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Results for "

GluR2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	iGluR (4) mGluR (1) PKC (2) Small Interfering RNA (siRNA) (4)
By Research Areas:	Neurological Disease (7)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Peptides

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1399A

Pep2m, myristoylated TFA Myr-Pep2m TFA	PKC	Neurological Disease
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, *N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions*. PKMζ is an autonomously active isozyme of protein kinase C (PKC) ^[2].

HY-13456

LY-404187	iGluR	Neurological Disease
LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors, with the EC₅₀s of 5.65, 0.15, 1.44, 1.66 and 0.21 µM for *GluR1i, GluR2i, GluR2o, GluR3i* and *GluR4i*, respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases ^[2].

HY-P1055

Pep2-SVKE	iGluR	Neurological Disease
Pep2-SVKE is an inactive control peptide for pep2-SVKI (HY-P1056). Pep2-SVKE is an inhibitory peptide corresponding to the last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Pep2-SVKE does not block AMPA-mediated [ ³H]DA exocytosis. Pep2-SVKE does not bind to GRIP or PICK43 and does not block retention of PICK1 by GST-GluR2 and LTD ^{[1] [2] [3] [4] [5]}.

HY-P1399

Pep2m, myristoylated Myr-Pep2m	PKC	Neurological Disease
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, *N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions*. PKMζ is an autonomously active isozyme of protein kinase C (PKC) ^[2].

HY-100840

(S)-4C3HPG (S)-4-Carboxy-3-hydroxyphenylglycine	mGluR	Neurological Disease
(S)-4C3HPG ((S)-4-Carboxy-3-hydroxyphenylglycine) is an antagonist of metabotropic glutamate receptor 1a (mGluR 1a) and an agonist of *GluR2. (S)-4C3HPG has the anticonvulsant activity and protects against audiogenic seizures in DBA*/2 mice .

HY-P1059

Pep2-AVKI	iGluR	Neurological Disease
Pep2-AVKI is a selective peptide inhibitor of the binding of the AMPA receptor subunit (GluR2) at the C-terminal PDZ site to C-kinase (PICK1). Pep2-AVKI does not affect the binding of (AMPA-type glutamate receptor) GluA2 to GRIP or ABP. Pep2-AVKI does not increase the amplitude of AMPA currents. pep2-AVKI can be used to study neurological diseases ^[2] .

HY-P1057

Pep4c	iGluR	Neurological Disease
Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity ^{[1] [2] [3] [4] [5] [6]}.

HY-RS21589

Gria2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gria2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gria2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gria2 Mouse Pre-designed siRNA Set A Gria2 Mouse Pre-designed siRNA Set A

HY-RS05792

GRIA2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GRIA2 Human Pre-designed siRNA Set A contains three designed siRNAs for GRIA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GRIA2 Human Pre-designed siRNA Set A GRIA2 Human Pre-designed siRNA Set A

HY-RS05822

GRM2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GRM2 Human Pre-designed siRNA Set A contains three designed siRNAs for GRM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GRM2 Human Pre-designed siRNA Set A GRM2 Human Pre-designed siRNA Set A

HY-RS28107

Gria2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gria2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gria2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gria2 Rat Pre-designed siRNA Set A Gria2 Rat Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P1399A

Pep2m, myristoylated TFA Myr-Pep2m TFA	PKC	Neurological Disease
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, *N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions*. PKMζ is an autonomously active isozyme of protein kinase C (PKC) ^[2].

HY-P1055

Pep2-SVKE	iGluR	Neurological Disease
Pep2-SVKE is an inactive control peptide for pep2-SVKI (HY-P1056). Pep2-SVKE is an inhibitory peptide corresponding to the last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Pep2-SVKE does not block AMPA-mediated [ ³H]DA exocytosis. Pep2-SVKE does not bind to GRIP or PICK43 and does not block retention of PICK1 by GST-GluR2 and LTD ^{[1] [2] [3] [4] [5]}.

HY-P1399

Pep2m, myristoylated Myr-Pep2m	PKC	Neurological Disease
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, *N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions*. PKMζ is an autonomously active isozyme of protein kinase C (PKC) ^[2].

HY-P1059

Pep2-AVKI	iGluR	Neurological Disease
Pep2-AVKI is a selective peptide inhibitor of the binding of the AMPA receptor subunit (GluR2) at the C-terminal PDZ site to C-kinase (PICK1). Pep2-AVKI does not affect the binding of (AMPA-type glutamate receptor) GluA2 to GRIP or ABP. Pep2-AVKI does not increase the amplitude of AMPA currents. pep2-AVKI can be used to study neurological diseases ^[2] .

HY-P1057

Pep4c	iGluR	Neurological Disease
Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity ^{[1] [2] [3] [4] [5] [6]}.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81398

	Ionotropic Glutamate Receptor 2 Antibody (YA1143) GRIA2; GluR2; Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic; AMPA 2; GluA2	IHC-P	Human
	Ionotropic Glutamate Receptor 2 Antibody (YA1143) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ionotropic Glutamate Receptor 2.

HY-P84316

	Ionotropic Glutamate Receptor 2 Antibody (YA4013) GluA2; GluR2; GluR-B; GluR-K2	WB, FC, ELISA	Human
	Ionotropic Glutamate Receptor 2 Antibody (YA4013) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ionotropic Glutamate Receptor 2.

HY-P84569

	Metabotropic Glutamate Receptor 2 Antibody (YA4266) GluR2; mGlu2; GPRC1B; MGluR2	WB, FC, ELISA	Human
	Metabotropic Glutamate Receptor 2 Antibody (YA4266) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Metabotropic Glutamate Receptor 2.

HY-P84317

	Ionotropic Glutamate Receptor 2 Antibody (YA4014) GluR2; GluRB; GluA2; HBGR2; GluR-K2	IHC-P, FC, ELISA	Human
	Ionotropic Glutamate Receptor 2 Antibody (YA4014) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Ionotropic Glutamate Receptor 2.

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Gria2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Gria2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gria2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

GRIA2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
GRIA2 Human Pre-designed siRNA Set A contains three designed siRNAs for GRIA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GRM2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
GRM2 Human Pre-designed siRNA Set A contains three designed siRNAs for GRM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gria2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Gria2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gria2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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