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Complement C3/C3a

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Complement System (4) NF-κB (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Inflammation/Immunology (4)

4

Inhibitors & Agonists

2

Peptides

8

Recombinant Proteins

Targets Recommended: Complement System

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

C3a (70-77) TFA 1 Publications Verification Complement 3a (70-77) TFA	Complement System	Inflammation/Immunology
C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a .

JR14a Maximum Cited Publications 8 Publications Verification	Complement System	Inflammation/Immunology
JR14a is a potent thiophene antagonist of *human complement* C3a receptor*. JR14a shows selectivity for the human C3a* receptor over C5a receptor. JR14a can suppress C3aR-mediated inflammation .

C3a (70-77) Complement 3a (70-77)	Complement System	Inflammation/Immunology
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.

4-Octylphenol	Complement System Toll-like Receptor (TLR) NF-κB	Inflammation/Immunology
4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the *C3a/C3aR* axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway .

Cat. No.	Product Name	Target	Research Area

C3a (70-77) TFA 1 Publications Verification Complement 3a (70-77) TFA	Complement System	Inflammation/Immunology
C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a .

C3a (70-77) Complement 3a (70-77)	Complement System	Inflammation/Immunology
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.

Species:	Human (4) Mouse (2) Bovine (1) Cynomolgus (1)
Tag:	His (5) SUMO (1) Tag Free (2) Avi (1) Fc (1)
Source:	HEK293 (5) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

	Complement C3 Protein, Cynomolgus (HEK293, His) Anaphylatoxin; C3; Complement Component C3a	Cynomolgus	HEK293
	Complement C3 proteins play a key role in initiating the complement system through processing by C3 convertase in the classical and alternative pathways. Upon activation, C3b covalently binds to the surface, while C3a (anaphylatoxin produced by proteolysis of C3) mediates local inflammation. Complement C3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Complement C3 protein, expressed by HEK293 , with C-His labeled tag.

	Complement C3 Protein, Mouse (HEK293, His) Complement C3; HSE-MSF; C3; CPAMD1; AHUS5; ARMD9; ASP; C3a; C3b; HEL-S-62p	Mouse	HEK293
	Complement C3 protein activates the complement system, playing a central role in both classical and alternative pathways. C3b binds covalently to cell surface carbohydrates or immune aggregates, while C3a acts as an inflammatory mediator, inducing neutrophil chemoattraction and promoting smooth muscle contraction, increased vascular permeability, and histamine release. The shorter isoform of C3a stimulates B-cells. Complement C3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Complement C3 protein, expressed by HEK293 , with C-His labeled tag.

	Complement C3 Protein, Human (HEK293, His) Complement C3; HSE-MSF; C3; CPAMD1; AHUS5; ARMD9; ASP; C3a; C3b; HEL-S-62p	Human	HEK293
	Complement C3 protein activates the complement system, playing a central role in both classical and alternative pathways. C3b binds covalently to cell surface carbohydrates or immune aggregates, while C3a acts as an inflammatory mediator, inducing neutrophil chemoattraction and promoting smooth muscle contraction, increased vascular permeability, and histamine release. The shorter isoform of C3a stimulates B-cells. Complement C3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Complement C3 protein, expressed by HEK293 , with C-10*His labeled tag.

	Complement C3a Protein, Human 5 Publications Verification rHuComplement C3/C3a; Complement Component C3a; C3a; Anaphylatoxin	Human	E. coli
	Complement C3/C3a protein plays a key role in initiating the complement system through processing by C3 convertase in both the classical and alternative pathways. Complement C3/C3a protein is involved in various immune and inflammatory responses and also has a role in regulating blood pressure. Complement C3a Protein, Human is a recombinant Complement C3/C3a protein expressed in E. coli, no tag..

	Complement C3a Protein, Mouse 5+ Cited Publications rMuComplement C3/C3a; Complement Component C3a; Anaphylatoxin; C3a	Mouse	E. coli
	Complement C3/C3a protein activates the complement system, playing a central role in both classical and alternative pathways. C3b binds covalently to cell surface carbohydrates or immune aggregates, while C3a acts as an inflammatory mediator, inducing neutrophil chemoattraction and promoting smooth muscle contraction, increased vascular permeability, and histamine release. The shorter isoform of C3a stimulates B-cells. Complement C3a Protein, Mouse is the recombinant mouse-derived Complement C3/C3a protein, expressed by E. coli , with tag free.

	Complement C3a Protein, Bovine (His-SUMO) C3Complement C3; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]	Bovine	E. coli
	Complement C3/C3a proteins play a key role in initiating the complement system, serving as substrates for C3 convertase in both the classical and alternative pathways. Upon activation, C3 undergoes proteolytic cleavage, yielding C3b, which is covalently bound to surface or immune aggregates. Complement C3a Protein, Bovine (His-SUMO) is the recombinant bovine-derived Complement C3/C3a protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

	Complement C3 Protein, Human (HEK293, hFc) Complement C3; HSE-MSF; C3; CPAMD1; AHUS5; ARMD9; ASP; C3a; C3b; HEL-S-62p	Human	HEK293
	Complement C3/C3a proteins play a key role in initiating the complement system through processing by C3 convertase in the classical and alternative pathways. Upon activation, C3b covalently binds to the surface, while C3a (anaphylatoxin produced by proteolysis of C3) mediates local inflammation. Complement C3 Protein, Human (HEK293, hFc) is the recombinant human-derived Complement C3 protein, expressed by HEK293, with C-hFc labeled tag.

	Complement C3 Protein, Human (Biotinylated, HEK293, His-Avi) Complement C3; HSE-MSF; C3; CPAMD1; AHUS5; ARMD9; ASP; C3a; C3b; HEL-S-62p	Human	HEK293

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