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Digitalis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Calcium Channel (1) Cholinesterase (ChE) (3) Endogenous Metabolite (1) Isotope-Labeled Compounds (1) Reference Standards (1) Sodium Channel (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (5) Inflammation/Immunology (4) Neurological Disease (5)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N12084

Isolugrandoside	Others	Cancer
Isolugrandoside is a nature product. Isolugrandoside can be isolated from Digitalis davisiana Heywood .

HY-B1238

Pronethalol 1 Publications Verification (±)-Pronethalo	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cerebral arteriovenous malformation (AVMs) .

HY-N4000

Digitonin Maximum Cited Publications 14 Publications Verification	Others	Cancer
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth . Digitonin is an natural detergent .

HY-N12799

Digitalin Digitalinum verum	Others	Others
Digitalin (Digitalinum verum) is a cardiac glycoside and can be isolated from Digitalis .

HY-N7328

Lanatoside B	Others	Cardiovascular Disease
Lanatoside B is a cardenolide that can be isolated from the leaves of Digitalis lanata .

HY-N12085

Lugrandoside	Others	Cancer
Lugrandoside is a nature product. Lugrandoside can be isolated from Digitalis davisiana Heywood .

HY-B1238A

Pronethalol hydrochloride (±)-Pronethalo hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias, and limits the cerebral arteriovenous malformation (AVMs) .

HY-N15137

Calycopterin	Endogenous Metabolite	Inflammation/Immunology
Calycopterin is a flavonoid compound that can be found in the leaves of Digitalis thapsi and exhibits immunosuppressive activity. Calycopterin is expected to be useful in the study of immune diseases .

HY-N5093

Glucodigifucoside	Others	Cancer
Glucodigifucoside, a cardenolide glycoside that could be isolated from the seeds of Digitalis purpurea, exhibits potent cytotoxicity against human renal adenocarcinoma cell line ACHN .

HY-16022

Acetyldigitoxin Digitoxin 3'''-Acetate	Others	Others
Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch .

HY-130456

AHR 10718	Sodium Channel	Cardiovascular Disease
AHR 10718 is an antiarrhythmic agent that suppresses cardiac arrhythmias induced by digitalis intoxication and myocardial infarction in the intact dog. AHR 10718 also depresses membrane responsiveness and conduction, shortens the effective refractory period of specialized conducting fibers less than action potential duration .

HY-B0882

Edrophonium chloride	Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

HY-B0882S

Edrophonium-d5 chloride	Isotope-Labeled Compounds Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Edrophonium-d₅ chloride is the deuterium labeled Edrophonium chloride (HY-B0882). Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

HY-B0882R

Edrophonium chloride (Standard)	Reference Standards Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Edrophonium chloride (Standard) is the analytical standard of Edrophonium chloride (HY-B0882). This product is intended for research and analytical applications. Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis.

HY-136677

Lnd 796	Calcium Channel	Cardiovascular Disease
LND 796 is an aminosteroidal derivative with positive inotropic effects similar to those of digitalis. It exhibits electrophysiological, toxic, and inotropic effects in normal and partially potassium-depolarized ventricular muscles. LND 796 requires higher concentrations than digoxin to induce the same toxic symptoms. It exhibits a concentration-dependent positive inotropic effect on guinea pig papillary muscles in normal potassium solution. In partially potassium-depolarized papillary muscles, LND 796 enhances both components of contraction and increases the amplitude of slow action potentials. The mechanism of positive inotropic action of LND 796 involves enhanced calcium entry in calcium channels and inhibition of sodium-potassium ATPase. Due to its expanded positive inotropic range, LND 796 may have potential application in the treatment of congestive heart failure.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12084

Isolugrandoside	Plantaginaceae Structural Classification Source classification Phenols Polyphenols Digitalis davisiana Heywood Plants	Others
Isolugrandoside is a nature product. Isolugrandoside can be isolated from Digitalis davisiana Heywood .

HY-N4000

Digitonin 10+ Cited Publications	Digitalis purpurea Linn. Structural Classification Classification of Application Fields Source classification Scrophulariaceae Plants Disease Research Fields Steroids Cancer	Others
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth . Digitonin is an natural detergent .

HY-N12799

Digitalin Digitalinum verum	Plantaginaceae Structural Classification Polysaccharides Digitalis ciliata Trautv. Source classification Plants Saccharides	Others
Digitalin (Digitalinum verum) is a cardiac glycoside and can be isolated from Digitalis .

HY-N7328

Lanatoside B	Plantaginaceae Structural Classification Cardiacglycosides Source classification Digitalis lanata Ehrh. Plants Steroids	Others
Lanatoside B is a cardenolide that can be isolated from the leaves of Digitalis lanata .

HY-N12085

Lugrandoside	Plantaginaceae Structural Classification Source classification Phenols Polyphenols Digitalis davisiana Heywood Plants	Others
Lugrandoside is a nature product. Lugrandoside can be isolated from Digitalis davisiana Heywood .

HY-N15137

Calycopterin	Plantaginaceae Structural Classification Flavonoids Flavones Source classification Plants Digitalis thapsi L.	Endogenous Metabolite
Calycopterin is a flavonoid compound that can be found in the leaves of Digitalis thapsi and exhibits immunosuppressive activity. Calycopterin is expected to be useful in the study of immune diseases .

HY-N5093

Glucodigifucoside	Digitalis purpurea Linn. Classification of Application Fields Cardiacglycosides Source classification Scrophulariaceae Plants Disease Research Fields Steroids Cancer	Others
Glucodigifucoside, a cardenolide glycoside that could be isolated from the seeds of Digitalis purpurea, exhibits potent cytotoxicity against human renal adenocarcinoma cell line ACHN .

HY-16022

Acetyldigitoxin Digitoxin 3'''-Acetate	Plantaginaceae Cardiacglycosides Source classification Stauranthus perforatus Plants Steroids	Others
Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch .

Cat. No.	Product Name	Chemical Structure

HY-B0882S

Edrophonium-d5 chloride
Edrophonium-d₅ chloride is the deuterium labeled Edrophonium chloride (HY-B0882). Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

Edrophonium-d5 chloride

Edrophonium-d₅ chloride is the deuterium labeled Edrophonium chloride (HY-B0882). Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

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Digitalis

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products