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Isoforms Recommended: GlyT1
Results for "

GLT-1

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Inhibitory Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12741
    LDN-212320
    5+ Cited Publications

    LDN-0212320; OSU-0212320

    		 EAAT Neurological Disease
    LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC [1]
    LDN-212320
  • HY-100784
    Dihydrokainic acid
    1 Publications Verification

    		 EAAT Neurological Disease
    Dihydrokainic acid is a glutamate transporters (especially GLT1) inhibitor. Dihydrokainic acid targets GLT1 with high affinity, effectively inhibiting its transport function. Dihydrokainic acid exerts its effect by inhibiting the uptake of glutamate, leading to an increase in extracellular glutamate concentration, thereby affecting neuronal excitability and neurotransmission. Dihydrokainic acid is mainly applied in the field of neuroscience for research on glutamate-related neural functions, epilepsy, learning, and memory [1] .
    Dihydrokainic acid
  • HY-124619
    GPI-1046

    		EAAT HIV Neurological Disease
    GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity [1] .
    GPI-1046
  • HY-107498
    GNE-8324

    		iGluR Neurological Disease
    GNE-8324 is a selective GluN2A positive allosteric modulator. GNE-8324 selectively enhances NMDA receptor (NMDAR)-mediated synaptic responses in inhibitory but not excitatory neurons [1].
    GNE-8324
  • HY-RS05504
    GLT1D1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GLT1D1 Human Pre-designed siRNA Set A contains three designed siRNAs for GLT1D1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GLT1D1 Human Pre-designed siRNA Set A
    GLT1D1 Human Pre-designed siRNA Set A
  • HY-P990253
    Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5)

    		Notch EAAT Inflammation/Immunology
    Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) is an anti-mouse Delta-like protein 1/DLL1 IgG monoclonal antibody. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) can reverse the inhibition of Treg cells. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) can inhibit the upregulation of GLT-1 expression induced by endothelial cells. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) reduces autoimmune response by reducing B cell activation. Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) can be used for research on inflammation conditions such as lupus nephritis [1] .
    Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5)
  • HY-111093
    Protein kinase inhibitor 8

    		CaMK Neurological Disease
    Protein kinase inhibitor 8 (Compound CK59) is a calmodulin-dependent protein kinase II (CaMKII) inhibitor. By inhibiting the activity of CaMKII, Protein kinase inhibitor 8 can attenuate the cytotoxicity induced by perfluorooctane sulfonic acid (PFOS) and alleviate the downregulation of GLT-1 expression caused by PFOS, thereby reducing neuronal damage. Protein kinase inhibitor 8 may be useful in research related to neurodegenerative diseases [1] .
    Protein kinase inhibitor 8
  • HY-100784R
    Dihydrokainic acid (Standard)

    		Reference Standards EAAT Neurological Disease
    Dihydrokainic acid (Standard) is the analytical standard of Dihydrokainic acid. This product is intended for research and analytical applications. Dihydrokainic acid (DHK) is a glutamate transporter GLT1 (EAAT2) inhibitor. Dihydrokainic acid impairs novel object recognition (NOR) memory performance in mice. Dihydrokainic acid also shows epileptogenic effects [1].
    Dihydrokainic acid (Standard)
  • HY-RS13052
    Slc1a2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Slc1a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc1a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Slc1a2 Mouse Pre-designed siRNA Set A
    Slc1a2 Mouse Pre-designed siRNA Set A
  • HY-RS13051
    SLC1A2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SLC1A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC1A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SLC1A2 Human Pre-designed siRNA Set A
    SLC1A2 Human Pre-designed siRNA Set A
  • HY-RS13053
    Slc1a2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Slc1a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc1a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Slc1a2 Rat Pre-designed siRNA Set A
    Slc1a2 Rat Pre-designed siRNA Set A

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