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Results for "

OVK18

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-172749
    IMCTA-C14 TFA

    		Autophagy Bacterial Biochemical Assay Reagents Infection Cancer
    IMCTA-C14 TFA, a trehalose analog, is a detergent. IMCTA-C14 TFA shows autophagy-inducing activity in OVK18 cells and can be effectively used in membrane protein research. IMCTA-C14 TFA is active against various bacteria (MICs = 8-128 µg/mL) and is cytotoxic against cancer cell lines (IC50s = 2.9-29.2 µg/mL) .
    IMCTA-C14 TFA
  • HY-179210
    ATX020

    		Kinesin Cancer
    ATX020 is a potent, selective and orally active kinesin KIF18A inhibitor. ATX020 inhibits the ATPase activity of KIF18A in humans, rats and dogs, with IC50 values of 0.11 μM, 0.16 μM and 0.24 μM, respectively. ATX020 shows high selectivity for other motor proteins (CENP-E, Eg5, KIF15, etc.), with IC50 values >10 μM and only has a weak inhibitory effect on KIF19 (IC50 = 6.1 μM). ATX020 can inhibit cancer cells proliferation .
    ATX020

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