .
    Fmoc-L-Phe(4-NH-Poc)-OH
  • HY-W142064
    Fmoc-L-photo-proline

    		Antibiotic Others
    Fmoc-L-photo-proline is a photo-crosslinking amino acid which can be incorporated into synthetic peptides using solid-phase Fmoc chemistry. Fmoc-L-photo-proline can synthesis of cyclic peptidomimetic antibiotic and be used for preparation of diverse peptide-based photoaffinity probes research .
    Fmoc-L-photo-proline
  • HY-78574
    N-Benzoylcytidine

    		Nucleoside Antimetabolite/Analog Others
    N-Benzoylcytidine is a substrate for uracil-cytidine kinase 1 (UCK1) and UCK2. N-Benzoylcytidine can be used to synthesize 2-OH protective groups for solid-phase RNA synthesis，as well as synthetic oligonucleotides for UV induction and targeted gene silencing in zebrafish embryos .
    N-Benzoylcytidine
  • HY-Y1636S1
    Fmoc-Arg(Pbf)-OH-13C6

    		Isotope-Labeled Compounds Others
    Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH . Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
    Fmoc-Arg(Pbf)-OH-13C6
  • HY-171341
    H-Pro-2-ClTrt resin

    		Biochemical Assay Reagents Others
    H-Pro-2-ClTrt resin is an acid-sensitive resin for solid-phase peptide synthesis. H-Pro-2-ClTrt resin binds to amino acids through an acid-labile chlorotrityl linker. H-Pro-2-ClTrt resin is promising for research of peptide drug development .
    H-Pro-2-ClTrt resin
  • HY-W013081S
    Fmoc-Gln(Trt)-OH-13C5,15N2

    		Isotope-Labeled Compounds Amino Acid Derivatives Others
    Fmoc-Gln(Trt)-OH- 13C5, 15N2 is the 13C-labeled and 15N-labeled Fmoc-Gln(Trt)-OH (HY-W013081). Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc. Fmoc-Gln(Trt)-OH can be used in solid-phase peptide synthesis .
    Fmoc-Gln(Trt)-OH-13C5,15N2
  • HY-W002327S
    Fmoc-Asn(Trt)-OH-13C4,15N2

    		Isotope-Labeled Compounds Others
    Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled Fmoc-Asn(Trt)-OH (HY-W002327). Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .
    Fmoc-Asn(Trt)-OH-13C4,15N2
  • HY-Y1636S
    Fmoc-Arg(Pbf)-OH-13C6,15N4

    		Isotope-Labeled Compounds Amino Acid Derivatives Biochemical Assay Reagents Metabolic Disease
    Fmoc-Arg(Pbf)-OH- 13C6, 15N4 is the 13C-labeled and 15N-labeled Fmoc-Arg(Pbf)-OH (HY-Y1636). Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
    Fmoc-Arg(Pbf)-OH-13C6,15N4
  • HY-W1119956
    5’-(E)-VPG Phosphoramidite

    5'(E)-VP-2'-OMe-iBu-G Phosphoramidite

    		 Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Infection
    5'-(E)-VPG Phosphoramidite (5'(E)-VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research .
    5’-(E)-VPG Phosphoramidite
  • HY-W016413
    4-(Hydroxymethyl)phenoxyacetic acid

    		Biochemical Assay Reagents Others
    4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis .
    4-(Hydroxymethyl)phenoxyacetic acid
  • HY-Y0912
    HBTU

    N-HBTU

    		 Biochemical Assay Reagents Others
    HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis .
    HBTU
  • HY-112516
    Fmoc-Lys(amino aldehyde)-Boc

    		Amino Acid Derivatives Others
    Fmoc-Lys(amino aldehyde)-Boc is a lysine derivative, and is very sensitive to acid and heat. Fmoc-Lys(amino aldehyde)-Boc and can be used in solid phase synthesis .
    Fmoc-Lys(amino aldehyde)-Boc
  • HY-134517
    Fmoc-HoCys(ACM)-OH

    		Amino Acid Derivatives Others
    Fmoc-HoCys(ACM)-OH, a homolog of cysteine, is synthesized from L-methionine. Fmoc-HoCys(ACM)-OH also can be used for the synthesis of solid phase peptide .
    Fmoc-HoCys(ACM)-OH
  • HY-164623
    CUTAG CPG (pore size 1000 Å, 25-35 μmol/g)

    		Biochemical Assay Reagents Others
    CUTAG CPG (pore size 1000 Å, 25-35 μmol/g) is a CUTAG-conjugated controlled pore glass (CPG), that can be used for solid phase oligonucleotides synthesis .
    CUTAG CPG (pore size 1000 Å, 25-35 μmol/g)
  • HY-P2439
    MEN 10208

    		Neurokinin Receptor Others
    MEN 10208 is a neurokinin A antagonist prepared by solid phase synthesis. The Fmoc strategy has more advantages than the Boc strategy in its preparation, and can obtain products with higher yield and purity.
    MEN 10208
  • HY-Y0973
    BOP hexafluorophosphate

    		Biochemical Assay Reagents Others
    BOP (hexafluorophosphate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. BOP hexafluorophosphate can be used in stepwise solid phase synthesis to prepare fragments of [Ala 15]-GRF(1-29)-NH2 .
    BOP hexafluorophosphate
  • HY-W010712
    Fmoc-His(Trt)-OH

    		Amino Acid Derivatives Others
    Fmoc-His (Trt)-OH is a histidine derivative. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
    Fmoc-His(Trt)-OH
  • HY-118161
    1-Adamantylaspartate

    beta-1-Adamantylaspartic acid

    		 Biochemical Assay Reagents Others
    1-Adamantylaspartate is a newly developed β-β-1-imidopropionic acid used to synthesize the C-terminal octapeptide of the β subunit of human chorionic gonadotropin (hCG) and the hexadecapeptide of the α subunit of the insulin receptor (30-55) by conventional solution methods and solid phase methods, aiming to inhibit the formation of asparagine during the synthesis of asparagyl peptides. Studies have shown that β-β-1-imidopropionic acid is an effective protector of the β-carboxyl function of aspartic acid residues.
    1-Adamantylaspartate
  • HY-W010712S1
    Fmoc-His(Trt)-OH-15N3

    		Isotope-Labeled Compounds Amino Acid Derivatives Others
    Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH (HY-W010712). Fmoc-His (Trt)-OH is a histidine derivative. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
    Fmoc-His(Trt)-OH-15N3
  • HY-P1130
    M871

    Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide

    		 Neuropeptide Y Receptor Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
    M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is an orally active and selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM, 420 nM and >10 μM for GalR2, GalR1 and GalR3 respectively. M871 relieves the mice allergic rhinitis by reducing IgE production, as well as the number of B cells in tissues. M871 can inhibit the nerve invasion of salivary adenoid cystic carcinoma (SACC) and alleviate myocardial ischemia-reperfusion injury. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain) .
    M871
  • HY-D2747
    BP Fluor 405 acid

    		Fluorescent Dye Others
    BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
    BP Fluor 405 acid

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