Search Result
Results for "
PEG5 linker
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-116006
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PROTAC linker 36
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PROTAC Linkers
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Cancer
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Bis-PEG5-acid (PROTAC Linker 36) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. Bis-PEG5-acid (PROTAC Linker 36) can be used in the synthesis of the CP5V. CP5V is a PROTAC, and specifically degrades Cdc20 .
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- HY-W022240
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PROTAC linker 17
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PROTAC Linkers
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Cancer
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NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-130271
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VH032-PEG5-COOH; VHL Ligand-linker Conjugates 16; E3 Ligase Ligand-linker Conjugates 58
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology .
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- HY-126889
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-131647
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Pomalidomide-PEG5-CO2H
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology .
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- HY-23417
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PROTAC Linkers
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Cancer
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PEG5-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-129637
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PROTAC Linkers
ADC Linker
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Cancer
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NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130601
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- HY-W592008
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Biochemical Assay Reagents
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Others
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C18-PEG5-Acid is a hybrid linker featuring a hydrophobic C18 chain and hydrophilic PEG5 spacer with a carboxylic acid. The carboxylic acid is reactive with amines to form a stable amide bond.
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-
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- HY-116186
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG5-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-120845
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- HY-101157
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-120702
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ADC Linker
PROTAC Linkers
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Cancer
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N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-139333
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC .
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- HY-126976
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141296
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PROTAC Linkers
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Cancer
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PEG5-bis-(Ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-112495
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HaloPROTAC 2
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
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- HY-130388
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-126885
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ADC Linker
PROTAC Linkers
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Cancer
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DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-130150
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PROTAC Linkers
ADC Linker
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Inflammation/Immunology
Cancer
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m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-succinimidyl carbonate is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-115384
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-133193
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PROTAC Linkers
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Infection
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Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity . Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-159777
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- HY-138403
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PROTAC Linkers
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Cancer
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THP-C1-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138529
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PROTAC Linkers
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Cancer
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Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138528
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PROTAC Linkers
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Cancer
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Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141055
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PROTAC Linkers
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Cancer
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Cy5-PEG5-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133006
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PROTAC Linkers
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Cancer
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Fluorescein-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W040195
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PROTAC Linkers
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Cancer
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m-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-126962
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PROTAC Linkers
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Cancer
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Mal-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-133062
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ADC Linker
PROTAC Linkers
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Cancer
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Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-120537
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W190936
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Thalidomide-O-PEG5-Tosyl is a molecule that incorporatess the Thalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. Thalidomide-O-PEG5-tosyl is reactive with nucleophiles such as amine, hydroxy containing molecules.
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- HY-140483
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PROTAC Linkers
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Cancer
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Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-129622
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PROTAC Linkers
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Cancer
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NH2-PEG5-C6-Cl (K-7) is a linker which refers to the PEG composition. NH2-PEG5-C6-Cl can be used in the synthesis of a series of compounds that induce degradation of intracellular molecules by autophagy .
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- HY-133384
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PROTAC Linkers
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Cancer
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SPDP-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133051
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PROTAC Linkers
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Cancer
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Hydroxy-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140549
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PROTAC Linkers
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Cancer
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NH-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W108220
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-130657
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PROTAC Linkers
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Cancer
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m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-138487
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W190962
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PROTAC Linkers
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Cancer
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BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133290
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HS-PEG5-CH2CH2COOH
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PROTAC Linkers
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Cancer
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Thiol-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130895
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PROTAC Linkers
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Cancer
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Bis-Mal-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W042714
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PROTAC Linkers
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Cancer
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BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W096131
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PROTAC Linkers
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Cancer
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Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096160
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PROTAC Linkers
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Cancer
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Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133065
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PROTAC Linkers
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Cancer
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m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W096161
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PROTAC Linkers
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Cancer
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Bis-methacrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W042501
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PROTAC Linkers
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Cancer
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m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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- HY-141214
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PROTAC Linkers
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Cancer
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141283
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-122459
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PROTAC Linkers
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Cancer
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Fmoc-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141095
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PROTAC Linkers
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Cancer
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Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138378
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138385
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PROTAC Linkers
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Cancer
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MS-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141298
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PROTAC Linkers
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Cancer
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Bromo-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132070
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Folic acid-PEG5-Mal
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PROTAC Linkers
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Cancer
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FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140965
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PROTAC Linkers
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Cancer
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Mal-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141408
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PROTAC Linkers
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Cancer
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m-PEG5-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-W096075
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141269
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141366
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PROTAC Linkers
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Cancer
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Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140171
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PROTAC Linkers
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Cancer
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m-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141093
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PROTAC Linkers
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Cancer
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Pyrene-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133352
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PROTAC Linkers
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Cancer
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Mal-PEG5-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096157
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PROTAC Linkers
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Cancer
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140751
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140008
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PROTAC Linkers
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Cancer
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DOTA-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140175
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PROTAC Linkers
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Cancer
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Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141275
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140749
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PROTAC Linkers
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Cancer
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BnO-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140754
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PROTAC Linkers
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Cancer
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Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141082
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PROTAC Linkers
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Cancer
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Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141308
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PROTAC Linkers
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Cancer
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m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126917
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PROTAC Linkers
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Cancer
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140743
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PROTAC Linkers
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Cancer
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Benzyl-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135921
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PROTAC Linkers
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Cancer
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m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133272
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PROTAC Linkers
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Cancer
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m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133210
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PROTAC Linkers
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Cancer
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Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-143832
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PROTAC Linkers
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Cancer
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Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096105
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PROTAC Linkers
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Cancer
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Nonylbenzene-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138728
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PROTAC Linkers
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Cancer
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Mal-amido-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133293
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HS-PEG5-OH
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PROTAC Linkers
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Cancer
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Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141094
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PROTAC Linkers
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Cancer
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Pyrene-PEG5-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140169
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PROTAC Linkers
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Cancer
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Carboxy-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138373
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PROTAC Linkers
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Cancer
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Boc-PEG5-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141375
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PROTAC Linkers
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Cancer
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m-PEG5-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-138330
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PROTAC Linkers
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Cancer
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Fmoc-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126999
-
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PROTAC Linkers
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Cancer
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Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W040245
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PROTAC Linkers
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Cancer
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Fmoc-amino-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141396
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PROTAC Linkers
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Cancer
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m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141374
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PROTAC Linkers
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Cancer
|
|
Bromo-PEG5-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140194
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140512
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-TEMPO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130523
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140267
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-145736
-
|
|
Drug-Linker Conjugates for ADC
Apoptosis
|
Cancer
|
|
β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 has antitumor activity .
|
-
- HY-145736A
-
|
|
Drug-Linker Conjugates for ADC
Apoptosis
|
Cancer
|
|
β-Glucuronide-dPBD-PEG5-NH2 TFA is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD.β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2 TFA, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 TFA can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 TFA has antitumor activity .
|
-
- HY-130330
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130147
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156490
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-140384
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141301
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140485
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140428
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138732
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134709
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141305
-
|
|
PROTAC Linkers
|
Cancer
|
|
Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141312
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141191
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130447
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-amine is a PEG-based (5 units) PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140935
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141276
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140553
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134738
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetamide-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140629
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138748
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126888
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-138719
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140302
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140958
-
|
|
PROTAC Linkers
|
Cancer
|
|
DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-132043
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140046
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138736
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-135938
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129622A
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136140
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133475
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133467
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG5-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140053
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-148662
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-140880
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140275
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140251
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141406
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-134681
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134688
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetamide-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140896
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2420
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-Mal is a PROTAC linker, belonging to the PEG class. It can be used for the synthesis of PROTAC molecules .
|
-
- HY-140225
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140392
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130551
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-171559
-
|
|
PROTAC Linkers
|
Others
|
|
TCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG5-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups .
|
-
- HY-130489
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130211
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-156170
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-5-NH-PEG5-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-NH-PEG5-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
|
-
- HY-140810
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-(Azido-PEG5-amino)propanol is a PEG linker which contains an azide moiety and a hydroxyl group. 3-(Azido-PEG5-amino)propanol is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.
|
-
- HY-133463
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-Ph-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-134750
-
|
|
PROTAC Linkers
|
Cancer
|
|
HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130577
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140366
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133070
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140481
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134678
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propanol-PEG5-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133544
-
|
|
ADC Linker
|
Cancer
|
|
Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-144080
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140489
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141243
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133340
-
|
|
PROTAC Linkers
|
Cancer
|
|
H2N-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-164785
-
|
|
Others
|
Others
|
|
TCO-PEG5-C2-Mal is a heterobifunctional linker that can be used for tetrazine ligation and sulfhydryl conjugation .
|
-
- HY-141210
-
|
Hydroxy-PEG5-t-butyl acetate
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138773
-
-
- HY-134679
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-C1-PEG5-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130572
-
|
|
PROTAC Linkers
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126381
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-135919
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140314
-
|
|
PROTAC Linkers
|
Cancer
|
|
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130945
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-125541
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138784
-
-
- HY-138784A
-
-
- HY-138375
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140537
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141059
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cy5-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Cy5-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133816A
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-amino-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .
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-
- HY-133816
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .
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-
- HY-134682
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PROTAC Linkers
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Cancer
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|
Fmoc-NH-PEG5-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-W096140
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PROTAC Linkers
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Cancer
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Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-136054
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ADC Linker
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Cancer
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N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140753
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PROTAC Linkers
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Cancer
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|
DOTA-(t-butyl)3-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-(t-butyl)3-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-163549
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-
- HY-W096092
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PROTAC Linkers
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Cancer
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BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-141037
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PROTAC Linkers
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Cancer
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N-(m-PEG9)-N'-(PEG5-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-W043840
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PROTAC Linkers
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Cancer
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|
m-PEG5-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-W022232
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PROTAC Linkers
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Cancer
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|
Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
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-
- HY-140954
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PROTAC Linkers
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Cancer
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|
DSPE-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138738
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PROTAC Linkers
|
Cancer
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|
Propargyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140826
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PROTAC Linkers
|
Cancer
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Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromoacetamido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140744
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PROTAC Linkers
|
Cancer
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|
Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140752
-
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|
PROTAC Linkers
|
Cancer
|
|
DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138516
-
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|
PROTAC Linkers
|
Cancer
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|
CG-PEG5-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . CG-PEG5-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140778
-
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|
PROTAC Linkers
|
Cancer
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|
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140214
-
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140795
-
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|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140856
-
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|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130507
-
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|
PROTAC Linkers
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Cancer
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|
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133174
-
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|
PROTAC Linkers
|
Cancer
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|
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130168
-
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PROTAC Linkers
|
Cancer
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|
m-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-133392
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PROTAC Linkers
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Cancer
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|
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134687
-
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PROTAC Linkers
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Cancer
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|
Iodoacetamide-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140757
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PROTAC Linkers
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Cancer
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|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140159
-
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|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methylamino-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140634
-
|
|
ADC Linker
|
Cancer
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|
Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130872
-
|
Thiol-PEG5-amine
|
PROTAC Linkers
|
Cancer
|
|
HS-PEG5-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130194
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140837
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140434
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140769
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-succinimidyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132093
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-S-methyl ethanethioate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132111
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140352
-
|
|
ADC Linker
|
Cancer
|
|
Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130420
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130872A
-
|
Thiol-PEG5-amine hydrochloride
|
PROTAC Linkers
|
Cancer
|
|
HS-PEG5-CH2CH2NH2 hydrochloride is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules.
|
-
- HY-141040
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-methyl-N'-methyl-O-(m-PEG4)-O'-(acid-PEG5)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190985
-
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Biochemical Assay Reagents
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Others
|
|
AZD-PEG5-methyl ester is a PEG linker containing an AZD group and a methyl ester group which can be hydrolyzed under strong basic condition. The hydrophilic PEG spacer increases solubility in aqueous media.
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-
- HY-131959
-
-
- HY-141150
-
|
|
ADC Linker
|
Cancer
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|
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-172720
-
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|
Biochemical Assay Reagents
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Others
|
|
Azide-PEG5-Ms serves as a PEG linker containing an azide that reacts with BCN, DBCO, alkyne via Click Chemistry and mesyl group that is a good leaving group for nucleophilic substitution reactions. The PEG spacer imparts water solubility.
|
-
- HY-140766
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W800688
-
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|
Biochemical Assay Reagents
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Others
|
|
Acid-PEG5-Amide-Tri(3-methoxypropanamide-PEG4-Azide) Methane is a branched PEG linker with a terminal carboxylic acid group and three terminal azides. The azide groups enables PEGylation via Click Chemistry.
|
-
- HY-W096068
-
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Biochemical Assay Reagents
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Others
|
|
Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.
|
-
- HY-130693
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130879
-
|
|
PROTAC Linkers
|
Cancer
|
|
HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HS-PEG5-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130957
-
|
|
ADC Linker
|
Cancer
|
|
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-137340
-
|
|
PROTACs
|
Cancer
|
|
WH-10417-099 is a CRBN-type PROTAC multi-kinase degrader that can jointly induce the degradation of the largest number of unique kinases (more than 125 unique kinases). WH-10417-099 induces protein degradation through the ubiquitin biotinylation (E-STUB) pathway and consists of the target protein ligand (red part) PI3Kγ ligand 1 (HY-168319), the E3 ubiquitin ligase ligand (blue part) Thalidomide 4-fluoride (HY-41547) and the PROTAC linker (black part) Amino-PEG5-C2-acid (HY-115384). The E3 ligase ligand and linker can form a conjugate Pomalidomide 4'-PEG5-acid (HY-131647).
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-
- HY-W800803
-
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|
Biochemical Assay Reagents
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Others
|
|
Mal-PEG5-NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond.
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-
- HY-W190950
-
|
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Biochemical Assay Reagents
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Others
|
|
AZD-PEG5-PFP is a PEG linker containing an AZD group and a PFP ester group, an activated ester that reacts with primary amines to form amide bonds. PFP ester has been found to be more stable than other amine reactive groups because it is less likely to undergo hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-176536
-
|
VH032-CO-(CH2)2-(O-CH2-CH2)5-azide
|
PROTAC Linkers
|
Cancer
|
|
(S,R,S)-AHPC-amide-PEG5-C2-azide (VH032-CO-(CH2)2-(O-CH2-CH2)5-azide) is a PROTAC linker that can be used to design PROTACs .
|
-
- HY-W800654
-
|
|
Biochemical Assay Reagents
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Others
|
|
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W460275
-
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|
Biochemical Assay Reagents
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Others
|
|
t-Boc-N-Amido-PEG5-Tos is a PEG linker containing a tosyl group and Boc-protected amine group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.
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-
- HY-W800670
-
|
|
Biochemical Assay Reagents
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Others
|
|
Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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-
- HY-W800813
-
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|
Biochemical Assay Reagents
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Others
|
|
Carboxy-Amido-PEG5-N-Boc is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-140822
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140821
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-172265
-
|
|
PROTACs
|
Cancer
|
|
FKBP12 PROTAC FM4 is a PROTAC degrader of MTH1, with a DC50 values of 0.09–0.22 nM. FKBP12 PROTAC FM4 is composed of PROTAC target protein ligand AP1867-3-(aminoethoxy) (HY-129363) (red part), E3 ligase ligand MTH1 ligand 1 (HY-134724) (blue part) and PROTAC Linker t-Boc-N-amido-PEG5-acetic acid (HY-W190962) (black part), among which the conjugate of PROTAC target protein ligand + Linker is FKBP12 Ligand-Linker Conjugate 2 (HY-172266) .
|
-
- HY-155643
-
|
|
PROTACs
Glutaminase
|
Cancer
|
|
PROTAC TG2 degrader-1 (compound 11) is a von Hippel-Lindau (VHL)-based PROTAC targeting tissue transglutaminase (TG2) with a KD of 68.9 μM. PROTAC TG2 degrader-1 reduces TG2 in ovarian cancer cells in a proteasome-dependent manner .
|
-
| Cat. No. |
Product Name |
Type |
| Cat. No. |
Product Name |
Type |
-
- HY-130601
-
|
Bis-PEG5-thiol
|
3D Bioprinting
|
|
Thiol-PEG5-thiol (Bis-PEG5-thiol) is a bifunctional thiol cross-linker agent.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-101157
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
|
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126976
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
|
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130388
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126885
-
|
|
|
PROTAC Synthesis
DBCO
ADC Synthesis
|
|
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133193
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity . Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141269
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-139333
-
|
|
|
Azide
|
|
Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-159777
-
|
|
|
Alkynes
|
|
CPI-203-PEG5-Alkyne is a conjugate of E3 ligase and linker. CPI-203-PEG5-Alkyne can be used for synthesis of PROTAC BRD4-DCAF1 degrader-1 (HY-169151) .
|
-
- HY-141283
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141095
-
|
|
|
Alkynes
|
|
Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141275
-
|
|
|
Alkynes
Tetrazine
|
|
Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140267
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130147
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156490
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-141276
-
|
|
|
Tetrazine
Alkynes
|
|
Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138719
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140302
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140958
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-132043
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140046
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138736
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136140
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133475
-
|
|
|
PROTAC Synthesis
TCO
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133467
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG5-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140053
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140880
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140275
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130551
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130211
-
|
|
|
ADC Synthesis
Azide
PROTAC Synthesis
|
|
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140810
-
|
|
|
Azide
|
|
3-(Azido-PEG5-amino)propanol is a PEG linker which contains an azide moiety and a hydroxyl group. 3-(Azido-PEG5-amino)propanol is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.
|
-
- HY-133463
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-Ph-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130572
-
|
|
|
ADC Synthesis
Azide
PROTAC Synthesis
|
|
Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140314
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130945
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-125541
-
|
|
|
ADC Synthesis
DBCO
PROTAC Synthesis
|
|
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141059
-
|
|
|
Azide
PROTAC Synthesis
|
|
Cy5-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Cy5-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W096140
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136054
-
|
|
|
Azide
ADC Synthesis
|
|
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140753
-
|
|
|
PROTAC Synthesis
Azide
|
|
DOTA-(t-butyl)3-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-(t-butyl)3-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140954
-
|
|
|
Azide
PROTAC Synthesis
|
|
DSPE-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138738
-
|
|
|
Azide
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140826
-
|
|
|
PROTAC Synthesis
Azide
|
|
Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromoacetamido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140744
-
|
|
|
PROTAC Synthesis
Azide
|
|
Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140752
-
|
|
|
PROTAC Synthesis
Azide
|
|
DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138516
-
|
|
|
Azide
PROTAC Synthesis
|
|
CG-PEG5-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . CG-PEG5-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140778
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140214
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140795
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140856
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130507
-
|
|
|
Azide
PROTAC Synthesis
|
|
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-133174
-
|
|
|
PROTAC Synthesis
Azide
|
|
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130168
-
|
|
|
Azide
PROTAC Synthesis
|
|
m-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-133392
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-134687
-
|
|
|
Azide
PROTAC Synthesis
|
|
Iodoacetamide-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140757
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Azide
PROTAC Synthesis
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Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140159
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Azide
PROTAC Synthesis
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Methylamino-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methylamino-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140634
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ADC Synthesis
Azide
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Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130194
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Azide
PROTAC Synthesis
ADC Synthesis
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Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140837
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Azide
PROTAC Synthesis
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Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140434
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Azide
PROTAC Synthesis
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t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140769
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Azide
PROTAC Synthesis
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Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-succinimidyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132093
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PROTAC Synthesis
Azide
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Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-S-methyl ethanethioate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132111
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Azide
PROTAC Synthesis
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Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140352
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ADC Synthesis
Azide
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Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130420
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Azide
PROTAC Synthesis
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Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-141150
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Azide
ADC Synthesis
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Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140766
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Azide
PROTAC Synthesis
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Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W096068
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Alkynes
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Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.
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- HY-130693
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PROTAC Synthesis
Azide
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Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130879
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PROTAC Synthesis
Azide
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HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HS-PEG5-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130957
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ADC Synthesis
Azide
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Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-176536
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VH032-CO-(CH2)2-(O-CH2-CH2)5-azide
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Azide
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(S,R,S)-AHPC-amide-PEG5-C2-azide (VH032-CO-(CH2)2-(O-CH2-CH2)5-azide) is a PROTAC linker that can be used to design PROTACs .
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- HY-140822
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Azide
PROTAC Synthesis
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Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140821
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Azide
PROTAC Synthesis
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Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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