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Resveratrol

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16561
    Resveratrol
    Maximum Cited Publications
    139 Publications Verification

    trans-Resveratrol; SRT501

    		 IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2 Infection Inflammation/Immunology Cancer
    Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
    Resveratrol
  • HY-137932
    Resveratrol-3-O-sulfate sodium

    		Drug Metabolite Others
    Resveratrol-3-O-sulfate (sodium) is the metabolite of Resveratrol .
    Resveratrol-3-O-sulfate sodium
  • HY-136203
    Resveratrol analog 1

    		IKK Autophagy Mitophagy Sirtuin Inflammation/Immunology Cancer
    Resveratrol analog 1 is an analog of Resveratrol (HY-16561), compound 48. Resveratrol is a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
    Resveratrol analog 1
  • HY-16561R
    Resveratrol (Standard)
    Maximum Cited Publications
    139 Publications Verification

    trans-Resveratrol (Standard); SRT501 (Standard)

    		 Reference Standards IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2 Infection Inflammation/Immunology Cancer
    Resveratrol (Standard) is the analytical standard of Resveratrol. This product is intended for research and analytical applications. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
    Resveratrol (Standard)
  • HY-16561S
    Resveratrol-d4

    trans-Resveratrol-d4; SRT501-d4

    		 Isotope-Labeled Compounds IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2 Infection Inflammation/Immunology Cancer
    Resveratrol-d4 is the deuterium labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
    Resveratrol-d4
  • HY-136204
    Resveratrol analog 2

    		IKK Autophagy Mitophagy Sirtuin Inflammation/Immunology Cancer
    Resveratrol analog 2 is an analog of Resveratrol (HY-16561). Resveratrol is a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties .
    Resveratrol analog 2
  • HY-16561G
    Resveratrol

    trans-Resveratrol; SRT501

    		 IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Keap1-Nrf2 Infection Inflammation/Immunology Cancer
    Resveratrol (GMP) is Resveratrol (HY-16561) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
    Resveratrol
  • HY-144159S
    Resveratrol 3,5-diglucuronide-d4

    		Isotope-Labeled Compounds Others
    Resveratrol 3,5-diglucuronide-d4 is the deuterium labeled Resveratrol 3,5-diglucuronide .
    Resveratrol 3,5-diglucuronide-d4
  • HY-144158S
    Resveratrol 3-sulfate-d4 triethylamine

    		Isotope-Labeled Compounds Others
    Resveratrol 3-sulfate-d4 (triethylamine) is the deuterium labeled Resveratrol 3-sulfate triethylamine .
    Resveratrol 3-sulfate-d4 triethylamine
  • HY-16561S1
    Resveratrol-13C6

    trans-Resveratrol-13C6; SRT501-13C6

    		 Isotope-Labeled Compounds IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2 Infection Inflammation/Immunology Cancer
    Resveratrol- 13C6 is the 13C-labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
    Resveratrol-13C6
  • HY-137912S1
    Resveratrol-3-O-beta-D-glucuronide-13C6

    		Isotope-Labeled Compounds Others
    Resveratrol-3-O-beta-D-glucuronide- 13C6 is deuterium labeled trans-Resveratrol-3-O-β-D-Glucuronide.
    Resveratrol-3-O-beta-D-glucuronide-13C6
  • HY-N11790
    Resveratrol-4′-O-(6′′-O-galloyl)-glucopyranoside

    		Others Others
    Resveratrol-4′-O-(6′′-O-galloyl)-glucopyranoside is a polyphenol glycoside which can be isolated from Rheum tanguticum Maxim .
    Resveratrol-4′-O-(6′′-O-galloyl)-glucopyranoside
  • HY-N4195
    Resveratroloside
    2 Publications Verification

    Resveratrol glycoside; trans-Resveratrol 4'-O-β-D-glucopyranoside

    		 Glycosidase Cardiovascular Disease Metabolic Disease
    Resveratroloside (Resveratrol glycoside) is an orally active competitive inhibitor of α-glucosidase. Resveratroloside has hypoglycemic and cardioprotective effects. Resveratroloside can be used for the research of diabetes and heart system diseases .
    Resveratroloside
  • HY-N1408
    trans-Trimethoxyresveratrol

    trans-trismethoxy Resveratrol; (E)-Resveratrol trimethyl ether; trans-3,5,4'-Trimethoxystilbene

    		 VEGFR Reactive Oxygen Species (ROS) Caspase Apoptosis Inflammation/Immunology Cancer
    Trans-Trimethoxyresveratrol (trans-trismethoxy Resveratrol; (E)-Resveratrol trimethyl ether; trans-3,5,4'-Trimethoxystilbene) is an orally active natural derivative of Resveratrol (HY-16561). Trans-Trimethoxyresveratrol has an enhanced anticancer profile compared to Resveratrol, exhibiting higher potency than resveratrol, with improved cancer cell proliferation inhibition, induction of cell cycle arrest, decreased metastasis, and increased apoptosis. Trans-Trimethoxyresveratrol causes microtubule disassembling and tubulin depolymerization and exerts anti-angiogenic effects through VEGFR2. Trans-Trimethoxyresveratrol can be used for the studies of anti-angiogenic and anti-cancer (such as non-small cell lung cancer and osteosarcoma) .
    trans-Trimethoxyresveratrol
  • HY-137912
    trans-Resveratrol-3-O-β-D-Glucuronide

    		Drug Metabolite Endocrinology Cancer
    trans-Resveratrol-3-O-β-D-Glucuronide is an active metabolite of trans-resveratrol. trans-Resveratrol-3-O-β-D-Glucuronide reduces the proliferation of several intestinal cancer cell line. trans-Resveratrol-3-O-β-D-Glucuronide increases pyruvate production in livers .
    trans-Resveratrol-3-O-β-D-Glucuronide
  • HY-118634
    trans-Resveratrol-4'-O-D-Glucuronide

    R-4G

    		 FATP Metabolic Disease
    Trans-Resveratrol-4'-O-D-Glucuronide (R-4G) is a metabolite of resveratrol with anti-fat accumulation property, and can be used for metabolic research .
    trans-Resveratrol-4'-O-D-Glucuronide
  • HY-159734
    TPP-resveratrol

    		Apoptosis Cancer
    TPP-resveratrol is a conjugate of Resveratrol (HY-16561) and triphenylphosphine (TPP) with anticancer activity. TPP-resveratrol increases the potency of Resveratrol through mitochondrial-targeted delivery and induces mitochondria-mediated apoptosis .
    TPP-resveratrol
  • HY-16561S2
    (E/Z)-Resveratrol-13C6

    		Isotope-Labeled Compounds Cancer
    Resveratrol-(4-Hydroxyphenyl)- 13CN6 is the 13C labeled Resveratrol-(4-Hydroxyphenyl) .
    (E/Z)-Resveratrol-13C6
  • HY-16561A
    cis-Resveratrol
    1 Publications Verification

    		 Enterovirus NF-κB Infection Inflammation/Immunology
    cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC50s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively. cis-Resveratrol is the inhibitor for NF-κB signaling pathway .
    cis-Resveratrol
  • HY-W034097S
    trans-Trismethoxy Resveratrol-d4

    		Isotope-Labeled Compounds Others
    trans-Trismethoxy Resveratrol-d4 is the deuterium labeled trans-Trismethoxy Resveratrol .
    trans-Trismethoxy Resveratrol-d4
  • HY-131327
    Azo-resveratrol

    		Tyrosinase Cancer
    Azo-resveratrol, an Azo compound, inhibits Mushroom tyrosinase (IC50=36.28 μM).
    Azo-resveratrol
  • HY-124113
    4'-Bromo-resveratrol

    4′‐BR

    		 Sirtuin Apoptosis Cancer
    4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling .
    4'-Bromo-resveratrol
  • HY-121989
    cis-Trismethoxy resveratrol

    (Z)-3,5,4'-Trimethoxystilbene

    		 Microtubule/Tubulin Cancer
    Cis-trismethoxy resveratrol is a potent anti-mitotic reagent.Cis-trismethoxy resveratrol inhibits tubulin polymerization with an IC50 value of 4 μM .
    cis-Trismethoxy resveratrol
  • HY-N9867
    Gnetifolin E

    		TNF Receptor Inflammation/Immunology
    Gnetifolin E is a resveratrol trimer derivative that can be isolated from Gnetum brunonianum. Gnetifolin E has anti-inflammatory activity, and inhibits TNF-α .
    Gnetifolin E
  • HY-118634S
    trans-Resveratrol-4'-O-D-Glucuronide-d4

    R-4G-d4

    		 Isotope-Labeled Compounds Others
    trans-Resveratrol-4'-O-D-Glucuronide-d4 (R-4G-d4) is deuterium labeled trans-Resveratrol-4'-O-D-Glucuronide.
    trans-Resveratrol-4'-O-D-Glucuronide-d4
  • HY-N10766
    Ampelopsin F

    		Others Others
    Ampelopsins F is a bridged plant oligostilbene that can be isolated from Ampelopsis brevipedunculata var. hancei roots. Ampelopsins F is a resveratrol dimer .
    Ampelopsin F
  • HY-N1410
    Triacetylresveratrol

    		STAT NF-κB Cancer
    Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects .
    Triacetylresveratrol
  • HY-N1410R
    Triacetylresveratrol (Standard)

    		STAT NF-κB Cancer
    Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects .
    Triacetylresveratrol (Standard)
  • HY-137977
    DMU-212
    2 Publications Verification

    		 ERK Apoptosis Cancer
    DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active .
    DMU-212
  • HY-129156
    HS-1793

    		Apoptosis Cancer
    HS-1793 is a Resveratrol (HY-16561) analogue with antitumor activities in a variety of cancer cell lines . HS-1793 induces cell apoptosis .
    HS-1793
  • HY-124529
    Lunularin

    		Endogenous Metabolite 11β-HSD Inflammation/Immunology Cancer
    Lunularin (Compound 3), a monoterpene, is a metabolite of gut microbiota-derived Resveratrol (HY-16561). Lunularin can be isolated from the liverwort Conocephalum conicum. Lunularin is a selective 11β-HSD1 inhibitor with IC50s of 45.44 and 17.39  μM for human 11β-HSD1 and rat 11β-HSD1, respectively. Lunularin has significant anti-inflammatory and anti-cancer activities .
    Lunularin
  • HY-161867
    Platelet aggregation-IN-1

    		Thrombin Others
    Platelet aggregation-IN-1 (Compound 10e) is an inhibitor for platelet aggregation, that inhibits 100% thrombin-induced platalet aggregation at 50 μM .
    Platelet aggregation-IN-1
  • HY-144635
    Nrf2-ARE/hMAO-B/QR2 modulator 1

    		Monoamine Oxidase Keap1-Nrf2 Reactive Oxygen Species (ROS) Neurological Disease
    Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC50s of 8.05, 9.83 and 0.57 μM for hMAO-B, NRF2 and QR2. Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated mice hippocampal slices . Nrf2-ARE/hMAO-B/QR2 modulator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Nrf2-ARE/hMAO-B/QR2 modulator 1
  • HY-112554
    PDM11

    		Phosphatase Others
    PDM11 is a derivative of antioxidant resveratrol. PDM11 do not exhibit any significant protective effect against oxidation of linoleate micelles initiated by radiolysis-generated hydroxyl radicals. PDM11 is inactive in resveratrol activity assays .
    PDM11
  • HY-N3841A
    δ-Viniferin

    		Cytochrome P450 Metabolic Disease
    δ-Viniferin is a resveratrol dehydrodimer, an isomer of ε-Viniferin (HY-N3841) . ε-Viniferin (epsilon-Viniferin), the dimer of Resveratrol, displays a potent inhibitory for all the CYP activities, with Ki values from 0.5-20 μM. ε-Viniferin possesses potent antioxidant, anti-inflammatory, anti-diabetic, and anti-neurodegenerative capacity.
    δ-Viniferin
  • HY-N3059
    Pinostilbene
    3 Publications Verification

    trans-Pinostilbene

    		 Drug Metabolite Neurological Disease Cancer
    Pinostilbene (trans-Pinostilbene) is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells .
    Pinostilbene
  • HY-N3059R
    Pinostilbene (Standard)

    trans-Pinostilbene (Standard)

    		 Drug Metabolite Reference Standards Neurological Disease Cancer
    Pinostilbene (Standard) is the analytical standard of Pinostilbene. This product is intended for research and analytical applications. Pinostilbene (trans-Pinostilbene) is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells .
    Pinostilbene (Standard)
  • HY-173463
    Sirtuin modulator 8

    		Sirtuin Metabolic Disease Inflammation/Immunology
    Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases .
    Sirtuin modulator 8
  • HY-N2387
    Pinosylvin

    		Bacterial Apoptosis Autophagy Infection Cancer
    Pinosylvin is a?pre-infectious stilbenoid toxin?isolated from the heartwood of Pinus species, has anti-bacterial activities . Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells .
    Pinosylvin
  • HY-126241
    RV01

    		Aldehyde Dehydrogenase (ALDH) Inflammation/Immunology
    RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .
    RV01
  • HY-N15473
    Isopaucifloral F

    (±)-Isopaucifloral F

    		 Estrogen Receptor/ERR Drug Derivative Inflammation/Immunology
    Isopaucifloral F ((±)-Isopaucifloral F) is a Resveratrol (HY-16561)-derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC50: 46.96 μM). Isopaucifloral F has antiosteoporosis activity. LD50 in rats: > 5 mg/kg .
    Isopaucifloral F
  • HY-162170
    Anti-inflammatory agent 72

    		NF-κB Keap1-Nrf2 p38 MAPK Inflammation/Immunology
    Anti-inflammatory agent 72 (compound 5) is a novel resveratrol derivative hybrid with benzoylhydrazine. Anti-inflammatory agent 72 shows anti-inflammatory and antioxidant activities by activating Nrf2 and inhibiting NF-κB p65/iNOS and MAPKs signaling pathways .
    Anti-inflammatory agent 72
  • HY-N2387R
    Pinosylvin (Standard)

    		Reference Standards Bacterial Apoptosis Autophagy Infection Cancer
    Pinosylvin (Standard) is the analytical standard of Pinosylvin. This product is intended for research and analytical applications. Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities . Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells .
    Pinosylvin (Standard)
  • HY-N3841
    ε-​Viniferin
    1 Publications Verification

    epsilon-Viniferin

    		 Cytochrome P450 Neurological Disease Metabolic Disease Inflammation/Immunology
    ε-Viniferin (epsilon-Viniferin), the dimer of Resveratrol and can be isolated from Vitis vinifera, displays a potent inhibitory for all the CYP activities, with Ki values from 0.5-20 μM. ε-Viniferin possesses potent antioxidant, anti-inflammatory, anti-diabetic, and anti-neurodegenerative capacity .
    ε-​Viniferin
  • HY-124037
    SRT 1460
    5 Publications Verification

    		 Sirtuin Cancer
    SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues .
    SRT 1460
  • HY-168068
    Res-Glu3

    		Others Neurological Disease
    Res-Glu3 is the derivative of Resveratrol (HY-16561). Res-Glu3 mitigates the ROS accumulation, and exhibits neuroprotective efficacy against H2O2-caused cellular damage in PC12. Res-Glu3 exhibits antioxidant activity in rats ischemia reperfusion models .
    Res-Glu3
  • HY-142026
    Vitisin A

    (+)-Vitisin A

    		 NF-κB ERK Inflammation/Immunology
    Vitisin A has antioxidative, anticancer, antiapoptotic, neuroprotective and anti-inflammatory effects. Vitisin A inhibits LPS-induced NO and iNOS production via down-regulation of ERK1/2 and p38 and the NF-κB signal pathway. Vitisin A also inhibits adipocyte differentiation. Vitisin A is a resveratrol tetramer that can be isolated from Vitis vinifera roots .
    Vitisin A
  • HY-129133
    cis-Miyabenol C

    		Drug Isomer Others
    cis-Miyabenol C is an isomer of the resveratrol trimer Miyabenol C, which can be isolated from grape herbs. Miyabenol C is an inhibitor of β-amyloid (Aβ) and amyloid β precursor protein (APP) in Alzheimer's disease model mice, and inhibit β-secretase activity without changing the protein level of β-secretase BACE1 .
    cis-Miyabenol C
  • HY-N2229
    Rhapontigenin
    2 Publications Verification

    		 Cytochrome P450 Fungal Bacterial Infection Inflammation/Immunology Cancer
    Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50  = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively .
    Rhapontigenin
  • HY-N3540
    Caraphenol A

    		Others Inflammation/Immunology
    Caraphenol A is a resveratrol trimer and is able to transiently reduce interferon-induced transmembrane (IFITM) protein expression. Caraphenol A safely enhances lentiviral vector gene delivery to hematopoietic stem and progenitor cells . Caraphenol A also inhibits human cystathionine β-synthase (hCBS) and human cystathionine γ- lyase (hCSE) with IC50s of 5.9 μM and 12.1 μM, respectively .
    Caraphenol A

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