Search Result
Results for "
Skin wound
" in MedChemExpress (MCE) Product Catalog:
9
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-110050
-
-
-
- HY-N2551
-
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S-Methylmethionine sulfonium chloride
|
Others
|
Inflammation/Immunology
|
|
Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration .
|
-
-
- HY-NP192
-
|
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Reactive Oxygen Species (ROS)
Bacterial
|
Infection
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
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Sericin is a type of spherical protein that can be isolated from silk cocoons. Sericin is a cognitive enhancer and pain reliever. Sericin is a fetal bovine serum- or DMSO-replacing cryoprotectant agent. Sericin reduces oxidative stress and reactive oxygen species (ROS). Sericin can repair wounds by producing collagen. Sericin has antioxidant, anti-diabetic, anti-hyperlipidemic, anti-inflammatory, skin moisturizer, wound healing, antibacterial, antimicrobial, and anti-tumor protector .
|
-
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- HY-17505
-
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TCV-116
|
Angiotensin Receptor
Apoptosis
|
Cardiovascular Disease
Endocrinology
|
|
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure .
|
-
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- HY-B2170A
-
|
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Bacterial
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Infection
|
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Octenidine dihydrochloride is an effective antiseptic compound for skin mucous membranes and wounds.
|
-
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- HY-B0226A
-
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(E)-Nitrofural
|
Bacterial
Parasite
|
Infection
|
|
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .
|
-
-
- HY-162818
-
|
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Bacterial
Reactive Oxygen Species (ROS)
|
Infection
|
|
Antibacterial agent 237 (compound Ru-8) is a bacteriostatic agent for Staphylococcus aureus, with MIC of 0.78-1.56 μg/mL. Antibacterial agent 237 destroys bacterial cell membranes, changes their permeability, and induces bacteria to produce Reactive Oxygen Species, leading to bacterial death without causing drug resistance. Antibacterial agent 237 has low hemolytic toxicity to rabbit red blood cells and Raw 264.7 cells, and has significant antibacterial effects against Staphylococcus aureus in mouse skin wound infection models and Bacillus major larvae infection models .
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- HY-B2170AR
-
|
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Bacterial
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Infection
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Octenidine (dihydrochloride) (Standard) is the analytical standard of Octenidine (dihydrochloride). This product is intended for research and analytical applications. Octenidine dihydrochloride is an effective antiseptic compound for skin mucous membranes and wounds.
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- HY-172377A
-
|
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Biochemical Assay Reagents
|
Others
|
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Poly(L-lactide) (MW 10000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
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-
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- HY-172377
-
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Biochemical Assay Reagents
|
Others
|
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Poly(L-lactide) (MW 5000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
-
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- HY-172377C
-
|
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Biochemical Assay Reagents
|
Others
|
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Poly(L-lactide) (MW 40000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
-
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- HY-172377B
-
|
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Biochemical Assay Reagents
|
Others
|
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Poly(L-lactide) (MW 20000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
-
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- HY-Y0683A
-
|
|
Biochemical Assay Reagents
|
Others
|
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Petrolatum (white) is an ointment vehicle for many agents, due to its low skin irritation. Petrolatum (white) is a safe, effective wound care ointment for ambulatory surgery .
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- HY-B0614A
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Bacterial
Fungal
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Infection
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Mafenide Acetate is a potent sulfonamide antimicrobial agent. Mafenide Acetate exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide Acetate also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide Acetate can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
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- HY-P11112
-
|
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β-catenin
Wnt
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Inflammation/Immunology
|
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PTD-DBM is a competitive peptide that blocks the CXXC5-Dvl interaction and induces the expression of β-catenin, α-SMA, and type I collagen. PTD-DBM has skin wound healing activity .
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- HY-119358
-
|
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Reactive Oxygen Species (ROS)
Apoptosis
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Cardiovascular Disease
Inflammation/Immunology
|
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Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis .
|
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- HY-W415753
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VUFB-15754
|
Drug Derivative
|
Neurological Disease
Inflammation/Immunology
|
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Alaptide, a spirocyclic synthetic dipeptide and a derivative of melanocyte-stimulating hormone release-inhibiting factor (MIF), is a transdermal permeation modifier. Alaptide loaded on nanofibrous membranes accelerates the healing of skin incisions, particularly the healing of skin burns.
Alaptide is a nootropic agent, that influences the dopaminergic system and increases homovanillic acid level in the striatum of rat models. Alaptide can be used for wound healing with large damaged areas and neurological diseases research .
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- HY-P5248
-
|
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Collagen
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Metabolic Disease
|
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Tetrapeptide-1 is a signaling peptide with antioxidant properties. Tetrapeptide-1 can stimulate the synthesis of extracellular matrices (such as collagen, elastin, and fibronectin), thereby combating signs of skin aging, such as wrinkles and sagging. Tetrapeptide-1 has been reported to be used as a cosmetic ingredient .
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- HY-B0614AR
-
|
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Reference Standards
Bacterial
Fungal
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Infection
|
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Mafenide (Acetate) (Standard) is the analytical standard of Mafenide Acetate (HY-B0614A). This product is intended for research and analytical applications. Mafenide Acetate is a potent sulfonamide antimicrobial agent. Mafenide Acetate exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide Acetate also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide Acetate can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
|
-
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- HY-119358R
-
|
|
Reference Standards
Reactive Oxygen Species (ROS)
Apoptosis
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Traumatic Acid (Standard) is the analytical standard of Traumatic Acid. This product is intended for research and analytical applications. Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis[1][2].
|
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- HY-W127575
-
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delta-3,5-Cholestadiene
|
PI3K
Akt
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Inflammation/Immunology
|
|
Cholesta-3,5-diene is an inflammatory modulator that targets immune cells such as neutrophils and accelerates wound healing by promoting neutrophil chemotaxis and fibroblast migration. Cholesta-3,5-diene enhances immune cell recruitment and extracellular matrix deposition by activating chemokine receptor-mediated signaling pathways such as PI3K/Akt. Cholesta-3,5-diene can be applied topically to wound repair and has potential therapeutic value in chronic ulcers or skin lesions .
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- HY-P0063
-
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GHK-Cu
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Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .
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-
-
- HY-17505R
-
|
TCV-116 (Standard)
|
Reference Standards
Angiotensin Receptor
Apoptosis
|
Cardiovascular Disease
Endocrinology
|
|
Candesartan Cilexetil (Standard) is the analytical standard of Candesartan Cilexetil. This product is intended for research and analytical applications. Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure .
|
-
-
- HY-P0063A
-
|
GHK-Cu acetate
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Copper tripeptide (GHK-Cu) acetate is a tripeptide. During wound healing, Copper tripeptide acetate may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide acetate has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide acetate is a natural modulator of multiple cllular pathways in skin regeneration .
|
-
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- HY-P5256
-
|
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Bacterial
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Others
|
|
Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
|
-
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- HY-W707384
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-
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- HY-B1024
-
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DL-Pantothenol; DL-Pantothenyl alcohol
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Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
DL-Panthenol (DL-Pantothenol) is a precursor of pantothenic acid. DL-Panthenol easily penetrates the skin and has effects of deep moisturizing, promoting wound healing and anti-inflammation. DL-Panthenol can also be used as a hair conditioner in cosmetics. DL-Panthenol has low acute toxicity, non-sensitizing property, and no significant genotoxicity or reproductive and developmental toxicity. DL-Panthenol can be applied to the research of cosmetics .
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- HY-NP162
-
|
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Biochemical Assay Reagents
|
Others
|
|
Recombinant Humanized Type XVII Collagen is a transmembrane protein that forms hemidesmosomes. Recombinant Humanized Type XVII Collagen facilitates interactions between stem cells,surrounding cells,and the extracellular matrix,thereby regulating skin homeostasis,aging,and wound healing. Recombinant Humanized Type XVII Collagen also possesses unique cell adhesion sites and signal transduction functions,which can regulate cell migration,proliferation,and differentiation .
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-
-
- HY-B0226S
-
|
Nitrofural-13C,15N2
|
Isotope-Labeled Compounds
|
Infection
|
|
Nitrofurazone- 13C, 15N2 (Nitrofural- 13C, 15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .
|
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- HY-174985
-
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Bacterial
|
Infection
|
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Anti-MRSA agent 32 (Compound 26) is an orally active and selective SaClpP (Staphylococcus aureus ClpP protease) activator with an EC50 value of 0.98 μM. Anti-MRSA agent 32 activates SaClpP to abnormally degrade bacterial proteins, inhibiting the proliferation of Staphylococcus aureus. Anti-MRSA agent 32 promotes wound healing in a murine skin infection model. Anti-MRSA agent 32 is promising for research of infectious diseases such as methicillin-resistant Staphylococcus aureus (MRSA) infections .
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- HY-N1198
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-
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- HY-N2589
-
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TGF-β Receptor
Collagen
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Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin is a P4HA2 enzymatic agonist. Isosaponarin increases collagen synthesis via up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production, promoting skin health and wound healing. Isosaponarin-rich plants exhibit strong antimicrobial, antioxidant, anti-hyaluronidase, antiplatelet, anti-atopic dermatitis, and anti-tumor effects .
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- HY-B1057S2
-
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Fenazoxine-d3
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β-catenin
|
Neurological Disease
|
|
Nefopam-d3 is a deuterium labeled Nefopam (Fenazoxine). Nefopam is a centrally-acting but non-opioid analgesic drug, and Nefopam targets β-catenin protein level in mesenchymal cells .
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- HY-134508
-
|
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mTOR
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Cancer
|
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C24-Ceramide is an orally active competitive binding agonist of PIP4K2C (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .
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- HY-N6929
-
|
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Ferroptosis
Keap1-Nrf2
Reactive Oxygen Species (ROS)
|
Neurological Disease
Cancer
|
|
Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
|
-
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- HY-168204
-
|
|
Bacterial
Fungal
|
Infection
|
|
3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing .
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-
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- HY-N6929R
-
|
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Reference Standards
Ferroptosis
Keap1-Nrf2
Reactive Oxygen Species (ROS)
|
Neurological Disease
Cancer
|
|
Angelic acid (Standard)) is the analytical standard of Angelic acid (HY-N6929). This product is intended for research and analytical applications. Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-NP192
-
|
|
Native Proteins
|
|
Sericin is a type of spherical protein that can be isolated from silk cocoons. Sericin is a cognitive enhancer and pain reliever. Sericin is a fetal bovine serum- or DMSO-replacing cryoprotectant agent. Sericin reduces oxidative stress and reactive oxygen species (ROS). Sericin can repair wounds by producing collagen. Sericin has antioxidant, anti-diabetic, anti-hyperlipidemic, anti-inflammatory, skin moisturizer, wound healing, antibacterial, antimicrobial, and anti-tumor protector .
|
-
- HY-W127575
-
|
delta-3,5-Cholestadiene
|
Drug Delivery
|
|
Cholesta-3,5-diene is an inflammatory modulator that targets immune cells such as neutrophils and accelerates wound healing by promoting neutrophil chemotaxis and fibroblast migration. Cholesta-3,5-diene enhances immune cell recruitment and extracellular matrix deposition by activating chemokine receptor-mediated signaling pathways such as PI3K/Akt. Cholesta-3,5-diene can be applied topically to wound repair and has potential therapeutic value in chronic ulcers or skin lesions .
|
-
- HY-B1024
-
|
DL-Pantothenol; DL-Pantothenyl alcohol
|
Biochemical Assay Reagents
|
|
DL-Panthenol (DL-Pantothenol) is a precursor of pantothenic acid. DL-Panthenol easily penetrates the skin and has effects of deep moisturizing, promoting wound healing and anti-inflammation. DL-Panthenol can also be used as a hair conditioner in cosmetics. DL-Panthenol has low acute toxicity, non-sensitizing property, and no significant genotoxicity or reproductive and developmental toxicity. DL-Panthenol can be applied to the research of cosmetics .
|
-
- HY-NP162
-
|
|
Native Proteins
|
|
Recombinant Humanized Type XVII Collagen is a transmembrane protein that forms hemidesmosomes. Recombinant Humanized Type XVII Collagen facilitates interactions between stem cells,surrounding cells,and the extracellular matrix,thereby regulating skin homeostasis,aging,and wound healing. Recombinant Humanized Type XVII Collagen also possesses unique cell adhesion sites and signal transduction functions,which can regulate cell migration,proliferation,and differentiation .
|
-
- HY-134508
-
|
|
Drug Delivery
|
|
C24-Ceramide is an orally active competitive binding agonist of PIP4K2C (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .
|
-
- HY-172377A
-
|
|
Drug Delivery
|
|
Poly(L-lactide) (MW 10000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
-
- HY-172377
-
|
|
Drug Delivery
|
|
Poly(L-lactide) (MW 5000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
-
- HY-172377C
-
|
|
Drug Delivery
|
|
Poly(L-lactide) (MW 40000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
-
- HY-172377B
-
|
|
Drug Delivery
|
|
Poly(L-lactide) (MW 20000) is a polymer that can be used for orthopedic devices, dental applications, scaffolds for autologous transplanted new skin, wound coverings, vascular systems and stents .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5248
-
|
|
Collagen
|
Metabolic Disease
|
|
Tetrapeptide-1 is a signaling peptide with antioxidant properties. Tetrapeptide-1 can stimulate the synthesis of extracellular matrices (such as collagen, elastin, and fibronectin), thereby combating signs of skin aging, such as wrinkles and sagging. Tetrapeptide-1 has been reported to be used as a cosmetic ingredient .
|
-
- HY-P0063
-
|
GHK-Cu
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .
|
-
- HY-P5257
-
|
CG-EDP3
|
Peptides
|
Others
|
|
Oligopeptide-24 (CG-EDP3) is a 13 amino acids biomimetic peptide with skin repair effect. Oligopeptide-24 upregulates expression of elastin and hyaluronic acid, and increases fibroblast activity. Oligopeptide-24 can be used in cosmetics as an anti-wrinkle and firming agent .
|
-
- HY-P11112
-
|
|
β-catenin
Wnt
|
Inflammation/Immunology
|
|
PTD-DBM is a competitive peptide that blocks the CXXC5-Dvl interaction and induces the expression of β-catenin, α-SMA, and type I collagen. PTD-DBM has skin wound healing activity .
|
-
- HY-P5256
-
|
|
Bacterial
|
Others
|
|
Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P5254
-
|
|
Peptides
|
Metabolic Disease
|
|
Hexapeptide-3isa bioactive peptide with repair skin effect and has been reported used as a cosmetic ingredient .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N2551
-
|
S-Methylmethionine sulfonium chloride
|
Plants
Compositae
|
Others
|
|
Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration .
|
-
-
- HY-119358
-
-
-
- HY-P0063
-
-
-
- HY-N1198
-
-
-
- HY-N2589
-
-
-
- HY-N6929
-
|
|
Ketones, Aldehydes, Acids
Source classification
Umbelliferae
Plants
Echinacea angustifolia DC.
|
Ferroptosis
Keap1-Nrf2
Reactive Oxygen Species (ROS)
|
|
Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
|
-
-
- HY-119358R
-
-
-
- HY-N6929R
-
|
|
Ketones, Aldehydes, Acids
Source classification
Umbelliferae
Plants
Echinacea angustifolia DC.
|
Reference Standards
Ferroptosis
Keap1-Nrf2
Reactive Oxygen Species (ROS)
|
|
Angelic acid (Standard)) is the analytical standard of Angelic acid (HY-N6929). This product is intended for research and analytical applications. Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0226S
-
|
|
|
Nitrofurazone- 13C, 15N2 (Nitrofural- 13C, 15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .
|
-
-
- HY-W707384
-
|
|
|
Candesartan Cilexetil-d11 (TCV-116-d11) is deuterium labeled Candesartan Cilexetil. Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure .
|
-
-
- HY-B1057S2
-
|
|
|
Nefopam-d3 is a deuterium labeled Nefopam (Fenazoxine). Nefopam is a centrally-acting but non-opioid analgesic drug, and Nefopam targets β-catenin protein level in mesenchymal cells .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-Y0683A
-
|
|
|
Bases
|
|
Petrolatum (white) is an ointment vehicle for many agents, due to its low skin irritation. Petrolatum (white) is a safe, effective wound care ointment for ambulatory surgery .
|
-
- HY-134508
-
|
|
|
Phospholipids
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C24-Ceramide is an orally active competitive binding agonist of PIP4K2C (mTOR complex regulator), thereby activating the mTOR signaling pathway. At the same time, C24-Ceramide changes the membrane morphology by inducing the formation of a partially interlocked gel phase in the phospholipid bilayer. C24-Ceramide can promote the proliferation and migration of keratinocytes to accelerate skin wound healing and drive the proliferation and metastasis of gallbladder cancer cells. The level of C24-Ceramide in serum can be used as a diagnostic marker for gallbladder cancer .
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