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LSD1-IN-43

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176254
    LSD1-IN-43

    		Histone Demethylase Amyloid-β Neurological Disease
    LSD1-IN-43 is a highly selective, reversible, orally active and brain-penetrant LSD1 inhibitor with an IC50 value of 0.8 μM. LSD1-IN-43 has low inhibitory activity against MAO-A and MAO-B, two homologs of LSD1. LSD1-IN-43 significantly inhibits Aβ aggregation and enhances Aβ-induced neuronal cell viability. LSD1-IN-43 can be used for the study of Alzheimer’s disease (AD)[1].
    LSD1-IN-43

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