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Results for "

Ferroptosis inducer-2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161601
    Ferroptosis inducer-2

    		Ferroptosis Reactive Oxygen Species (ROS) Cancer
    Ferroptosis inducer-2 (Compound 24) is an inducer for heme oxygenase-1 (HO-1). Ferroptosis inducer-2 exhibits anticancer activity against triple-negative breast cancer (TNBC) cells through induction of ferroptosis .
    Ferroptosis inducer-2
  • HY-N0115
    Gastrodin
    15+ Cited Publications

    Gastrodine

    		 Apoptosis Ferroptosis Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
    Gastrodin
  • HY-N0696
    Sipeimine
    2 Publications Verification

    Imperialine

    		 PI3K NF-κB Akt NOD-like Receptor (NLR) Pyroptosis Ferroptosis Inflammation/Immunology
    Sipeimine (Imperialine) is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65. Sipeimine inhibits PI3K/AKT phosphorylation, blocks NF-κB nuclear translocation and NLRP3 inflammasome activation. Sipeimine exerts anti-inflammatory activities, inhibits pyroptosis and ferroptosis, and protects the extracellular matrix. Sipeimine can reduce cartilage degradation and synovial inflammation in osteoarthritis and improve PM2.5-induced lung injury. Sipeimine is mainly used in the study of anti-inflammatory and degenerative diseases .
    Sipeimine
  • HY-159940
    Ferroptosis/apoptosis inducer-2

    		Drug Derivative Cancer
    Ferroptosis/apoptosis inducer-2 (compound D2) is an anticancer agent and shows anticancer activity both in vivo and in vitro .
    Ferroptosis/apoptosis inducer-2
  • HY-N0696R
    Sipeimine (Standard)

    Imperialine (Standard)

    		 Reference Standards PI3K NF-κB Akt NOD-like Receptor (NLR) Pyroptosis Ferroptosis Inflammation/Immunology
    Sipeimine (Standard) is the analytical standard of Sipeimine (HY-N0696R). Sipeimine (Imperialine) is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65. Sipeimine inhibits PI3K/AKT phosphorylation, blocks NF-κB nuclear translocation and NLRP3 inflammasome activation. Sipeimine exerts anti-inflammatory activities, inhibits pyroptosis and ferroptosis, and protects the extracellular matrix. Sipeimine can reduce cartilage degradation and synovial inflammation in osteoarthritis and improve PM2.5-induced lung injury. Sipeimine is mainly used in the study of anti-inflammatory and degenerative diseases .
    Sipeimine (Standard)

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