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Results for "

GluA2

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

7

Peptides

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2259
    TAT-GluA2 3Y
    1 Publications Verification

    iGluR Neurological Disease
    TAT-GluA2 3Y, an interference peptide, blocks long-term depression (LTD) at glutamatergic synapses by disrupting the endocytosis of AMPAR. TAT-GluA2 3Y can alleviate Pentobarbital-induced spatial memory deficits and synaptic depression [2] .
    TAT-GluA2 3Y
  • HY-12508

    iGluR Neurological Disease
    CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor.
    CMPDA
  • HY-161665

    iGluR Neurological Disease
    BDZ-P7 inhibits AMPA receptor GluA2, GluA1/2, GluA2/3, and GluA1 subunit with IC50s of 3.03 μM, 3.14 μM, 3.19 μM, 3.2 μM. BDZ-P7 has neuroprotective effect and reinstates locomotor abilities in a mouse model of Parkinson’s disease .
    BDZ-P7
  • HY-P3355

    iGluR Neurological Disease
    p-fin4 is a peptide inhibitor of STEP Phosphatase-GluA2 AMPA receptor interaction with a Ki of 0.4 μM. p-fin4 restores the memory deficits and displays anxiolytic and antidepressant effects in a scopolamine-treated rat model. p-fin4 is a promising lead compound for novel cognitive enhancers and/or behavioral modulators .
    p-fin4
  • HY-P1057

    iGluR Neurological Disease
    Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity [1] [2] [3] [4] [5] [6].
    Pep4c
  • HY-P3354

    iGluR Neurological Disease
    p3Ysh-3 is a peptide inhibitor of STEP Phosphatase-GluA2 AMPA receptor interaction with a Ki of 1.09 μM. p3Ysh-3 restores the memory deficits and displays anxiolytic and antidepressant effects in a scopolamine-treated rat model. p3Ysh-3 is a promising lead compound for novel cognitive enhancers and/or behavioral modulators .
    p3Ysh-3
  • HY-P1058

    iGluR Neurological Disease
    Pep2m is a peptide receptor inhibitor. Pep2m inhibits the interaction between the C-terminus of the AMPA-type glutamate receptor (GluA2) subunit and N-ethylmaleimide-sensitive fusion protein (NSF). Pep2m prevents synaptic long-term depression (LTD). Pep2m can reduce postsynaptic currents in neurons, AMPA-mediated currents in cultured hippocampal neurons, and AMPA receptor surface expression [1] [2] [3] [4] [5].
    Pep2m
  • HY-P1059

    iGluR Neurological Disease
    Pep2-AVKI is a selective peptide inhibitor of the binding of the AMPA receptor subunit (GluR2) at the C-terminal PDZ site to C-kinase (PICK1). Pep2-AVKI does not affect the binding of (AMPA-type glutamate receptor) GluA2 to GRIP or ABP. Pep2-AVKI does not increase the amplitude of AMPA currents. pep2-AVKI can be used to study neurological diseases [2] .
    Pep2-AVKI
  • HY-P1056

    iGluR Neurological Disease
    pep2-SVKI is a selective peptide inhibitor. pep2-SVKI inhibits the binding of AMPA-type glutamate receptor (GluA2) (C-terminal PDZ site) to glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP), and C-kinase interacting protein (PICK1). pep2-SVKI increases the amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD). pep2-SVKI can be used to study neurological diseases [2] .
    pep2-SVKI
  • HY-RS28107

    Small Interfering RNA (siRNA) Others
    Gria2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gria2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Gria2 Rat Pre-designed siRNA Set A
    Gria2 Rat Pre-designed siRNA Set A
  • HY-RS21589

    Small Interfering RNA (siRNA) Others

    Gria2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gria2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gria2 Mouse Pre-designed siRNA Set A
    Gria2 Mouse Pre-designed siRNA Set A
  • HY-RS05792

    Small Interfering RNA (siRNA) Others

    GRIA2 Human Pre-designed siRNA Set A contains three designed siRNAs for GRIA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GRIA2 Human Pre-designed siRNA Set A
    GRIA2 Human Pre-designed siRNA Set A

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