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Results for "

Kininase II

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Peptides

4

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2983
    Angiotensin-converting enzyme

    Kininase II; CD143

    		 Endogenous Metabolite Cardiovascular Disease Cancer
    Angiotensin-converting enzyme (Kininase II) is a dicarboxypeptidase, it converts inactive Angiotensin I (Ang I) to active Ang II and degrades active bradykinin (BK). Angiotensin-converting enzyme is a potent vasoconstrictor, is often used in biochemical studies .
    Angiotensin-converting enzyme
  • HY-103294
    R892

    		Endogenous Metabolite Others
    R892 is a selective and efficient bradyKinin B1 receptor antagonist with significant antagonistic activity. The pA2 values of R892 in human and rabbit B1 receptors are 8.8 and 8.6 respectively, indicating its strong anti-activity at these receptors. R892 exhibits selectivity with ID50 values of 2.8 nM and >600 nM for B1 and B2 receptors, respectively, and has no endogenous agonist activity. R892 is resistant to aminopeptidase and kininase II (ACE) degradation and exhibits metabolic stability .
    R892

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