Search Result

Results for "

DPPH assay

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Aldose Reductase (1) AMPK (1) Apoptosis (2) Bacterial (3) Cholinesterase (ChE) (2) Cytochrome P450 (2) EGFR (1) Fatty Acid Synthase (FASN) (1) Fungal (3) HMG-CoA Reductase (HMGCR) (1) IFNAR (2) Influenza Virus (1) Interleukin Related (1) Lipoxygenase (1) PPAR (1) Reactive Oxygen Species (ROS) (5) Reference Standards (2) SARS-CoV (1) TNF Receptor (1)
By Research Areas:	Cancer (7) Infection (5) Inflammation/Immunology (9) Metabolic Disease (3) Neurological Disease (3)

Inhibitors & Agonists

Peptides

Natural
Products

Targets Recommended: Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8163

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside	Others	Others
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is an antioxidant with an IC₅₀ of 26.6 μM (DPPH assay) .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-N11469

Cyclobisdemethoxycurcumin	Others	Others
Cyclobisdemethoxycurcumin is an antioxidant agent with IC₅₀s of ~250 μM and 15-20 μM in DPPH radical scavenging assay and 2-DR oxidation assay, respectively .

HY-N8660

Cimicifugic acid B	Others	Metabolic Disease
Cimicifugic acid B is an antioxidant with an IC₅₀ of 21 µM in the DPPH assay .

HY-N9283

1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran	Reactive Oxygen Species (ROS)	Neurological Disease Cancer
1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC₅₀ of 28 μM, inhibits malondialdehyde (MDA) with the IC₅₀ of 71 μM, and inhibits α-glucosidase with the IC₅₀ of 6.22 μM .

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-N7904

Laricitrin 3-O-glucoside	Others	Others
Laricitrin 3-O-glucoside is an antioxidant agent. Laricitrin 3-O-glucoside correlates significantly with DPPH assay and CUPRAC assay .

HY-N3424

Kelampayoside A	Others	Inflammation/Immunology
Kelampayoside A, a natural compound, shows an EC₅₀ value of 35.7 µg/mL in DPPH assay (antioxidative activity) .

HY-N8169

10-O-Trans-p-methoxycinnamoylcatalpol	Others	Others
10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC₅₀ value of 0.37 μM/mL in DPPH free radical scavenging assay .

HY-173055

Ferroleuton	Lipoxygenase	Inflammation/Immunology
Ferroleuton is a competitive, selective inhibitor for 5-lipoxygenase with an IC₅₀ of 0.21 μM. Ferroleuton exhibits antioxidant activity in DPPH (scavenges 86% DPPH-H at 50 μM), ABTS (EC₅₀=19.42 μM) and FRAP (EC₅₀=3.32 μM) assays .

HY-N4046

Hexacosyl (E)-ferulate n-Hexacosyl trans-ferulate	Others	Others
Hexacosyl (E)-ferulate (n-Hexacosyl trans-ferulate) is an antioxidant agent that displays significant antioxidant activity in the DPPH (HY-112053) assay with the RC₅₀ (50% reduction concentration) of 0.0976 mg/mL .

HY-N1417

Sesamol 2 Publications Verification	Apoptosis	Cancer
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC₅₀=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .

HY-N3421

Koaburaside	Interleukin Related TNF Receptor Influenza Virus	Infection Inflammation/Immunology Cancer
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC₅₀ of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .

HY-N1417R

Sesamol (Standard)	Reference Standards Apoptosis	Cancer
Sesamol (Standard) is the analytical standard of Sesamol. This product is intended for research and analytical applications. Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .

HY-N3348

Lyoniside	Fungal	Infection Inflammation/Immunology
Lyoniside is a lignan glycoside with antioxidant, allelopathic and antifungal activities, which can be isolated from the rhizomes and stems of bilberry (Vaccinium myrtillus L.). Lyoniside exhibits radical scavenging properties with an IC₅₀ value of 23 μg/mL in DPPH assay. Lyoniside inhibits the mycelial growth of Fusarium oxysporum and Mucor hiemalis at 50 μg/mL with inhibitory rates of 78% and 80%, respectively .

HY-N7155

2,4,7-Trihydroxy-9,10-dihydrophenanthrene	Reactive Oxygen Species (ROS)	Inflammation/Immunology
2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene derivative that can be isolated from the air-dried whole plant of Pholidota chinensis Lindl.. 2,4,7-Trihydroxy-9,10-dihydrophenanthrene shows potent activities of IC₅₀ at 16.2 μM in *DPPH* radical-scavenging assay .

HY-105629

Populin Populoside; Salicin 6-benzoate; NSC 128308	Aldose Reductase	Metabolic Disease
Populin (Populoside) is a phenolic glucoside with antioxidant activities. Populin inhibits aldose reductase with an IC₅₀ of 18.55 μM. Populin shows IC₅₀s of 6.76 µM and 1.69 mM in DPPH radical-scavenging and ABTS ·+ radical-scavenging assays. Populin also inhibits D-Sorbitol (HY-B0400) accumulation.Populin has the potential to be used in the study of diabetic complications .

HY-161722

SARS-CoV-2 Mpro-IN-21	SARS-CoV	Infection
SARS-CoV-2 Mpro-IN-21 (compound A8) is a potent SARS-CoV-2 and OVID-19 Main Protease M ^Pro inhibitor. SARS-CoV-2 Mpro-IN-21 shows excellent antioxidant activity in DPPH assay with an IC₅₀ of 0.36 mg/mL. SARS-CoV-2 Mpro-IN-21 also exhibits better antibacterial potency against Klebsiella with an IC₅₀ of 1.19 mg/mL .

HY-N2214

7-O-Methylaloeresin A	Bacterial	Inflammation/Immunology
7-O-Methylaloeresin A is 5-methylchromone glycoside isolated from Commiphora socotrana (Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple agent resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mM, respectively. 7-O-Methylaloeresin A has antioxidant activities, gives IC50 values of 0.026 mM and 0.021 mM for DPPH and 2-deoxyribose degradation assay, respectively.

HY-N7005

Clitorin	EGFR Cytochrome P450 Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase HMG-CoA Reductase (HMGCR) PPAR AMPK	Metabolic Disease Inflammation/Immunology Cancer
Clitorin is an orally active flavonoid compound that can be isolated from Carica papaya. Clitorin is an inhibitor of EGFR (IC₅₀: 89.58 nM) and aromatase (IC₅₀: 77.41 nM). Clitorin has antioxidant and anti-tumor activities. In the DPPH and ABTS radical scavenging assays, Clitorin has IC₅₀ values of 91.96 ppm and 250.45 ppm, respectively. In addition, Clitorin can regulate lipogenesis and fatty acid oxidation and can be used in the research of non-alcoholic fatty liver disease .

HY-159143

BChE-IN-33	Cholinesterase (ChE) Cytochrome P450	Neurological Disease
BChE-IN-33 (compound 4r), an arylaminonaphthol derivative, is a potent butyrylcholinesterase (BChE) inhibitor with an IC₅₀ of 14.78 µM. BChE-IN-33 also inhibits CYP2C19, CYP2C9, CYP2D6. BChE-IN-33 shows potent antioxidant activity with IC₅₀ values of 150.48 μM, 2.56 μM and 4.61 μM by DPPH, ABTS, Ferric-phenanthroline assay, respectively. BChE-IN-33 has the potential for Alzheimer research .

HY-174399

AChE/BChE-IN-27	Cholinesterase (ChE) Reactive Oxygen Species (ROS)	Neurological Disease
AChE/BChE-IN-27 is a blood-brain barrier-permeable mixed inhibitor (Pe = 4.12) of AChE and BChE, with IC₅₀ values of 3.72 μM and 9.65 μM, respectively. AChE/BChE-IN-27 has potent antioxidant activity with an IC₅₀ value of 6.32 μM in the DPPH (HY-112053) assay and also exhibits potent in vitro antioxidant activity. AChE/BChE-IN-27 exhibits metal chelating properties. AChE/BChE-IN-27 has neuroprotective potential against oxidative stress. AChE/BChE-IN-27 significantly reduces intracellular reactive oxygen species (ROS). In in vivo experiments, AChE/BChE-IN-27 effectively restored AChE and BChE levels, improved cognition, and can be used for Alzheimer's disease (AD) .

Cat. No.	Product Name	Target	Research Area

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside	Flavonols Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Sophora japonica (L.) Schott Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is an antioxidant with an IC₅₀ of 26.6 μM (DPPH assay) .

Cyclo(L-Phe-L-Pro)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

Cyclobisdemethoxycurcumin	Structural Classification Monophenols Source classification Phenols Plants Curcuma longa Zingiberaceae	Others
Cyclobisdemethoxycurcumin is an antioxidant agent with IC₅₀s of ~250 μM and 15-20 μM in DPPH radical scavenging assay and 2-DR oxidation assay, respectively .

Cimicifugic acid B	Structural Classification Source classification Ranunculaceae Phenols Polyphenols Plants Cimicifuga racemosa (L.) Nutt.	Others
Cimicifugic acid B is an antioxidant with an IC₅₀ of 21 µM in the DPPH assay .

1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran	Microorganisms Source classification Phenols Polyphenols	Reactive Oxygen Species (ROS)
1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC₅₀ of 28 μM, inhibits malondialdehyde (MDA) with the IC₅₀ of 71 μM, and inhibits α-glucosidase with the IC₅₀ of 6.22 μM .

Cyclo(L-Phe-L-Pro) (Standard)	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

Laricitrin 3-O-glucoside	Structural Classification Flavonoids Flavones Pinaceae Cedrus atlantica (Endlicher) Manetti ex Carriere Source classification Plants	Others
Laricitrin 3-O-glucoside is an antioxidant agent. Laricitrin 3-O-glucoside correlates significantly with DPPH assay and CUPRAC assay .

Kelampayoside A	Structural Classification Cinnamomum cassia (L.) D. Don Ketones, Aldehydes, Acids Source classification Plants Lauraceae	Others
Kelampayoside A, a natural compound, shows an EC₅₀ value of 35.7 µg/mL in DPPH assay (antioxidative activity) .

10-O-Trans-p-methoxycinnamoylcatalpol	Premna IntegrifoliaL. Classification of Application Fields Verbenaceae Source classification Other Diseases Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields	Others
10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC₅₀ value of 0.37 μM/mL in DPPH free radical scavenging assay .

Hexacosyl (E)-ferulate n-Hexacosyl trans-ferulate	Structural Classification Monophenols Source classification Dendranthema morifolium (Ramat.) Tzvel. Phenols Plants Compositae	Others
Hexacosyl (E)-ferulate (n-Hexacosyl trans-ferulate) is an antioxidant agent that displays significant antioxidant activity in the DPPH (HY-112053) assay with the RC₅₀ (50% reduction concentration) of 0.0976 mg/mL .

Sesamol 2 Publications Verification	Structural Classification Monophenols Classification of Application Fields Sesamum indicum Linn. Source classification Phenols Pedaliaceae Plants Disease Research Fields Cancer	Apoptosis
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC₅₀=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .

Koaburaside	Structural Classification Eucommia ulmoides Oliver Source classification Eucommiaceae Plants Saccharides Monosaccharides	Interleukin Related TNF Receptor Influenza Virus
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC₅₀ of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .

Sesamol (Standard)	Structural Classification Monophenols Sesamum indicum Linn. Source classification Phenols Pedaliaceae Plants	Reference Standards Apoptosis
Sesamol (Standard) is the analytical standard of Sesamol. This product is intended for research and analytical applications. Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .

Lyoniside	Structural Classification Vaccinium myrtillus Linn. Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Ericaceae	Fungal
Lyoniside is a lignan glycoside with antioxidant, allelopathic and antifungal activities, which can be isolated from the rhizomes and stems of bilberry (Vaccinium myrtillus L.). Lyoniside exhibits radical scavenging properties with an IC₅₀ value of 23 μg/mL in DPPH assay. Lyoniside inhibits the mycelial growth of Fusarium oxysporum and Mucor hiemalis at 50 μg/mL with inhibitory rates of 78% and 80%, respectively .

2,4,7-Trihydroxy-9,10-dihydrophenanthrene	Classification of Application Fields Orchidaceae Source classification Phenols Polyphenols Pholidota chinensis Lindl. Plants Disease Research Fields Inflammation/Immunology	Reactive Oxygen Species (ROS)
2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene derivative that can be isolated from the air-dried whole plant of Pholidota chinensis Lindl.. 2,4,7-Trihydroxy-9,10-dihydrophenanthrene shows potent activities of IC₅₀ at 16.2 μM in *DPPH* radical-scavenging assay .

Populin Populoside; Salicin 6-benzoate; NSC 128308	Structural Classification Populus × berolinensis K. Koch Source classification Plants Saccharides Monosaccharides Salicaceae	Aldose Reductase
Populin (Populoside) is a phenolic glucoside with antioxidant activities. Populin inhibits aldose reductase with an IC₅₀ of 18.55 μM. Populin shows IC₅₀s of 6.76 µM and 1.69 mM in DPPH radical-scavenging and ABTS ·+ radical-scavenging assays. Populin also inhibits D-Sorbitol (HY-B0400) accumulation.Populin has the potential to be used in the study of diabetic complications .

7-O-Methylaloeresin A	Structural Classification Monophenols Liliaceae Classification of Application Fields Simple Phenylpropanols Source classification Phenols Aloe vera (L.) Burm. f. Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Bacterial
7-O-Methylaloeresin A is 5-methylchromone glycoside isolated from Commiphora socotrana (Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple agent resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mM, respectively. 7-O-Methylaloeresin A has antioxidant activities, gives IC50 values of 0.026 mM and 0.021 mM for DPPH and 2-deoxyribose degradation assay, respectively.

Clitorin	Flavonols Structural Classification Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	EGFR Cytochrome P450 Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase HMG-CoA Reductase (HMGCR) PPAR AMPK
Clitorin is an orally active flavonoid compound that can be isolated from Carica papaya. Clitorin is an inhibitor of EGFR (IC₅₀: 89.58 nM) and aromatase (IC₅₀: 77.41 nM). Clitorin has antioxidant and anti-tumor activities. In the DPPH and ABTS radical scavenging assays, Clitorin has IC₅₀ values of 91.96 ppm and 250.45 ppm, respectively. In addition, Clitorin can regulate lipogenesis and fatty acid oxidation and can be used in the research of non-alcoholic fatty liver disease .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

DPPH assay

Inhibitors & Agonists

Peptides

NaturalProducts

Natural
Products