Search Result

Results for "

Oct-CA(1-7)M(2-9)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Oct3/4 (9) 5-HT Receptor (1) Adrenergic Receptor (3) Antibiotic (2) Apoptosis (1) Autophagy (2) Bacterial (5) Biochemical Assay Reagents (5) Carbonic Anhydrase (1) Dopamine Receptor (4) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (2) Isotope-Labeled Compounds (3) MDM-2/p53 (1) Monoamine Transporter (1) OAT (3) Reactive Oxygen Species (1) Reference Standards (1) Serotonin Transporter (1) TET Protein (1) Tyrosine Hydroxylase (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (2) Endocrinology (2) Infection (7) Inflammation/Immunology (3) Metabolic Disease (8) Neurological Disease (6)

By Targets:

Oct3/4 (9)

5-HT Receptor (1)

Adrenergic Receptor (3)

Antibiotic (2)

Apoptosis (1)

Autophagy (2)

Bacterial (5)

Biochemical Assay Reagents (5)

Carbonic Anhydrase (1)

Dopamine Receptor (4)

Drug Intermediate (1)

Drug Metabolite (1)

Endogenous Metabolite (2)

Isotope-Labeled Compounds (3)

MDM-2/p53 (1)

Monoamine Transporter (1)

OAT (3)

Reactive Oxygen Species (1)

Reference Standards (1)

Serotonin Transporter (1)

TET Protein (1)

Tyrosine Hydroxylase (2)

By Research Areas:

Cancer (6)

Cardiovascular Disease (2)

Endocrinology (2)

Infection (7)

Inflammation/Immunology (3)

Metabolic Disease (8)

Neurological Disease (6)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Oct3/4

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18773

Oct3/4-inducer-1	Oct3/4	Inflammation/Immunology
Oct3/4-inducer-1 (compound 2) is a potent *Oct3/4* inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4, and enhances its transcriptional activity in diverse human somatic cells .

HY-119672

Oct4 inducer-1	Oct3/4	Others
Oct4 inducer-1 (compound OAC-3) is a potent *Oct4* activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .

HY-W010410

Oct-1-en-3-ol	Others	Neurological Disease Metabolic Disease
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling .

HY-P3914

Cecropin A (1-7)-Melittin A (2-9) Oct-CA(1-7)M(2-9)	Bacterial	Infection
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .

HY-107740

Pseudoisocyanine iodide 1,1'-Diethyl-2,2'-cyanine iodide; Decynium 22; Diethylcyanine iodide; Eastman 7851	Monoamine Transporter Serotonin Transporter	Neurological Disease
Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, *OCT2, OCT3) and plasma membrane monoamine transporter (PMAT*). Pseudoisocyanine iodide has antidepressant activity .

HY-W046906

*(E)-Oct-2-enoic acid*	Endogenous Metabolite	Metabolic Disease
(E)-Oct-2-enoic acid is an endogenous metabolite.

HY-154951

Oct4 inducer-2	Oct3/4	Others
Oct4 inducer-2 is an *OCT4* inducer, which can maintain the formation of hiPSCs by promoting the expression of endogenous OCT4, which can be used in anti-aging research .

HY-W010410S

Oct-1-en-3-ol-d3	Isotope-Labeled Compounds	Metabolic Disease
Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-113146

2-Octenal Oct-2-enal	Biochemical Assay Reagents	Others
2-Octenal is an unsaturated aldehyde commonly found in essential oils of various plants, especially citrus fruits. 2-Octenal has unique chemical properties that make it an important ingredient in many applications where a strong, sweet and fruity aroma is desired. It is commonly used as a flavoring agent in food and beverages, and as a fragrance in perfumes, soaps, and cosmetics.

HY-W010410R

Oct-1-en-3-ol (Standard)	Others	Neurological Disease Metabolic Disease
Methyl ricinoleate (Standard) is the analytical standard of Methyl ricinoleate. This product is intended for research and analytical applications. Methyl ricinoleate is a compound belonging to the group of fatty acid methyl esters. It is derived from ricinoleic acid, a monounsaturated omega-9 fatty acid found in castor oil. Methyl ricinoleate is often used as a reference compound for the analysis of fatty acid methyl esters by gas chromatography. It has also been investigated for its potential use as a biofuel and as an ingredient in the production of biodegradable plastics and surfactants.

HY-W575291

*tert-Butyl oct-7-yn-1-ylcarbamate* N-Boc-Oct-7-yn-1-amine	Biochemical Assay Reagents	Others
tert-Butyl oct-7-yn-1-ylcarbamate (N-Boc-oct-7-yn-1-amine) is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.

HY-W134163S

*(E)-Oct-2-enal-d2* trans-2-Octen-1-al-d₂	Isotope-Labeled Compounds	Others
(E)-Oct-2-enal-d₂ is deuterated labeled (E)-Oct-2-enal.

HY-W615153

*Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH*	Drug Intermediate	Metabolic Disease
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the chemical synthesis.

HY-W046907

*Ethyl (E)-oct-2-enoate* trans-2-Octenoic acid ethyl ester	Biochemical Assay Reagents	Others
Ethyl (E)-oct-2-enoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W039379

*Methyl (E)-oct-2-enoate* trans-2-Octenoic acid methyl ester	Biochemical Assay Reagents	Others
Methyl (E)-oct-2-enoate is commonly used as an ingredient in perfume, cologne, and food flavor in the perfume and fragrance industry. Its pleasant fragrance and low volatility make it a good choice for adding fruit to various products. A popular choice for incense, in addition to its application in the fragrance and fragrance industry, Methyl (E)-oct-2-enoate is also used as a raw material for the synthesis of other organic compounds, it can be oxidized to form methyl 3-oxobutyrate, Used in the production of pharmaceuticals and agrochemicals. Overall, Methyl (E)-oct-2-enoate is a versatile compound that is used in various industries for its pleasant aroma and reactivity, its fruity and floral notes in fragrances and essences Industry is highly sought after, and its ability to serve as a starting material for other compounds makes it useful in organic synthesis.

HY-N9071

*5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione*	Others	Others
5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione is a Lignans product that can be isolated from the herbs of Cassia fistula .

HY-12884

OAC2	Oct3/4	Others
OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.

HY-18771

O4I1	Oct3/4	Others
O4I1 is as a potent Oct3/4 inducer.

HY-N0750

Monocrotaline Maximum Cited Publications 33 Publications Verification Crotaline	Others	Metabolic Disease Cancer
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits *OCT-1* and *OCT-2* with IC₅₀s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. ^[2][6][8].

HY-12303

OAC1 1 Publications Verification	Oct3/4 TET Protein	Cancer
OAC1 is a potent *Oct4* activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and TET1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .

HY-W106629

3-Octenoic acid	Biochemical Assay Reagents	Others
Oct-3-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B0193A

Prazosin hydrochloride 10+ Cited Publications	Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders . Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC₅₀ of 0.15 nM .Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC₅₀s of 1.8, and 13 μM, respectively .

HY-B0193AR

Prazosin hydrochloride (Standard)	Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Prazosin (hydrochloride) (Standard) is the analytical standard of Prazosin (hydrochloride). This product is intended for research and analytical applications. Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders . Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC₅₀ of 0.15 nM .Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC₅₀s of 1.8, and 13 μM, respectively .

HY-18772

O4I2	Oct3/4	Others
O4I2 is a potent *Oct3/4* inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1 .

HY-155528

O4I4	Others	Others
O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research .

HY-W046906R

*(E)-Oct-2-enoic acid (Standard)*	Endogenous Metabolite	Metabolic Disease
Timosaponin BII (Standard) is the analytical standard of Timosaponin BII. This product is intended for research and analytical applications. Timosaponin BII (Prototimosaponin A III) is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities .

HY-W781133

cDPCP cis-[Pt(NH3)2(N1-pyridine)Cl]Cl	Others	Cancer
cDPCP (cis-[Pt(NH3)2(N1-pyridine)Cl]Cl) is a DNA crosslinking agent and also a substrate for *OCT1* and *OCT2*. DPCP exhibits anticancer activity and can improve the survival rate of sarcoma-180 mice. cDPCP is suitable for the research of colorectal cancer and cancers with appropriate cation transporters .

HY-100057

BMY 28674 6-Hydroxybuspirone; 6'-Hydroxybuspirone; BMS 528215	5-HT Receptor Drug Metabolite Dopamine Receptor	Neurological Disease
BMY 28674 (6-Hydroxybuspirone) is the active metabolite of the anxiolytic buspirone (HY-B1115A) and is metabolized by CYP3A4.4. BMY 28674 binds to the serotonin (5-HT) receptor subtype 5-HT1A in the rat hippocampus and dorsal raphe (EC₅₀s are 4 and 1 μM, respectively) and is an antagonist of dopamine D2, D3, and D4 receptors (IC₅₀s are 3.1, 4.9, and 0.85 μM, respectively). BMY 28674 also inhibits organic cation transporter 1 (OCT1), OCT2, and OCT3 expressing human transporters in S2 proximal tubule cells in a concentration-dependent manner.

HY-118132

LL-Z1220	Antibiotic	Infection
LL-Z1220 is a novel antibiotic with the structure of 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one. This appears to be the first reported natural product containing a benzene dioxide group. This antibiotic readily undergoes valence isomerization to form 1,4-dioxopentacyclo. The chemical and spectroscopic properties of the antibiotic suggest that the benzene dioxide has a cis configuration.

HY-133825

Cyazofamid IKF-916	Oct3/4 OAT	Infection
Cyazofamid exerts its bactericidal effect by impairing ATP production. Cyazofamid inhibits organic cation transporter 3 (OCT3) and OAT1, with IC₅₀ values of 1.54 and 17.3 μM, respectively .

HY-N2003

D-Tetrahydropalmatine	Dopamine Receptor	Metabolic Disease
D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis . D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors . D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor .

HY-119063

L-645151	Carbonic Anhydrase	Others
L-645151 is a carbonic anhydrase inhibitor with ocular penetration and hypotensive activity. L-645151 lowers the elevated intraocular pressure (IOP) of o-chymotripsinized (o-CT) rabbit eyes. L-645151 is promising for research of an ocular hypotensive agent .

HY-119666

Rooperol	Apoptosis Reactive Oxygen Species MDM-2/p53 Oct3/4	Inflammation/Immunology Cancer
Rooperol is a norlignan analog with antitumor, anti-inflammatory, and antioxidant activities. Rooperol induces apoptosis in CSCs through a mitochondrial-induced increase in ROS and a p53-dependent pathway, while also downregulating the expression of key stem cell regulatory factors, such as *Oct4, Nanog, and Sox2*, ultimately exerting its anticancer effects .

HY-170993

Antimicrobial agent-39	Antibiotic Bacterial	Infection Inflammation/Immunology
Antimicrobial agent-39 (Compound 8i) is an antibiotic that targets 50S ribosomal subunit and inhibits bacterial protein synthesis. Antimicrobial agent-39 disrupts bacterial cell membranes, leads to leakage of cell contents, thereby exhibiting board-spectrum actibacterial activity. Antimicrobial agent-39 targets organic cation transporters (OCTs), accumulates in infected kidneys, thereby ameliorating pyelonephritis in mouse models .

HY-B0306

Prothionamide Protionamide	Bacterial	Infection
Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .

HY-B0306S

Prothionamide-d5 Protionamide-d₅	Isotope-Labeled Compounds Bacterial	Infection
Prothionamide-d₅ is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .

HY-B0306R

Prothionamide (Standard) Protionamide (Standard)	Bacterial	Infection
Prothionamide (Standard) is the analytical standard of Prothionamide (HY-B0306). This product is intended for research and analytical applications. Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .

HY-B0927

Hydrastine (-)-β-Hydrastine; (1R,9S)-β-Hydrastine	Tyrosine Hydroxylase Dopamine Receptor OAT	Neurological Disease
Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage .

HY-103216A

RWJ52353 hydrochloride	Adrenergic Receptor	Neurological Disease
RWJ-52353 hydrochloride is an orally potent, highly selective α2D adrenergic receptor agonist (Ki: 1.5 nM) with potential analgesic effects. RWJ-52353 hydrochloride demonstrated analgesic activity in abdominal tests in rats and mice, and improved agitation in mice in the hot plate test and tail flick test. RWJ-52353 hydrochloride also regulates the organic cation transporter (OCT) subtype, inhibiting rOCT1 and rOCT2 with IC₅₀s of 100 μM and 20 μM respectively; it also activates rOCT3, affecting [3H]-1- in cells. Methyl-4-phenylpyridinium ([3H]MPP) transport .

HY-B0927R

Hydrastine (Standard) (-)-β-Hydrastine (Standard); (1R,9S)-β-Hydrastine (Standard)	Reference Standards Tyrosine Hydroxylase Dopamine Receptor OAT	Others
Hydrastine (Standard) is the analytical standard of Hydrastine (HY-B0927). This product is intended for research and analytical applications. Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage .

Cat. No.	Product Name

HY-L039

Reprogramming Compound Library	2,674 compounds
Techniques for reprogramming somatic cells create new opportunities for drug screening, disease modeling, artificial organ development, and cell therapy. The development of reprogramming techniques has grown exponentially since Yamanaka reprogrammed somatic cells to become induced pluripotent stem cells (iPSCs) using four transcription factors, OCT4, SOX2, KLF4, and c-MYC in 2006. Despite the development of efficient reprogramming methods, most methods are inappropriate for clinical applications because they carry the risk of integrating exogenous genetic factors or use oncogenes. Alternative approaches, such as those based on miRNA, non-viral genes, non-integrative vectors, and small molecules, have been studied as possible solutions to the problems. Among these alternatives, small molecules are attractive options for clinical applications. Reprogramming using small molecules is inexpensive and easy to control in a concentration- and time-dependent manner. It offers a high level of cell permeability, ease of synthesis and standardization, and it is appropriate for mass-producing cells. MCE Reprogramming Compound Library contains a unique collection of 2,674 compounds that act on reprogramming signaling pathways. These compounds are potential stimulators for reprogramming. This library is a useful tool for researching reprogramming and regenerative medicine.

Reprogramming Compound Library

2,674 compounds

Techniques for reprogramming somatic cells create new opportunities for drug screening, disease modeling, artificial organ development, and cell therapy. The development of reprogramming techniques has grown exponentially since Yamanaka reprogrammed somatic cells to become induced pluripotent stem cells (iPSCs) using four transcription factors, OCT4, SOX2, KLF4, and c-MYC in 2006. Despite the development of efficient reprogramming methods, most methods are inappropriate for clinical applications because they carry the risk of integrating exogenous genetic factors or use oncogenes. Alternative approaches, such as those based on miRNA, non-viral genes, non-integrative vectors, and small molecules, have been studied as possible solutions to the problems. Among these alternatives, small molecules are attractive options for clinical applications. Reprogramming using small molecules is inexpensive and easy to control in a concentration- and time-dependent manner. It offers a high level of cell permeability, ease of synthesis and standardization, and it is appropriate for mass-producing cells.

MCE Reprogramming Compound Library contains a unique collection of 2,674 compounds that act on reprogramming signaling pathways. These compounds are potential stimulators for reprogramming. This library is a useful tool for researching reprogramming and regenerative medicine.

Cat. No.	Product Name	Type

HY-W039379

*Methyl (E)-oct-2-enoate* trans-2-Octenoic acid methyl ester	Biochemical Assay Reagents
Methyl (E)-oct-2-enoate is commonly used as an ingredient in perfume, cologne, and food flavor in the perfume and fragrance industry. Its pleasant fragrance and low volatility make it a good choice for adding fruit to various products. A popular choice for incense, in addition to its application in the fragrance and fragrance industry, Methyl (E)-oct-2-enoate is also used as a raw material for the synthesis of other organic compounds, it can be oxidized to form methyl 3-oxobutyrate, Used in the production of pharmaceuticals and agrochemicals. Overall, Methyl (E)-oct-2-enoate is a versatile compound that is used in various industries for its pleasant aroma and reactivity, its fruity and floral notes in fragrances and essences Industry is highly sought after, and its ability to serve as a starting material for other compounds makes it useful in organic synthesis.

Methyl (E)-oct-2-enoate

trans-2-Octenoic acid methyl ester

Biochemical Assay Reagents

Methyl (E)-oct-2-enoate is commonly used as an ingredient in perfume, cologne, and food flavor in the perfume and fragrance industry. Its pleasant fragrance and low volatility make it a good choice for adding fruit to various products. A popular choice for incense, in addition to its application in the fragrance and fragrance industry, Methyl (E)-oct-2-enoate is also used as a raw material for the synthesis of other organic compounds, it can be oxidized to form methyl 3-oxobutyrate, Used in the production of pharmaceuticals and agrochemicals. Overall, Methyl (E)-oct-2-enoate is a versatile compound that is used in various industries for its pleasant aroma and reactivity, its fruity and floral notes in fragrances and essences Industry is highly sought after, and its ability to serve as a starting material for other compounds makes it useful in organic synthesis.

HY-113146

2-Octenal Oct-2-enal	Biochemical Assay Reagents
2-Octenal is an unsaturated aldehyde commonly found in essential oils of various plants, especially citrus fruits. 2-Octenal has unique chemical properties that make it an important ingredient in many applications where a strong, sweet and fruity aroma is desired. It is commonly used as a flavoring agent in food and beverages, and as a fragrance in perfumes, soaps, and cosmetics.

HY-W046907

*Ethyl (E)-oct-2-enoate* trans-2-Octenoic acid ethyl ester	Biochemical Assay Reagents
Ethyl (E)-oct-2-enoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W106629

3-Octenoic acid	Biochemical Assay Reagents
Oct-3-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P3914

Cecropin A (1-7)-Melittin A (2-9) Oct-CA(1-7)M(2-9)	Bacterial	Infection
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010410

Oct-1-en-3-ol	Microorganisms Source classification Plants	Others
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling .

HY-W046906

*(E)-Oct-2-enoic acid*	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(E)-Oct-2-enoic acid is an endogenous metabolite.

HY-N0750

Monocrotaline 30+ Cited Publications Crotaline	Structural Classification Alkaloids Pyrrole Alkaloids Classification of Application Fields Leguminosae Crotalaria pallida Ait. Plants Disease Research Fields Cancer	Others
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits *OCT-1* and *OCT-2* with IC₅₀s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. ^[2][6][8].

HY-N2003

D-Tetrahydropalmatine	Alkaloids Structural Classification Corydalis yanhusuo W. T. Wang Classification of Application Fields Source classification Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields Papaveraceae	Dopamine Receptor
D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis . D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors . D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor .

HY-B0927

Hydrastine (-)-β-Hydrastine; (1R,9S)-β-Hydrastine	Structural Classification Alkaloids Piperidine Alkaloids Classification of Application Fields Ranunculaceae Other Diseases Plants Disease Research Fields	Tyrosine Hydroxylase Dopamine Receptor OAT
Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage .

HY-W010410R

Oct-1-en-3-ol (Standard)	Microorganisms Source classification Plants	Others
Methyl ricinoleate (Standard) is the analytical standard of Methyl ricinoleate. This product is intended for research and analytical applications. Methyl ricinoleate is a compound belonging to the group of fatty acid methyl esters. It is derived from ricinoleic acid, a monounsaturated omega-9 fatty acid found in castor oil. Methyl ricinoleate is often used as a reference compound for the analysis of fatty acid methyl esters by gas chromatography. It has also been investigated for its potential use as a biofuel and as an ingredient in the production of biodegradable plastics and surfactants.

HY-N9071

*5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione*	Cassia fistula L. Structural Classification Leguminosae Source classification Lignans Cassia Phenylpropanoids Plants	Others
5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione is a Lignans product that can be isolated from the herbs of Cassia fistula .

HY-W046906R

*(E)-Oct-2-enoic acid (Standard)*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Timosaponin BII (Standard) is the analytical standard of Timosaponin BII. This product is intended for research and analytical applications. Timosaponin BII (Prototimosaponin A III) is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities .

HY-B0927R

Hydrastine (Standard) (-)-β-Hydrastine (Standard); (1R,9S)-β-Hydrastine (Standard)	Structural Classification Alkaloids Piperidine Alkaloids Ranunculaceae Plants	Reference Standards Tyrosine Hydroxylase Dopamine Receptor OAT
Hydrastine (Standard) is the analytical standard of Hydrastine (HY-B0927). This product is intended for research and analytical applications. Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage .

Species:	Human (2) Mouse (1)
Tag:	His (3) SUMO (1)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P78020

	Endoglycan/PODXL2 Protein, Human (HEK293, His) Endoglycan; PODLX2; brain-1; BRN1; EG; Oct-8; OTF8; UNQ1861/PRO3742	Human	HEK293
	The endocan/PODXL2 protein serves as a ligand for angioselectin, enabling leukocytes to rapidly roll on the vascular surface through high-affinity divalent cation-dependent interactions with E-, P-, and L-selectin. Through disulfide bonds, the protein forms homodimers and interacts with specific selectins, including SELL, SELE, and SELP. Endoglycan/PODXL2 Protein, Human (HEK293, His) is the recombinant human-derived Endoglycan/PODXL2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P72201

	GAPDH Protein, Human (His-SUMO) G3P_HUMAN; G3PD; G3PDH; GAPD; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; glyceraldehyde 3-PDH; Glyceraldehyde-3-phosphate dehydrogenase; HEL-S-162eP; KNC-NDS6; MGC102544; OCAS; p38 component; Oct1 coactivator in S phase; 38-KD component; peptidyl cysteine S nitrosylase GAPDH	Human	E. coli
	GAPDH, a multifunctional protein, acts as a key enzyme in glycolysis, catalyzing the conversion of G3P. It also functions as a nitrosylase, impacting nuclear processes. In addition, it influences cytoskeleton organization, associates with CHP1, participates in transcript-selective translation inhibition, contributes to immune responses, and mediates nuclear events through S-nitrosylation of target proteins. GAPDH Protein, Human (His-SUMO) is the recombinant human-derived GAPDH protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P78021

	Endoglycan/PODXL2 Protein, Mouse (HEK293, His) Endoglycan; PODLX2; brain-1; BRN1; EG; Oct-8; OTF8; UNQ1861/PRO3742	Mouse	HEK293
	Endoglycan/PODXL2 Protein serves as a ligand for vascular selectins, enabling leukocyte rolling on vascular surfaces via high affinity interactions with E-, P-, and L-selectins. It exists as a disulfide-linked homodimer. Furthermore, Endoglycan/PODXL2 Protein interacts with SELL, SELE, and SELP, enhancing its role in leukocyte adhesion and trafficking in the vasculature. Endoglycan/PODXL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Endoglycan/PODXL2 protein, expressed by HEK293 , with C-His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-W010410S

Oct-1-en-3-ol-d3

Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-W134163S

*(E)-Oct-2-enal-d2*
(E)-Oct-2-enal-d₂ is deuterated labeled (E)-Oct-2-enal.

HY-B0306S

Prothionamide-d5

Prothionamide-d₅ is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80440

	Oct-4 Antibody (YA837) MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; Oct3; Oct4; Octamer binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3; OTF 3; OTF 4; OTF	WB, ICC/IF	Human, Mouse
	Oct-4 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 39 kDa, targeting to POU5F1. It can be used for WB,ICC assays with tag free, in the background of Human, Mouse.

HY-P80770

	Oct-4 Antibody MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; Oct3; Oct4; Octamer binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3; OTF 3; OTF 4; OTF	WB, IHC-P, ICC/IF, IP, ChIP	Human, Mouse
	Oct-4 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to POU5F1. It can be used for WB,IHC-P,ICC/IF,IP,ChIP assays with tag free, in the background of Human, Mouse.

HY-P84462

	OCT4 Antibody (YA4159) Oct3; Oct4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; MGC22487; POU5F1	WB, ICC/IF, FC, ELISA	Human

HY-P81782

	Oct-2 Antibody (YA1527) POU2F2; Oct2; OTF2; POU domain; class 2; transcription factor 2; Lymphoid-restricted immunoglobulin Octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2	WB, ICC/IF, IP, FC	Human, Mouse, Rat
	Oct-2 Antibody (YA1527) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1527), with a predicted molecular weight of 51 kDa (observed band size: 58 kDa). Oct-2 Antibody (YA1527) can be used for WB, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P84463

	POU5F1 Antibody (YA4160) Oct3; Oct4; OTF3; OTF4; OTF-3; Oct-3; Oct-4	IHC-P, FC, ELISA	Human

HY-P84168

	POU3F2 Antibody (YA3865) BRN2; Oct7; OTF7; OTF-7; POUF3; brn-2; Oct-7; N-Oct3	WB, ELISA	Human

HY-P83828

	SLC22A1 Antibody (YA3525) Oct1; HOct1; Oct1_cds; SLC22A1	FC, ELISA	Human

HY-P82681

	SLC22A1 Antibody (YA2426) hOct1; Oct1; Slc22a1	WB, FC	Human
	SLC22A1 Antibody (YA2426) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2426), targeting SLC22A1, with a predicted molecular weight of 61 kDa (observed band size: 72 kDa). SLC22A1 Antibody (YA2426) can be used for WB, FC experiment in human background.

HY-P82467

	BOB1 Antibody (YA2212) BOB 1; BOB-1; OBF 1; OBF1; OCA B; OCA-B; OCAB; Oct binding factor 1; Pou2af1	WB, IHC-P, ICC/IF, FC	Human
	BOB1 Antibody (YA2212) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2212), targeting BOB1, with a predicted molecular weight of 27 kDa (observed band size: 35 kDa). BOB1 Antibody (YA2212) can be used for WB, IHC-P, ICC/IF, FC experiment in human background.

HY-P83085

	SLC22A3 Antibody (YA2830) SLC22A3; EMTH; Oct3; Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3	WB, IHC-P, FC	Human
	SLC22A3 Antibody (YA2830) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2830), targeting SLC22A3, with a predicted molecular weight of 61 kDa (observed band size: 75 kDa). SLC22A3 Antibody (YA2830) can be used for WB, IHC-P, FC experiment in human background.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Oct-CA(1-7)M(2-9)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products