Search Result
Results for "
FISH
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P2959
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FISH oil from menhaden, crude source of omega-3 fatty acids
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Biochemical Assay Reagents
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Others
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Menhaden oil, crude source of omega-3 fatty acids is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-P990302
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nAChR
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Others
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Anti-Human/Rat/Fish AChR Antibody (Mab35) is a rat-derived IgG1 type antibody inhibitor, targeting to human/rat/Fish AChR.
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- HY-D2000
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Fluorescent Dye
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Others
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ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm) .
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- HY-131008
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Fluorescent Dye
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Others
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Fluorescein tyramide is a green fluorescent reagent (λabs: 494 nm; λem: 517 nm). Fluorescein tyramide is widely used for tyramide signal amplification (TSA) with a low-abundance in IHC, ICC, in situ hybridization (FISH) and flow cytometry (FCM) applications .
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- HY-N7113
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Others
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Cancer
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Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities .
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- HY-145533
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KDN
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Endogenous Metabolite
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Others
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3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid protects the oligo/(poly)sialyl chains from exosialidases at nonreducing terminal, and plays a role in egg activation of salmonid fish . 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is abundant in fetal cord red blood cells and malignant human ovarian cancer cells .
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- HY-B1278B
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(±)-Vitamin E acetate
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Biochemical Assay Reagents
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Infection
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(±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .
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- HY-P3957
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Urotensin Receptor
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Others
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Urotensin II, teleost fish is a cyclic peptide. It can be isolated from the caudal neurosecretory system of teleost fish .
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- HY-W011777S
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MS-222-d5
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Isotope-Labeled Compounds
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Neurological Disease
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Tricaine-d5 (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish .
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- HY-N7113R
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Others
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Cancer
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Squalane (Standard) is the analytical standard of Squalane. This product is intended for research and analytical applications. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities .
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- HY-B1278BR
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Biochemical Assay Reagents
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Infection
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(±)-α-Tocopherol acetate (Standard) is the analytical standard of (±)-α-Tocopherol acetate. This product is intended for research and analytical applications. (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .
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- HY-157695
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C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC
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Endogenous Metabolite
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Others
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1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.
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- HY-N6987
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- HY-A0058
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Retinyl β-D-glucoside
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Drug Metabolite
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Metabolic Disease
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Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.
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- HY-W011777
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- HY-N0610
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- HY-W144308R
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Drug Metabolite
Reactive Oxygen Species
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Others
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Glycerol Monoleate (Standard) is the analytical standard of Glycerol Monoleate. This product is intended for research and analytical applications. Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro .
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- HY-W144308
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TCHQ; Tetrachloroquinol
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Drug Metabolite
Reactive Oxygen Species
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Others
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Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol. Tetrachlorohydroquinone increases DNA lesions and induce oxidative stress in rodents .
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- HY-B2167
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- HY-116117
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SOD
Glutathione Peroxidase
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Others
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Salicylcurcumin is a synthetic curcumin analogue with antioxidant activity. Salicylcurcumin may affect lipid peroxidation in fish, favoring increased survival, disease resistance, and ultimately growth rate .
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- HY-W923496
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SFE 24:5; all-cis-4,7,10,13,16-DPA Ethyl ester
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Drug Derivative
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Others
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all-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester (SFE 24:5) is a derivative of Docosapentaenoic acid (DPA). DPA is a fatty acid found in fish oils .
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- HY-115584B
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Parasite
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Infection
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Lufenuron, (-)- is an active isomer form of Lufenuron. Lufenuron is a lipophilic benzoyl urea insecticide and chitin synthesis inhibitor that can be used for flea and fish lice control. Lufenuron inhibits the molting of arthropods .
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- HY-119779
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S 1812
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Insecticide
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Others
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Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .
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- HY-P4432
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GnRH Receptor
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Endocrinology
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(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish .
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- HY-B2167S
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DHA-d5; Cervonic acid-d5
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Endogenous Metabolite
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Neurological Disease
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Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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- HY-B2167S2
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- HY-115584S
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Isotope-Labeled Compounds
Parasite
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Infection
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Lufenuron- 13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods[1][2].
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- HY-115584R
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Parasite
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Infection
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Lufenuron (Standard) is the analytical standard of Lufenuron. This product is intended for research and analytical applications. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods .
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- HY-W011777R
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Biochemical Assay Reagents
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Neurological Disease
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Tricaine (methanesulfonate) (Standard) is the analytical standard of Tricaine (methanesulfonate). This product is intended for research and analytical applications. Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures .
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- HY-N0610R
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Bacterial
Endogenous Metabolite
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Infection
Cancer
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trans-Cinnamic acid (Standard) is the analytical standard of trans-Cinnamic acid. This product is intended for research and analytical applications. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 .
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- HY-113414
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Endogenous Metabolite
Mineralocorticoid Receptor
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Others
Inflammation/Immunology
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Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC50 of 0.16 nM . Deoxycorticosterone could acts as an immune stimulator in fish .
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- HY-N0610S1
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trans-3-Phenylacrylic acid-d7
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Bacterial
Endogenous Metabolite
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Infection
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trans-Cinnamic acid-d7 is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].
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- HY-N0610S
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trans-3-Phenylacrylic acid-d5
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Bacterial
Endogenous Metabolite
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Infection
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trans-Cinnamic acid-d5 is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].
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- HY-W015370R
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Endogenous Metabolite
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Others
Inflammation/Immunology
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Squalane (Standard) is the analytical standard of Squalane. This product is intended for research and analytical applications. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities .
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- HY-N7113S
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Isotope-Labeled Compounds
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Cancer
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Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].
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- HY-W714225
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Monosodium methylarsonate
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Herbicide
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Others
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Sodium methylarsonate (Monosodium methylarsonate) is an organoarsenic compound with environmental toxicity that can be used as a herbicide to control weeds. Sodium methylarsonate interferes with plant metabolic processes, particularly by hindering photosynthesis and protein synthesis, ultimately leading to plant death. Additionally, sodium methylarsonate can induce the production of metallothioneins (MTs) in fish .
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- HY-B1567
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SD 2774; ENT 23393; Alugan
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Insecticide
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Others
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Bromocyclen is a pesticide found in the muscle tissue of rainbow trout from Danish fisheries and in three species of fish (grill, crucian carp and pike) from the River Stell in northern Germany. High concentrations were detected ranging from 0.09 to 1.23 mg/kg fat .
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- HY-115584
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Parasite
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Infection
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Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses .
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- HY-150734A
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Toll-like Receptor (TLR)
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Infection
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ODN 2007 sodium, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 sodium can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .
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- HY-150734
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Toll-like Receptor (TLR)
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Infection
Inflammation/Immunology
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ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .
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- HY-120407
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ENT-33266
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Insecticide
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Others
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Looplure (ENT-33266) is an insect attractant with acute toxicity studies in different animal models showing activity at oral and dermal median lethal doses (LD50) and median lethal concentrations (LC50) for fish with some values, and low toxicity in most cases except for some cases.
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- HY-113000
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Endogenous Metabolite
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Cardiovascular Disease
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Cetoleic acid is a long-chain monounsaturated fatty acid found in deep-sea fish. Cetoleic acid can promote the synthesis of ALA in human HepG2 cells and EPA in vitro in salmon liver cells, affecting cholesterol levels in rodents. Cetoleic acid has potential applications in cardiovascular disease research .
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- HY-119779R
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Insecticide
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Others
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Pyridalyl (Standard) is the analytical standard of Pyridalyl. This product is intended for research and analytical applications. Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .
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- HY-P2962
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TG
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Biochemical Assay Reagents
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Infection
Inflammation/Immunology
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Transglutaminase, Streptoverticillium mobaraense (TG) is an enzyme that forms cross-links between protein molecules. Transglutaminase, Streptoverticillium mobaraense attaches proteins and peptides to small molecules, polymers, surfaces, DNA and other proteins. Transglutaminase, Streptoverticillium mobaraense is widely used in food applications in the meat, fish, dairy and baking industries .
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- HY-D2012
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Fluorescent Dye
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Others
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ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
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- HY-B0816
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Insecticide
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Others
Cancer
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Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
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- HY-P10411
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Bacterial
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Infection
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BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
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- HY-P1287
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iGluR
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Neurological Disease
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Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa .
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- HY-P1525
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MCH (salmon)
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MCHR1 (GPR24)
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Endocrinology
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Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.
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- HY-P1542
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Catostomus urotensin I
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CRFR
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Cardiovascular Disease
Endocrinology
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Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively .
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- HY-147335
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Endogenous Metabolite
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Cardiovascular Disease
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6,9,12,15-Hexadecatetraenoic acid-ethyl ester is an orally active n-1PUFA. 6,9,12,15-Hexadecatetraenoic acid-ethyl ester intake can reduce plasma triglyceride content in mice .
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- HY-P1542B
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Catostomus urotensin I TFA
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CRFR
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Cardiovascular Disease
Endocrinology
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Urotensin I (Catostomus urotensin I) TFA, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively .
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- HY-B1567R
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Insecticide
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Others
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Bromocyclen (Standard) is the analytical standard of Bromocyclen. This product is intended for research and analytical applications. Bromocyclen is a pesticide found in the muscle tissue of rainbow trout from Danish fisheries and in three species of fish (grill, crucian carp and pike) from the River Stell in northern Germany. High concentrations were detected ranging from 0.09 to 1.23 mg/kg fat .
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- HY-W1006349
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1,2,3,4,6,7,8-HpCDF
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Drug Metabolite
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Others
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1,2,3,4,6,7,8-Heptachlorodibenzofuran (1,2,3,4,6,7,8-HpCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,4,6,7,8-Heptachlorodibenzofuran has been found in the soil near municipal waste incinerators, in freshwater fish, and in human breastmilk .
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- HY-P1525A
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MCH (salmon) (TFA)
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MCHR1 (GPR24)
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Endocrinology
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Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.
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- HY-165052
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1,3-Didocosahexaenoin-2-palmitin; DPD; TG(22:6/16:0/22:6)
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Others
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Others
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1,3-Didocosahexaenoyl-2-palmitoyl glycerol (1,3-Didocosahexaenoin-2-palmitin) is a compound that is being studied as a triglyceride positional isomer in fish and marine mammals. The fatty acid binding position of 1,3-Didocosahexaenoyl-2-palmitoyl glycerol varies in different organisms, which may be related to the substrate preference of related enzymes.
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- HY-150145A
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Fluorescent Dye
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Others
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Cy5-UTP sodium (10mM in Water) is a cyanine5-labeled UTP analogue that can produce fluorescent probes in vitro transcription reactions with excitation/emission wavelengths of 650/665 nm. Cy5-UTP sodium can be used in FISH, polychromatic fluorescence analysis, especially the two-color expression array combined with Cy5-UTP .
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- HY-D0193
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Acid Red 18; New Coccine
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Fluorescent Dye
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Others
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Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids .
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- HY-B0816R
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Insecticide
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Others
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Etofenprox (Standard) is the analytical standard of Etofenprox. This product is intended for research and analytical applications. Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
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- HY-B0507
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Antibiotic
Bacterial
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Endocrinology
Cancer
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Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .
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- HY-P5697
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Bacterial
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Infection
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Tilapia piscidin 3 is an antimicrobial peptide with antibacterial activity against gram-positive and -negative bacteria (MIC: 2.44, 2.44, 9.78, 19.55, 0.61 μg/mL for V. vulnificus 204, V. alginolyticus, S. agalactiae 819, E. faecalis BCRC 10066, S. agalactiae BCRC 10787). Tilapia piscidin 3 has hemolytic activity in fish red blood cells .
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- HY-119983
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DBC
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Cytochrome P450
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Cancer
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7H-Dibenzo[c,g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c,g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c,g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites .
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![7H-Dibenzo[c,g]carbazole](//file.medchemexpress.eu/product_pic/hy-119983.gif)
- HY-133823
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C16:1 (cis-11/trans-11) Fatty acid
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Endogenous Metabolite
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Metabolic Disease
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11-Hexadecenoic acid is a monounsaturated fatty acid. 11-cis-Hexadecenoic acid and 11-trans-hexadecenoic acid have been found in ewe milk fat, and levels of each increase with dietary lipid supplementation of linseed, sunflower, olive, or fish oils. 11-trans-Hexadecenoic acid has also been found in intramuscular fat samples isolated from male and female foals. This product is a mixture of 11-cis- and 11-trans-hexadecenoic acids.
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- HY-Y1683
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Racementhol
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GABA Receptor
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Neurological Disease
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DL-Menthol (Racementhol) is an orally active, GABAaR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABAAR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production .
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- HY-B0507S
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Isotope-Labeled Compounds
Antibiotic
Bacterial
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Endocrinology
Cancer
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Sulfathiazole-d4 is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .
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- HY-B0507R
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Antibiotic
Bacterial
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Endocrinology
Cancer
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Sulfathiazole (Standard) is the analytical standard of Sulfathiazole (HY-B0507). This product is intended for research and analytical applications. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .
|
-
- HY-B0507A
-
|
|
Antibiotic
Bacterial
|
Endocrinology
Cancer
|
|
Sulfathiazole sodium is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole sodium increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish. Sulfathiazole sodium is also a cathodic corrosion inhibitor. It inhibits the corrosion of copper by chloride ions through chemical and physical adsorption on the copper surface, reduces the corrosion current density and shifts the corrosion potential negatively .
|
-
- HY-B0507B
-
|
|
Antibiotic
Bacterial
|
Endocrinology
Cancer
|
|
Sulfathiazole (100 μg/mL in acetonitrile) is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole (100 μg/mL in acetonitrile) increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish. Sulfathiazole (100 μg/mL in acetonitrile) is also a cathodic corrosion inhibitor. Sulfathiazole (100 μg/mL in acetonitrile) inhibits the corrosion of copper by chloride ions through chemical and physical adsorption on the copper surface, reduces the corrosion current density and shifts the corrosion potential negatively .
|
-
- HY-N7833
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.
|
-
- HY-121143
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
Bis-Q is an acetylcholine (ACh) agonist that targets voltage-clamped muscle fibers of the fish Xenomystus nigris. Bis-Q exists in two forms: cis-Bis-Q (non-agonist) and trans-Bis-Q (agonist). Photoisomerization converts cis-Bis-Q to trans-Bis-Q, which induces agonist-induced currents. Channels activated by trans-Bis-Q and ACh have similar conductances and open times. Flashes increase the ratio of trans-Bis-Q to cis-Bis-Q until light equilibrium is reached. Further flashes transiently increase agonist-induced currents, indicating binding of trans-Bis-Q to desensitized receptors. Higher concentrations of cis-Bis-Q produce larger agonist-induced currents that decay exponentially. .
|
-
- HY-B0507AR
-
|
|
Antibiotic
Bacterial
|
Endocrinology
Cancer
|
|
Sulfathiazole sodium (Standard) is the analytical standard of Berberine sodium (HY-B0507A). This product is intended for research and analytical applications. Sulfathiazole sodium is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole sodium increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish. Sulfathiazole sodium is also a cathodic corrosion inhibitor. Sulfathiazole sodium inhibits the corrosion of copper by chloride ions through chemical and physical adsorption on the copper surface, reduces the corrosion current density and shifts the corrosion potential negatively .
|
-
- HY-N7864
-
|
all-cis-4,7,10,13,16-Docosapentaenoic acid
|
Biochemical Assay Reagents
|
Others
|
|
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.
|
-
- HY-W014566
-
|
3-(Trifluoromethyl)-4-Nitrophenol; TFM
|
Insecticide
Cytochrome P450
|
Infection
|
|
4-Nitro-3-(trifluoromethyl)phenol (TFM) is a piscicide that is toxic to lampreys (P. marinus) (LC50 values ??are 1.97-2.11 for cysts, 2.05-2.21 for fry, 1.6-2.45 for juveniles, and 1.6-1.63 for adults, respectively). 4-Nitro-3-(trifluoromethyl)phenol is also toxic to juvenile lake sturgeons (A. fulvescens) less than 100 mm, but is nontoxic to a variety of other fish species. 4-Nitro-3-(trifluoromethyl)phenol (50 μM) dissociates oxidative phosphorylation by 22% and 28% in isolated livers of lampreys and rainbow trout (O. mykiss), respectively. 4-Nitro-3-(trifluoromethyl)phenol can be used to control lamprey larval populations.
|
-
- HY-W130878
-
|
|
Complement System
Toll-like Receptor (TLR)
NF-κB
|
Inflammation/Immunology
|
|
4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway .
|
-
- HY-B2167R
-
|
|
Endogenous Metabolite
|
Neurological Disease
Cancer
|
|
Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid .
In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2000
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm) .
|
-
- HY-D0193
-
|
Acid Red 18; New Coccine
|
Dyes
|
|
Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids .
|
-
- HY-D2012
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
|
| Cat. No. |
Product Name |
Type |
-
- HY-P2959
-
|
FISH oil from menhaden, crude source of omega-3 fatty acids
|
Cell Assay Reagents
|
|
Menhaden oil, crude source of omega-3 fatty acids is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B1278B
-
|
(±)-Vitamin E acetate
|
Biochemical Assay Reagents
|
|
(±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .
|
-
- HY-150145A
-
|
|
Gene Sequencing and Synthesis
|
|
Cy5-UTP sodium (10mM in Water) is a cyanine5-labeled UTP analogue that can produce fluorescent probes in vitro transcription reactions with excitation/emission wavelengths of 650/665 nm. Cy5-UTP sodium can be used in FISH, polychromatic fluorescence analysis, especially the two-color expression array combined with Cy5-UTP .
|
-
- HY-N7864
-
|
all-cis-4,7,10,13,16-Docosapentaenoic acid
|
Cell Assay Reagents
|
|
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.
|
-
- HY-B1278BR
-
|
|
Biochemical Assay Reagents
|
|
(±)-α-Tocopherol acetate (Standard) is the analytical standard of (±)-α-Tocopherol acetate. This product is intended for research and analytical applications. (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .
|
-
- HY-N7833
-
|
|
Drug Delivery
|
|
Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1525
-
|
MCH (salmon)
|
MCHR1 (GPR24)
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Endocrinology
|
|
Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.
|
-
- HY-P1542B
-
|
Catostomus urotensin I TFA
|
CRFR
|
Cardiovascular Disease
Endocrinology
|
|
Urotensin I (Catostomus urotensin I) TFA, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively .
|
-
- HY-P1525A
-
|
MCH (salmon) (TFA)
|
MCHR1 (GPR24)
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Endocrinology
|
|
Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.
|
-
- HY-P3957
-
|
|
Urotensin Receptor
|
Others
|
|
Urotensin II, teleost fish is a cyclic peptide. It can be isolated from the caudal neurosecretory system of teleost fish .
|
-
- HY-P4432
-
|
|
GnRH Receptor
|
Endocrinology
|
|
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish .
|
-
- HY-P10411
-
|
|
Bacterial
|
Infection
|
|
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
|
-
- HY-P1287
-
|
|
iGluR
|
Neurological Disease
|
|
Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa .
|
-
- HY-P1542
-
|
Catostomus urotensin I
|
CRFR
|
Cardiovascular Disease
Endocrinology
|
|
Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively .
|
-
- HY-P5697
-
|
|
Bacterial
|
Infection
|
|
Tilapia piscidin 3 is an antimicrobial peptide with antibacterial activity against gram-positive and -negative bacteria (MIC: 2.44, 2.44, 9.78, 19.55, 0.61 μg/mL for V. vulnificus 204, V. alginolyticus, S. agalactiae 819, E. faecalis BCRC 10066, S. agalactiae BCRC 10787). Tilapia piscidin 3 has hemolytic activity in fish red blood cells .
|
-
- HY-K1026
-
|
|
|
MCE TBS Powder (1 L of 1×) consists of NaCl, KCl and Tris, and is widely used as washing buffer in immunocytochemistry, FISH or ELISA, and can also be used for antibody dilution and preparation of blocking solution.
|
-
- HY-K1027
-
1 Publications Verification
|
|
MCE Rapid Blocking Buffer (TBS-T) Powder (100 mL of 1×) mainly consists of fish gelatin protein, and is widely used for the antibody blocking step in Western Blot or ELISA within 15 minutes.
|
-
- HY-K1025
-
4 Publications Verification
|
|
MCE TBS-T Powder (1 L of 1×) consists of NaCl, KCl, Tris and Tween 20, and is widely used as washing buffer in immunocytochemistry, FISH or ELISA, and can also be used for antibody dilution and preparation of blocking solution.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P990302
-
|
|
nAChR
|
Others
|
|
Anti-Human/Rat/Fish AChR Antibody (Mab35) is a rat-derived IgG1 type antibody inhibitor, targeting to human/rat/Fish AChR.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N7113
-
-
-
- HY-N6987
-
-
-
- HY-N0610
-
-
-
- HY-B2167
-
-
-
- HY-N0610R
-
-
-
- HY-113414
-
-
-
- HY-N7113R
-
|
|
Structural Classification
Natural Products
Animals
Source classification
|
Others
|
|
Squalane (Standard) is the analytical standard of Squalane. This product is intended for research and analytical applications. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities .
|
-
-
- HY-116117
-
-
-
- HY-W015370R
-
-
-
- HY-133823
-
|
C16:1 (cis-11/trans-11) Fatty acid
|
Microorganisms
Source classification
|
Endogenous Metabolite
|
|
11-Hexadecenoic acid is a monounsaturated fatty acid. 11-cis-Hexadecenoic acid and 11-trans-hexadecenoic acid have been found in ewe milk fat, and levels of each increase with dietary lipid supplementation of linseed, sunflower, olive, or fish oils. 11-trans-Hexadecenoic acid has also been found in intramuscular fat samples isolated from male and female foals. This product is a mixture of 11-cis- and 11-trans-hexadecenoic acids.
|
-
-
- HY-Y1683
-
-
-
- HY-B2167R
-
|
|
Structural Classification
Human Gut Microbiota Metabolites
Microorganisms
Ketones, Aldehydes, Acids
Source classification
Disease markers
Endogenous metabolite
Cardiovascular System Disorder
|
Endogenous Metabolite
|
|
Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid .
In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B2167S
-
|
|
|
Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
|
-
-
- HY-N0610S1
-
|
|
|
trans-Cinnamic acid-d7 is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].
|
-
-
- HY-N7113S
-
|
|
|
Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].
|
-
-
- HY-W011777S
-
|
|
|
Tricaine-d5 (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish .
|
-
-
- HY-B2167S2
-
|
|
|
Docosahexaenoic acid- 13C4 is 13C labeled Docosahexaenoic acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk .
|
-
-
- HY-115584S
-
|
|
|
Lufenuron- 13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods[1][2].
|
-
-
- HY-N0610S
-
|
|
|
trans-Cinnamic acid-d5 is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].
|
-
-
- HY-B0507S
-
|
|
|
Sulfathiazole-d4 is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-150734A
-
|
|
|
CpG ODNs
|
|
ODN 2007 sodium, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 sodium can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .
|
-
- HY-157695
-
|
C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC
|
|
Phospholipids
|
|
1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.
|
-
- HY-150734
-
|
|
|
CpG ODNs
|
|
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .
|
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