Search Result
Results for "
DMTS
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
16
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-104014
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Others
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DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
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- HY-43060
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- HY-104017
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis .
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- HY-45409
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2'-F-dU Phosphoramidite
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
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- HY-N11421
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23-DMT; 23-Demycinosyltylosin
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Bacterial
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Infection
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23-O-Demycinosyltylosin (23-DMT) is a 23-O-demycinosyltylosin (DMT) acyl derivative with antibacterial activity .
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- HY-150658S
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-
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- HY-W854187
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5'-DMT-2'-OMe-rG(N-Ac) Phosphoramidite
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DNA/RNA Synthesis
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Others
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2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac)) Phosporamiditeyes 2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac))Phosphoramidite.
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- HY-W013068S1
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- HY-W013068S3
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- HY-P5131
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Opioid Receptor
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Others
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[Dmt1]DALDA is a potent and long-acting analgesic binds to the mu opioid receptor with high affinity and selectivity. [Dmt1]DALDA is a full agonist at hMOR (Kd = 0.199 nM) and hDOR, but only partial agonist against hKOR .
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![[Dmt1]DALDA](//file.medchemexpress.eu/product_pic/hy-p5131.gif)
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- HY-W013068S2
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-
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- HY-W425093
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-
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- HY-W013059S1
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DA-CE phosphoramidite-15N5
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-W036167
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DNA/RNA Synthesis
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Others
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DMT-2'-F-dA Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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-
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- HY-153249
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DNA/RNA Synthesis
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Others
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DMT-2'-F-Cytidine Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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-
-
- HY-168014
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-
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- HY-W115309
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5'-DMT-2'-F-ibu-dG
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
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-
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- HY-W010744
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5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
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Nucleoside Antimetabolite/Analog
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Others
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DMT-dI (5'-O-DMT-dI) is a deoxyribonucleoside containing a hypoxanthine base. DMT-dI can be used to prepare convertible nucleoside derivatives to prepare modified oligonucleotides complementary to target genes for gene editing. DMT-dI can be used to study various conditions, disorders or diseases modified by adenosine .
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- HY-W013068S
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-
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- HY-W579407
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DNA/RNA Synthesis
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Others
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DMT-2'-OMe-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-153251
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DNA/RNA Synthesis
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Others
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DMT-2'-O-Methylguanosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W018179
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-
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- HY-153253
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DNA/RNA Synthesis
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Others
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DMT-2'-O-Methyladenosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W579408
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DNA/RNA Synthesis
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Others
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DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W093086
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-
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- HY-126302
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Ferroportin
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Metabolic Disease
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DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo .
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- HY-21713
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DNA/RNA Synthesis
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Others
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DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W013059S
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DA-CE phosphoramidite-13C10,15N5
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-W008849S
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- HY-W783407
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5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite
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DNA/RNA Synthesis
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Others
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Ac-rG (5'-DMT-2'-TBDMS-rG(N-Ac)) Phosporamidite is an acetylated guanosine ribonucleotide.
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- HY-W579410
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DNA/RNA Synthesis
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Others
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DMT-2'-F-6-chloro-dA phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W013059S2
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DA-CE phosphoramidite-d9
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite-d9 (DA-CE phosphoramidite-d9) is deuterium labeled DMT-dA(bz) Phosphoramidite (HY-W013059). DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
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- HY-W008848S1
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-
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- HY-W048489
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2'-O-MOE-Tr (5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine) is a nucleoside analog containing a dimethoxytrityl (DMT) group, commonly used in the synthesis of nucleic acids.
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- HY-W013059R
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DA-CE phosphoramidite (Standard)
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Reference Standards
DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is a phosphoramide monomer for the synthesis of oligonucleotides (ONs) through formation of DNA dimers and trimers via mechanochemistry .
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- HY-177197
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- HY-177196
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-
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- HY-169460
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-
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- HY-W008848S
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- HY-160884
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DNA/RNA Synthesis
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Others
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DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides .
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-
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- HY-169785
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7-TMT
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5-HT Receptor
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Neurological Disease
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7-Methyl DMT (7-TMT) is a 5-HT2 receptor agonist. Structurally, 7-Methyl DMT is a tryptamine derivative. It can be used as an analytical reference standard for the psychoactive substance DOM. 7-Methyl DMT is also used in research in the field of neurological diseases .
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- HY-138579
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DMT-2'-O-Methyl-rG(ib) Phosphoramidite
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Nucleoside Antimetabolite/Analog
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Cancer
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2'-OMe-G(ibu) Phosphoramidite (DMT-2'-O-Methyl-rG(ib) Phosphoramidite) is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis .
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- HY-45491
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2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
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Nucleoside Antimetabolite/Analog
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Others
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Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
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- HY-145464
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-
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- HY-W700549
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-
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- HY-126301
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Ferroportin
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Inflammation/Immunology
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DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo .
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- HY-46317
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DNA/RNA Synthesis
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Others
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DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding .
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- HY-W101391
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2'-O-Me-U Phosphoramidite
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DNA/RNA Synthesis
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Others
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DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis .
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- HY-21997
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DNA/RNA Synthesis
Drug Intermediate
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Others
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DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
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- HY-177198
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- HY-W013059A
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L-DA-CE phosphoramidite
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DNA/RNA Synthesis
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Others
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DMT-L-dA(bz) Phosphoramidite (L-DA-CE phosphoramidite; compound 20c) is typically used in the synthesis of DNA. DMT-L-dA(bz) Phosphoramidite can be used in studying DNA-drug interactions .
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- HY-164252
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5′-O-Trityl-2′-deoxy-2′-fluorouridine
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DNA/RNA Synthesis
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Others
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DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
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- HY-W061439
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Nucleoside Antimetabolite/Analog
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Others
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(3R,5S)-5-O-DMT-3-pyrrolidinol is a compound with a dimethoxytrityl (DMT) protecting group and a 3-pyrrolidinol structure. (3R,5S)-5-O-DMT-3-pyrrolidinol can be used in the synthesis of nucleic acids.
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- HY-138607
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- HY-138613
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- HY-W114886
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- HY-W115186
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154413
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-45492
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2'-F-ibu-dG Phosphoramidite
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
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- HY-W013068
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- HY-177200
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- HY-W048482S4
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DMT-2'O-TBDMS-rU phosphoramidite-15N
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-138601
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- HY-W1119946
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Nucleoside Antimetabolite/Analog
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Others
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(3R,5S)-5-O-DMT-3-pyrrolidinol-benzyl laurate is a laurate derivative with a dimethoxytrityl (DMT) protecting group and a 3-pyrrolidinol structure. (3R,5S)-5-O-DMT-3-pyrrolidinol-benzyl laurate can be used for oligonucleotide modification or as a lipid-soluble delivery vehicle.
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- HY-W013059
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DA-CE phosphoramidite
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-W570893
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DNA/RNA Synthesis
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Others
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DMT-LNA-G phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W008849
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- HY-W048482S3
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DMT-2'O-TBDMS-rU phosphoramidite-15N2
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49210
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DNA/RNA Synthesis
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Others
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DMT-locG(ib) Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49000
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DNA/RNA Synthesis
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Others
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DMT-locMeC(bz) phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-138608
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-
- HY-138585
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-
- HY-138581
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-
- HY-W048482S2
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DMT-2'O-TBDMS-rU phosphoramidite-13C9
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49200
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-164181
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-
- HY-138609
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- HY-138605
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-
- HY-138606
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- HY-139988
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DNA/RNA Synthesis
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Others
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2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-B1311
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SKF-525A; U-5446; RP-5171
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Cytochrome P450
Monoamine Oxidase
Bcl-2 Family
Survivin
PARP
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Neurological Disease
Inflammation/Immunology
Cancer
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|
Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases .
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- HY-D2737
-
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BHQ-2 DMT amidite
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Fluorescent Dye
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Others
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DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
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- HY-W460666
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Drug Intermediate
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Cancer
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5'-O-DMT-N2-Ibu-2'-OMe-G is a crucial intermediate for the synthesis of antisense oligonucleotides. 5'-O-DMT-N2-Ibu-2'-OMe-G is involved in constructing antisense oligonucleotides with specific sequences, which can bind complementarily to the targeted mRNA. 5'-O-DMT-N2-Ibu-2'-OMe-G blocks the translation process of mRNA, thereby inhibiting the expression of specific proteins and playing a role in regulating gene expression. 5'-O-DMT-N2-Ibu-2'-OMe-G is promising for research of genetic diseases and tumors .
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- HY-164249
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DNA/RNA Synthesis
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Others
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DMT-rG(Ac)Is with DMTProtecting Group (Protect 5'end), acetylated guanosine ribonucleotide.
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- HY-W881217
-
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DNA/RNA Synthesis
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Others
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DMT-iBu-G-(S)-GNA Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
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- HY-B1311R
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SKF-525A (Standard); U-5446 (Standard); RP-5171 (Standard)
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Reference Standards
Cytochrome P450
Monoamine Oxidase
Bcl-2 Family
Survivin
PARP
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Neurological Disease
Inflammation/Immunology
Cancer
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|
Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [4] .
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- HY-W102322
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- HY-21545
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- HY-138610
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- HY-W008848
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- HY-132136
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DNA/RNA Synthesis
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Others
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DMT-dU-CE Phosphoramidite is a nucleoside molecule that can be used in DNA synthesis and DNA sequencing .
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- HY-154366
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N1-Methylpseudouridine CEP
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Nucleoside Antimetabolite/Analog
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Cancer
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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W784557
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Biochemical Assay Reagents
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Others
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O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
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- HY-138586
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- HY-D2742
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BHQ-1 DMT amidite
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Fluorescent Dye
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Others
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DMT-BH1 amidite (BHQ-1 DMT amidite) is a true dark quencher with broad absorption curve which covers the visible spectrum with maximum in green to yellow region. It is used for the synthesis of dual labeled oligonucleotide probes for qPCR bearing 5'-quencher DusQ 1 and other FRET applications for multiplexing assays.
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- HY-W048482S1
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DMT-2'O-TBDMS-rU phosphoramidite-13C9,15N2
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W793155
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Nucleoside Antimetabolite/Analog
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Others
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N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that is structurally related to the natural nucleotide adenosine. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides.
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- HY-138600
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-
- HY-170049
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- HY-W008848A
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-
- HY-W048482S
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DMT-2'O-TBDMS-rU phosphoramidite-13C2,d1
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-138604
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-
- HY-138106
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Amino Acid Derivatives
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Others
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Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
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- HY-138614
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- HY-138611
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- HY-138603
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-
- HY-138612
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- HY-43059
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-
- HY-W000665
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Dmt
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Opioid Receptor
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Neurological Disease
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2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides .
|
-
- HY-W048494
-
|
N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N4-Bz-5-Me-DMT-2'-O-MOE-Cr (N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine) is a nucleoside analog containing a dimethoxytrityl (DMT) group, commonly used in the synthesis of nucleic acids.
|
-
- HY-W091754
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.
|
-
- HY-W077279
-
|
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
|
DNA/RNA Synthesis
|
Others
|
|
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
|
-
- HY-21601
-
-
- HY-12619
-
|
|
HSP
|
Cancer
|
|
DMT003096 is a HSP70 inhibitor. HSP70 has been reported to be upregulated in various cancers including breast, lung, colon, and cervix .
|
-
- HY-W336559
-
|
|
DNA/RNA Synthesis
|
Others
|
|
5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-171114
-
|
|
Liposome
|
Others
|
|
DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body .
|
-
- HY-43058
-
-
- HY-W1119952
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(3R,5S)-5-O-DMT-3-pyrrolidinol-12-oxododecanoic acid is a biochemical assay reagent that can be used to synthesize a variety of compounds. (3R,5S)-5-O-DMT-3-pyrrolidinol-12-oxododecanoic acid is the intermediate for the synthesis of complex compounds and building blocks.
|
-
- HY-173175
-
-
- HY-W1119944
-
-
- HY-138602
-
-
- HY-138598
-
-
- HY-20140
-
-
- HY-48873
-
|
|
DNA/RNA Synthesis
|
Others
|
|
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-46369
-
|
|
DNA/RNA Synthesis
|
Others
|
|
1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W042357
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Ac-rC Phosphoramidite is a phosphoramidite containing 5’ DMT and the nucleoside cytiding with Acetyl base protection. Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA) .
|
-
- HY-W087199
-
|
|
DNA/RNA Synthesis
|
Others
|
|
N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W114328
-
|
N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides .
|
-
- HY-152970
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-W008662
-
|
|
Filovirus
|
Infection
|
|
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
|
-
- HY-W726201
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.
|
-
- HY-104039
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-112144
-
|
|
HIF/HIF Prolyl-Hydroxylase
|
Metabolic Disease
Inflammation/Immunology
|
|
TP0463518 is an orally active, competitive pan-inhibitor of hypoxia-inducible factor prolyl hydroxylases PHD1/2/3. TP0463518 competitively inhibits human PHD1 (IC50=18 nM), PHD2 (Ki=5.3 nM), and PHD3 (IC50=63 nM), and targets monkey PHD2 with an IC50 of 22 nM. TP0463518 inhibits PHD-catalyzed hydroxylation to stabilize HIFα, thereby upregulating erythropoietin (EPO) expression and enhancing intestinal iron absorption (such as increased DMT-1 and dCYTb expression), improving anemia. TP0463518 is mainly used for the research of renal anemia and inflammatory anemia .
|
-
- HY-W1119957
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5'(E)-VP-2'-OMe-U Phosphoramidite is a phosphoramidite that contains 5’ DMT and uridine with 2’-O-methyl protection. 5'(E)-VP-2'-OMe-U Phosphoramidite can be used to synthesize oligonucleotide.
|
-
- HY-W1119943
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-OMe-8-Me-DMF-G Phosphoramidite is a phosphoramidite compound containing modified guanine (G) and a dimethoxytrityl (DMT) group. 2'-OMe-8-Me-DMF-G Phosphoramidite can be used in RNA oligonucleotide synthesis.
|
-
- HY-W010702
-
|
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
|
DNA/RNA Synthesis
|
Others
|
|
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides .
|
-
- HY-154019
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154410
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-169466
-
|
|
Drug Derivative
|
Neurological Disease
|
|
5-Methoxy-N,N-dimethyltryptamine Nb-oxide is an indole alkaloid. 5-Methoxy-N,N-dimethyltryptamine Nb-oxide is the N-oxide form of 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), which is a known psychoactive substance .
|
-
- HY-101528
-
|
|
iGluR
|
Neurological Disease
|
|
IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging .
|
-
- HY-152978
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154309
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154604
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-154363
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154267
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154450
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154229
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154030
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152979
-
|
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154441
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154221
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154260
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154207
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-124703
-
|
|
Ferroportin
|
Others
|
|
Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 (DMT1), with a Ki of 20 μM (hDMT1). Pyrimidinone 8 does not affect hDMT1 cell surface expression and shows no dependence with the extracellular pH. Pyrimidinone 8 can inhibit hDMT1-mediated iron uptake, with an IC50 of 13.8 μM .
|
-
- HY-152988
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-152973
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154350
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-138589
-
|
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Infection
Cancer
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154548
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-152984
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W097792
-
|
5'-O-DMT-dU
|
DNA/RNA Synthesis
|
Others
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
-
- HY-154464
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-45281
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-152983
-
|
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154419
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154339
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W141392
-
|
|
Nucleoside Antimetabolite/Analog
Xanthine Oxidase
|
Cancer
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-W392836
-
|
|
Nucleoside Antimetabolite/Analog
Xanthine Oxidase
|
Cancer
|
|
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-W010706
-
|
5'-O-DMT-N4-Bz-dC
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2737
-
|
BHQ-2 DMT amidite
|
Fluorescent Dyes/Probes
|
|
DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
|
| Cat. No. |
Product Name |
Type |
-
- HY-W093086
-
-
- HY-21997
-
|
|
Gene Sequencing and Synthesis
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-W013068
-
-
- HY-W013059
-
-
- HY-W008849
-
-
- HY-W008848
-
|
|
Gene Sequencing and Synthesis
|
|
DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
- HY-132136
-
-
- HY-W077279
-
|
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
|
Gene Sequencing and Synthesis
|
|
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
|
-
- HY-W097792
-
|
5'-O-DMT-dU
|
Gene Sequencing and Synthesis
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
-
- HY-W013059R
-
|
DA-CE phosphoramidite (Standard)
|
Gene Sequencing and Synthesis
|
|
DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is a phosphoramide monomer for the synthesis of oligonucleotides (ONs) through formation of DNA dimers and trimers via mechanochemistry .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-138106
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
|
-
- HY-W000665
-
|
Dmt
|
Opioid Receptor
|
Neurological Disease
|
|
2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides .
|
-
- HY-P5131
-
|
|
Opioid Receptor
|
Others
|
|
[Dmt1]DALDA is a potent and long-acting analgesic binds to the mu opioid receptor with high affinity and selectivity. [Dmt1]DALDA is a full agonist at hMOR (Kd = 0.199 nM) and hDOR, but only partial agonist against hKOR .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-150658S
-
|
|
|
DMT-2′O-TBDMS-rA(ac)-1- 15N phosphoramidite is the 15N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite .
|
-
-
- HY-W013068S1
-
|
|
|
DMT-dT Phosphoramidite- 15N2 is the 15N labeled DMT-dT Phosphoramidite . DMT-dT Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W013068S3
-
|
|
|
DMT-dT Phosphoramidite-d11 is deuterium labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-W013068S2
-
|
|
|
DMT-dT Phosphoramidite- 13C is 13C-labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-W013059S1
-
|
|
|
DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W013068S
-
|
|
|
DMT-dT Phosphoramidite- 13C10, 15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite . DMT-dT Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W013059S
-
|
|
|
DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W008849S
-
|
|
|
DMT-dC(bz) Phosphoramidite- 13C9, 15N3 is the 13C and 15N labeled DMT-dC(bz) Phosphoramidite . DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W013059S2
-
|
|
|
DMT-dA(bz) Phosphoramidite-d9 (DA-CE phosphoramidite-d9) is deuterium labeled DMT-dA(bz) Phosphoramidite (HY-W013059). DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-W008848S1
-
|
|
|
DMT-dG(ib) Phosphoramidite- 15N5 is the 15N labeled DMT-dG(ib) Phosphoramidite (HY-W008848). DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
-
- HY-W008848S
-
|
|
|
DMT-dG(ib) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dG(ib) Phosphoramidite (HY-W008848). DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
-
- HY-W048482S4
-
|
|
|
rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S3
-
|
|
|
rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S2
-
|
|
|
rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S1
-
|
|
|
rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S
-
|
|
|
rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-104014
-
|
|
|
Nucleoside Phosphoramidites
Guanine
|
|
DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
|
-
- HY-43060
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-DMT-3'-TBDMS-ibu-rG is is a modified nucleoside. 5'-DMT-3'-TBDMS-ibu-rG can be used in deoxyribonucleic acid synthesis.
|
-
- HY-104017
-
|
|
|
Nucleoside Phosphoramidites
Adenine
|
|
DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis .
|
-
- HY-45409
-
|
2'-F-dU Phosphoramidite
|
|
Nucleoside Phosphoramidites
Uracil
|
|
DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
|
-
- HY-W115309
-
|
5'-DMT-2'-F-ibu-dG
|
|
Nucleoside Analogs
Guanosine
|
|
DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
|
-
- HY-W010744
-
|
5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
|
|
Nucleoside Analogs
Inosine
|
|
DMT-dI (5'-O-DMT-dI) is a deoxyribonucleoside containing a hypoxanthine base. DMT-dI can be used to prepare convertible nucleoside derivatives to prepare modified oligonucleotides complementary to target genes for gene editing. DMT-dI can be used to study various conditions, disorders or diseases modified by adenosine .
|
-
- HY-W854187
-
|
5'-DMT-2'-OMe-rG(N-Ac) Phosphoramidite
|
|
Nucleoside Phosphoramidites
Guanine
|
|
2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac)) Phosporamiditeyes 2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac))Phosphoramidite.
|
-
- HY-W425093
-
-
- HY-W036167
-
-
- HY-153249
-
-
- HY-W579407
-
-
- HY-153251
-
-
- HY-W018179
-
-
- HY-153253
-
-
- HY-W579408
-
-
- HY-W093086
-
-
- HY-21713
-
-
- HY-W783407
-
-
- HY-W579410
-
-
- HY-160884
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides .
|
-
- HY-138579
-
|
DMT-2'-O-Methyl-rG(ib) Phosphoramidite
|
|
Nucleoside Phosphoramidites
Guanine
|
|
2'-OMe-G(ibu) Phosphoramidite (DMT-2'-O-Methyl-rG(ib) Phosphoramidite) is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis .
|
-
- HY-45491
-
|
2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
|
|
Nucleoside Phosphoramidites
Cytosine
|
|
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
|
-
- HY-W700549
-
-
- HY-46317
-
|
|
|
Nucleoside Phosphoramidites
Cytosine
|
|
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding .
|
-
- HY-W101391
-
|
2'-O-Me-U Phosphoramidite
|
|
Nucleoside Phosphoramidites
Uracil
|
|
DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis .
|
-
- HY-21997
-
|
|
|
Nucleoside Phosphoramidites
Adenine
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-W013059A
-
|
L-DA-CE phosphoramidite
|
|
Nucleoside Phosphoramidites
Adenine
|
|
DMT-L-dA(bz) Phosphoramidite (L-DA-CE phosphoramidite; compound 20c) is typically used in the synthesis of DNA. DMT-L-dA(bz) Phosphoramidite can be used in studying DNA-drug interactions .
|
-
- HY-164252
-
|
5′-O-Trityl-2′-deoxy-2′-fluorouridine
|
|
Nucleoside Analogs
Uridine
|
|
DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
|
-
- HY-138607
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-138613
-
|
|
|
Nucleoside Analogs
Inosine
|
|
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-W114886
-
-
- HY-W115186
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154413
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-45492
-
|
2'-F-ibu-dG Phosphoramidite
|
|
Nucleoside Phosphoramidites
Guanine
|
|
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
|
-
- HY-W013068
-
-
- HY-138601
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
5'-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-W013059
-
-
- HY-W570893
-
-
- HY-W008849
-
-
- HY-49210
-
-
- HY-49000
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-locMeC(bz) phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-138608
-
-
- HY-138585
-
-
- HY-138581
-
-
- HY-49200
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-164181
-
-
- HY-138609
-
-
- HY-138605
-
-
- HY-138606
-
-
- HY-139988
-
|
|
|
Nucleoside Phosphoramidites
|
|
2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W460666
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-DMT-N2-Ibu-2'-OMe-G is a crucial intermediate for the synthesis of antisense oligonucleotides. 5'-O-DMT-N2-Ibu-2'-OMe-G is involved in constructing antisense oligonucleotides with specific sequences, which can bind complementarily to the targeted mRNA. 5'-O-DMT-N2-Ibu-2'-OMe-G blocks the translation process of mRNA, thereby inhibiting the expression of specific proteins and playing a role in regulating gene expression. 5'-O-DMT-N2-Ibu-2'-OMe-G is promising for research of genetic diseases and tumors .
|
- HY-164249
-
- HY-W102322
-
- HY-21545
-
- HY-138610
-
- HY-W008848
-
- HY-132136
-
- HY-154366
-
|
N1-Methylpseudouridine CEP
|
|
Nucleoside Phosphoramidites
Uracil
|
|
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W784557
-
|
|
|
Nucleoside Phosphoramidites
|
|
O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
|
- HY-138586
-
- HY-W793155
-
|
|
|
Nucleoside Analogs
Adenosine
|
|
N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that is structurally related to the natural nucleotide adenosine. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides.
|
- HY-138600
-
- HY-W008848A
-
|
|
|
Nucleoside Phosphoramidites
Guanine
|
|
DMT-L-dG(ib) Phosphoramidite (Compound 20D) is a nucleoside phosphoramidite that can be used for nucleotide assembly on solid supports .
|
- HY-138604
-
- HY-138614
-
- HY-138611
-
- HY-138603
-
- HY-138612
-
- HY-43059
-
|
5'-O-DMT-2'-O-TBDMS-ibu-rG
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides .
|
- HY-W091754
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.
|
- HY-W077279
-
|
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
|
|
Nucleoside Analogs
Cytidine
|
|
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
|
- HY-21601
-
|
|
|
Nucleoside Analogs
Adenosine
|
|
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
|
- HY-W336559
-
- HY-43058
-
|
5'-O-DMT-N2-isobutyrylguanosine
|
|
Nucleoside Phosphoramidites
Guanine
|
|
5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents .
|
- HY-173175
-
- HY-138602
-
- HY-138598
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
- HY-20140
-
|
5'-O-(4,4'-Dimethoxytrityl)thymidine
|
|
Nucleoside Analogs
Thymidine
|
|
5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides .
|
- HY-48873
-
|
|
|
Nucleoside Phosphoramidites
Uracil
|
|
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-46369
-
|
|
|
Nucleoside Phosphoramidites
Uracil
|
|
1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-W042357
-
|
|
|
Nucleoside Phosphoramidites
Cytosine
|
|
Ac-rC Phosphoramidite is a phosphoramidite containing 5’ DMT and the nucleoside cytiding with Acetyl base protection. Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA) .
|
- HY-W087199
-
|
|
|
Nucleoside Phosphoramidites
Adenine
|
|
N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-W114328
-
|
N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
|
|
Nucleoside Analogs
Cytidine
|
|
DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides .
|
- HY-152970
-
|
|
|
Nucleoside Analogs
Uridine
|
|
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-W008662
-
|
|
|
Nucleoside Analogs
Uridine
|
|
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
|
- HY-W726201
-
|
|
|
Nucleoside Phosphoramidites
Uracil
|
|
2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.
|
- HY-104039
-
|
|
|
Nucleoside Phosphoramidites
Cytosine
|
|
2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-W010702
-
|
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides .
|
- HY-154019
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154410
-
|
|
|
Nucleoside Analogs
Uridine
|
|
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-152978
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154309
-
|
|
|
Nucleoside Analogs
Adenosine
|
|
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154604
-
|
|
|
Nucleoside Phosphoramidites
Thymine
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
- HY-154363
-
|
|
|
Nucleoside Analogs
|
|
3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154267
-
|
|
|
Nucleoside Analogs
Uridine
|
|
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154450
-
|
|
|
Nucleoside Analogs
Cytidine
|
|
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154229
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154030
-
|
|
|
Nucleoside Analogs
Adenosine
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N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152979
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Nucleoside Phosphoramidites
Cytosine
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2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154441
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Nucleoside Analogs
Cytidine
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N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154221
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Nucleoside Analogs
Cytidine
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N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154260
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Nucleoside Analogs
Adenosine
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N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154207
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Nucleoside Phosphoramidites
Cytosine
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2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152988
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Nucleoside Analogs
Guanosine
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N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
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- HY-152973
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Nucleoside Analogs
Thymidine
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7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-154350
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Nucleoside Analogs
Guanosine
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5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
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- HY-138589
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Nucleoside Analogs
Guanosine
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5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-154548
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Nucleoside Analogs
Guanosine
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N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
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- HY-152984
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Nucleoside Analogs
Adenosine
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N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-W097792
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5'-O-DMT-dU
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Nucleoside Analogs
Uridine
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5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
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- HY-154464
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Nucleoside Analogs
Guanosine
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N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
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- HY-45281
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Nucleoside Phosphoramidites
Adenine
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N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-152983
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Nucleoside Phosphoramidites
Adenine
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2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-154419
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Nucleoside Analogs
Adenosine
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N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-154339
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Nucleoside Analogs
Adenosine
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N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-W141392
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Nucleoside Phosphoramidites
Hypoxanthine
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
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- HY-W392836
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Nucleoside Phosphoramidites
Hypoxanthine
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2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
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- HY-W010706
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5'-O-DMT-N4-Bz-dC
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Nucleoside Analogs
Cytidine
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N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
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