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DPPH,

" in MedChemExpress (MCE) Product Catalog:

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112053

*DPPH* Maximum Cited Publications 23 Publications Verification 2,2-Diphenyl-1-picrylhydrazyl	Reactive Oxygen Species	Metabolic Disease
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .

HY-N3141

Olivil (-)-Olivile; Vladinol C	Others	Others
Olivil ((-)-Olivile) is a lignan that has weak DPPH radical-scavenging activity (EC₅₀: 176 μM) .

HY-N6043

Hydroxytyrosol acetate	Others	Inflammation/Immunology
Hydroxytyrosol acetate is found in the olive oil with an antioxidant activity. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol .

HY-112053R

DPPH (Standard)	Reactive Oxygen Species	Metabolic Disease
DPPH (Standard) is the analytical standard of DPPH. This product is intended for research and analytical applications. DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .

HY-121153

Altenusin Alutenusin	FXR	Others
Altenusin shows markedly DPPH radical scavenging activities.

HY-N8660

Cimicifugic acid B	Others	Metabolic Disease
Cimicifugic acid B is an antioxidant with an IC₅₀ of 21 µM in the DPPH assay .

HY-173055

Ferroleuton	Lipoxygenase	Inflammation/Immunology
Ferroleuton is a competitive, selective inhibitor for 5-lipoxygenase with an IC₅₀ of 0.21 μM. Ferroleuton exhibits antioxidant activity in DPPH (scavenges 86% DPPH-H at 50 μM), ABTS (EC₅₀=19.42 μM) and FRAP (EC₅₀=3.32 μM) assays .

HY-W018643A

(E)-Ferulic acid methyl ester Methyl (E)-ferulate	COX	Others
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N3424

Kelampayoside A	Others	Inflammation/Immunology
Kelampayoside A, a natural compound, shows an EC₅₀ value of 35.7 µg/mL in DPPH assay (antioxidative activity) .

HY-N3858

Erythristemine	Others	Inflammation/Immunology
Erythristemine is an alkaloid that can be isolated from Erythrina lysistemon. Erythristemine has weak DPPH radical scavenging properties .

HY-111523

Isomahanine	p38 MAPK Apoptosis Autophagy Caspase	Metabolic Disease
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

HY-N11895

Isorabaichromone	Reactive Oxygen Species	Inflammation/Immunology
Isorabaichromone is a potent antioxidant agent. Isorabaichromone shows a potent antioxidative activity and exhibits DPPH radical and superoxide anion scavenging activities .

HY-155346

Free radical scavenger 1	Others	Others
Free radical scavenger 1 (compound 8) shows scavenging activity against the *DPPH* radical, with the IC₅₀ of 43.39 μg/ml .

HY-133965

Cinchonain IIa	Others	Inflammation/Immunology
Cinchonain IIa is an antioxidant agent with EC₅₀s of 6.8 μM and 26.5 μM for DPPH and PMS-NADH .

HY-N6672

Caulophylline B	Others	Inflammation/Immunology
Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical .

HY-N11655

Antioxidant agent-10	Others	Others
Antioxidant agent-10 (Compound 3) is an antioxidant agent that exhibits moderate DPPH scavenging activity with an EC₅₀ of 33.2 μg/mL .

HY-N7931

Regaloside A 1 Publications Verification	NO Synthase NF-κB	Inflammation/Immunology
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity .

HY-133183

Urolignoside	Biochemical Assay Reagents	Others
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-N3985

Gyrophoric acid	Others	Cancer
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC₅₀ value of 105.75 μg/ml .

HY-124496

Piperitenone	Mitochondrial Metabolism Reactive Oxygen Species	Others
Piperitenone is a terpenoid, and exhibits antioxidant activity. Piperitenone scavenges DPPH free radicals with an IC₅₀ of 22.7 μg/mL, and inhibits the peroxidation of linoleic acid .

HY-N7904

Laricitrin 3-O-glucoside	Others	Others
Laricitrin 3-O-glucoside is an antioxidant agent. Laricitrin 3-O-glucoside correlates significantly with DPPH assay and CUPRAC assay .

HY-N8579

Eugenyl benzoate	Others	Inflammation/Immunology
Eugenyl benzoate has the potency for scavenging of *DPPH* radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors .

HY-N3349A

(-)-Lyoniresinol	Reactive Oxygen Species	Others
(-)-Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. (-)-Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM .

HY-N3349

Lyoniresinol	Others	Others
Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM .

HY-N9447

Norbergenin 1 Publications Verification	Reactive Oxygen Species	Neurological Disease
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-N8169

10-O-Trans-p-methoxycinnamoylcatalpol	Others	Others
10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC₅₀ value of 0.37 μM/mL in DPPH free radical scavenging assay .

HY-N13185

POPi	Endogenous Metabolite	Others
POPi (phloridzin oxidation product i) is a colorless oxidation product of phloridzin catalyzed by the apple polyphenol oxidase with DPPH radicalscavenging activity. POPi can be utilized in antioxidant research .

HY-N11469

Cyclobisdemethoxycurcumin	Others	Others
Cyclobisdemethoxycurcumin is an antioxidant agent with IC₅₀s of ~250 μM and 15-20 μM in DPPH radical scavenging assay and 2-DR oxidation assay, respectively .

HY-N4111

Wushanicaritin 1 Publications Verification	Others	Inflammation/Immunology Cancer
Wushanicaritin exhibits significant antioxidant activity (IC₅₀=35.3 μM) in DPPH radical scavenging activity tests. Antitumor effects and anti-inflammatory property .

HY-N13128

Icaritin-3-O-rhamnoside	Others	Others
Icaritin-3-O-rhamnoside (compound 20) is a flavonoid compound that exhibits DPPH radical scavenging activity (IC50=227.9 μM) .

HY-N10985

Xanthone V1a	Others	Inflammation/Immunology Cancer
Xanthone V1a has antioxidant activity against the *DPPH* radical (IC₅₀: 10.43 µM). Xanthone V1a has cytotoxicity against cancer cells .

HY-N12897

JBIR-94	Others	Others
JBIR-94 is a phenolic compound and can be isolated from Streptomyces. JBIR-94 has DPPH radical scavenging activity with an IC₅₀ value of 11.4 μM .

HY-N7518

Eulophiol	Others	Inflammation/Immunology
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

HY-121811

Pongamol Lanceolatin C	Glycosidase	Metabolic Disease Inflammation/Immunology
Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC₅₀=103.5 μM) and has free-radical (DPPH) scavenging,antihyperglycemic, and antihyperglycemic activities .

HY-N1205

Spathulenol	Others	Cancer
Spathulenol is isolated from Aristolochia yunnanensis, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC₅₀ of 85.60 μg/mL in the DPPH system ^[1].

HY-N12941

Macarangin	Reactive Oxygen Species NOD-like Receptor (NLR)	Inflammation/Immunology
Macarangin can be isolated from propolis. Macarangin has DPPH radical-scavenging activity and shows anti-inflammatory activities via inhibiting the activation process of NLRP3 inflammasome .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Others	Neurological Disease
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-N10020

Patulitrin	Lipoxygenase	Inflammation/Immunology
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-N12862

Floramanoside A	Aldose Reductase	Inflammation/Immunology
Floramanoside A is a flavonol glycoside that can be isolated from the flowers of Abelmouschus manihot. Floramanoside A has DPPH scavenging (IC₅₀: 10.1 μM) and aldose reductase inhibition activities (IC₅₀: 17.8 μM) .

HY-130294

Pyracrenic acid	Elastase	Inflammation/Immunology
Pyracrenic acid is an elastase inhibitor (IC₅₀ = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity .

HY-113121

Vanillylmandelic acid 2 Publications Verification	Drug Metabolite Endogenous Metabolite	Cardiovascular Disease
Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC₅₀ value of 33 μM .

HY-W274194

Antioxidant agent-7	Reactive Oxygen Species	Others
Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC₅₀ value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical .

HY-N4046

Hexacosyl (E)-ferulate n-Hexacosyl trans-ferulate	Others	Others
Hexacosyl (E)-ferulate (n-Hexacosyl trans-ferulate) is an antioxidant agent that displays significant antioxidant activity in the DPPH (HY-112053) assay with the RC₅₀ (50% reduction concentration) of 0.0976 mg/mL .

HY-111898

Epirosmanol	Others	Cancer
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .

HY-N12871

Floramanoside D	Aldose Reductase	Others
Floramanoside D is a flavonol glycoside. Floramanoside D inhibits aldose reductase (IC₅₀ is 2.2 μM), scavenges the 2,2-diphenyl-1-picrylhydrazyl (DPPH) (SC₅₀ is 12.5 μM) .

HY-W357738

Urease-IN-14	Bacterial Urease	Infection
Urease-IN-14 (compound 15) is an urease inhibitor and antioxidant. Urease-IN-14 shows DPPH radical scavenging and urease inhibitory activities with IC₅₀ values 151.7 μM and 41.6 μM, respectively .

HY-W416228

1-O-Caffeoyl-β-D-glucopyranose	Reactive Oxygen Species	Others
1-O-Caffeoyl-β-D-glucopyranose, a phenylpropanoid compound derived from Illicium majus, exhibits significant antioxidant activity and can scavenge DPPH radicals in vitro, with an IC₅₀ value of 37.7 μM .

HY-N1417

Sesamol 1 Publications Verification	Apoptosis	Cancer
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC₅₀=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .

HY-W001542

5-Hydroxyoxindole	Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
5-Hydroxyoxindole is a structural analog of uric acid. 5-Hydroxyoxindole has *DPPH* radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-N8163

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside	Others	Others
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is an antioxidant with an IC₅₀ of 26.6 μM (DPPH assay) .

Cat. No.	Product Name	Type

HY-D0168

Orcinol

3,5-Dihydroxytoluene

Dyes

Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

Cat. No.	Product Name	Target	Research Area

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P5318

MDYYFEER	Reactive Oxygen Species	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316

MHLWAAK	Peptides	Inflammation/Immunology
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316A

MHLWAAK TFA	Peptides	Inflammation/Immunology
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318A

MDYYFEER TFA	Peptides	Inflammation/Immunology
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317A

MAQAAEYYR TFA	Reactive Oxygen Species	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Fungal Bacterial IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

Cat. No.	Product Name	Category	Target	Chemical Structure