2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. Sirtuin modulator 8

Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases.

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Sirtuin modulator 8

Sirtuin modulator 8 Chemical Structure

CAS No. : 925437-38-3

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500 μg In-stock

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Based on 1 publication(s) in Google Scholar

Sirtuin modulator 8 Related Antibodies

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Description

Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases[1].

In Vitro

Sirtuin modulator 8 (Compound 2) (2 μM) causes a significant decrease in MCP-1 expression in a human leukocyte (WBC) model, indicating its potential to inhibit inflammatory responses[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sirtuin modulator 8 Related Antibodies
Molecular Weight

483.59

Formula

C26H25N7OS
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=NC2=CC=CC=C2N=C1)NC3=C(C4=CN5C(CN6CCC(CC6)N)=CSC5=N4)C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Sirtuin modulator 8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sirtuin modulator 8925437-38-3Sirtuin modulator8Sirtuin modulator-8SirtuinsirtuinWBCResveratrolagingInhibitorinhibitorinhibit

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