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Results for "

Reverse transcriptase-IN-1

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130241
    Reverse transcriptase-IN-1

    		HIV Infection
    Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 IIIB, E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC50of 13.7 nM against HIV-1 reverse transcriptase enzyme .
    Reverse transcriptase-IN-1
  • HY-137453C
    (R,1R)-Tenofovir amibufenamide

    (R,1R)-HS-10234

    		 Drug Intermediate Others
    (R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used for the purifying a tenofovir prodrug. Tynofovir (tenofovir) is a nucleoside acids reverse transcriptase inhibitors .
    (R,1R)-Tenofovir amibufenamide
  • HY-105216
    L 697661

    		Reverse Transcriptase HIV Infection
    L 697661 is an orally active HIV-1 reverse transcriptase inhibitor .
    L 697661
  • HY-120737
    L-702007

    		HIV Infection
    L-702007 is a potent HIV-1 reverse transcriptase inhibitor .
    L-702007
  • HY-107003
    Opaviraline

    GW420867X

    		 HIV Protease Infection
    Opaviraline (GW420867X) is an anti-HIV-1 reverse transcriptase inhibitor .
    Opaviraline
  • HY-17423D
    ent-Abacavir

    		Drug Intermediate Others
    ent-Abacavir is an enantiomer of Abacavir. Abacavir is an orally active, competitive nucleoside reverse transcriptase inhibitor .
    ent-Abacavir
  • HY-169207
    NNRT-IN-5

    		Reverse Transcriptase Cancer
    NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor .
    NNRT-IN-5
  • HY-131422
    (Rac)-8-Hydroxy-efavirenz

    		Drug Metabolite Infection
    (Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz (HY-10572), a non-nucleoside HIV-1 reverse transcriptase inhibitor .
    (Rac)-8-Hydroxy-efavirenz
  • HY-129667
    BM 21.1298

    		Reverse Transcriptase HIV Infection
    BM 21.1298 is a selective and high specific nonnucleoside immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) inhibitor with antiviral activity .
    BM 21.1298
  • HY-118740
    L-708906

    		HIV Infection
    L-708906 is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an IC50 value of 12 μM. L-708906 inhibits HIV strains resistant to nonnucleoside or nucleoside reverse transcriptase inhibitors .
    L-708906
  • HY-137613C
    Rp-TTPαS tetrasodium

    		HIV Infection
    Rp-TTPαS (tetrasodium) is the Rp-isomer of TTPαS (tetrasodium). Rp-TTPαS (tetrasodium) incorporate with HIV-1 reverse transcriptase (HIV-1 RT) with HIV-1 RT with large phosphorothioate elemental effects .
    Rp-TTPαS tetrasodium
  • HY-15232S2
    Tenofovir alafenamide-d6

    GS-7340-d6

    		 Isotope-Labeled Compounds Reverse Transcriptase HIV Infection Cancer
    Tenofovir alafenamide-d6 (GS-7340-d6) is deuterium labeled Tenofovir alafenamide. Tenofovir alafenamide (GS-7340) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor .
    Tenofovir alafenamide-d6
  • HY-175363
    HIV-1-IN-84

    		HIV HIV Protease Infection
    HIV-1-IN-84 (Compound 9) is a potent HIV-1 non-nucleoside reverse transcriptase (HIV-1 RT) inhibitor (IC50=33.89 μM, EC50=540 nM). HIV-1-IN-84 is promising for research of HIV infections .
    HIV-1-IN-84
  • HY-19143
    L-697639

    		HIV Infection
    L-697639 is an inhibitor for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 20-400 nM (in a template-primer-dependent manner). L-697639 exhibits antiviral activity, that inhibits 95% HIV-1 infection at concentrations of 12-200 nM in human T lymphocyte cultures .
    L-697639
  • HY-172408
    NNRT-IN-6

    		Reverse Transcriptase HIV Infection
    NNRT-IN-6 (Compound 13a) is the non-nucleoside reverse transcriptase inhibitor (NNRT) for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 0.41 μM. NNRT-IN-6 inhibits HIV-1 wildtype and mutant strains L100I, K103N, Y181C, Y188L, E138K, F227L/V106A and RES056 with EC50 of 6.2-250 nM .
    NNRT-IN-6
  • HY-175351
    HIV-1-IN-83

    		HIV Reverse Transcriptase Infection
    HIV-1-IN-83 (Compound 18E) is a HIV-1 non-nucleoside reverse transcriptase inhibitor with an IC50 of 0.45 μM for wild-type HIV-1 non-nucleoside reverse transcriptase. HIV-1-IN-83 has potent antiviral activity against both HIV-1 wild-type and mutant strains and improves antidrug resistance for Y188L and RES056 mutant strains. HIV-1-IN-83 has no significant toxicity up to 11.088 μM .
    HIV-1-IN-83
  • HY-117725
    S-2720

    		HIV Reverse Transcriptase Infection
    S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection .
    S-2720

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